Abstract:
:The ability to grow the marine molluse Aplysia under laboratory conditions allows a detailed study of the formation of the nervous system and of the development of specific identified cells. I have found that the ganglia develop in a specific temporal order. Cerebral and pedal ganglia develop at hatching, the abdominal, pleural, and osphradial ganglia 3 weeks after hatching, and the buccal ganglia at 4 weeks. The origin of the abdominal ganglion is complex; its anlage forms at 3 weeks from three larval ganglia that fuse to form the abdominal ganglion. Individual cells cannot be distinguished from one another by their location within the ganglion or by their appearance alone until metamorphosis at 5 weeks. After metamorphosis, the identified neuron, R2, suddenly becomes recognizable because of a significant increase in its size.
journal_name
Proc Natl Acad Sci U S Aauthors
Kriegstein ARdoi
10.1073/pnas.74.1.375subject
Has Abstractpub_date
1977-01-01 00:00:00pages
375-8issue
1eissn
0027-8424issn
1091-6490journal_volume
74pub_type
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