Abstract：
BACKGROUND:Susceptibility pattern of organisms causing urinary tract infection (UTI) in neonate would potentially improve the clinical management by enabling clinicians to choose most reasonable first line empirical antibiotics. This study aimed to this end by studying isolated organisms from neonates with UTI in an inpatient setting. METHODS:Current retrospective study has recruited all cases of neonatal UTI diagnosed through a suprapubic/catheterized sample, admitted to Neonatal Division of Bahrami Children's Hospital, Tehran, Iran, from June 2004 to June 2012. RESULTS:Escherichia coli was the dominant (64.4%) bacteria among a total of 73 cases (69.9% boys and 30.1% girls; aged 14.14 ± 7.68 days; birth weight of 3055.85 ± 623.00 g) and Enterobacter (19.2%), Klebsiella (12.3%), and Staphylococcus epidermdisis (4.1%) were less frequent isolated bacteria. E. coli was mostly resistant to ampicillin (93.6%), cefixime (85.7%) and cephalexin (77.3%), and sensitive to cefotaxime (63.6%). Enterobacter found to be most resistant to amikacin (100%), ampicillin (92.85%), and most sensitive to ceftizoxime (71.4%). CONCLUSION:A high ratio (> 92.85%) of resistance toward ampicillin was observed among common neonatal UTI bacterial agents. Having this finding along with previous reports of emerging resistance of neonatal uropathogensto ampicillin could be a notion that a combination of a third generation cephalosporin and an aminoglycoside would be a more reasonable first choice than ampicillin plus an aminoglycoside.
journal_name
Iran J Public Healthjournal_title
Iranian journal of public healthauthors
Alizadeh Taheri P,Navabi B,Khatibi Esubject
Has Abstractpub_date
2013-10-01 00:00:00pages
1126-33issue
10eissn
2251-6085issn
2251-6093journal_volume
42pub_type
杂志文章abstract：BACKGROUND:Primary immunodeficiency diseases (PID) are heterogeneous group of inherited disorders mainly characterized by recurrent infections leading to several times hospital admissions. The economic impact of PID is a challenging issue; therefore, this study was designed to determine the medical costs of hospitaliza...
journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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更新日期：2010-01-01 00:00:00
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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journal_title：Iranian journal of public health
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