A switch from constitutive chemical defence to inducible innate immune responses in the invasive ladybird Harmonia axyridis.

Abstract:

:The harlequin ladybird, Harmonia axyridis, has emerged as a model species for invasion biology, reflecting its remarkable capacity to outcompete native ladybird species when introduced into new habitats. This ability may be associated with its prominent resistance to pathogens and intraguild predation. We recently showed that the constitutive antibacterial activity present in the haemolymph of H. axyridis beetles can be attributed to the chemical defence compound harmonine. Here, we demonstrate that H. axyridis differs from other insects, including the native ladybird Coccinella septempunctata, by reducing rather than increasing the antimicrobial activity of its haemolymph following the injection of bacteria. However, both species produce new or more abundant proteins in the haemolymph, indicating that bacterial challenge induces innate immune responses associated with the synthesis of immunity-related proteins. Our results suggest that H. axyridis beetles can switch from constitutive chemical defence to inducible innate immune responses, supporting hypothesis that inducible antimicrobial peptides protect host beetles against pathogens that survive constitutive defences. These alternative antimicrobial defence mechanisms may reflect a trade-off resulting from fitness-related costs associated with the simultaneous synthesis of harmonine and antimicrobial peptides/proteins.

journal_name

Biol Lett

journal_title

Biology letters

authors

Schmidtberg H,Röhrich C,Vogel H,Vilcinskas A

doi

10.1098/rsbl.2013.0006

subject

Has Abstract

pub_date

2013-03-06 00:00:00

pages

20130006

issue

3

eissn

1744-9561

issn

1744-957X

pii

rsbl.2013.0006

journal_volume

9

pub_type

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