Abstract:
:Bisphenol A (BPA) is an environmental endocrine disruptor that has been associated with cardiovascular outcomes in previous observational studies. We aimed to examine the relationships of urinary BPA levels with hypertension and early macrovascular diseases.This is a cross-sectional study. From June through August 2009, 3246 participants ages 40 years or older were enrolled from Baoshan District, Shanghai, China. Logistic regression modes were used to estimate the odds ratios (ORs) for prevalent risk of hypertension, elevated carotid intima-media thickness (CIMT), arterial stiffness, and peripheral artery disease (PAD) with multivariable adjustment. We also performed stratification analysis by age and sex.The median (interquartile range) for BPA was 0.81 (0.48, 1.45) ng/mL, which is notably lower than previously reported in the United States and other Western countries. Urinary BPA concentrations were negatively associated with hypertension (multivariable-adjusted OR for the highest versus lowest BPA quartile = 0.61; 95% confidence interval [CI]: 0.46, 0.80), elevated CIMT (OR = 0.64; 95% CI: 0.47, 0.87), and arterial stiffness (OR = 0.62; 95% CI: 0.44, 0.87). The corresponding OR for PAD (60 cases total) was not significant (OR = 0.89; 95% CI: 0.28, 2.80). The negative associations of BPA with hypertension, elevated CIMT, and arterial stiffness were consistent by age and sex stratifications, and were stronger among participants ≥60 versus <60 years of age, and among women than men.In contrast with previous investigations, our study suggests negative associations of BPA exposure with hypertension and early macrovascular diseases among middle-aged and elderly Chinese. Future investigations are needed to draw more definite conclusions and generalize to other populations.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Wang T,Xu M,Xu Y,Lu J,Li M,Chen Y,Wang W,Lai S,Bi Y,Ning Gdoi
10.1097/MD.0000000000001814subject
Has Abstractpub_date
2015-10-01 00:00:00pages
e1814issue
43eissn
0025-7974issn
1536-5964pii
00005792-201510270-00035journal_volume
94pub_type
杂志文章相关文献
MEDICINE文献大全abstract::We present 2 rare cases of patients with uncontrolled hemorrhagic shock induced by traumatic ascending aortic pseudoaneurysm rupture into the esophagus. Two men were presented to the hospital after traffic accidents. Their chest radiograph showed no obvious signs of aortic damage or aortic pseudoaneurysms but only a s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000716
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Serum pepsinogen assay (sPGA) combining concentration of pepsinogen I (PG I), and the ratio of PG I/II is the noninvasive biomarker for predicting chronic atrophic gastritis (CAG) and neoplasms reflecting mucosal secretory status. Although various cut-off values have been suggested, PG I ≤70 ng/mL and PG I/I...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014240
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:The purpose of a neural integrity monitor electromyogram (EMG) tracheal tube is to reduce the risk of damage to the recurrent laryngeal nerves. Complications associated with the use of EMG tube are ventilatory failure, tracheal injury, and difficult extubation. PATIENT CONCERNS:We encountered a case of di...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020250
更新日期:2020-06-19 00:00:00
abstract::African Americans (AA) with systemic sclerosis (SSc) have a worse prognosis compared to Americans of European descent (EA). We conducted the current study to test the hypothesis that AA patients with SSc have more severe disease and poorer outcomes compared to EA patients when afflicted with pulmonary arterial hyperte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000032
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:With conflicting results in the literature, it remains unclear whether a higher field strength automatically increases the sensitivity and specificity of magnetic resonance imaging (MRI) for detecting pathological lesions in the knee. Therefore, we performed a systematic review and meta-analysis of studies c...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000012401
更新日期:2018-09-01 00:00:00
abstract:RATIONALE:Cervical cancer primarily spreads through direct invasion or via local lymphatics, and hematogenous metastasis is infrequent. Previous reports have shown that lung, liver, and bone are the organs most frequently affected by hematogenous metastasis of cervical cancer, while skeletal muscle is very rarely invol...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000020056
更新日期:2020-05-01 00:00:00
abstract:RATIONALE:Malignant mesenchymoma (MM) is defined as a heterogeneous malignant soft tissue tumor that consists of 2 or more distinctly different mesenchymal components in addition to fibrosarcomatous elements. Bladder MM was rarely reported in the literature and there are only 5 cases of primary bladder MM documented in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007579
