Association of Bisphenol A Exposure With Hypertension and Early Macrovascular Diseases in Chinese Adults: A Cross-Sectional Study.


:Bisphenol A (BPA) is an environmental endocrine disruptor that has been associated with cardiovascular outcomes in previous observational studies. We aimed to examine the relationships of urinary BPA levels with hypertension and early macrovascular diseases.This is a cross-sectional study. From June through August 2009, 3246 participants ages 40 years or older were enrolled from Baoshan District, Shanghai, China. Logistic regression modes were used to estimate the odds ratios (ORs) for prevalent risk of hypertension, elevated carotid intima-media thickness (CIMT), arterial stiffness, and peripheral artery disease (PAD) with multivariable adjustment. We also performed stratification analysis by age and sex.The median (interquartile range) for BPA was 0.81 (0.48, 1.45) ng/mL, which is notably lower than previously reported in the United States and other Western countries. Urinary BPA concentrations were negatively associated with hypertension (multivariable-adjusted OR for the highest versus lowest BPA quartile = 0.61; 95% confidence interval [CI]: 0.46, 0.80), elevated CIMT (OR = 0.64; 95% CI: 0.47, 0.87), and arterial stiffness (OR = 0.62; 95% CI: 0.44, 0.87). The corresponding OR for PAD (60 cases total) was not significant (OR = 0.89; 95% CI: 0.28, 2.80). The negative associations of BPA with hypertension, elevated CIMT, and arterial stiffness were consistent by age and sex stratifications, and were stronger among participants ≥60 versus <60 years of age, and among women than men.In contrast with previous investigations, our study suggests negative associations of BPA exposure with hypertension and early macrovascular diseases among middle-aged and elderly Chinese. Future investigations are needed to draw more definite conclusions and generalize to other populations.


Medicine (Baltimore)




Wang T,Xu M,Xu Y,Lu J,Li M,Chen Y,Wang W,Lai S,Bi Y,Ning G




Has Abstract


2015-10-01 00:00:00
















  • Association between condom use and perspectives on contraceptive responsibility in different sexual relationships among sexually active college students in China: A cross-sectional study.

    abstract::China has increasing incidence of unplanned pregnancies among college students these years. Increasing students' sense of responsibility to protect sexual partners may help reduce the rate of unplanned pregnancies.A self-administered questionnaire was distributed to students from 3 colleges in Sichuan, China. Among th...


    pub_type: 杂志文章


    authors: Long L,Han Y,Tong L,Chen Z

    更新日期:2019-01-01 00:00:00

  • Coexistence of nontuberculous mycobacterium and IgG4-related disease in a solitary pulmonary nodule: A case report.

    abstract:RATIONALE:Immunoglobulin G4-related disease (IgG4-RD) is regarded as an immune-mediated systemic fibroinflammatory disease. Several studies have linked IgG4-RD to infections such as tuberculosis and actinomycosis. However, the coexistence of IgG4-RD and non-tuberculous mycobacterium (NTM) in a single pulmonary nodule h...


    pub_type: 杂志文章


    authors: Bae K,Jung An H,Jeon KN,Hyun Song D,Kim SH,Kim HC

    更新日期:2019-11-01 00:00:00

  • Usefulness of Ultrasonography for Diagnosis of Small Bowel Tumors: A Comparison Between Ultrasonography and Endoscopic Modalities.

    abstract::Ultrasonography is a standard, noninvasive modality used to evaluate patients with gastrointestinal diseases. This study assessed the usefulness of ultrasonography in the detection of small bowel tumors. This study enrolled 558 consecutive patients (295 males, 263 females; mean age 71.1 years) who underwent ultrasonog...


    pub_type: 杂志文章


    authors: Fujita M,Manabe N,Honda K,Murao T,Osawa M,Kawai R,Akiyama T,Shiotani A,Haruma K,Hata J

    更新日期:2015-10-01 00:00:00

  • Validation of Serological Antibody Profiles Against Human Papillomavirus Type 16 Antigens as Markers for Early Detection of Cervical Cancer.

