Abstract：
:This article questions the scientific justification of ingrained radiologic practices exemplified by size measurements of childhood solid tumours. This is approached by a critical review of staging systems from a selection of paediatric oncological treatment protocols. Local staging remains size-dependent for some tumour types. The consequent stage assignment can significantly influence treatment intensity. Still, the protocols tend not to give precise guidance on how to perform scans and standardise measurements. Also, they do not estimate or account for the inevitable variability in measurements. Counts and measurements of lung nodules are, within some tumour groups, used for diagnosis of metastatic disease. There is, however, no evidence that nodule size is a useful discriminator of benign and malignant lung nodules. The efficacy of imaging depends chiefly on observations being precise, accurate and valid for the desired diagnostic purpose. Because measurements without estimates of their errors are meaningless, studies of variability dependent on tumour shape and location, imaging device and observer need to be encouraged. Reproducible observations make good candidates for staging parameters if they have prognostic validity and at the same time show little covariation with (thereby adding new information to) the existing staging system. The lack of scientific rigour has made the validity of size measurement very difficult to assess. Action is needed, the most important being radiologists' active contribution in development of oncological staging systems, attention to standardisation, knowledge about errors in measurement and protection against undue influence of such errors in the staging of the individual child.
journal_name
Pediatr Radioljournal_title
Pediatric radiologyauthors
Olsen ØEdoi
10.1007/s00247-014-3148-0subject
Has Abstractpub_date
2015-01-01 00:00:00pages
35-41issue
1eissn
0301-0449issn
1432-1998journal_volume
45pub_type
杂志文章,评审abstract：:Parameters of linear measurement were compared with actual brain volume to assess the significance of linear measurements as indices of atrophy in 31 neurologically normal children and 22 neurologically abnormal children. Brain volume was established by means of an image-analyzing system using contiguous CT scans. The...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02013822
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Neurosonography can assist clinicians and can provide researchers with documentation of brain lesions. Unfortunately, we know little about the reliability of sonographically derived diagnoses. OBJECTIVE:We sought to evaluate observer variability among experienced neurosonologists. MATERIALS AND METHODS:We ...
journal_title：Pediatric radiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00247-007-0605-z
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:Pyeloplasty is an established treatment for pelviureteric junction (PUJ) obstruction. The postoperative change in the size of the renal pelvis and the kidney parenchyma are variable. OBJECTIVE:To document the changes in renal pelvic size and renal parenchymal thickness following pyeloplasty and to establish...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470050342
更新日期：1998-04-01 00:00:00
abstract：:The original version of this paper included errors in Fig. 3. The corrected Fig. 3 is presented here. ...
journal_title：Pediatric radiology
pub_type： 已发布勘误
doi：10.1007/s00247-020-04665-6
更新日期：2020-05-01 00:00:00
abstract：:Up to now, the presence of elevated intracranial pressure (ICP) in acute neurological disorders is suspected by clinical and neuroimaging findings, but its verification depends on invasive techniques. Based on our experimental findings of rapid dilatation of human optic nerve sheaths (ONS), we investigated whether thi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01383384
更新日期：1996-10-01 00:00:00
abstract：:Sonographic examination of the adrenal glands of three newborns with congenital adrenal hyperplasia demonstrated a cerebriform pattern. This is introduced as a sonographic feature specific to the disease. This finding in patients with ambiguous genitalia should suggest the diagnosis even if the adrenals are not signif...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02012391
更新日期：1993-01-01 00:00:00
abstract：:Purpose. To determine whether gadolinium-enhanced MR imaging can detect early reversible ischemia of the capital femoral epiphysis and physis induced by hip hyperabduction in piglets. Materials and methods. Thirteen 1- to 3-week-old piglets were placed in maximal abduction of both hips and studied with dynamic gadolin...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02011824
更新日期：1995-01-01 00:00:00
abstract：:This article is the first of a two-part series on intracranial calcification in childhood. Intracranial calcification can be either physiological or pathological. Physiological intracranial calcification is not an expected neuroimaging finding in the neonatal or infantile period but occurs, as children grow older, in ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-020-04721-1
更新日期：2020-09-01 00:00:00
