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The effect of saliva substitutes on enamel erosion in vitro.

Abstract：

OBJECTIVES:To investigate the effect of saliva substitutes on enamel erosion in vitro. METHODS:A total of 204 bovine enamel samples were embedded in acrylic resin and allocated to 17 groups (n=12). The specimens were eroded in an artificial mouth (3 days; 6×30 s/days, flow rate: 2 ml/min) using citric acid (pH: 2.5). Immediately after the erosive attacks, saliva substitutes (12 sprays, 3 gels) were applied. Between the erosive cycles the specimens were rinsed with artificial saliva (flowrate: 0.5 ml/min). A SnCl2/AmF/NaF-containing mouthrinse was used as positive control, water spray served as negative control. Enamel loss was measured profilometrically and the data were analyzed using one-way ANOVA followed by Scheffé's post hoc tests (p<0.05). RESULTS:Four saliva substitutes increased enamel erosion, probably due to the low pH or the content of citric acid. Several saliva substitutes were able to reduce enamel erosion significantly by 60-90% (in the range of the positive control). The protective potential of these products was in the range of the positive control (reduction of enamel loss to 30% of negative control). The erosion-protective potential of these high-viscous products is probably related to their film-forming properties, leading to a mechanical protection of the surface. CONCLUSION:Saliva substitutes containing a very low pH exhibit a distinct erosive potential, while most high-viscous products present an erosion-protective effect. It can be recommended that patients suffering from xerostomia and at high risk for dental erosion should use high-viscous saliva substitutes, but should avoid saliva substitutes with low pH or containing citric acid. CLINICAL SIGNIFICANCE:It can be recommended that patients suffering from xerostomia and at high risk for dental erosion should use high-viscous saliva substitutes, but should avoid saliva substitutes with low pH or containing citric acid.

journal_name

J Dent

journal_title

Journal of dentistry

authors

Aykut-Yetkiner A,Wiegand A,Attin T

doi

10.1016/j.jdent.2014.03.012

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

720-5

issue

eissn

0300-5712

issn

1879-176X

pii

S0300-5712(14)00093-1

journal_volume

pub_type

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The effect of saliva substitutes on enamel erosion in vitro.