    abstract::Cervical cancer (CC) is the second most frequent neoplasia among women worldwide. Cancer prevention programs around the world have used the Papanicolaou (Pap) smear as the primary diagnostic test to reduce the burden of CC. Nevertheless, such programs have not been effective in developing countries, thus leading to re...


    pub_type: 杂志文章


    authors: Salazar-Piña DA,Pedroza-Saavedra A,Cruz-Valdez A,Ortiz-Panozo E,Maldonado-Gama M,Chihu-Amparan L,Rodriguez-Ocampo AN,Orozco-Fararoni E,Esquivel-Guadarrama F,Gutierrez-Xicotencatl L

    更新日期:2016-02-01 00:00:00

  • Successful treatment with rivaroxaban of cerebral venous thrombosis and bone marrow necrosis induced by pegaspargase: A case report and literature review.

    abstract:RATIONALE:Pegaspargase has been used in the treatment of acute lymphoblastic leukemia with promising results. However, it has also been associated with several potentially serious complications, including thrombosis. Pegaspargase-induced cerebral venous thrombosis and bone marrow necrosis are very rare. PATIENT CONCER...


    pub_type: 杂志文章,评审


    authors: Sui J,Zhang Y,Yang L,Wang H,Xu J,Wei R,Hao Y,Wang X,Peng J,Ma J

    更新日期:2017-11-01 00:00:00

  • Fractures as a suicidal behavior risk factor: A nationwide population-based cohort study.

    abstract::This study aimed to evaluate the association between fracture history and sequential risk of suicidal behavior.A total of 82,804 patients with fractures and 82,804 control subjects without fractures were matched. The influence of fractures on the risk of suicidal behavior-related hospital visit was analyzed using a Co...


    pub_type: 杂志文章


    authors: Tsai CH,Cheng WJ,Muo CH,Lin TL

    更新日期:2019-01-01 00:00:00

  • Reduning injection combined with western medicine for pneumonia: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Pneumonia is a common respiratory disease. In severe cases, it can induce cardiovascular disease and even life-threatening. In particular, pneumonia caused by the new coronavirus (SARS-CoV-2) that broke out at the end of 2019 has seriously affected the health of people in all countries. In recent years, it h...


    pub_type: 杂志文章,meta分析


    authors: Cao C,Zhen Z,Kuang S,Xu T

    更新日期:2020-10-23 00:00:00

  • Successful management of perivascular epithelioid cell tumor of the rectum with recurrent liver metastases: A case report.

    abstract:RATIONALE:The perivascular epithelioid cell tumor (PEComa) is rare in young man and rarely occurs in the large intestine. PATIENT CONCERNS:The clinical characteristics, diagnosis, and managements in a 28-year-old boy who presented with sudden onset of cramping and abdominal pain and intermittent melena with a blood pr...


    pub_type: 杂志文章


    authors: Lin KH,Chang NJ,Liou LR,Su MS,Tsao MJ,Huang ML

    更新日期:2018-08-01 00:00:00

  • The Incidence of Deep Vein Thrombosis in Asian Patients With Chronic Obstructive Pulmonary Disease.

    abstract::Most studies have focused on the prevalence of deep vein thrombosis (DVT) and pulmonary embolism in patients with chronic obstructive pulmonary disease (COPD) and acute exacerbation in Caucasian populations. DVT is supposedly less likely to occur among Asians than Caucasians, and the primary purpose of this study was ...


    pub_type: 杂志文章


    authors: Chen CY,Liao KM

    更新日期:2015-11-01 00:00:00

  • Association between Helicobacter pylori infection and irritable bowel syndrome: A systematic review and meta-analysis.

    abstract:BACKGROUND:In recent years, the incidence of IBS has gradually increased, and it is considered as one of the most common functional gastrointestinal diseases. However, the etiology of IBS is still unclear, and expectations are rising for more targeted treatments. Many clinical trials have explored the link between Heli...


