Abstract:
BACKGROUND:Leprosy is an infectious disease that may lead to irreversible nerve damage, compromising patient's quality of life and leading to loss of working years. OBJECTIVES:To evaluate the epidemiological profile of patients followed at a University Hospital. MATERIALS AND METHODS:This is a retrospective observational study, based on a review of medical records. We studied the clinical and epidemiological features of patients with leprosy monitored at the Hospital de Clínicas of the Federal University of Paraná between January 2005 and January 2010. RESULTS:The mean age was 47.51, while 35.94% of patients were aged 41-60. The male:female rate was 1.8:1. The most prevalent occupations were: retired, students or rural workers. Patients came mainly from Curitiba or nearby areas, but there were also patients from the countryside. The mean diagnostic delay was 24.57 months. Multibacillary forms prevailed, with the lepromatous variety being the most common, closely followed by the borderline type. Neural enlargement was found in more than 50% of the patients and 48.44% of them developed reactional states. Hemolysis was the most commonly detected drug side effect. Initial functional evaluation was possible in 70% of patients, 55% of whom had disabilities upon diagnosis. The most prevalent associated disease was hypertension. CONCLUSIONS:This study showed an important diagnostic delay and a high rate of sequelae in this specific population. Brazil is one of the few remaining countries that has not yet eradicated leprosy and it is important to improve health policies in order to prevent sequelae and achieve eradication.
journal_name
An Bras Dermatoljournal_title
Anais brasileiros de dermatologiaauthors
Lima AS,Pinto KC,Bona MP,Mattos SM,Hoffmann MP,Mulinari-Brenner FA,Ottoboni VCdoi
10.1590/abd1806-4841.20153959subject
Has Abstractpub_date
2015-09-01 00:00:00pages
654-9issue
5eissn
0365-0596issn
1806-4841pii
S0365-05962015000500654journal_volume
90pub_type
杂志文章abstract::Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatolo...
journal_title:Anais brasileiros de dermatologia
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doi:10.1590/abd1806-4841.20175561
更新日期:2017-05-01 00:00:00
abstract::Chromoblastomycosis is a subcutaneous mycosis caused by the dermatophytic fungi Fonsecaea, Phialophora and Cladophialophora. Usual complications include secondary infection, lymphedema and elephantiasis. Associated malignancies have been found in chronic cases. This case report describes a 72 year-old male with a 30 y...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962010000200025
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abstract::Wolf's isotopic response designates the appearance of two subsequent unrelated dermatoses in the same anatomic location. We report the case of a 51-year-old man with a medical history of chronic lymphocytic leukemia without known extra-hematopoietic involvement. The patient developed a disseminated papulo-vesiculous e...
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doi:10.1590/abd1806-4841.20164686
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:In this study, cases with suspected urethral condylomata acuminata were examined by dermoscopy, in order to explore an effective method for clinical. OBJECTIVE:To study the application of dermoscopy image analysis technique in clinical diagnosis of urethral condylomata acuminata. METHODS:A total of 220 sus...
journal_title:Anais brasileiros de dermatologia
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abstract:BACKGROUND:Dermatology encompasses the management of many disorders of the skin and cutaneous appendages, making the analysis of epidemiological profiles relevant for health planning. OBJECTIVE:The study aims to describe the nosological profile of dermatological diseases in Florianopolis, analyzing the interrelation a...
journal_title:Anais brasileiros de dermatologia
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doi:10.1016/j.abd.2020.01.004
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abstract::Blastic plasmacytoid dendritic cell tumor is a rare, highly aggressive systemic neoplasm for which effective therapies have not yet been established. We describe a 73-year-old man with multiple nodules and patches emerging on the trunk and limbs. Lesional skin biopsy revealed a plasmacytoid dendritic cell tumor with d...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962013000100022
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abstract::Congenital self-healing reticulohistiocytosis is the benign spectrum of Langerhans Cell Histiocytosis, characterized by cutaneous lesions at birth or in the neonatal period, absence of systemic manifestations and spontaneous resolution of clinical status. Despite the benign and often self-resolving course in most pati...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000400026
更新日期:2011-07-01 00:00:00
abstract::Trichotillomania is a psychodermatologic disorder characterized by uncontrollable urge to pull one's own hair. Differential diagnoses include the most common forms of alopecia such as alopecia areata. It is usually associated with depression and obsessive-compulsive disorder. Trichotillomania treatment standardization...