abstract：:Chylopericardium rarely occurs in pediatric patients, but when it does it is most often a result of lymphatic injury during cardiothoracic surgery. Primary idiopathic chylopericardium is especially rare, with few cases in the pediatric literature. We report a 10-year-old boy who presented with primary idiopathic chylo...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-014-3182-y
更新日期：2015-06-01 00:00:00
abstract：:Intravesical catheter knotting during micturating cystourethrography is a rare but recognized complication of the procedure. We were able to untangle a knot utilizing a fluoroscopically guided vascular guidewire. Following this success, a small study was performed using a model. Various types of guidewires and techniq...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-007-0426-0
更新日期：2007-04-01 00:00:00
abstract：:Peutz-Jeghers syndrome (PJS) is a rare, though well-described, hereditary polyposis syndrome associated with mucocutaneous pigmentation that typically presents in the second decade of life with complications related to intestinal polyps. We present two cases of teenaged girls presenting with small-bowel intussusceptio...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-002-0695-6
更新日期：2002-09-01 00:00:00
abstract：:We present a pictorial review of neonatal ischemic brain injury and look at its pathophysiology, imaging features and differential diagnoses from a radiologist's perspective. The concept of perinatal stroke is defined and its distinction from hypoxic-ischemic injury is emphasized. A brief review of recent imaging adva...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-011-2332-8
更新日期：2012-05-01 00:00:00
abstract：:The clinical value of computerized body tomography (CT) was analysed in 221 consecutive examinations performed in the evaluation and surveillance of 74 children with various types of extracranial solid malignant tumours. CT was performed as part of a routine diagnostic reassessment in 104 cases and was clinically indi...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00999310
更新日期：1982-01-01 00:00:00
abstract：:We review the clinical and imaging characteristics of the most common ovarian neoplasms in children and adolescents. Because of the widespread use of diagnostic imaging, incidental ovarian neoplasms might be encountered during the evaluation of abdominal pain, trauma or other indications and might pose a diagnostic di...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-011-2128-x
更新日期：2011-09-01 00:00:00
abstract：:The aim of this review is to emphasize the role of fetal MR in the evaluation of the supratentorial space. The advantages of MRI compared to US are stressed in three fields of application: cerebral biometry, sulcation and cerebral parenchyma. In each field, normal data are displayed and MR applications with patterns o...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-004-1249-x
更新日期：2004-09-01 00:00:00
abstract：:The anatomical anomalies that characterize septo-optic-dysplasia (deMorsier Syndrome) are variable and often subtle. We report imaging studies of nine patients with septo-optic-dysplasia which provide radiologic and ultrasonographic clues to this disorder. In addition, we propose that cerebral schizencephaly may be a ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02388642
更新日期：1989-01-01 00:00:00
abstract：:Multiple epiphyseal dysplasia (MED) is an osteochondrodysplasia characterized clinically by mild short stature and early-onset degenerative joint disease and radiographically by epiphyseal hypoplasia/dysplasia. MED is genetically heterogeneous, with autosomal dominant cases resulting from mutations in at least three g...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s002470000362
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND:Inferior vena cava (IVC) filter placement in children has been described in literature, but there is variability with regard to their indications. No nationally representative study has been done to compare practice patterns of filter placements at adult and children's hospitals. OBJECTIVE:To perform a nati...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-017-4001-z
更新日期：2018-02-01 00:00:00
abstract：:Alongside recent advances in treatment strategies for juvenile idiopathic arthritis (JIA), paediatric rheumatologists have taken increasing interest in the use of imaging. Magnetic resonance imaging (MRI) and musculoskeletal ultrasound, by providing more detailed information on disease activity than clinical examinati...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-017-4014-7
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Glutaric aciduria type 1 is a rare neurometabolic disease with high morbidity. OBJECTIVE:To describe the MR imaging abnormalities in glutaric aciduria type 1 and to identify any association between the clinical and imaging features. MATERIALS AND METHODS:MRI scans of 29 children (mean age: 16.9 months) wit...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-015-3395-8
更新日期：2015-10-01 00:00:00
abstract：:Colour Doppler sonography is of value in diagnosing scrotal pathology. We report a case of testicular torsion misdiagnosed as a paratesticular tumour by colour Doppler sonography and highlight some of the pitfalls involved in this technique. ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02012461
更新日期：1993-01-01 00:00:00
abstract：: ...
