Changes in the synaptic region of auditory hair cells during noise-induced temporary threshold shift.

abstract：:The relation between hearing loss and loss of hair cells after prolonged exposure to a simulated industrial noise environment was determined in normotensive albino rats. Hearing loss was assessed behaviorally by a conditioned suppression technique and electrophysiologically by auditory brainstem response to pulses of ...

journal_title：Hearing research

authors： Borg E

更新日期：1987-01-01 00:00:00

abstract：:Animal model research has shown that the central features of tinnitus, the perception of sound without an acoustic correlate, include elevated spontaneous and stimulus-driven activity, enhanced burst-mode firing, decreased variance of inter-spike intervals, and distortion of tonotopic frequency representation. Less we...

journal_title：Hearing research

authors： Brozoski T,Brozoski D,Wisner K,Bauer C

更新日期：2017-07-01 00:00:00

abstract：:Gaumond et al. [(1982) J. Neurophysiol. 48, 856-873] showed in the cat that a multiplicative-intensity model can generally account quite well for reduction of the probability of an auditory-nerve spike by another spike preceding it by 4 to 25 ms, and that for smaller separations there is also an increased latency of t...

journal_title：Hearing research

authors： Ronken DA,Bosch WR,Molnar CE

更新日期：1993-09-01 00:00:00

abstract：:Long-term experience enhances neural representation of temporal attributes of pitch in the brainstem and auditory cortex in favorable listening conditions. Herein we examine whether cortical pitch mechanisms shaped by language experience are more resilient to degradation in background noise, and exhibit greater binaur...

journal_title：Hearing research

authors： Suresh CH,Krishnan A,Gandour JT

更新日期：2017-11-01 00:00:00

abstract：:Neural auditory thresholds in the guinea pig can be temporarily improved by up to 6 dB about 2 min after the cessation of an moderately intense low-frequency tone (Kirk and Patuzzi, 1997). We have measured changes in the f2-f1 distortion product otoacoustic emission (DPOAE) and low-frequency microphonic potential in s...

journal_title：Hearing research

authors： Kirk DL,Moleirinho A,Patuzzi RB

更新日期：1997-10-01 00:00:00

abstract：:The laminar distribution and reciprocity of commissural axon terminals and cells of origin in cat primary auditory cortex (AI) were studied after injections of tritiated proline combined with horseradish peroxidase in the middle ectosylvian gyrus. Terminal fields were found in every cortical layer in the contralateral...

journal_title：Hearing research

authors： Code RA,Winer JA

更新日期：1986-01-01 00:00:00

abstract：:The lipophilic dye, DiI, was placed into the macula lagena of paraformaldehyde-fixed embryonic chicks. Retrogradely labeled cells were found bilaterally in the pontine reticular formation (RF) between the dorsal facial nucleus and the abducens nerve root. This location is similar to that of the dorsomedial group of ef...

journal_title：Hearing research

authors： Code RA

更新日期：1995-01-01 00:00:00

abstract：:Alterations in the distribution and activity of Na,K-ATPase have been implicated in declining cell function with age. However, the location, size and anatomical complexity of the cochlea have limited study of this essential enzyme. Here we describe a micro-colorimetric assay which measures Na,K-ATPase activity in subr...

journal_title：Hearing research

authors： Gratton MA,Smyth BJ,Schulte BA,Vincent DA Jr

更新日期：1995-03-01 00:00:00

abstract：:Many natural sounds such as speech contain concurrent amplitude and frequency modulation (AM and FM), with the FM components often in the form of directional frequency sweeps or glides. Most studies of modulation coding, however, have employed one modulation type in stationary carriers, and in cases where mixed-modula...

journal_title：Hearing research

authors： Hsieh IH,Saberi K

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Noise-induced hearing loss (NIHL) is a multifactorial disease, and dysregulation of oxidative stress is universally acknowledged as one crucial pathogenic factor for this disease. Recently studies have found the LncRNA HOTAIR is involved in the alteration of oxidative stress level, cell proliferation, cell c...