journal_title:Anais brasileiros de dermatologia
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doi:10.1590/abd1806-4841.20175136
更新日期:2017-01-01 00:00:00
abstract::Neonatal skin suffers a progressive adaptation to the extrauterine environment and special care is needed during this period. This skin is very sensitive, thin and fragile. Immaturity of the epidermal barrier reduces the defense against the excessive proliferation of microbes and makes the skin more vulnerable to trau...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章,评审
doi:10.1590/s0365-05962011000100014
更新日期:2011-01-01 00:00:00
abstract::Sporothrix spp. infection can occur through the inoculation of the organism in the skin through direct contact with the soil (sapronotic infection), through contact with animals, such as infected cats and dogs (zoonotic infection), or less frequently via inhalation. With a subacute or chronic evolution, approximately ...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1016/j.abd.2019.11.015
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Female pattern hair loss (FPHL) is a common complaint in adult women and inflicts major impact in quality of life, however, there is no specific questionnaire available in Portuguese for such evaluation. OBJECTIVES:Translation into Brazilian Portuguese, cultural adaptation and validation of the WAA-QoL (Wom...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20187452
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abstract::Actinic keratoses are premalignant lesions of the skin caused by excessive sun exposure. Lesions may become mainly squamous cell carcinoma. Cryotherapy with liquid nitrogen is one of the main treatments. In order to evaluate the response of actinic keratosis to cryotherapy by histopathology, two lesions were selected ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20153302
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:There have been few studies on pentamidine in the Americas; and there is no consensus regarding the dose that should be applied. OBJECTIVES:To evaluate the use of pentamidine in a single dose to treat cutaneous leishmaniasis. METHODS:Clinical trial of phase II pilot study with 20 patients. Pentamidine was ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20153956
更新日期:2015-11-01 00:00:00
abstract::Basal Cell Carcinoma is the most common skin cancer. We describe a single-staged technique for correction of nasal ala defect after the excision of a basal cell carcinoma. This technique allows correction of surgical defects of the ala rebuilding the original anatomy, maintaining cosmetic units, without need for a gra...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000700042
更新日期:2011-07-01 00:00:00
abstract::The recent development of high-frequency ultrasound, associated with the improved sensitivity in color Doppler, enabled the identification of various skin structures and layers. In basal cell carcinoma, the 22 MHz frequency ultrasound permits the delimitation of tumor margins, while color Doppler, determines its vascu...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20143176
更新日期:2014-09-01 00:00:00
abstract::Parry-Romberg syndrome, also known as progressive hemifacial atrophy, is a rare disorder characterized by slow and progressive hemifacial atrophy. The treatment offered for the syndrome generally aims at improving aesthetics. Fat grafts, silicone injections or acrylic prosthesis are alternatives suggested for correcti...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章,评审
doi:10.1590/s0365-05962011000700022
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Lichen planus is considered to be the most common dermatological disease involving the oral mucosa. OBJECTIVE:To investigate the profile, clinical features, and the presence of dysplasia and candidiasis in patients with oral lichen planus. METHODS:A total of 21 patients were selected from 258 patients at r...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20153704
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Actinic keratosis (AK) represents a risk of progression to squamous cell carcinoma. Ingenol mebutate gel is a novel therapeutic option for field-directed treatment. OBJECTIVES:To evaluate the safety, tolerability and patients' perspectives, related to the therapeutic success of managing AKs on the face and ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20197938
更新日期:2019-07-29 00:00:00
abstract:BACKGROUND:assessment instruments of nail psoriasis have been published in literature as means to standardize the previous subjective assessments of authors. OBJECTIVES:Using Nail Psoriasis Severity Index for evaluation in patients with plaque psoriasis during treatment with acitretin. METHODS:Thirty volunteers with ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962012000200010
