Abstract:
:A phase II study indicates that sacituzumab govitecan (IMMU-132), a Trop-2-specific antibody linked to the irinotecan metabolite SN-38, prolongs the progression-free survival of patients with advanced triple-negative breast cancer. IMMU-132 is well tolerated, causing fewer and more manageable side effects than irinotecan.
journal_name
Cancer Discovjournal_title
Cancer discoveryauthors
doi
10.1158/2159-8290.CD-NB2015-162subject
Has Abstractpub_date
2016-01-01 00:00:00pages
OF8issue
1eissn
2159-8274issn
2159-8290pii
2159-8290.CD-NB2015-162journal_volume
6pub_type
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