更新日期:2017-08-01 00:00:00
abstract::Previous studies have reported that uterine leiomyoma (UL) may share pathogenic features with obesity and hypertension, which are components of metabolic syndrome (MetS). We examined the association between UL and MetS in premenopausal parous women.This 1:1 case-control study was conducted on 615 asymptomatic women wi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005325
更新日期:2016-11-01 00:00:00
abstract::Extra-cardiac abdominal complications are common in left-side infective endocarditis (LS-IE). The aim of this work was to study whether patients with LS-IE presenting splenic, renal, or liver (SRL) involvement seen in abdominal computed tomography (CT) had different clinical features, therapeutic plans, and outcome th...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011952
更新日期:2018-08-01 00:00:00
abstract::Population aging has rapidly advanced throughout the world and the elderly accounting for out-of-hospital cardiac arrest (OHCA) has increased yearly.We identified all adults who experienced an out-of-hospital cardiac arrest in the All-Japan Utstein Registry of the Fire and Disaster Management Agency, a prospective, po...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002049
更新日期:2015-12-01 00:00:00
abstract:INTRODUCTION:Despite the benefits, cardiovascular rehabilitation programs (CRPs) have been related to the appearance of signals and symptoms. Risk stratification protocols are commonly used to identify risks during the physical exercise; however, studies that investigate their efficacy to previse signals and symptoms a...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000015700
更新日期:2019-06-01 00:00:00
abstract::Dysphagia can occur among patients receiving medical care despite having no history of neurologic disease. The current study aimed to investigate factors contributing to airway invasion among non-neurologically ill patients with dysphagia.This retrospective study included 52 non-neurologically ill patients who complai...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000022977
更新日期:2020-11-06 00:00:00
abstract::Idiopathic acute eosinophilic pneumonia (AEP) is an acute febrile illness that may be mistaken for an infectious pneumonia. Patients are often young and otherwise healthy. Clues to considering this disorder in a differential diagnosis include the acuity and severity of the clinical presentation and an initial chest X-...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-199611000-00004
更新日期:1996-11-01 00:00:00
abstract:RATIONALE:ST-segment elevation localizes an ischemic lesion to the coronary artery supplying the area of the myocardium reflected by the electrocardiographic leads. Dynamic ST-segment elevation can be due to severe transmural ischemia secondary to a thrombus, vasospasm, or a tightly fixed coronary artery lesion or a co...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006334
更新日期:2017-03-01 00:00:00
abstract:RATIONALE:Up to one third of all schizophrenic patients are classified as having treatment-resistant schizophrenia (TRS). This subgroup faces remarkable medical and psychosocial damages, and pharmacotherapy is often limited due to nonresponse and/or side effects. Maintenance electroconvulsive therapy (M-ECT) might be e...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008813
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:The number of patients with type 2 diabetes mellitus (T2DM) is surging currently. Synbiotic as a supplement based on gut microbiota may be beneficial to improve the metabolism of T2DM. However, the results of clinical studies show that the role of synbiotic in weight management in patients with T2DM is contr...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000018197
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:DNA methylation is the earliest and most studied epigenetic modification in cancer. The literature reported that the abnormal methylation level of multiple genes was associated with poor prognosis in ovarian cancer. However, due to a small sample size, the results reported in the literature vary widely. In th...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000014588
更新日期:2019-02-01 00:00:00
abstract::To address the reliability of CT activity score (CTAS) and investigate the relationships between CTAS, lung function changes after treatment and the serum angiotensin-converting enzyme (SACE) levels.Fifty-seven sarcoidosis patients underwent chest high-resolution CT (HRCT) and spirometry, as well as SACE examination, ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012205
