Abstract:
:Injection of recombinant Cas9 protein and synthetic guide RNAs into mouse zygotes has been shown to facilitate gene disruption and knock-ins using the CRISPR system. These technologies may soon displace genetic modification using embryonic stem cells.
journal_name
Genome Bioljournal_title
Genome biologyauthors
Skarnes WCdoi
10.1186/s13059-015-0673-6subject
Has Abstractpub_date
2015-05-27 00:00:00pages
109eissn
1474-7596issn
1474-760Xpii
10.1186/s13059-015-0673-6journal_volume
16pub_type
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