Fruit flies learn to avoid odours associated with virulent infection.

Abstract:

:While learning to avoid toxic food is common in mammals and occurs in some insects, learning to avoid cues associated with infectious pathogens has received little attention. We demonstrate that Drosophila melanogaster show olfactory learning in response to infection with their virulent intestinal pathogen Pseudomonas entomophila. This pathogen was not aversive to taste when added to food. Nonetheless, flies exposed for 3 h to food laced with P. entomophila, and scented with an odorant, became subsequently less likely to choose this odorant than flies exposed to pathogen-laced food scented with another odorant. No such effect occurred after an otherwise identical treatment with an avirulent mutant of P. entomophila, indicating that the response is mediated by pathogen virulence. These results demonstrate that a virulent pathogen infection can act as an aversive unconditioned stimulus which flies can associate with food odours, and thus become less attracted to pathogen-contaminated food.

journal_name

Biol Lett

journal_title

Biology letters

authors

Babin A,Kolly S,Schneider F,Dolivo V,Zini M,Kawecki TJ

doi

10.1098/rsbl.2014.0048

subject

Has Abstract

pub_date

2014-03-05 00:00:00

pages

20140048

issue

3

eissn

1744-9561

issn

1744-957X

pii

rsbl.2014.0048

journal_volume

10

pub_type

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