A randomized trial of aerobic versus resistance exercise in prostate cancer survivors.

Abstract:

:Androgen-deprivation therapy (ADT) for prostate cancer (PCa) has side effects that significantly impair health-related quality of life (HRQOL). Exercise ameliorates many side effects of ADT, but different modalities, particularly in the home-based setting, have not been well studied. In this study the authors randomly assigned 66 PCa survivors receiving ADT to 6 mo of home-based aerobic or resistance training. Psychosocial well-being and physical fitness were measured at baseline, 3 and 6 mo, and then 6 mo postintervention. Intention-to-treat analyses showed that fatigue and HRQOL were not significantly different between groups; however, in a per-protocol analysis the resistance-exercise training group demonstrated clinically significant improvements in HRQOL. Differential within-group effects on physical fitness were also observed at various time points. At all time points, the aerobic-training group engaged in significantly more physical activity than the resistance-training group, a finding that should be further examined given evidence-based guidelines for activity volume in cancer survivors.

journal_name

J Aging Phys Act

authors

Santa Mina D,Alibhai S MH,Matthew AG,Guglietti CL,Pirbaglou M,Trachtenberg J,Ritvo P

doi

10.1123/japa.21.4.455

subject

Has Abstract

pub_date

2013-10-01 00:00:00

pages

455-78

issue

4

eissn

1063-8652

issn

1543-267X

pii

2012-0187

journal_volume

21

pub_type

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