Abstract:
:This study was undertaken to investigate the relative strengths of dural repair using standard suture techniques, suture supplemented with tissue adhesive, and tissue adhesive alone. Uniform 2 mm dural defects were created in adult beagles, repaired, and then subjected to pressurization testing. Defects repaired with suture alone initially leaked within the range of physiologic pressurization, while those supplemented with tissue adhesive or repaired with tissue adhesive alone failed at higher pressurization levels. Histologic sections obtained from the dura treated with fibrin adhesive sealant demonstrated minimal inflammatory response not significantly different than those sections examined at sites repaired by suture alone. A new substance, fibrin adhesive sealant, appears to be useful in effecting dural repair due to its ability to withstand pressures greater than those obtained with suture alone.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Cain JE Jr,Rosenthal HG,Broom MJ,Jauch EC,Borek DA,Jacobs RRdoi
10.1097/00007632-199009000-00024subject
Has Abstractpub_date
1990-09-01 00:00:00pages
969-70issue
9eissn
0362-2436issn
1528-1159journal_volume
15pub_type
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