    pub_type: 杂志文章,meta分析


    authors: Li C,Shuai Y,Zhou X,Chen H

    更新日期:2020-12-11 00:00:00

  • Coreceptor usage of Chinese HIV-1 and impact of X4/DM transmission clusters among recently infected men who have sex with men.

    abstract::To characterize the current frequency of HIV-1 coreceptor usage in China and assess the candidacy of CCR5 antagonists for treatment of HIV infections. In addition, we aimed to evaluate the potential of X4/DM virus transmission in recently infected men who have sex with men (MSM) individuals.Viral tropism testing was p...


    pub_type: 杂志文章


    authors: Li X,Zhu K,Li W,Fang K,Musa TH,Song Y,Du G,Gao R,Guo Y,Yan W,Xuan Y,Zhong P,Wei P

    更新日期:2016-09-01 00:00:00

  • Relation between primary tumor FDG avidity and site of first distant metastasis in patients with breast cancer.

    abstract::Identification of tumor imaging features associated with metastatic pattern may allow better understanding of cancer dissemination. Here, we investigated how primary tumor F-fluorodeoxyglucose (FDG) avidity influences the first site of breast cancer metastasis.Subjects were 264 patients with advanced breast cancer who...


    pub_type: 杂志文章


    authors: Lim CH,Moon SH,Cho YS,Im YH,Choe YS,Kim BT,Lee KH

    更新日期:2016-08-01 00:00:00

  • Electroacupuncture for patients with diarrhea-predominant irritable bowel syndrome or functional diarrhea: A randomized controlled trial.

    abstract::Diarrhea-predominant irritable bowel syndrome (IBS-D) and functional diarrhea (FD) are highly prevalent, and the effectiveness of acupuncture for managing IBS-D and FD is still unknown.The aim of this study was to compare the effectiveness of electroacupuncture with loperamide.It was a prospective, randomized, paralle...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Zheng H,Li Y,Zhang W,Zeng F,Zhou SY,Zheng HB,Zhu WZ,Jing XH,Rong PJ,Tang CZ,Wang FC,Liu ZB,Wang SJ,Zhou MQ,Liu ZS,Zhu B

    更新日期:2016-06-01 00:00:00

  • Long non-coding RNA zinc finger antisense 1 expression associates with increased disease risk, elevated disease severity and higher inflammatory cytokines levels in patients with lumbar disc degeneration.

    abstract::This study aimed to investigate the correlation of long noncoding RNA zinc finger antisense 1 (lncRNA ZFAS1) expression with disease risk, disease severity and inflammatory cytokines levels in lumbar disc degeneration (LDD) patients.83 LDD patients underwent surgery and 28 traumatized, non-LDD patients underwent lumba...


    pub_type: 杂志文章


    authors: Deng RY,Hong T,Li CY,Shi CL,Liu C,Jiang FY,Li J,Fan XM,Feng SB,Wang YF

    更新日期:2019-12-01 00:00:00

  • Obesity and metabolic syndrome in children in Brazil: The challenge of lifestyle change.

    abstract::The purpose of this observational study was to examine the prevalence of obesity in children of 6 to 8 years of age from primary public schools over a period of 6 years and the associated environmental and metabolic health risk factors.This was a cohort observational study to investigate the prevalence of obesity in c...


    pub_type: 杂志文章


    authors: Sentalin PBR,Pinheiro AO,Oliveira RR,Zângaro RA,Campos LA,Baltatu OC

    更新日期:2019-05-01 00:00:00

  • Erratum: Safety and efficiency of SGLT2 inhibitor combining with insulin in subjects with diabetes: Systematic review and meta-analysis of randomized controlled trials: Erratum.

    abstract::[This corrects the article DOI: 10.1097/MD.0000000000006944.]. ...


    pub_type: 已发布勘误



    更新日期:2017-06-30 00:00:00

  • Histogram Analysis of Apparent Diffusion Coefficient in Differentiating Pancreatic Adenocarcinoma and Neuroendocrine Tumor.

