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The role of nutrition and diet in Alzheimer disease: a systematic review.

Abstract：

:The role of nutrition in modulating Alzheimer disease (AD) remains uncertain. Persons ingesting a Mediterranean-type diet appear to be less likely to develop AD. Epidemiologically, food combinations rich in antioxidant vitamins reduced the risk of AD. Combination formulas (eg, Souvenaid) appear to have small effects on cognition. B-vitamin supplements were mostly disappointing with inconsistent findings, except in countries where bread is not fortified with folate. They were generally negative, as were studies investigating omega-3 fatty acid supplementation. Based on this review, a Mediterranean diet and/or a combination supplement, such as Souvenaid, appear to be the most beneficial approaches with the least possible adverse effects to slowing the progression of AD.

journal_name

J Am Med Dir Assoc

journal_title

Journal of the American Medical Directors Association

authors

Shah R

doi

10.1016/j.jamda.2013.01.014

subject

Has Abstract

pub_date

2013-06-01 00:00:00

pages

398-402

issue

6

eissn

1525-8610

issn

1538-9375

pii

S1525-8610(13)00036-4

journal_volume

14

pub_type

杂志文章,评审

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