Early management of patients with acute heart failure: state of the art and future directions. A consensus document from the society for academic emergency medicine/heart failure society of America acute heart failure working group.

Abstract:

:Heart failure (HF) afflicts nearly 6 million Americans, resulting in one million emergency department (ED) visits and over one million annual hospital discharges. An aging population and improved survival from cardiovascular diseases is expected to further increase HF prevalence. Emergency providers play a significant role in the management of patients with acute heart failure (AHF). It is crucial that emergency physicians and other providers involved in early management understand the latest developments in diagnostic testing, therapeutics and alternatives to hospitalization. Further, clinical trials must be conducted in the ED in order to improve the evidence base and drive optimal initial therapy for AHF. Should ongoing and future studies suggest early phenotype-driven therapy improves in-hospital and post-discharge outcomes, ED treatment decisions will need to evolve accordingly. The potential impact of future studies which incorporate risk-stratification into ED disposition decisions cannot be underestimated. Predictive instruments that identify a cohort of patients safe for ED discharge, while simultaneously addressing barriers to successful outpatient management, have the potential to significantly impact quality of life and resource expenditures.

journal_name

J Card Fail

authors

Collins S,Storrow AB,Albert NM,Butler J,Ezekowitz J,Felker GM,Fermann GJ,Fonarow GC,Givertz MM,Hiestand B,Hollander JE,Lanfear DE,Levy PD,Pang PS,Peacock WF,Sawyer DB,Teerlink JR,Lenihan DJ,SAEM\/HFSA Acute Heart Fail

doi

10.1016/j.cardfail.2014.07.003

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

27-43

issue

1

eissn

1071-9164

issn

1532-8414

pii

S1071-9164(14)00676-9

journal_volume

21

pub_type

杂志文章,评审
  • Aldosterone stimulates angiotensin-converting enzyme expression and activity in rat neonatal cardiac myocytes.

    abstract:BACKGROUND:Members of the nuclear receptor family proteins function as transcription factors upon ligand binding and thereby regulate gene expression in host cells. Aldosterone, the high-affinity endogenous ligand for the mineralocorticoid receptor, induces cardiac hypertrophy and fibrosis in a variety of animal models...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2002.125369

    authors: Wang J,Yu L,Solenberg PJ,Gelbert L,Geringer CD,Steinberg MI

    更新日期:2002-06-01 00:00:00

  • Dual Vasopressin V1a/V2 Antagonism: The Next Step in Neurohormonal Modulation in Patients With Heart Failure?

    abstract::Stimulation of the V1a receptor for arginine vasopressin produces myocardial and vascular effects similar to those of angiotensin II while stimulation of the V2 receptor causes fluid retention. There are no data with sustained blockade of the V1a receptor while single-dose experiments suggest benefit. Acute and chroni...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,评审

    doi:10.1016/j.cardfail.2017.12.011

    authors: Goldsmith SR,Udelson JE,Gheorghiade M

    更新日期:2018-02-01 00:00:00

  • Proposal for a new clinical end point to evaluate the efficacy of drugs and devices in the treatment of chronic heart failure.

    abstract::Clinical trials designed to evaluate the effect of drugs and devices on the symptoms and clinical status in chronic heart failure have frequently produced conflicting, inconclusive, or misleading results. These difficulties can be explained by the fact that previous studies have relied on efficacy measures that have i...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2001.25652

    authors: Packer M

    更新日期:2001-06-01 00:00:00

  • HFSA 2006 Comprehensive Heart Failure Practice Guideline.

    abstract::Heart failure (HF) is a syndrome characterized by high mortality, frequent hospitalization, reduced quality of life, and a complex therapeutic regimen. Knowledge about HF is accumulating so rapidly that individual clinicians may be unable to readily and adequately synthesize new information into effective strategies o...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.cardfail.2005.11.005

    authors: Heart Failure Society Of America

    更新日期:2006-02-01 00:00:00

  • Acute Unloading Effects of Sildenafil Enhance Right Ventricular-Pulmonary Artery Coupling in Heart Failure.

