[Hereditary spherocytosis. Review. Part II. Symptomatology, outcome, complications, and treatment].

Abstract:

:Hereditary spherocytosis must always be suspected in children with anemia, hyperbilirubinemia, splenomegaly or cholelithiasis, in the asymptomatic individual with an affected relative, and in the neonate with hyperbilirubinemia with no blood group incompatibility; its early detection is key to avoid kernicterus. Follow-up of these patients is based on periodical control and supply of information on the adequate management of hemolytic or aplastic crisis, and early detection of cholelithiasis. The decision to perform splenectomy is usually associated with quality of life rather than life-threatening risk, and it should result from a consensus between patient, parents and physicians. The postsplenectomy follow-up is based on control of compliance with the prophylactic antibiotic therapy and the early diagnosis of infectious disorders.

journal_name

Arch Argent Pediatr

authors

Comité Nacional de Hematología.,Donato H,Crisp RL,Rapetti MC,García E,Attie M

doi

10.5546/aap.2015.168

subject

Has Abstract

pub_date

2015-04-01 00:00:00

pages

168-76

issue

2

eissn

0325-0075

issn

1668-3501

pii

S0325-00752015000200025

journal_volume

113

pub_type

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