Defining reference values of trace elements in the tear film: diagnostic methods and possible applications.

Abstract:

:The study has been performed on tears of apparently healthy subjects who live and work in urban and rural areas, respectively. After the collection the following elements were investigated: chromium (Cr); arsenic (As); copper (Cu); zinc (Zn); selenium (Se); rubidium (Rb); barium (Ba); lead (Pb) and cobalt (Co). Significantly higher values of As were found in subjects living and working in rural areas as compared to those found in urban area residents (0.290 vs. 0.025; p<0.001). Conversely, Ba and Pb were significantly lower in rural area residents (1.10 vs. 2.50, p=0.027 and 1.70 vs. 1.10, p=0.057, respectively). Our data show that trace elements analysis in tears is possible; further studies could define if it could be a reliable biomarker in persons exposed to high concentration of trace elements due to working or environmental reasons.

journal_name

Ecotoxicol Environ Saf

authors

Semeraro F,Costagliola C,Cancarini A,Gilberti E,Tosco E,Apostoli P

doi

10.1016/j.ecoenv.2012.02.021

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

190-4

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(12)00061-9

journal_volume

80

pub_type

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