    abstract:BACKGROUND:Phosphodiesterase-5A inhibitors (PDE5i) are sometimes used in patients with advanced heart failure with reduced ejection fraction before heart transplant or left ventricular assist device implantation to decrease right ventricular (RV) afterload and mitigate the risk of right heart failure. Conflicting evide...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2020.11.007

    authors: Monzo L,Reichenbach A,Al-Hiti H,Borlaug BA,Havlenova T,Solar N,Tupy M,Ters J,Kautzner J,Melenovsky V

    更新日期:2020-11-21 00:00:00

  • The relationship between anemia, change in hematocrit over time and change in health status in patients with heart failure after myocardial infarction.

    abstract:BACKGROUND:Studies have identified anemia as a potential therapeutic target in patients with heart failure, with the goal of improving survival and health status. However, whether changes in hematocrit are associated with changes in health status is unknown. METHODS AND RESULTS:We studied 1382 patients with heart fail...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2007.09.009

    authors: Kosiborod M,Krumholz HM,Jones PG,Pitt B,Spertus JA

    更新日期:2008-02-01 00:00:00

  • Body mass and survival in patients with chronic heart failure without cachexia: the importance of obesity.

    abstract:BACKGROUND:Cachexia in chronic heart failure carries a poor prognosis, but little is known about the influence of body mass on the prognosis of noncachectic heart failure patients. METHODS:We studied 589 consecutive chronic heart failure patients followed for at least a year, in whom there were accurate baseline data ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2003.4

    authors: Davos CH,Doehner W,Rauchhaus M,Cicoira M,Francis DP,Coats AJ,Clark AL,Anker SD

    更新日期:2003-02-01 00:00:00

  • Relationship between anemia and health care costs in heart failure.

    abstract:BACKGROUND:Anemia is associated with higher morbidity and mortality in patients with heart failure (HF), but its implications for heath care costs are not well described. METHODS AND RESULTS:We analyzed data on 1056 patients with symptomatic HF seen at Duke University between 2002 and 2006. Health care costs were obta...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2009.06.435

    authors: Allen LA,Anstrom KJ,Horton JR,Shaw LK,Eisenstein EL,Felker GM

    更新日期:2009-12-01 00:00:00

  • Comparing Perspectives of Patients, Caregivers, and Clinicians on Heart Failure Management.

    abstract:BACKGROUND:Although substantial effort has been devoted to reducing readmissions among heart failure (HF) patients, little is known about factors identified by patients and caregivers that may contribute to readmissions. The goal of this study was to compare the perspectives of HF patients, their caregivers, and their ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2015.10.011

    authors: Ahmad FS,Barg FK,Bowles KH,Alexander M,Goldberg LR,French B,Kangovi S,Gallagher TR,Paciotti B,Kimmel SE

    更新日期:2016-03-01 00:00:00

  • Quality of care and hospital readmission in congestive heart failure: an explicit review process.

    abstract:BACKGROUND:The effect of hospital quality of care on hospital readmission for patients with congestive heart failure (CHF) has not been widely studied. METHODS AND RESULTS:We examined the effects of clinical factors, hospital quality of care, and cardiologist involvement on 3-month readmission rates in patients with C...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2001.28931

    authors: Polanczyk CA,Newton C,Dec GW,Di Salvo TG

    更新日期:2001-12-01 00:00:00

  • How does cardiac resynchronization therapy improve exercise capacity in chronic heart failure?

    abstract:BACKGROUND:Studies have shown that neither ejection fraction nor hemodynamic abnormalities during exercise in chronic heart failure (HF) correlate with symptoms of fatigue and exhaustion. The concept that exercise limitation in patients with chronic HF is due to abnormal hemodynamics during exercise has been revised to...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,评审

    doi:10.1016/j.cardfail.2005.03.002

    authors: Middlekauff HR

    更新日期:2005-09-01 00:00:00

  • Effects of lisinopril in patients with heart failure and chronic atrial fibrillation.

    abstract::Although atrial fibrillation is common in patients with heart failure, patients with atrial fibrillation are often excluded from congestive heart failure trials or are not analyzed separately. Consequently, while the effect of angiotensin-converting enzyme inhibitors in patients with sinus rhythm is well established, ...

