Microarray-based ultra-high resolution discovery of genomic deletion mutations.

abstract：BACKGROUND:Leaf blight caused by Calonectria spp. is one of the most destructive diseases to affect Eucalyptus nurseries and plantations. These pathogens mainly attack Eucalyptus, a tree with a diversity of secondary metabolites employed as defense-related phytoalexins. To unravel the fungal adaptive mechanisms to vari...

journal_title：BMC genomics

authors： Ye X,Zhong Z,Liu H,Lin L,Guo M,Guo W,Wang Z,Zhang Q,Feng L,Lu G,Zhang F,Chen Q

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:To date several studies have sought to catalog the full suite of antibodies that humans naturally produce against single antigens or other specificities (repertoire). Here we analyze the properties of all sequenced repertoires in order to better understand the specificity of antibody responses. Specifically,...

journal_title：BMC genomics

authors： Arnaout RA

更新日期：2005-10-28 00:00:00

abstract：BACKGROUND:Increasing evidence suggests that overlapping genes are much more common in eukaryotic genomes than previously thought. In this study we identified and characterized the overlapping genes in a set of 13,484 pairs of human-mouse orthologous genes. RESULTS:About 10% of the genes under study are overlapping ge...

journal_title：BMC genomics

authors： Sanna CR,Li WH,Zhang L

更新日期：2008-04-14 00:00:00

abstract：BACKGROUND:Bread wheat has a large complex genome that makes whole genome resequencing costly. Therefore, genome complexity reduction techniques such as sequence capture make re-sequencing cost effective. With a high-quality draft wheat genome now available it is possible to design capture probe sets and to use them to...

journal_title：BMC genomics

authors： Olohan L,Gardiner LJ,Lucaci A,Steuernagel B,Wulff B,Kenny J,Hall N,Hall A

更新日期：2018-04-13 00:00:00

abstract：BACKGROUND:Adaptations to a new environment, such as a polluted one, often involve large modifications of the existing phenotypes. Changes in gene expression and regulation during critical developmental stages may explain these phenotypic changes. Embryos from a population of the teleost fish, Fundulus heteroclitus, in...

journal_title：BMC genomics

authors： Bozinovic G,Sit TL,Di Giulio R,Wills LF,Oleksiak MF

更新日期：2013-11-11 00:00:00

abstract：BACKGROUND:Adenosine to inosine (A-to-I) RNA-editing is an essential post-transcriptional mechanism that occurs in numerous sites in the human transcriptome, mainly within Alu repeats. It has been shown to have consistent levels of editing across individuals in a few targets in the human brain and altered in several hu...

journal_title：BMC genomics

authors： Greenberger S,Levanon EY,Paz-Yaacov N,Barzilai A,Safran M,Osenberg S,Amariglio N,Rechavi G,Eisenberg E

更新日期：2010-10-28 00:00:00

abstract：BACKGROUND:Soybean (Glycine max (L. Merr.)) resistance to any population of Heterodera glycines (I.), or Fusarium virguliforme (Akoi, O'Donnell, Homma & Lattanzi) required a functional allele at Rhg1/Rfs2. H. glycines, the soybean cyst nematode (SCN) was an ancient, endemic, pest of soybean whereas F. virguliforme caus...

journal_title：BMC genomics

authors： Srour A,Afzal AJ,Blahut-Beatty L,Hemmati N,Simmonds DH,Li W,Liu M,Town CD,Sharma H,Arelli P,Lightfoot DA

更新日期：2012-08-02 00:00:00

abstract：BACKGROUND:The insect order Neuroptera encompasses more than 5,700 described species. To date, only three neuropteran mitochondrial genomes have been fully and one partly sequenced. Current knowledge on neuropteran mitochondrial genomes is limited, and new data are strongly required. In the present work, the mitochondr...

journal_title：BMC genomics

authors： Negrisolo E,Babbucci M,Patarnello T

更新日期：2011-05-10 00:00:00

abstract：BACKGROUND:Progress in genetics and breeding in pea still suffers from the limited availability of molecular resources. SNP markers that can be identified through affordable sequencing processes, without the need for prior genome reduction or a reference genome to assemble sequencing data would allow the discovery and ...

journal_title：BMC genomics

authors： Boutet G,Alves Carvalho S,Falque M,Peterlongo P,Lhuillier E,Bouchez O,Lavaud C,Pilet-Nayel ML,Rivière N,Baranger A

更新日期：2016-02-18 00:00:00

abstract：BACKGROUND:While changes in chromosome number that result in aneuploidy are associated with phenotypic consequences such as Down syndrome and cancer, the molecular causes of specific phenotypes and genome-wide expression changes that occur in aneuploids are still being elucidated. RESULTS:We employed a segmental aneup...

