Temporary organ substitution by hemoperfusion through suspension of active donor hepatocytes in a total complex of intensive therapy in patients with acute hepatic insufficiency.

Abstract:

:The results of intensive therapy and temporary organ substitution by hemoperfusion through a suspension of active hepatocytes in 126 patients suffering from acute hepatic insufficiency (AHI) induced by virus B hepatitis, virus non-A, non-B hepatitis, acute toxic hepatitis, active liver cirrhosis, sepsis leptospirosis long-term subhepatic jaundice are presented in this paper. Hepatic encephalopathia confirmed both clinically and electroencephalographically was registered in all the patients. The patients were subdivided into two groups: a complex of commonly used curative measures according to the intensive therapy for AHI was applied in Group A (67 patients); in Group B (59 patients), alongside with the above measures, temporary organ substitution by hemoperfusion through a suspension of active porky hepatocytes was also performed. The lethality in Group A made up 59% and that in Group B was 37%.

journal_name

Resuscitation

journal_title

Resuscitation

authors

Margulis MS,Erukhimov EA,Andreiman LA,Viksna LM

doi

10.1016/0300-9572(89)90115-9

subject

Has Abstract

pub_date

1989-10-01 00:00:00

pages

85-94

issue

1

eissn

0300-9572

issn

1873-1570

pii

0300-9572(89)90115-9

journal_volume

18

pub_type

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