    journal_title:Journal of cardiac failure

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s1071-9164(05)80004-1

    authors: Van Den Berg MP,Crijns HJ,Van Veldhuisen DJ,Griep N,De Kam PJ,Lie KI

    更新日期:1995-12-01 00:00:00

  • Effect of cardiac resynchronization therapy on left ventricular diastolic function: implications for clinical outcome.

    abstract:BACKGROUND:The definition of response to cardiac resynchronization therapy (CRT) remains controversial, with variable rates of response depending on the criteria used. Our aim was to analyze the impact of CRT on diastolic function in different degrees of response, particularly in patients with positive clinical but no ...

    journal_title:Journal of cardiac failure

    pub_type: 更正并重新发布的文章,杂志文章

    doi:10.1016/j.cardfail.2013.11.001

    authors: Doltra A,Bijnens B,Tolosana JM,Gabrielli L,Castel MÁ,Berruezo A,Brugada J,Mont L,Sitges M

    更新日期:2013-12-01 00:00:00

  • Pharmacotherapy Use in Older Patients With Heart Failure and Reduced Ejection Fraction After a Skilled Nursing Facility Stay.

    abstract:BACKGROUND:Little is known about guideline-directed pharmacotherapy use in patients with heart failure and reduced ejection fraction (HFrEF) discharged to skilled nursing facilities (SNFs). This study aimed to describe the use of angiotensin-converting enzyme inhibitors (ACEIs)/angiotensin receptor blocker (ARBs) and e...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2017.09.007

    authors: Li L,Jesdale BM,Hume A,Gambassi G,Goldberg RJ,Lapane KL

    更新日期:2017-12-01 00:00:00

  • Activities and Compensation of Advanced Heart Failure Specialists: Results of the Heart Failure Society of America (HFSA) Survey.

    abstract:BACKGROUND:In the current era, where advanced heart failure (AHF) has become an American Board of Internal Medicine-certified subspecialty, new data are needed to benchmark and value levels of clinical effort performed by AHF specialists (AHFMDs). METHODS AND RESULTS:A 36-question survey was sent to 728 AHFMDs, member...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2015.08.340

    authors: Klein L,Greenberg BH,Konstam MA,Gregory D,Kociol RD,Johnson MR,de Marco T

    更新日期:2015-11-01 00:00:00

  • The impact of heart failure on the classification of COPD severity.

    abstract:BACKGROUND:Pulmonary restriction-a reduction of lung volumes-is common in heart failure (HF), rendering severity grading of chronic obstructive pulmonary disease (COPD) potentially problematic in subjects with both diseases. We compared pulmonary function in patients with either HF or COPD, or the combination to assess...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2012.05.008

    authors: Güder G,Rutten FH,Brenner S,Angermann CE,Berliner D,Ertl G,Jany B,Lammers JW,Hoes AW,Störk S

    更新日期:2012-08-01 00:00:00

  • Rationale and design of the enoximone clinical trials program.

    abstract:BACKGROUND:Chronic heart failure is a disease syndrome characterized in its advanced stages by a poor quality of life, frequent hospitalizations, and a high risk of mortality. In advanced and ultra-advanced chronic heart failure, many treatment options, such as cardiac transplantation and mechanical devices, are severe...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2005.10.013

    authors: Lowes BD,Shakar SF,Metra M,Feldman AM,Eichhorn E,Freytag JW,Gerber MJ,Liard JF,Hartman C,Gorczynski R,Evans G,Linseman JV,Stewart J,Robertson AD,Roecker EB,Demets DL,Bristow MR

    更新日期:2005-12-01 00:00:00

  • Outcomes of volume-overloaded cardiovascular patients treated with ultrafiltration.

    abstract:BACKGROUND:Ultrafiltration (UF) can rapidly and predictably remove extracellular and intravascular fluid volume. To date, assessment of UF in patients with cardiovascular disease has been confined to short- and medium-term studies in patients with a principal diagnosis of acute heart failure. METHODS:In-hospital and l...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2008.02.003

    authors: Jaski BE,Romeo A,Ortiz B,Hoagland PM,Stone M,Glaser D,Thomas L,Walsh C,Smith SC Jr

