Unravelling the complex trait of harvest index in rapeseed (Brassica napus L.) with association mapping.

abstract：BACKGROUND:Codon usage analysis has been a classical topic for decades and has significances for studies of evolution, mRNA translation, and new gene discovery, etc. While the codon usage varies among different members of the plant kingdom, indicating the necessity for species-specific study, this work has mostly been ...

journal_title：BMC genomics

authors： Feng C,Xu CJ,Wang Y,Liu WL,Yin XR,Li X,Chen M,Chen KS

更新日期：2013-10-25 00:00:00

abstract：BACKGROUND:Initial interest in Dechloromonas aromatica strain RCB arose from its ability to anaerobically degrade benzene. It is also able to reduce perchlorate and oxidize chlorobenzoate, toluene, and xylene, creating interest in using this organism for bioremediation. Little physiological data has been published for ...

journal_title：BMC genomics

authors： Salinero KK,Keller K,Feil WS,Feil H,Trong S,Di Bartolo G,Lapidus A

更新日期：2009-08-03 00:00:00

abstract：BACKGROUND:Despite recent work to characterize gene expression changes associated with larval development in oysters, the mechanism by which the larval shell is first formed is still largely unknown. In Crassostrea gigas, this shell forms within the first 24 h post fertilization, and it has been demonstrated that chang...

journal_title：BMC genomics

authors： De Wit P,Durland E,Ventura A,Langdon CJ

更新日期：2018-02-22 00:00:00

abstract：BACKGROUND:The increasing numbers of 3D compounds and protein complexes stored in databases contribute greatly to current advances in biotechnology, being employed in several pharmaceutical and industrial applications. However, screening and retrieving appropriate candidates as well as handling false positives presents...

journal_title：BMC genomics

authors： Clinciu DL,Chen YF,Ko CN,Lo CC,Yang JM

更新日期：2010-12-02 00:00:00

abstract：BACKGROUND:The milk fat profile of the Danish Holstein (DH) and Danish Jersey (DJ) show clear differences. Identification of the genomic regions, genes and biological pathways underlying the milk fat biosynthesis will improve the understanding of the biology underlying bovine milk fat production and may provide new pos...

journal_title：BMC genomics

authors： Buitenhuis B,Janss LL,Poulsen NA,Larsen LB,Larsen MK,Sørensen P

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Microarray data analysts commonly filter out genes based on a number of ad hoc criteria prior to any high-level statistical analysis. Such ad hoc approaches could lead to conflicting conclusions with no clear guidance as to which method is most likely to be reproducible. Furthermore, the number of tests perf...

journal_title：BMC genomics

authors： Hu P,Beyene J,Greenwood CM

更新日期：2006-02-22 00:00:00

abstract：BACKGROUND:In animals, signaling of Bone Morphogenetic Proteins (BMPs) is essential for dorsoventral (DV) patterning of the embryo, but how BMP signaling evolved with changes in embryonic DV differentiation is largely unclear. Based on the extensive knowledge of BMP signaling in Drosophila melanogaster, the morphologic...

journal_title：BMC genomics

authors： Lemke S,Antonopoulos DA,Meyer F,Domanus MH,Schmidt-Ott U

更新日期：2011-05-31 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are an abundant class of small single-stranded non-coding RNA molecules ranging from 18 to 24 nucleotides. They negatively regulate gene expression at the post-transcriptional level and play key roles in many biological processes, including skeletal development and cartilage maturation. In...

journal_title：BMC genomics

authors： Desjardin C,Vaiman A,Mata X,Legendre R,Laubier J,Kennedy SP,Laloe D,Barrey E,Jacques C,Cribiu EP,Schibler L

更新日期：2014-09-17 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) post-transcriptionally regulate a variety of genes involved in eukaryotic cell growth, development, metabolism and other biological processes, and numerous miRNAs are implicated in the initiation and progression of cancer. Enzootic nasal adenocarcinoma (ENA), an epithelial tumor induced in...

journal_title：BMC genomics

authors： Wang B,Ye N,Cao SJ,Wen XT,Huang Y,Yan QG

更新日期：2016-11-08 00:00:00

abstract：BACKGROUND:The epithelium is the first line of defense against pathogens. Notably the epithelial cells lining the respiratory track are crucial in sensing airborne microbes and mounting an effective immune response via the expression of target genes such as cytokines and chemokines. Gene expression regulation following...