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Intramedullary cervical spinal cord teratomas (ICTs) are extremely rare, and diagnosis and treatment are challenging. We conducted a systematic review of the literature on the diagnosis and treatment of ICT. METHOD:The presentation, imaging manifestations, diagnosis, management, surgery findings, prognosis ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020107
更新日期:2020-05-01 00:00:00
abstract:RATIONALE:Carcinosarcoma, an extremely rare pancreatic primary tumor, is characterized by coexistence of both carcinomatous and sarcomatous components. Due to its rarity, the clinical manifestation and imaging features have not been recognized. An accurate diagnostic method has not been available and a widely accepted ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000006961
更新日期:2017-06-01 00:00:00
abstract::Lateral talar process fragment excision may be followed by hindfoot instability and altered biomechanics. There is controversy regarding the ideal fragment size for internal fixation versus excision and a concern that excision of a large fragment may lead to significant instability. The aim of this study was to assess...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000606
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Rotavirus infection is the main cause of severe dehydration enteritis in children under 5 years old. It gives rise to malnutrition and even death in children even though there were rotavirus vaccines. However, there is no effective anti-virus drugs for rotavirus, supporting treatments are used in the clinics...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000023376
更新日期:2020-12-04 00:00:00
abstract:BACKGROUND:Intraoperative blood salvage (IBS) recovers most lost blood, and is widely used in the clinic. It is unclear why IBS does not reduce long-term postoperative requirements for red blood cells (RBCs), and 1 possibility is that IBS affects RBC lifespan. METHODS:Prospectively enrolled patients who underwent spin...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008143
更新日期:2017-09-01 00:00:00
abstract:RATIONALE:Acute appendicitis is one of the most common causes of acute abdomen in children, yet it is difficult to diagnose in young children because its clinical manifestations may be atypical. Here, 3 atypical clinical cases associated with appendicitis in children are reported. PATIENT CONCERN:The 1st case correspo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015006
更新日期:2019-03-01 00:00:00
abstract:RATIONALE:Facial cosmetic surgery sometimes causes complications involving surrounding tissues. In particular, parotid damage may cause fibrous tissue formation, ductal stenosis, and obstruct salivary flow. Affected patients usually complain of symptoms such as pain and swelling. PATIENT CONCERNS:The authors report 2 ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015015
更新日期:2019-04-01 00:00:00
abstract::We examined whether the responsiveness to an increase in cigarettes price differed by adolescents' cigarette acquisition source. We analyzed data on 6134 youth smokers (grades 7-12) from a cross-sectional survey in Korea with national representativeness. The respondents were classified into one of the following accord...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007311
更新日期:2017-06-01 00:00:00
abstract:INTRODUCTION:Synchronous colorectal and prostate malignancies are uncommon, with standard treatment guidelines not yet established. Chemoradiation therapy is involved in both colorectal and prostate cancers. However, differing dosage regimens and effects of irradiation field on anatomical planes for surgery makes manag...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020336
更新日期:2020-05-29 00:00:00
abstract:BACKGROUND:Graves ophthalmopathy (GO) is one of the remaining enigmas in thyroidology. Glucocorticoids (GCs) are strongly recommended but their effects are not completely satisfactory and adverse reactions can occur. Tripterygium glycosides (TG) is a promising component extracted from Tripterygium wilfordii Hook F (TwH...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000018242
更新日期:2019-12-01 00:00:00
abstract::The purpose of the present study was to investigate the efficacy and safety of radiotherapy for patients with oligometastases from colorectal cancer (CRC).This was a retrospective cross-sectional study. Patients with liver and/or lung oligometastatic lesions from CRC treated with curative-intent radiotherapy in West C...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012601
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Hysterectomy for benign gynecologic diseases, especially dysfunctional uterine bleeding, is one of the most common gynecologic interventions. The uterus can be removed using abdominal, vaginal, laparoscopic, or robotic-assisted laparoscopic hysterectomy. In a robotic-assisted procedure, the surgeon directs t...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015974
更新日期:2019-06-01 00:00:00