Effectiveness of disinfection therapies and promotion of osteoblast growth on osseotite and nanotite implant surfaces.

Abstract:

OBJECTIVES:To evaluate the effectiveness of 4 procedures to disinfect implant surfaces intentionally inoculated with bacteria and afterward to evaluate osteoblast viability to the disinfected implant surfaces. MATERIALS AND METHODS:Eighty-eight commercially pure Osseotite and Nanotite titanium implant discs were inoculated with Porphyromonas gingivalis. The implant surfaces were disinfected with EDTA, tetracycline, citric acid, or neodymium-doped yttrium aluminum garnet (Nd:YAG) laser. The implant discs were then placed in cultures of osteoblast cells. RESULTS:Osseotite implant discs were easier to disinfect compared with the Nanotite implant discs. Citric acid and tetracycline were the most effective solutions for the disinfection of P. gingivalis from the Osseotite implant discs. CONCLUSION:The Nanotite implant discs were the most difficult to disinfect, likely because of their chemical and physical properties. Citric acid and tetracycline were most effective for disinfecting the Osseotite implant discs, and further clinical research is needed to verify these effects in vivo. The Nd:YAG laser was the weakest disinfection method, and it is not recommended for disinfecting implant surfaces until its effectiveness is improved.

journal_name

Implant Dent

journal_title

Implant dentistry

authors

Lubin J,Hernandez MA,Drukteinis SE,Parker WB,Murray PE

doi

10.1097/ID.0000000000000067

subject

Has Abstract

pub_date

2014-08-01 00:00:00

pages

426-33

issue

4

eissn

1056-6163

issn

1538-2982

journal_volume

23

pub_type

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