更新日期:2012-03-01 00:00:00
abstract::Muckle-Wells syndrome is a rare autosomal dominant disease that belongs to a group of hereditary febrile syndromes. It is characterized by recurrent and self-limited episodes of fever, urticaria, arthralgia, myalgia and conjunctivitis since childhood, which are related to exposure to cold temperatures. Lately, progres...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962010000600022
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Myeloid leukemia cutis is the terminology used for cutaneous manifestations of myeloid leukemia. OBJECTIVE:The purpose of this study was to study the clinical, histopathological and immunohistochemical features of myeloid leukemia cutis. METHODS:This was a retrospective study of clinical and pathological f...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20186327
更新日期:2018-03-01 00:00:00
abstract::Vegetative chronic genital herpes is an atypical presentation of herpes simplex 2 that it is usually seen in patients coinfected with human immunodeficiency virus. Clinically, it is characterized by extensive ulcers that evolve to chronification and hypertrophic pseudotumor forms. Antiviral drugs are recommended for t...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1590/abd1806-4841.20198014
更新日期:2019-03-01 00:00:00
abstract::Dermatofibroma is a proliferation of spindle cells located in the dermis. We used scanning electron microscopy to examine two histologically confirmed lesions and observed preserved collagen bundles in the perilesional area. In the lesional area, the collagen was denser, without formation of bundles. Higher magnificat...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20197906
更新日期:2019-07-29 00:00:00
abstract::Ultraviolet radiation can damage the DNA, cause immunosuppression, chemical and histological alterations in the epidermis, early photoaging, cataracts and carcinogenesis, among others. Photoprotection prevents these and other harmful effects of ultraviolet radiation. Sunscreens, protective clothing, proper accessories...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章,评审
doi:10.1590/s0365-05962011000400016
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Vitiligo is a chronic disease characterized by the appearance of achromic macules caused by melanocyte destruction. Surgical treatments with melanocyte transplantation can be used for stable vitiligo cases. OBJECTIVES:To evaluate treatment response to the autologous transplantation of noncultured epidermal ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20175700
更新日期:2017-05-01 00:00:00
abstract::Primary cutaneous B-cell lymphomas (PCBCLs) constitute 25% of all primary cutaneous lymphomas. They present in the skin with no evidence of systemic or extracutaneous disease at the time of diagnosis, after adequate staging. Primary cutaneous B-cell lymphomas differ significantly from their nodal counterparts in relat...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20153768
更新日期:2015-05-01 00:00:00
abstract::Paracoccidioidomycosis is an endemic systemic mycosis in Brazil, frequent in the rural areas and often in adult men. It is reported the case of a farmer, who is an illicit drugs' user, with insidious manifestations affecting kidneys, lungs, lymphonodes, bones and lately, the skin, with a delay of more than one year in...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/s0365-05962011000100024
更新日期:2011-01-01 00:00:00
abstract::Agminated nevus is a cluster group of melanocytic nevi confined to a localized area of the body. There are many pigmented lesions described in the literature as agminated, such as blue nevi, multiple lentigines and Spitz nevi, but only a few cases of congenital agminated melanocytic nevi have been described. We report...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20132137
更新日期:2013-11-01 00:00:00
abstract::Distinct cases of Paracoccidioidomycosis and Cryptococcosis with atypical and localized skin manifestation on the upper limbs of two elderly patients are reported. In the 2nd one, he presented asymptomatic pulmonary cancer; the blood tests for fungal infection were negative, and the etiologic agents were seen in skin ...
journal_title:Anais brasileiros de dermatologia
pub_type: 杂志文章
doi:10.1590/abd1806-4841.20164061
更新日期:2016-04-01 00:00:00
abstract::Porokeratosis represents a group of disorders of epidermal keratinization that are characterized by one or more annular plaques surrounded by a histologically distinctive hyperkeratotic ridge-like border called the cornoid lamella. Many studies showed that organ transplantation and immunosuppression were associated in...
journal_title:Anais brasileiros de dermatologia
pub_type:
doi:10.1590/abd1806-4841.20164253
更新日期:2016-09-01 00:00:00