    更新日期:2008-08-01 00:00:00

  • Hemodynamic changes and neurohumoral regulation during development of congestive heart failure in a model of epinephrine-induced cardiomyopathy in conscious rabbits.

    abstract:BACKGROUND:The present study was designed to study the progression of heart failure in rabbits with catecholamine-induced cardiomyopathy. METHODS AND RESULTS:We investigated the effects of three repetitive applications (at 16-day intervals) of high-dose epinephrine (first infusion, 5 micrograms/kg/min for 60 minutes; ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/s1071-9164(99)90033-7

    authors: Muders F,Friedrich E,Luchner A,Pfeifer M,Ickenstein G,Hamelbeck B,Riegger GA,Elsner D

    更新日期:1999-06-01 00:00:00

  • Relevance of water gymnastics in rehabilitation programs in patients with chronic heart failure or coronary artery disease with normal left ventricular function.

    abstract:BACKGROUND:Exercise training is included in cardiac rehabilitation programs to enhance physical capacity and cardiovascular function. Among the existing rehabilitation programs, exercises in water are increasingly prescribed. However, it has been questioned whether exercises in water are safe and relevant in patients w...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.cardfail.2011.04.008

    authors: Teffaha D,Mourot L,Vernochet P,Ounissi F,Regnard J,Monpère C,Dugué B

    更新日期:2011-08-01 00:00:00

  • Prognostic impact of combined late gadolinium enhancement on cardiovascular magnetic resonance and peak oxygen consumption in ambulatory patients with nonischemic dilated cardiomyopathy.

    abstract:BACKGROUND:Peak oxygen consumption (peak VO₂) and late gadolinium enhancement (LGE) on cardiovascular magnetic resonance (CMR) are prognostic in heart failure. We investigated whether LGE-CMR and peak VO₂combined had additive value in risk stratifying patients with nonischemic dilated cardiomyopathy (DCM). METHODS AND...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2014.08.005

    authors: Yamada T,Hirashiki A,Okumura T,Adachi S,Shimazu S,Shimizu S,Morimoto R,Takeshita K,Naganawa S,Kondo T,Murohara T

    更新日期:2014-11-01 00:00:00

  • The role of right ventricular endomyocardial biopsy for idiopathic giant cell myocarditis.

    abstract:BACKGROUND:Idiopathic giant cell myocarditis (GCM) is an uncommon cause of cardiac failure distinguished clinically from lymphocytic myocarditis by rapidly progressive heart failure, arrhythmias, and heart block. Unlike fulminant lymphocytic myocarditis, patients with fulminant cardiac failure caused by GCM may respond...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1054/jcaf.2002.32196

    authors: Shields RC,Tazelaar HD,Berry GJ,Cooper LT Jr

    更新日期:2002-04-01 00:00:00

  • Improvement of serum NT-ProBNP predicts improvement in cardiac function and favorable prognosis after cardiac resynchronization therapy for heart failure.

    abstract:BACKGROUND:Cardiac resynchronization therapy (CRT) is now an established therapy for patients with advanced heart failure with electromechanical delay, although nonresponders have been observed. Because natriuretic peptides are relevant markers to reflect the severity of heart failure and filling pressure of cardiac ch...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2005.04.007

    authors: Yu CM,Fung JW,Zhang Q,Chan CK,Chan I,Chan YS,Kong SL,Sanderson JE,Lam CW

    更新日期:2005-06-01 00:00:00

  • Fibrosis and Fibrotic Gene Expression in Pediatric and Adult Patients With Idiopathic Dilated Cardiomyopathy.

    abstract:BACKGROUND:Although fibrosis seems to be prognostic for adverse outcomes in adults with idiopathic dilated cardiomyopathy (IDC), little is known about the prevalence and development of fibrosis in pediatric IDC hearts. We hypothesized that there is less activation of fibrosis at a molecular level in pediatric IDC heart...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2016.11.006

    authors: Woulfe KC,Siomos AK,Nguyen H,SooHoo M,Galambos C,Stauffer BL,Sucharov C,Miyamoto S