journal_title：BMC genomics

authors： Borghini L,Hibberd M,Davila S

更新日期：2018-12-27 00:00:00

abstract：BACKGROUND:Bacterial non-coding RNAs act by base-pairing as regulatory elements in crucial biological processes. We performed the identification of trans-encoded small RNAs (sRNA) from the genomes of Mycoplama hyopneumoniae, Mycoplasma flocculare and Mycoplasma hyorhinis, which are Mycoplasma species that have been ide...

journal_title：BMC genomics

authors： Siqueira FM,de Morais GL,Higashi S,Beier LS,Breyer GM,de Sá Godinho CP,Sagot MF,Schrank IS,Zaha A,de Vasconcelos AT

更新日期：2016-10-25 00:00:00

abstract：BACKGROUND:The insect order Neuroptera encompasses more than 5,700 described species. To date, only three neuropteran mitochondrial genomes have been fully and one partly sequenced. Current knowledge on neuropteran mitochondrial genomes is limited, and new data are strongly required. In the present work, the mitochondr...

journal_title：BMC genomics

authors： Negrisolo E,Babbucci M,Patarnello T

更新日期：2011-05-10 00:00:00

abstract：BACKGROUND:We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating the gene encoding a chimeric hexose transporter, Tm6*, into the genome of an hxt null yeast. Subsequently we transferred this respiratory phenotype in the presence of up to 50 g/L glucose to a yeast strai...

journal_title：BMC genomics

authors： Bonander N,Ferndahl C,Mostad P,Wilks MD,Chang C,Showe L,Gustafsson L,Larsson C,Bill RM

更新日期：2008-07-31 00:00:00

abstract：BACKGROUND:The transcription factors peroxisome proliferator activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα) are key transcriptional regulators of adipocyte differentiation and function. We and others have previously shown that binding sites of these two transcription factors show a high degr...

journal_title：BMC genomics

authors： Schmidt SF,Jørgensen M,Chen Y,Nielsen R,Sandelin A,Mandrup S

更新日期：2011-03-16 00:00:00

abstract：BACKGROUND:Infectious salmon anemia virus (ISAV) causes a multisystemic disease responsible for severe losses in salmon aquaculture. Better understanding of factors that explain variations in resistance between individuals and families is essential for development of strategies for disease control. To approach this, we...

journal_title：BMC genomics

authors： Jørgensen SM,Afanasyev S,Krasnov A

更新日期：2008-04-18 00:00:00

abstract：BACKGROUND:Lysophosphatidic acid (LPA) is a lipid mediator that acts through specific G protein-coupled receptors to stimulate the proliferation, migration and survival of many cell types. LPA signaling has been implicated in development, wound healing and cancer. While LPA signaling pathways have been studied extensiv...

journal_title：BMC genomics

authors： Stortelers C,Kerkhoven R,Moolenaar WH

更新日期：2008-08-14 00:00:00

abstract：BACKGROUND:Precision medicine is a medical approach that takes into account individual genetic variability and often requires Next Generation Sequencing data in order to predict new treatments. Here we present GMIEC, Genomic Modules Identification et Characterization for genomics medicine, an application that is able t...

journal_title：BMC genomics

authors： Malagoli Tagliazucchi G,Taccioli C

更新日期：2020-09-10 00:00:00

abstract：BACKGROUND:Very little is known about the immunological responses of amphibians to pathogens that are causing global population declines. We used a custom microarray gene chip to characterize gene expression responses of axolotls (Ambystoma mexicanum) to an emerging viral pathogen, Ambystoma tigrinum virus (ATV). RESU...

journal_title：BMC genomics

authors： Cotter JD,Storfer A,Page RB,Beachy CK,Voss SR

更新日期：2008-10-20 00:00:00

abstract：BACKGROUND:The accurate determination of the genomic coordinates for a given gene - its gene model - is of vital importance to the utility of its annotation, and the accuracy of bioinformatic analyses derived from it. Currently-available methods of computational gene prediction, while on the whole successful, frequentl...

journal_title：BMC genomics

authors： Dunne MP,Kelly S

更新日期：2018-04-27 00:00:00

abstract：BACKGROUND:Fruit peel colour is an important agronomic trait for fruit quality. Cytosine methylation plays an important role in gene regulation. Although the DNA methylation level of a single gene is important to affect the phenotype of mutation, there are large unknown of difference of the DNA methylation in plant and...

journal_title：BMC genomics

authors： Jiang SH,Sun QG,Chen M,Wang N,Xu HF,Fang HC,Wang YC,Zhang ZY,Chen XS

更新日期：2019-02-07 00:00:00

abstract：BACKGROUND:Laboratory evolution is an important tool for developing robust yeast strains for bioethanol production since the biological basis behind combined tolerance requires complex alterations whose proper regulation is difficult to achieve by rational metabolic engineering. Previously, we reported on the evolved i...

