Abstract:
BACKGROUND:Although donation after cardiac death (DCD) liver allografts have been used to expand the donor pool, concerns exist regarding primary nonfunction and biliary complications. Our aim was to compare resource use and outcomes of DCD allografts with donation after brain death (DBD) liver allografts. STUDY DESIGN:Using a linkage between the University HealthSystem Consortium and Scientific Registry of Transplant Recipients databases, we identified 11,856 patients who underwent deceased donor liver transplantation (LT) from 2007 to 2011. Patients were divided into 2 cohorts based on type of allograft (DCD vs DBD). Matched pair analysis (n = 613 in each group) was used to compare outcomes of the 2 donor types. RESULTS:Donation after cardiac death allografts comprised 5.2% (n = 613) of all LTs in the studied cohort; DCD allograft recipients were healthier and had lower median Model of End-Stage Liver Disease (MELD) score (17 vs 19; p < 0.0001). Post LT, there was no significant difference in length of stay, perioperative mortality, and discharge to home rates. However, DCD allografts were associated with higher direct cost ($110,414 vs $99,543; p < 0.0001) and 30-day readmission rates (46.4% vs 37.1%; p < 0.0001). Matched analysis revealed that DCD allografts were associated with higher direct cost, readmission rates, and inferior graft survival. CONCLUSIONS:While confirming the previous reports of inferior graft survival associated with DCD allografts, this is the first national report to show increased financial and resource use associated with DCD compared with DBD allografts in a matched recipient cohort.
journal_name
J Am Coll Surgjournal_title
Journal of the American College of Surgeonsauthors
Singhal A,Wima K,Hoehn RS,Quillin RC 3rd,Woodle ES,Paquette IM,Paterno F,Abbott DE,Shah SAdoi
10.1016/j.jamcollsurg.2015.01.052subject
Has Abstractpub_date
2015-05-01 00:00:00pages
951-8issue
5eissn
1072-7515issn
1879-1190pii
S1072-7515(15)00115-5journal_volume
220pub_type
杂志文章abstract:BACKGROUND:With the general acceptance of lumpectomy, axillary staging, and radiotherapy as local treatment for infiltrating breast cancer, an appreciation is evolving for the spectrum of vascular lesions that occur in the mammary skin after this treatment. Most of these lesions develop within the prior radiation field...
journal_title:Journal of the American College of Surgeons
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doi:10.1016/s1072-7515(01)00863-8
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abstract:BACKGROUND:The concomitant use of nonabsorbable mesh during stapled bariatric surgery has been discouraged due to potential contamination. The aim of our study was to compare and quantify the extent of bacterial load and gross contamination of the peritoneal cavity in patients undergoing laparoscopic sleeve gastrectomy...
journal_title:Journal of the American College of Surgeons
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journal_title:Journal of the American College of Surgeons
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abstract:BACKGROUND:Academic divisions of general surgery are facing ever-increasing financial pressures. Cost-cutting is a common approach to maintaining profitability, but strategies to increase revenue should not be ignored. One specific avenue for enhanced revenue generation in general surgery is that of coding for evaluati...
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abstract:BACKGROUND:Colorectal surgery may lead to infections because despite meticulous aseptic measures, extravasation of microorganisms from the colon lumen is unavoidable. STUDY DESIGN:A prospective, randomized study was performed between January 2010 and December 2010. Patient inclusion criteria were a diagnosis of colore...
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更新日期:2014-02-01 00:00:00
abstract::Limited resection can be a therapeutic approach in patients with cirrhosis with very low remnant hepatic function after resection. In this study, two hilar vascular clamping methods (hilar selective clamping [n = 13] and hilar lobar clamping method [n = 8]), which were used for resection of hepatocellular carcinoma in...
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更新日期:2015-08-01 00:00:00
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journal_title:Journal of the American College of Surgeons
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