journal_title：Hearing research

authors： Wang B,Ding E,Shen H,Wang J,Sun K,Chen S,Han L,Zhang H,Zhu B,Xu M

更新日期：2017-04-01 00:00:00

abstract：:Some important relationships between two auditory nonlinearities, unmasking and combination tone (CT) production, are described. An example of unmasking is provided by using a forward-masking paradigm where a baseline is first obtained by determining the threshold of a 2000 Hz signal preceded by a 2000 Hz masker. When...

journal_title：Hearing research

authors： Tyler RS

更新日期：1980-06-01 00:00:00

abstract：:We studied the 2IFC detectability of a 500 Hz tone masked by computer-generated maskers under the N0SII interaural condition, and under two masker conditions. In the first masker condition the maskers in the two intervals of a trial were independent of each other, and in the second masker condition the maskers were id...

journal_title：Hearing research

authors： Siegel RA,Colburn HS

更新日期：1983-08-01 00:00:00

abstract：:We performed transient evoked otoacoustic emission (TEOAE) measurements on 29 ears of myasthenia gravis (MG) patients. The purpose of the study was to support the role of acetylcholine (ACh) in the efferent innervation of cochlear outer hair cells (OHCs). Another aim was to establish additional diagnostic tools for th...

journal_title：Hearing research

authors： Tóth L,Rácz T,Diószeghy P,Répássy G,Lampé I

更新日期：1998-12-01 00:00:00

abstract：:The membrane glycoprotein CTL2/SLC44A2 is expressed by supporting cells in the inner ear and has been identified as a target of antibodies that may induce auto-immune hearing loss. To determine if CTL2/SLC44A2 also has roles in inner ear development and to distinguish between isoform-specific roles, we assessed age-re...

journal_title：Hearing research

authors： Beyer LA,Galano MM,Nair TS,Kommareddi PK,Sha SH,Raphael Y,Carey TE

更新日期：2011-12-01 00:00:00

abstract：:Behavioral studies on complex sound perception in goldfish were carried out in order to help determine what, if any, differences exist between the sense of hearing of fishes and other vertebrates. A stimulus generalization paradigm was used with classical conditioning in three experiments to determine: (1) the percept...

journal_title：Hearing research

authors： Fay RR

更新日期：1995-09-01 00:00:00

abstract：:Cisplatin-induced ototoxicity results in significant, permanent hearing loss in pediatric and adult cancer survivors. Elucidating the mechanisms underlying cisplatin-induced hearing loss as well as the development of therapies to reduce and/or reverse cisplatin ototoxicity have been impeded by suboptimal animal models...

journal_title：Hearing research

authors： Fernandez K,Wafa T,Fitzgerald TS,Cunningham LL

更新日期：2019-04-01 00:00:00

abstract：:Effects of stimulus level on discrimination of one stimulation site from another were examined in 15 human subjects with Nucleus-22 cochlear implant systems. Bipolar stimulation was used in all cases with electrodes in the bipolar pair separated by 1.5 mm (center to center). Subjects were first tested at a medium loud...

journal_title：Hearing research

authors： Pfingst BE,Holloway LA,Zwolan TA,Collins LM

更新日期：1999-08-01 00:00:00

abstract：:Binaural temporal resolution was measured using the discrimination of brief interaural time delays (ITDs). In experiment 1, three listeners performed a 2I-2AFC, ITD-discrimination procedure. ITD changes of 8 to 1024micros were applied to brief probe noises. These probes, with durations of 16 to 362ms, were placed symm...

journal_title：Hearing research

authors： Kolarik AJ,Culling JF

更新日期：2009-02-01 00:00:00

abstract：:Studies in several mammalian species have demonstrated that auditory cortical neurons respond strongly to single frequency-modulated (FM) sweeps, and that most responses are selective for sweep direction and/or rate. In the present study, we used extracellular recordings to examine how neurons in the auditory cortices...

journal_title：Hearing research

authors： Orduña I,Mercado E 3rd,Gluck MA,Merzenich MM

更新日期：2001-10-01 00:00:00

abstract：:This report concerns the morphological features of otoconia removed from the inner ear of four amphibian species. Results from scanning electron microscopic examination are compared based on the site of origin. These results show that utricular otoconia have a mineral structure that mimics calcite, rather than the wid...

