Emergent mechanical thrombectomy for acute stroke using the Mindframe Capture LP system: initial single-center experience.

Abstract:

BACKGROUND:Mechanical thrombectomy using stentrievers is the standard of care for emergent large vessel occlusion stroke. Data on the use of stentrievers in smaller caliber vessels are sparse. OBJECTIVE:To present our initial experience with the Mindframe Capture LP device, which was designed for mechanical thrombectomy in small cerebral arteries. METHODS:A retrospective chart review was conducted of patients who underwent Mindframe device assisted emergent thrombectomy. Clinical, imaging, procedural and early follow-up data were obtained. RESULTS:Nine patients met inclusion criteria (5 men, median age 62 years). Median National Institute of Health Stroke Scale (NIHSS) score was 18 (IQR 9-22), and 6 patients received intravenous tissue plasminogen activator. Six patients had M2 segment occlusions, and 2 patients had distal M1 segment occlusions of the middle cerebral artery. One had distal basilar artery occlusion. Median vessel diameter at the thrombus was 1.7 mm (IQR 1.5-2.5). In all 9 patients the Mindframe device was used together with manual aspiration, with median groin puncture to recanalization time of 35 min (IQR 27-54), and median procedural time of 67 min (IQR 51-91). Final Thrombolysis in Cerebral Infarction score was 3 and 2b in 4 patients each (89% total), and 2a in 1 patient. No patient had any postprocedural complications or symptomatic intracerebral hemorrhage. Median postprocedure and discharge NIHSS were 4 and 1, respectively. CONCLUSIONS:Our data suggest that the Mindframe device is safe and effective for rapid treatment of acute strokes involving small caliber intracranial vessels. Further study in a larger cohort is warranted.

journal_name

J Neurointerv Surg

authors

Cerejo R,John S,Bauer A,Hussain MS,Bain M,Rasmussen P,Hui F,Masaryk T,Toth G

doi

10.1136/neurintsurg-2015-012078

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

1178-1180

issue

11

eissn

1759-8478

issn

1759-8486

pii

neurintsurg-2015-012078

journal_volume

8

pub_type

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