    更新日期:2017-04-01 00:00:00

  • Use of the aortoatrial continuity as means of providing left ventricular assist support without entering the ventricle: a feasibility study.

    abstract:BACKGROUND:Left ventricular assist devices (LVADs) are increasingly used to treat patients with refractory heart failure. Current-generation LVADs have major limitations, including the need for open chest surgery, limiting their widespread use. We hypothesized that the aortoatrial continuity could be used as a unique a...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2011.01.014

    authors: Friedman PA,Kushwaha SS,Bruce CJ,Park SJ,Ladewig DJ,Mikell SB,Johnson SB,Suddendorf SH,Danielsen AJ,Asirvatham SJ

    更新日期:2011-06-01 00:00:00

  • Right ventricular dysfunction and adverse outcome in patients with advanced heart failure.

    abstract:BACKGROUND:In patients with heart failure (HF) from left ventricular systolic dysfunction, the presence of coexistent right ventricular (RV) dysfunction is associated with poor exercise capacity and reduced survival. We sought to determine whether a simple measure of RV function, the RV myocardial performance index (RV...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2006.06.472

    authors: Field ME,Solomon SD,Lewis EF,Kramer DB,Baughman KL,Stevenson LW,Tedrow UB

    更新日期:2006-10-01 00:00:00

  • Cardiovascular magnetic resonance imaging detects cardiac involvement in Churg-Strauss syndrome.

    abstract:BACKGROUND:Cardiac involvement in Churg-Strauss vasculitis worsens the prognosis. Early detection is, therefore, warranted. Cardiac magnetic resonance (CMR) can visualize various forms of inflammatory changes in the myocardium. We tested whether CMR could elucidate cardiac damage in patients with biopsy-proven Churg-St...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2008.07.227

    authors: Wassmuth R,Göbel U,Natusch A,Schneider W,Kettritz R,Dietz R,Luft FC,Schulz-Menger J

    更新日期:2008-12-01 00:00:00

  • Assessing Barriers to Healthy Eating in Hospitalized Older Adults With Heart Failure: Psychometric Properties of Two Questionnaires.

    abstract:BACKGROUND:Dietary sodium excess and malnutrition have been associated with poor outcomes in heart failure (HF). Few previous studies have examined the barriers to following a low-sodium, nutritionally robust diet in hospitalized patients with HF. METHODS AND RESULTS:As part of a dietary intervention pilot study, 76 i...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章

    doi:10.1016/j.cardfail.2019.09.011

    authors: Marolt C,Miller A,Carlozzi NE,Karmally W,Helmke S,Teruya S,Wells J,Trumble E,Maurer MS,Hummel SL

    更新日期:2020-03-01 00:00:00

  • Prolonged electrical muscle stimulation exercise improves strength, peak VO2, and exercise capacity in patients with stable chronic heart failure.

    abstract:BACKGROUND:Exercise training can help patients with chronic heart failure but may be limited in its applicability due to age and other comorbidities. This investigation evaluated training responses to prolonged electrical muscle stimulation (EMS) in patients with stable chronic heart failure. METHODS AND RESULTS:In a ...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.cardfail.2008.11.005

    authors: Banerjee P,Caulfield B,Crowe L,Clark AL

    更新日期:2009-05-01 00:00:00

  • Muscle cell grafting for the treatment and prevention of heart failure.

    abstract:BACKGROUND:The review aims to highlight recent advances in cardiac and skeletal muscle cell grafting for myocardial infarct repair. RESULTS:Fetal and neonatal cardiomyocytes form new myocardium in normal or injured hearts, and this new myocardium differentiates toward an adult phenotype. Unfortunately, formation of ne...

    journal_title:Journal of cardiac failure

    pub_type: 杂志文章,评审

    doi:10.1054/jcaf.2002.129268

    authors: Murry CE,Whitney ML,Reinecke H

    更新日期:2002-12-01 00:00:00