journal_title：Pediatric radiology
pub_type： 评论,杂志文章
doi：10.1007/s00247-018-4248-z
更新日期：2018-11-01 00:00:00
abstract：:Radiographic examinations of the paranasal sinuses and chests of 187 patients with C.F. from five months to 27 years of age were reviewed. One hundred eight-five patients consistently had opaque maxillary and ethmoidal sinuses. Forty-five patients had normal chest radiographs. These observations show that the paranasa...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF00977665
更新日期：1980-02-01 00:00:00
abstract：:Loss of bowel gas was observed in 18 out of 49 neonates on mechanical ventilation (37%). Its occurrence was correlated to the outcome and to the use of sedative or neuromuscular paralysing drugs. None of the babies had gastrointestinal disorders requiring surgical intervention. A gasless abdomen was found in 6 our of ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01221704
更新日期：1982-01-01 00:00:00
abstract：:Primary vesicoureteral reflux (VUR) is thought to be largely independent of obstruction. Therefore, in patients with urethral obstruction due to posterior urethral valves (PUV) the occurrence of VUR is coincidental. In addition, primary VUR is reported to be uncommon in black children. If these two premises are correc...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02388405
更新日期：1988-01-01 00:00:00
abstract：BACKGROUND:MRI is the most sensitive imaging modality in juvenile idiopathic arthritis (JIA), but has practical limitations. Optimizing the scanning protocol is, therefore, necessary to increase feasibility and patient comfort. OBJECTIVE:To determine the feasibility of bilateral non-contrast-enhanced open-bore MRI of ...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/s00247-011-2306-x
更新日期：2012-04-01 00:00:00
abstract：PURPOSE:This prospective study was designed to determine the effect of patient positioning on sonographic measurements of renal length in children. Materials and methods. Two dedicated pediatric ultrasonographers (observers A and B) measured the sonographic lengths of 48 kidneys in 25 children (two had unilateral renal...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF01372240
更新日期：1996-01-01 00:00:00
abstract：:Imaging pediatric elbow trauma in the acute setting remains diagnostically challenging given difficult patient positioning, multiple ossification centers of the pediatric elbow, overlapping structures, and complex joint anatomy. Digital tomosynthesis is a technique where the X-ray source travels across a limited arc a...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-019-04444-y
更新日期：2019-11-01 00:00:00
abstract：:Paternal uniparental disomy for chromosome 14 (patUPD14) is a rare condition, this being the eighth report. A male infant, born prematurely, was noted to have extremely lax skin and bilateral inguinal hernias. Skin biopsy confirmed the clinical diagnosis of congenital cutis laxa, but this did not explain the limb abno...
journal_title：Pediatric radiology
pub_type： 杂志文章,评审
doi：10.1007/s00247-003-0931-8
更新日期：2003-07-01 00:00:00
abstract：:Anomalous origin of the left pulmonary artery in tetralogy of Fallot was diagnosed in a 4-year-old boy be cardiac catheterization. Corrective surgery was performed. The child died immediately following the surgical procedure. Postmortem examination revealed obstructive pulmonary vascular disease of the left lung and n...
journal_title：Pediatric radiology
pub_type： 杂志文章
doi：10.1007/BF02388368
更新日期：1985-01-01 00:00:00