    abstract::The aim of this study was to investigate whether histogram analysis in diffusion-weighted (DW) magnetic resonance imaging (MRI) can help differentiate pancreatic adenocarcinomas from neuroendocrine tumors.Sixty-four patients with histologically confirmed 53 pancreatic adenocarcinomas or 19 neuroendocrine tumors underw...


    pub_type: 杂志文章


    authors: Shindo T,Fukukura Y,Umanodan T,Takumi K,Hakamada H,Nakajo M,Umanodan A,Ideue J,Kamimura K,Yoshiura T

    更新日期:2016-01-01 00:00:00

  • Leptin Is Associated With Persistence of Hyperglycemia in Acute Pancreatitis: A Prospective Clinical Study.

    abstract::Adipokines have many homeostatic roles, including modulation of glucose metabolism, but their role in the pathophysiology of hyperglycemia associated with acute and critical illnesses in general, and acute pancreatitis (AP) in particular, is largely unknown. This study aimed to investigate the relationship between a p...


    pub_type: 杂志文章


    authors: Kennedy JIC,Askelund KJ,Premkumar R,Phillips ARJ,Murphy R,Windsor JA,Petrov MS

    更新日期:2016-02-01 00:00:00

  • Invasive bacterial infections in Gambians with sickle cell anemia in an era of widespread pneumococcal and hemophilus influenzae type b vaccination.

    abstract::There is relatively little data on the etiology of bacterial infections in patients with sickle cell anemia (SCA) in West Africa, and no data from countries that have implemented conjugate vaccines against both Streptococcus pneumoniae and Haemophilus influenzae type b (Hib).We conducted a retrospective analysis of SC...


    pub_type: 杂志文章


    authors: Soothill G,Darboe S,Bah G,Bolarinde L,Cunnington A,Anderson ST

    更新日期:2016-12-01 00:00:00

  • Impact of neurological diseases on family planning: A single-center experience.

    abstract::This cross-sectional study aimed to assess the impact of epilepsy, myasthenia gravis (MG), and multiple sclerosis (MS) on pregnancy and family planning decision-making in a cohort of Saudi women. Women with epilepsy, MG, and MS were recruited consecutively at the time of their follow-up visits at a neurology clinic. D...


    pub_type: 杂志文章


    authors: Alanazy MH,Asiri A,Edrees MF,Abuzinadah AR

    更新日期:2020-10-30 00:00:00

  • Comparison of the Degree of Exercise Tolerance in Children After Surgical Treatment of Complex Cardiac Defects, Assessed Using Ergospirometry and the Level of Brain Natriuretic Peptide.

    abstract::Children who underwent surgery for complex congenital heart defects present worse exercise capacity than their healthy peers. In adults and adolescents, heart failure is assessed on the basis of clinical symptoms using the New York Heart Association (NYHA) score, while in an infant Ross scale; heart failure can also b...


    pub_type: 杂志文章


    authors: Mazurek B,Szydlowski L,Mazurek M,Markiewicz-Loskot G,Pajak J,Morka A

    更新日期:2016-02-01 00:00:00

  • Mobile health, physical activity, and obesity: Subanalysis of a randomized controlled trial.

    abstract:BACKGROUND:Recent studies on physical activity were analyzed by randomizing participants into either the intervention or control group. It is necessary to classify each intervention and control groups according to physical activity using the International Physical Activity Questionnaire (IPAQ). METHODS:This was a pilo...


    pub_type: 杂志文章,随机对照试验


    authors: Lee CH,Cheung B,Yi GH,Oh B,Oh YH

    更新日期:2018-09-01 00:00:00

  • Chronic obstructive pulmonary disease is independently associated with hypertension in men: A survey design analysis using nationwide survey data.

    abstract::Although studies have shown that chronic obstructive pulmonary disease (COPD) and hypertension are linked as comorbidities, it remains unclear whether COPD is independently associated with the risk of hypertension or is caused by common risk factors such as age and smoking. The objective of this study was to investiga...


    pub_type: 杂志文章


    authors: Kim SH,Park JH,Lee JK,Heo EY,Kim DK,Chung HS

    更新日期:2017-05-01 00:00:00

  • The association between CCND1 G870A polymorphism and colorectal cancer risk: A meta-analysis.

