Simplifying outcome measurement: evaluation of instruments for measuring outcome after fusion surgery for chronic low back pain.


STUDY DESIGN:A comparative evaluation of outcome instruments and global assessment was performed. OBJECTIVE:To test patient global assessment as a substitute for the use of more comprehensive outcome instruments in treatment trials of chronic low back pain. SUMMARY OF BACKGROUND DATA:Treatment outcome can be measured with pain scales and functional instruments. In the absence of a gold standard, the patient him- or herself is the basic reference for outcome, for which the instruments give a more or less exact measurement. Global assessment, which is a retrospective recording, may overestimate improvement as a result of recall or motivational bias. METHODS:In this study, 294 patients treated for chronic low back pain were evaluated with a visual analog scale for back pain, the Oswestry Disability Index, the Million Score and general function score for disease-specific disability, and the Zung Depression Scale for depressive symptoms. The correlation between the pretreatment and posttreatment scores for the outcome instruments (Delta scores) and the global assessment scores was calculated; effect sizes were compared; sensitivity and specificity with receiver operating characteristics (ROC) curves were estimated; and associations of global assessment with pretreatment and posttreatment scores were determined. RESULTS:All the Delta scores showed significant correlations with patient global assessment and with each other. The effect size of global assessment tended to be greater than that of the outcome instruments. The specificity and sensitivity of the disability instruments and pain scale were approximately 75%, whereas they were lower for depression. The associations between global assessment and outcome instrument scores did not produce evidence that global assessment was biased. CONCLUSION:Patient global assessment is a valid and responsive descriptor of overall effect in randomized controlled trials of treatment for chronic low back pain.


Spine (Phila Pa 1976)




Hägg O,Fritzell P,Odén A,Nordwall A,Swedish Lumbar Spine Study Group.





Has Abstract


2002-06-01 00:00:00














  • Are There 3D Changes in Spine and Rod Shape in the 2 Years After Adolescent Idiopathic Scoliosis Instrumentation?

    abstract:STUDY DESIGN:Retrospective analysis of spine and rods 3D shape in the 2 years after adolescent idiopathic scoliosis (AIS) posterior surgical instrumentation. OBJECTIVE:To evaluate spine and rod shape 3D changes in the 2 years after AIS instrumentation with different rod materials. SUMMARY OF BACKGROUND DATA:Postopera...


    pub_type: 杂志文章


    authors: Le Navéaux F,Labelle H,Parent S,Newton PO,Aubin CE

    更新日期:2017-08-01 00:00:00

  • Absence of biglycan accelerates the degenerative process in mouse intervertebral disc.

    abstract:STUDY DESIGN:A study of the histologic changes of the intervertebral discs (IVDs) in biglycan (Bgn)-deficient mice. OBJECTIVE:In this study, we investigate whether the absence of Bgn accelerates the degenerative process in mouse intervertebral disc (IVD). SUMMARY OF BACKGROUND DATA:Proteoglycans and collagen fibrils ...


    pub_type: 杂志文章


    authors: Furukawa T,Ito K,Nuka S,Hashimoto J,Takei H,Takahara M,Ogino T,Young MF,Shinomura T

    更新日期:2009-12-01 00:00:00

  • Operative treatment of spinal fractures with the AO internal fixator.

    abstract::A multicentered prospective trial to investigate the usefulness of the AO spinal internal fixator for the treatment of thoracolumbar fractures and fracture-dislocations was undertaken. This pedicle screw-rod system was effective in stabilizing a variety of unstable fracture patterns. It was effective in decompressing ...


    pub_type: 杂志文章


    authors: Esses SI,Botsford DJ,Wright T,Bednar D,Bailey S

    更新日期:1991-03-01 00:00:00

  • The applied anatomy of the thoracolumbar fascia.

    abstract::The thoracolumbar fascia was studied by dissection in ten adult human cadavers. The posterior layer of this fascia was found to consist of two laminae. The superficial lamina is formed by the aponeurosis of latissimus dorsi. The deep lamina consists of bands of fibers passing caudolaterally from the midline. Both lami...