journal_title：BMC genomics

authors： Makarevitch I,Phillips RL,Springer NM

更新日期：2008-01-10 00:00:00

abstract：BACKGROUND:Pectobacterium spp. are necrotrophic bacterial plant pathogens of the family Pectobacteriaceae, responsible for a wide spectrum of diseases of important crops and ornamental plants including soft rot, blackleg, and stem wilt. P. carotovorum is a genetically heterogeneous species consisting of three valid sub...

journal_title：BMC genomics

authors： Li X,Ma Y,Liang S,Tian Y,Yin S,Xie S,Xie H

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:Fungal plant pathogens belonging to the genus Venturia cause damaging scab diseases of members of the Rosaceae. In terms of economic impact, the most important of these are V. inaequalis, which infects apple, and V. pirina, which is a pathogen of European pear. Given that Venturia fungi colonise the sub-cuti...

journal_title：BMC genomics

authors： Deng CH,Plummer KM,Jones DAB,Mesarich CH,Shiller J,Taranto AP,Robinson AJ,Kastner P,Hall NE,Templeton MD,Bowen JK

更新日期：2017-05-02 00:00:00

abstract：BACKGROUND:Tomato plant growth is frequently hampered by a high susceptibility to pests and diseases. Traditional chemical control causes a serious impact on both the environment and human health. Therefore, seeking environment-friendly and cost-effective green methods in agricultural production becomes crucial nowaday...

journal_title：BMC genomics

authors： Zhou L,Song C,Li Z,Kuipers OP

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Atlantic salmon production in Tasmania (Southern Australia) occurs near the upper limits of the species thermal tolerance. Summer water temperatures can average over 19 °C over several weeks and have negative effects on performance and health. Liver tissue exerts important metabolic functions in thermal adap...

journal_title：BMC genomics

authors： Nuez-Ortín WG,Carter CG,Nichols PD,Cooke IR,Wilson R

更新日期：2018-02-12 00:00:00

abstract：BACKGROUND:Betula platyphylla is a common tree species in northern China that has high economic and medicinal value. Our laboratory has been devoted to genome research on B. platyphylla for approximately 10 years. As primary organelle genomes, the complete genome sequences of chloroplasts are important to study the div...

journal_title：BMC genomics

authors： Wang S,Yang C,Zhao X,Chen S,Qu GZ

更新日期：2018-12-20 00:00:00

abstract：BACKGROUND:In mammals, CEACAM1 and closely related members represent paired receptors with similar extracellular ligand-binding regions and cytoplasmic domains with opposing functions. Human CEACAM1 and CEACAM3 which have inhibitory ITIM/ITSM and activating ITAM-like motifs, respectively, in their cytoplasmic regions a...

journal_title：BMC genomics

authors： Zimmermann W,Kammerer R

更新日期：2016-11-16 00:00:00

abstract：BACKGROUND:Avian infectious bronchitis virus (IBV) is a gamma coronavirus that severely affects the poultry industry worldwide. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs with a length of more than 200 nucleotides, have been recently recognized as pivotal factors in the pathogenesis of viral infections...

journal_title：BMC genomics

authors： Li H,Cui P,Fu X,Zhang L,Yan W,Zhai Y,Lei C,Wang H,Yang X

更新日期：2021-01-20 00:00:00

abstract：BACKGROUND:Bacillus pumilus is a Gram-positive and endospore-forming bacterium broadly existing in a variety of environmental niches. Because it produces and secrets many industrially useful enzymes, a lot of studies have been done to understand the underlying mechanisms. Among them, scoC was originally identified as a...

journal_title：BMC genomics

authors： Han LL,Liu YC,Miao CC,Feng H

更新日期：2019-04-30 00:00:00

abstract：BACKGROUND:Compared to other ascomycetes, the barley powdery mildew pathogen Blumeria graminis f.sp. hordei (Bgh) has a large genome (ca. 120 Mbp) that harbors a relatively small number of protein-coding genes (ca. 6500). This genomic assemblage is thought to be the result of numerous gene losses, which likely represen...

journal_title：BMC genomics

authors： Kusch S,Ahmadinejad N,Panstruga R,Kuhn H

更新日期：2014-10-02 00:00:00

abstract：BACKGROUND:Large difference in cerebrum size exist between avian species and populations of the same species and is believed to reflect differences in processing power, i.e. in the speed and efficiency of processing information in this brain region. During domestication chickens developed a larger cerebrum compared to ...

