Abstract:
:The neuropeptide galanin (GAL) was injected intrathecally (i.t.) in decerebrate, spinalized, unanesthetized rats and its effect on the nocifensive flexor reflex was examined. The reflex, which was evoked by intense mechanical or thermal stimulation of the foot, was recorded from the ipsilateral hamstring muscles. I.t. GAL increased reflex excitability significantly more to thermal than to mechanical stimuli. It is suggested that GAL, which is present in sensory fibers that innervate the skin, is released by the central terminals of cutaneous afferents that are much more sensitive to thermal than to mechanical stimuli.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Wiesenfeld-Hallin Z,Villar MJ,Hökfelt Tdoi
10.1007/BF00248760subject
Has Abstractpub_date
1988-01-01 00:00:00pages
663-6issue
3eissn
0014-4819issn
1432-1106journal_volume
71pub_type
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