    pub_type: 杂志文章


    authors: Bogduk N,Macintosh JE

    更新日期:1984-03-01 00:00:00

  • Validation of the simplified Chinese version of the functional rating index for patients with nonspecific neck pain in mainland China.

    abstract:STUDY DESIGN:Validation of a self-report questionnaire, Functional Rating Index (FRI). OBJECTIVE:To evaluate the psychometric properties of the simplified Chinese (SC) version of FRI in patients with nonspecific neck pain (NP). SUMMARY OF BACKGROUND DATA:FRI has been cross-culturally validated in few languages with e...


    pub_type: 杂志文章


    authors: Wei X,Xu X,Zhao Y,Chen K,Wang F,Fan J,Yang C,Chen Z,Bai Y,Zhu X,Li M

    更新日期:2015-05-01 00:00:00

  • Interaction of 5-hydroxytryptamine and tumor necrosis factor-α to pain-related behavior by nucleus pulposus applied on the nerve root in rats.

    abstract:STUDY DESIGN:The effects of exogenous 5-hydroxytryptamine (5-HT), tumor necrosis factor(TNF)-α, 5-HT + TNF in combination, and autologous nucleus pulposus (NP) at dorsal root ganglion (DRG) were examined using rat models. OBJECTIVE:To examine the interaction of 5-HT with TNF for pain-related behavior in a rat lumbar d...


    pub_type: 杂志文章


    authors: Kobayashi H,Kikuchi S,Konno S,Kato K,Sekiguchi M

    更新日期:2011-02-01 00:00:00

  • Can Elective Spine Surgery Be Performed Safely Among Nonagenarians?: Analysis of a National Inpatient Database in Japan.

    abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:To compare morbidity and mortality between nonagenarians and other older adult patients who underwent elective spine surgery. SUMMARY OF BACKGROUND DATA:There is a lack of information of the perioperative risks of nonagenarians undergoing spine surgery. METHODS:Data...


    pub_type: 杂志文章


    authors: Oichi T,Oshima Y,Matsui H,Fushimi K,Tanaka S,Yasunaga H

    更新日期:2019-03-01 00:00:00

  • Outcomes of workers' compensation claimants with low back pain undergoing intradiscal electrothermal therapy.

    abstract:STUDY DESIGN:Case series. OBJECTIVE:To describe the outcomes of workers' compensation (WC) claimants who have had a lumbar intradiscal electrothermal therapy (IDET) procedure. SUMMARY OF BACKGROUND DATA:IDET was developed as a less invasive treatment alternative to fusion after failure of conservative treatment for d...


    pub_type: 杂志文章


    authors: Webster BS,Verma S,Pransky GS

    更新日期:2004-02-15 00:00:00

  • Multifidus Muscle Changes After Back Injury Are Characterized by Structural Remodeling of Muscle, Adipose and Connective Tissue, but Not Muscle Atrophy: Molecular and Morphological Evidence.

    abstract:STUDY DESIGN:Longitudinal case-controlled animal study. OBJECTIVE:To investigate putative cellular mechanisms to explain structural changes in muscle and adipose and connective tissues of the back muscles after intervertebral disc (IVD) injury. SUMMARY OF BACKGROUND DATA:Structural back muscle changes are ubiquitous ...


    pub_type: 杂志文章


    authors: Hodges PW,James G,Blomster L,Hall L,Schmid A,Shu C,Little C,Melrose J

    更新日期:2015-07-15 00:00:00

  • Association Between Surgeon Experience and Complication Rates in Adult Scoliosis Surgery: A Review of 5117 Cases From the Scoliosis Research Society Database 2004-2007.

    abstract:STUDY DESIGN:Retrospective review of a multicenter database. OBJECTIVE:To evaluate whether surgeon experience is associated with complication rates in adult spinal deformity (ASD) surgery. SUMMARY OF BACKGROUND DATA:Multiple patient- and surgery-related factors have been shown to increase the risk of complications in...