journal_title：BMC genomics

authors： Höglund A,Strempfl K,Fogelholm J,Wright D,Henriksen R

更新日期：2020-07-29 00:00:00

abstract：BACKGROUND:Lower eggshell quality in the late laying period leads to economic loss. It is a major threat to the quality and safety of egg products. Age-related variations in ultrastructure were thought to induce this deterioration. Eggshell formation is a highly complex process under precise regulation of genes and bio...

journal_title：BMC genomics

authors： Feng J,Zhang HJ,Wu SG,Qi GH,Wang J

更新日期：2020-11-09 00:00:00

abstract：BACKGROUND:Previous studies show that galanin neurons in ventrolateral preoptic nucleus (VLPO-Gal) are essential for sleep regulation. Here, we explored the transcriptional regulation of the VLPO-Gal neurons in sleep by comparing their transcriptional responses between sleeping mice and those kept awake, sacrificed at ...

journal_title：BMC genomics

authors： Guo X,Gao X,Keenan BT,Zhu J,Sarantopoulou D,Lian J,Galante RJ,Grant GR,Pack AI

更新日期：2020-09-14 00:00:00

abstract：BACKGROUND:The sustainability of poultry farming relies on the development of more efficient and autonomous production systems in terms of feed supply. This implies a better integration of adaptive traits in breeding programs, including digestive efficiency, in order to favor the use of a wider variety of feedstuffs. T...

journal_title：BMC genomics

authors： Juanchich A,Hennequet-Antier C,Cabau C,Le Bihan-Duval E,Duclos MJ,Mignon-Grasteau S,Narcy A

更新日期：2018-12-13 00:00:00

abstract：BACKGROUND:Inadvertent sample swaps are a real threat to data quality in any medium to large scale omics studies. While matches between samples from the same individual can in principle be identified from a few well characterized single nucleotide polymorphisms (SNPs), omics data types often only provide low to moderat...

journal_title：BMC genomics

authors： Westphal M,Frankhouser D,Sonzone C,Shields PG,Yan P,Bundschuh R

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Despite substantial progress in mosquito genomic and genetic research, few cis-regulatory elements (CREs), DNA sequences that control gene expression, have been identified in mosquitoes or other non-model insects. Formaldehyde-assisted isolation of regulatory elements paired with DNA sequencing, FAIRE-seq, i...

journal_title：BMC genomics

authors： Behura SK,Sarro J,Li P,Mysore K,Severson DW,Emrich SJ,Duman-Scheel M

更新日期：2016-05-10 00:00:00

abstract：BACKGROUND:About 10% of cases of male infertility are due to the presence of microdeletions within the long arm of the Y chromosome (Yq). Despite the large literature covering this critical issue, very little is known about the pathogenic mechanism leading to spermatogenesis disruption in patients carrying these microd...

journal_title：BMC genomics

authors： Gatta V,Raicu F,Ferlin A,Antonucci I,Scioletti AP,Garolla A,Palka G,Foresta C,Stuppia L

更新日期：2010-06-24 00:00:00

abstract：BACKGROUND:Chemosensory receptors including olfactory receptors (ORs), gustatory receptors (GRs) and ionotropic receptors (IRs) play a central role in sensing chemical signals and guiding insect behaviours, and are potential target genes in insect pest control. The cotton bollworm Helicoverpa armigera is one of the mos...

journal_title：BMC genomics

authors： Liu NY,Xu W,Papanicolaou A,Dong SL,Anderson A

更新日期：2014-07-15 00:00:00

abstract：BACKGROUND:Alpha tubulin is a fundamental component of the cytoskeleton which is responsible for cell shape and is involved in cell division, ciliary and flagellar motility and intracellular transport. Alpha tubulin gene expression varies according to the morphological changes suffered by Leishmania in its life cycle. ...

journal_title：BMC genomics

authors： Ramírez CA,Requena JM,Puerta CJ

更新日期：2013-07-06 00:00:00

abstract：BACKGROUND:Transmembrane β-barrel proteins are a special class of transmembrane proteins which play several key roles in human body and diseases. Due to experimental difficulties, the number of transmembrane β-barrel proteins with known structures is very small. Over the years, a number of learning-based methods have b...

journal_title：BMC genomics

authors： Tran Vdu T,Chassignet P,Sheikh S,Steyaert JM

更新日期：2012-04-12 00:00:00

abstract：BACKGROUND:The development of second generation sequencing methods has enabled large scale DNA variation studies at moderate cost. For the high throughput discovery of single nucleotide polymorphisms (SNPs) in species lacking a sequenced reference genome, we set-up an analysis pipeline based on a short read de novo seq...

journal_title：BMC genomics

authors： Kerstens HH,Crooijmans RP,Veenendaal A,Dibbits BW,Chin-A-Woeng TF,den Dunnen JT,Groenen MA

更新日期：2009-10-16 00:00:00