    abstract:BACKGROUND:CyclinD1 (CCND1) is a key cell cycle regulatory protein. A large number of epidemiological studies have assessed the potential correlation between the CCND1 G870A polymorphism and the risk of colorectal cancer (CRC), but their findings have been inconsistent. To obtain a more precise understanding of the ass...


    pub_type: 杂志文章,meta分析,评审


    authors: Xie M,Zhao F,Zou X,Jin S,Xiong S

    更新日期:2017-10-01 00:00:00

  • Relationship between ABO blood group and risk of venous thrombosis in cancer patients with peripherally inserted central catheters: A protocol for systematic review and meta-analysis.

    abstract:BACKGROUND:Peripherally inserted central catheter (PICC) is closely related to venous thromboembolism (VTE). It is a common complication of hospitalized patients, and its etiology is complex. How to prevent the occurrence of VTE is the focus of clinical work. In order to provide basis for individual prevention and accu...


    pub_type: 杂志文章


    authors: Liu F,Zhang Q,Rao L,Song J

    更新日期:2020-11-06 00:00:00

  • Waist-hip ratio as a predictor of myocardial infarction risk: A systematic review and meta-analysis.

    abstract:BACKGROUND AND AIM:Several studies have identified that obesity and being overweight can increase the risk of developing myocardial infarction (MI). However, the predictive value of the central obesity index, that is, the waist-hip ratio (WHR), regarding MI risk remains unclear. This study aimed to provide a systematic...


    pub_type: 杂志文章,meta分析,评审


    authors: Cao Q,Yu S,Xiong W,Li Y,Li H,Li J,Li F

    更新日期:2018-07-01 00:00:00

  • The Effects of Bevacizumab in Augmenting Trabeculectomy for Glaucoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    abstract::The aim of the study was to assess the effects of bevacizumab in augmenting trabeculectomy for glaucoma. We searched the databases of Cochrane Library, PubMed, Embase, CNKI, and VIP. All the databases were retrieved from the time databases established to September, 2015. The keywords we used were as follows: "bevacizu...


    pub_type: 杂志文章,meta分析,评审


    authors: Liu X,Du L,Li N

    更新日期:2016-04-01 00:00:00

  • Late puerperal hemorrhage of a patient with Klippel-Trenaunay syndrome: A case report.

    abstract:INTRODUCTION:The Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder. The obstetric course of women with KTS varies. Complications include bleeding, disseminated intravascular coagulation (DIC), thromboembolic events, etc. PATIENT CONCERNS:: Here, we report a case of late puerperal hemorrhage of a Chinese pu...


    pub_type: 杂志文章


    authors: Zhang J,Wang K,Mei J

    更新日期:2019-12-01 00:00:00

  • Point prevalence and epidemiological characteristics of chronic cough in the general adult population: The Korean National Health and Nutrition Examination Survey 2010-2012.

    abstract::Cough is frequently self-limiting, but may persist longer in certain individuals. Most of previous studies on the epidemiology of chronic cough have only measured period prevalence, and thus have afforded limited information on the burden and natural course. We aimed to investigate the epidemiology of chronic cough by...


    pub_type: 杂志文章


    authors: Kang MG,Song WJ,Kim HJ,Won HK,Sohn KH,Kang SY,Jo EJ,Kim MH,Kim SH,Kim SH,Park HW,Chang YS,Lee BJ,Morice AH,Cho SH

    更新日期:2017-03-01 00:00:00

  • Ear mold for congenital ear malformation: A randomized controlled trial.

    abstract:BACKGROUND:Congenital auricular deformities (CAD) are prevalent worldwide. The objective of this study is to investigate the effectiveness and safety of ear molding for children with CAD at their early days. METHODS:One hundred and nighty children (under 3 days) with CAD will be included in the study. Participants wil...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Zou K,Fan Y,Jiang L,Huang J,Miao Y,Yang C,Yang M,Zhao L

    更新日期:2020-07-24 00:00:00