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Successful treatment of a critically ill patient with acute respiratory distress syndrome from COVID-19 using mechanical ventilation strategy with low levels of positive end-expiratory pressure: A CARE-compliant case report.

Abstract：

INTRODUCTION:Acute respiratory distress syndrome (ARDS) secondary to COVID-19 is different from the ARDS caused by other infections. Conventional mechanical ventilation strategies using high levels of PEEP may not be beneficial and can even be harmful to patient with ARDS from COVID-19. So the ventilation strategies should be adjusted in order to improve the pulmonary ventilation function and oxygenation status, and outcomes of the patient. PATIENT CONCERNS:Herein, we present a 76-year-old male patient with ARDS secondary to COVID-19. We describe our experience with mechanical ventilation strategy and the changes in respiratory mechanics in the patient during treatment. DIAGNOSIS:The patient had tested positive for coronavirus (COVID-19) in nucleic acid test. Chest CT showed multiple ground glass shadows in both lungs. INTERVENTIONS:The patient received mechanical ventilation with low tidal volume and low PEEP. OUTCOMES:After treatment, the patients condition, as well as oxygenation status was improved, and he tested negative for the coronavirus several times. CONCLUSION:This case demonstrated that the low tidal volume with low levels of PEEP ventilation strategy may be more suitable for ARDS from COVID-19.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Guo WG,Fang B,Xian YS,Yu ZH,Zhou LX

doi

10.1097/MD.0000000000023160

subject

Has Abstract

pub_date

2020-12-04 00:00:00

pages

e23160

issue

49

eissn

0025-7974

issn

1536-5964

pii

00005792-202012040-00027

journal_volume

99

pub_type

杂志文章

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