journal_title：BMC genomics

authors： Wallace-Salinas V,Brink DP,Ahrén D,Gorwa-Grauslund MF

更新日期：2015-07-09 00:00:00

abstract：BACKGROUND:Soybean cyst nematode (SCN) is the most economically devastating pathogen of soybean. Two resistance loci, Rhg1 and Rhg4 primarily contribute resistance to SCN race 3 in soybean. Peking and PI 88788 are the two major sources of SCN resistance with Peking requiring both Rhg1 and Rhg4 alleles and PI 88788 only...

journal_title：BMC genomics

authors： Shi Z,Liu S,Noe J,Arelli P,Meksem K,Li Z

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:Controlling gene expression is fundamental to biological complexity. The nematode Caenorhabditis elegans is an important model for studying principles of gene regulation in multi-cellular organisms. A comprehensive parts list of putative regulatory motifs was yet missing for this model system. In this study,...

journal_title：BMC genomics

authors： Dieterich C,Sommer RJ

更新日期：2008-01-23 00:00:00

abstract：BACKGROUND:Although profiling of RNA in single cells has broadened our understanding of development, cancer biology and mechanisms of disease dissemination, it requires the development of reliable and flexible methods. Here we demonstrate that the EpiStem RNA-Amp™ methodology reproducibly generates microgram amounts of...

journal_title：BMC genomics

authors： Rothwell DG,Li Y,Ayub M,Tate C,Newton G,Hey Y,Carter L,Faulkner S,Moro M,Pepper S,Miller C,Blackhall F,Bertolini G,Roz L,Dive C,Brady G

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Tandem repeats are ubiquitous and abundant in higher eukaryotic genomes and constitute, along with transposable elements, much of DNA underlying centromeres and other heterochromatic domains. In maize, centromeric satellite repeat (CentC) and centromeric retrotransposons (CR), a class of Ty3/gypsy retrotrans...

journal_title：BMC genomics

authors： Sharma A,Wolfgruber TK,Presting GG

更新日期：2013-03-04 00:00:00

abstract：:Following the publication of the original article [1], the authors reported an error in Fig. 2 of the PDF version of their article. ...

journal_title：BMC genomics

authors： Maarsingh JD,Yang S,Park JG,Haydel SE

更新日期：2019-12-31 00:00:00

abstract：BACKGROUND:Transcriptome expression analysis in peanut to date has been limited to a relatively small set of genes and only recently has a significant number of ESTs been released into the public domain. Utilization of these ESTs for oligonucleotide microarrays provides a means to investigate large-scale transcript res...

journal_title：BMC genomics

authors： Payton P,Kottapalli KR,Rowland D,Faircloth W,Guo B,Burow M,Puppala N,Gallo M

更新日期：2009-06-12 00:00:00

abstract：BACKGROUND:Brown and white adipose tissues (BAT and WAT) play critical roles in controlling energy homeostasis and in the development of obesity and diabetes. The mouse Fat-Specific protein 27 (FSP27), a member of the cell death-inducing DFF45-like effector (CIDE) family, is expressed in both BAT and WAT and is associa...

journal_title：BMC genomics

authors： Li D,Zhang Y,Xu L,Zhou L,Wang Y,Xue B,Wen Z,Li P,Sang J

更新日期：2010-07-22 00:00:00

abstract：BACKGROUND:The complex genome of rapeseed (Brassica napus) is not well understood despite the economic importance of the species. Good knowledge of sequence variation is needed for genetics approaches and breeding purposes. We used a diversity set of B. napus representing eight different germplasm types to sequence gen...

journal_title：BMC genomics

authors： Bus A,Hecht J,Huettel B,Reinhardt R,Stich B

更新日期：2012-06-24 00:00:00

abstract：BACKGROUND:Tumor necrosis factor alpha (TNF) is able to induce a variety of biological responses in the nervous system including inflammation and neuroprotection. Human astrocytoma cells U373 have been widely used as a model for inflammatory cytokine actions in the nervous system. Here we used cDNA microarrays to analy...

journal_title：BMC genomics

authors： Schwamborn J,Lindecke A,Elvers M,Horejschi V,Kerick M,Rafigh M,Pfeiffer J,Prüllage M,Kaltschmidt B,Kaltschmidt C

更新日期：2003-11-25 00:00:00