    pub_type: 杂志文章


    authors: Skovrlj B,Cho SK,Caridi JM,Bridwell KH,Lenke LG,Kim YJ

    更新日期:2015-08-01 00:00:00

  • Sensory innervation of the sacroiliac joint in rats.

    abstract:STUDY DESIGN:The segmental levels of dorsal root ganglions innervating the sacroiliac joint in rats were investigated using the retrograde transport method. The pathways and functions of the nerve fibers supplying the sacroiliac joint were determined by immunohistochemical detection of transported tracer. OBJECTIVES:T...


    pub_type: 杂志文章


    authors: Murata Y,Takahashi K,Yamagata M,Takahashi Y,Shimada Y,Moriya H

    更新日期:2000-08-15 00:00:00

  • A prospective study of centralization of lumbar and referred pain. A predictor of symptomatic discs and anular competence.

    abstract:STUDY DESIGN:The presence or absence of rapidly centralizing, peripheralizing, or abolishing low back and radiating pain, as identified during a McKenzie mechanical lumbar assessment of patients with chronic lumbar pain, was compared prospectively with discographic pain provocation and anular competency. OBJECTIVES:To...


    pub_type: 杂志文章


    authors: Donelson R,Aprill C,Medcalf R,Grant W

    更新日期:1997-05-15 00:00:00

  • A Study on the Anatomical Relationship of the Lumbar Extrapedicular Puncture Approach with the Spinal Nerve and its Branches.

    abstract:STUDY DESIGN:An anatomical study in fifteen cadavers. OBJECTIVE:To observe the anatomical relationship of the extrapedicular puncture approach with the spinal nerve and its branches, evaluate the risk of injury to these nerves and recommend a safe puncture path for lumbar extrapedicular percutaneous vertebroplasty (PV...


    pub_type: 杂志文章


    authors: Zhong Y,Luo L,Zhao C,Li P,Dong B,Wang Z,Jiang D,Zhou Q,Liu L

    更新日期:2021-01-08 00:00:00

  • Discrimination validity of the scoliosis research society-22 patient questionnaire: relationship to idiopathic scoliosis curve pattern and curve size.

    abstract:STUDY DESIGN:Prospective observational study. OBJECTIVE:To determine the discriminant validity of the Scoliosis Research Society-22 (SRS-22) health-related quality-of-life (HRQL) questionnaire for idiopathic scoliosis patients based on curve pattern and curve size. SUMMARY OF BACKGROUND DATA:An important psychometric...


    pub_type: 杂志文章


    authors: Asher M,Min Lai S,Burton D,Manna B

    更新日期:2003-01-01 00:00:00

  • Spatial relations between the vertebral body and the thoracic aorta in adolescent idiopathic scoliosis.

    abstract:STUDY DESIGN:An analysis of computed tomography images of patients with adolescent idiopathic scoliosis. OBJECTIVES:To evaluate the spatial relations between the vertebral body and the thoracic aorta and to verify the safety of anterior instrumentation surgery. SUMMARY OF BACKGROUND DATA:Recent studies have suggested...


    pub_type: 杂志文章


    authors: Maruyama T,Takeshita K,Nakamura K,Kitagawa T

    更新日期:2004-09-15 00:00:00

  • The Relationship Between Lumbar Lateral Listhesis and Radiculopathy in Adult Scoliosis.

    abstract:STUDY DESIGN:Retrospective review and prospective validation study. OBJECTIVE:To develop a classification system of lumbar lateral listhesis that suggests different likelihoods of having radiculopathy in adult scoliosis. SUMMARY OF BACKGROUND DATA:The association of lumbar lateral listhesis with radiculopathy remains...


    pub_type: 杂志文章


    authors: Kleimeyer JP,Liu N,Hu SS,Cheng I,Alamin T,Grottkau BE,Kukreja S,Wood KB

    更新日期:2019-07-15 00:00:00

  • How does free rod-sliding affect the posterior instrumentation for a dynamic stabilization using a bovine calf model?