journal_title：Hearing research

authors： Pote KG,Ross MD

更新日期：1993-05-01 00:00:00

abstract：:Thresholds to sinusoidal and biphasic pulsatile electrical stimuli were measured in two patients with electrodes positioned on the cochlear nucleus. The threshold functions differ from those observed in patients with scala tympani electrodes, primarily at low sinusoidal frequencies and long pulse widths. This differen...

journal_title：Hearing research

authors： Shannon RV

更新日期：1989-06-15 00:00:00

abstract：:Preservation of residual hearing after cochlear implantation is now considered an important goal of surgery. However, studies indicate an average post-operative hearing loss of around 20 dB at low frequencies. One factor which may contribute to post-operative hearing loss, but which has received little attention in th...

journal_title：Hearing research

authors： Elliott SJ,Ni G,Verschuur CA

更新日期：2016-11-01 00:00:00

abstract：:Previous investigations have shown that components of a tone burst-evoked otoacoustic emission (TBOAE) evoked by a 1 kHz tone burst (TB1) can be suppressed by the simultaneous presence of a 2 kHz tone burst (TB2) or a pair of tone bursts at 2 and 3 kHz (TB2 and TB3 respectively). No previous study has measured this "s...

journal_title：Hearing research

authors： Killan EC,Lutman ME,Thyer NJ

更新日期：2015-09-01 00:00:00

abstract：:Chronic tinnitus is often accompanied by a hearing impairment, but it is still unknown whether hearing loss can actually cause tinnitus. The association between the pitch of the tinnitus sensation and the audiogram edge in patients with high-frequency hearing loss suggests a functional relation, but a large fraction o...

journal_title：Hearing research

authors： König O,Schaette R,Kempter R,Gross M

更新日期：2006-11-01 00:00:00

abstract：:In natural environments, temporally complex signals often occur in a background of noise. The neural mechanisms underlying the preservation of temporal sensitivity in background noise are poorly understood. In the present study, we examined the ability of inferior colliculus (IC) units with primary-like and sustained ...

journal_title：Hearing research

authors： Barsz K,Wilson WW,Walton JP

更新日期：2000-12-01 00:00:00

abstract：:To create experimental lesions localized to the low frequency region of the organ of Corti, a cryoprobe was applied to the apical area of 37 cochleas from 26 adult chinchillas. Twenty cochleas were exposed to single applications of a cryoprobe for 2.5, 3.0 and 3.5 min; 17 cochleas were exposed to two applications of 1...

journal_title：Hearing research

authors： Brown JN,Nuttall AL

更新日期：1987-01-01 00:00:00

abstract：:Compound action potentials (AP) were recorded under various stimulus conditions in 31 guinea pigs. Stimulus attenuation, decrease of inter-stimulus interval, increase of the level of a continuous wide-band noise maker, and lowering the animal's temperature all resulted in a drop of the AP amplitude and an increase in ...

journal_title：Hearing research

authors： Prijs VF,Eggermont JJ

更新日期：1981-03-01 00:00:00

abstract：:Guinea pigs were exposed to pure tones of 10 kHz at intensities between 98 and 115 dB SPL for 5-30 min, to produce varying degrees of acoustic trauma. Changes in auditory thresholds were measured electrophysiologically, and the animals were immediately fixed for scanning electron microscopy. Correlation between morpho...

journal_title：Hearing research

authors： Clark JA,Pickles JO

更新日期：1996-09-15 00:00:00

abstract：:The primary goal of this study was to characterize the variability in auditory-nerve temporal response patterns obtained with the electrically evoked compound action potential (ECAP) within and across a relatively large group of cochlear-implant recipients. ECAPs were recorded in response to each of 21 pulses in a pul...

journal_title：Hearing research

authors： Hughes ML,Castioni EE,Goehring JL,Baudhuin JL

更新日期：2012-03-01 00:00:00

abstract：:Genetically manipulated mice have gained a prominent role in in vivo research on development and function of the auditory system. A prerequisite for the interpretation of normal and abnormal structural and functional features of the inner ear is the exact knowledge of the cochlear place-frequency map. Using a stereota...

journal_title：Hearing research

authors： Müller M,von Hünerbein K,Hoidis S,Smolders JW

更新日期：2005-04-01 00:00:00