当前位置： SCI文献检索 > ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY期刊下所有文献 > Antioxidant activity of chemically synthesized AgNPs and biosynthesized Pongamia pinnata leaf extract mediated AgNPs - A comparative study.

Antioxidant activity of chemically synthesized AgNPs and biosynthesized Pongamia pinnata leaf extract mediated AgNPs - A comparative study.

Abstract：

:Biosynthesis of metal nanoparticles is the present research in the limb of nanotechnology which reduces the toxicity of metal nanoparticles. Green chemistry approach emphasizes that the usage of plant material has offered a reliable, simple, nontoxic and eco-friendly that links Nanotechnology and Biotechnology. Increasing environmental concerns over chemical synthesis routes have resulted in attempts to develop bio-mimetic approaches. The current study deals with novel method for biosynthesis of AgNPs using Pongamia pinnata leaf extract as reducing agent. These biosynthesized nanoparticles were characterized with the help of UV-vis Spectroscopy, Photoluminescence (PL) and Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Atomic force microscopy (AFM), Dynamic light scattering (DLS) and Zeta Potential (ZP). Free radical scavenging potential of P. pinnata synthesized silver nanoparticles was evaluated in vitro by using five different assays viz., DPPH, ABT+S, Hydroxyl, Superoxide anion and Nitric oxide scavenging assays are also adopted. Capping of AgNPs by various polyphenolic compounds present in P. pinnata leaf extract appears to be a major contributor to lower toxicity compared to chemically synthesized AgNPs. The surface plasmon resonance shows 425nm and grain size of the AgNPs was measured from XRD and FTIR revealed the bioconjucation of AgNPs. The in vitro antioxidant activity of AgNPs showed a significant effect on scavenging of free radicals. The results suggest that the silver nanoparticles from P. pinnata can be potent natural antioxidants and can be essential for health preservation against oxidative stress related degenerative diseases, such as cancer. The vitality of this study lies in the formation of silver nanoparticles by utilizing the wealth of global ecological resources, eliminating obnoxious and toxic reagents which are hazardous to be handled as well as to be applied.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

Priya RS,Geetha D,Ramesh PS

doi

10.1016/j.ecoenv.2015.07.037

subject

Has Abstract

pub_date

2016-12-01 00:00:00

pages

308-318

issue

Pt 2

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(15)30041-5

journal_volume

134

pub_type

杂志文章

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