    abstract:STUDY DESIGN:A biomechanical cadaveric study in lumbar calf spine. OBJECTIVE:Evaluation of the effects of selected degrees of freedom (df) on the dynamic stabilization of the spine in terms of segmental range of motion (RoM), center of rotation (CoR), and implant loadings. SUMMARY OF BACKGROUND DATA:For dorsal stabil...


    pub_type: 杂志文章


    authors: Schulze M,Hartensuer R,Gehweiler D,Vordemvenne T,Raschke MJ,Trautwein F,Heuer F

    更新日期:2015-02-01 00:00:00

  • Surgical mystery: where is the missing pituitary rongeur tip?

    abstract:STUDY DESIGN:Case report. OBJECTIVE:We report the unusual case of a patient who was referred to our institution after she sustained an intraoperative injury to the common iliac vein during posterior lumbar discectomy at L5-S1 with a pituitary rongeur. There was only minimal bleeding with spontaneous hemostasis and no ...


    pub_type: 杂志文章


    authors: Bydon A,Xu R,Conte JV,Gokaslan ZL,Brinker JA,Witham TF,Yassari R

    更新日期:2010-08-01 00:00:00

  • Microscopic lysis of lumbar adhesive arachnoiditis.

    abstract::The results of a long-term study of 28 patients operated on for adhesive lumbar arachnoiditis are presented. The technique involved was microscopic lysis of adhesions. The first case of surgery was performed in 1966 and the last, in 1970, with followup through 1976. Numerous observations are made regarding the clinica...


    pub_type: 杂志文章


    authors: Johnston JD,Matheny JB

    更新日期:1978-03-01 00:00:00

  • Discography and magnetic resonance imaging in the diagnosis of lumbar disc disruption.

    abstract::Four cases of patients with normal magnetic resonance (MR) studies of the lumbar spine and abnormal discography are presented to illustrate that normal lumbar disc signal intensity does not necessarily rule out disc degeneration. ...


    pub_type: 杂志文章


    authors: Kornberg M

    更新日期:1989-12-01 00:00:00

  • Measuring physical and psychosocial function in patients with low-back pain.

    abstract::Techniques for assessing daily function in Patients with back pain are generally crude and limited in scope. We therefore examined a "health status" questionnaire, the Sickness Impact Profile (SIP) to assess its measurement characteristics in such patients. Eighty patients with mechanical low-back pain completed the S...


    pub_type: 杂志文章


    authors: Deyo RA,Diehl AK

    更新日期:1983-09-01 00:00:00

  • Who should have surgery for an intervertebral disc herniation? Comparative effectiveness evidence from the spine patient outcomes research trial.

    abstract:STUDY DESIGN:Combined prospective randomized controlled trial and observational cohort study of intervertebral disc herniation (IDH), an as-treated analysis. OBJECTIVE:To determine modifiers of the treatment effect (TE) of surgery (the difference between surgical and nonoperative outcomes) for intervertebral disc hern...


    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Pearson A,Lurie J,Tosteson T,Zhao W,Abdu W,Mirza S,Weinstein J

    更新日期:2012-01-15 00:00:00

  • Three-dimensional movements of the whole lumbar spine and lumbosacral joint.

    abstract::Knowledge of the normal movements of whole lumbar spine and lumbosacral joint is important for evaluating clinical pathologic conditions that may potentially produce unstable situations in these regions. At present there are few studies that report systemic three-dimensional movement analysis of these regions. The pur...


    pub_type: 杂志文章


    authors: Yamamoto I,Panjabi MM,Crisco T,Oxland T

    更新日期:1989-11-01 00:00:00

  • High graft resorption rates with dense cancellous allograft in anterior cervical discectomy and fusion.

