Abstract:
:Recent results suggest that tucatinib, when combined with trastuzumab and capecitabine, is effective in patients with locally advanced inoperable or metastatic HER2-positive breast cancer who have received prior therapies: In a phase II trial, the drug extended overall survival and progression-free survival compared with trastuzumab and capecitabine alone, and improved progression-free survival in patients with brain metastases.
journal_name
Cancer Discovjournal_title
Cancer discoveryauthors
doi
10.1158/2159-8290.CD-NB2019-135subject
Has Abstractpub_date
2020-01-01 00:00:00pages
7issue
1eissn
2159-8274issn
2159-8290pii
2159-8290.CD-NB2019-135journal_volume
10pub_type
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