    abstract:STUDY DESIGN:Radiographic review. OBJECTIVE:To determine whether dense cancellous allografts (DCAs) are associated with graft resorption when used in anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA:The ideal graft material for ACDF remains to be identified. Purported advantages of DCA inclu...


    pub_type: 杂志文章


    authors: Rhee JM,Patel N,Yoon ST,Franklin B

    更新日期:2007-12-15 00:00:00

  • Dual Time-Point 18F-FDG PET/CT in Spinal Sarcoidosis: A Single Institution Case Series.

    abstract:STUDY DESIGN:A case series of dual time-point F-fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography (F-FDG PET/CT) for the diagnosis of spinal cord sarcoidosis. OBJECTIVE:The aim of this study was to illustrate three cases of spinal sarcoidosis with occult presentation and subsequent identificati...


    pub_type: 杂志文章


    authors: Ordóñez-Rubiano EG,Solano-Noguera DF,Row W,Weinberg J,Tatsui CE,Johnson JM,Gule-Monroe MK

    更新日期:2019-11-01 00:00:00

  • Does an Annular Puncture Influence the Herniation Path?: An In Vitro Mechanical and Structural Investigation.

    abstract:STUDY DESIGN:A study of mechanically induced herniation in punctured ovine discs followed by structural analysis. OBJECTIVE:To investigate whether an annular puncture influences the path that herniation takes by providing direct passage for nucleus through the annulus and therefore whether it increases the risk of acu...


    pub_type: 杂志文章


    authors: van Heeswijk VM,Thambyah A,Robertson PA,Broom ND

    更新日期:2018-04-01 00:00:00

  • Using tissue expanders in spinal surgery for deficient soft tissue or postirradiation cases.

    abstract::Prior irradiation and scarring can complicate wound closure following spinal surgery. Implanted tissue expanders were used six times in four patients to aid skin closure. Three patients had prior irradiation for cancer, and one had myelomeningocele. The average interval between placement and removal of the expanders w...


    pub_type: 杂志文章


    authors: Paonessa KJ,Zide B,Errico T,Engler GL

    更新日期:1991-08-01 00:00:00

  • Development of a New Zealand white rabbit model of spinal pseudarthrosis repair and evaluation of the potential role of OP-1 to overcome pseudarthrosis.

    abstract:STUDY DESIGN:Posterolateral lumbar fusions were performed in nicotine-exposed, New Zealand white rabbits. Animals that developed a pseudarthrosis were then regrafted with no graft, autograft, or osteogenic protein-1 (OP-1). OBJECTIVES:To establish a model of pseudarthrosis repair and to evaluate the ability of OP-1 to...


    pub_type: 杂志文章


    authors: Grauer JN,Vaccaro AR,Kato M,Kwon BK,Beiner JM,Patel TC,Hilibrand AS,Chiba K,Albert TJ

    更新日期:2004-07-01 00:00:00

  • Left thoracic scoliosis configurations. Why so different?

    abstract:STUDY DESIGN:Patients in the scoliosis screening database were analyzed with respect to curve convexity, severity, and outcome, using standard statistical methods. OBJECTIVES:This study assessed whether left thoracic scoliosis is always pathologic and inquired why this is the case. SUMMARY OF BACKGROUND DATA:Left tho...


    pub_type: 杂志文章


    authors: Goldberg CJ,Dowling FE,Fogarty EE

    更新日期:1994-06-15 00:00:00

  • The functional rating index: reliability and validity of the Persian language version in patients with neck pain.

    abstract:STUDY DESIGN:Psychometric testing of the Persian Functional Rating Index (PFRI). OBJECTIVE:To determine the reliability and validity of the PFRI in Persian-speaking subjects with neck pain (NP). SUMMARY OF BACKGROUND DATA:The Functional Rating Index is a self-report questionnaire that can be used for patients with ba...


    pub_type: 杂志文章


    authors: Ansari NN,Feise RJ,Naghdi S,Mohseni A,Rezazadeh M

    更新日期:2012-06-15 00:00:00