当前位置： SCI文献检索 > ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY期刊下所有文献 > Experimental exposure of blue mussels (Mytilus galloprovincialis) to high levels of benzo[a]pyrene and possible implications for human health.

Experimental exposure of blue mussels (Mytilus galloprovincialis) to high levels of benzo[a]pyrene and possible implications for human health.

Abstract：

:Polycyclic aromatic hydrocarbons (PAHs) are lipophilic compounds able to accumulate in the food chain. Mussels showed to bioaccumulate contaminants, such as PAHs, so that recurrent consumption of such contaminated food represents a risk for human health. This study was aimed to elucidate if acute exposure of Mediterranean blue mussel (Mytilus galloprovincialis), a bivalve of great economic importance in several countries, to a PAH, benzo[a]pyrene (B[a]P), at doses able to induce cytochrome P450 1A (CYP1A) and pathological changes in mussel gills, can produce accumulation in soft tissue. We explored the cytotoxic effects (cell viability, DNA laddering, and glutathione levels) of in vitro exposure of human peripheral blood mononuclear cells (PBMCs) to organic extracts obtained from blue mussels previously exposed for 12 and 72h via water to B[a]P (0.5-1mg/L). In our experimental conditions, B[a]P induced CYP1A induction and morphological changes in mussel gills and a significant B[a]P accumulation in soft tissue. Conversely, exposing PBMCs to organic extracts obtained from contaminated mussels, resulted in a significant reduction of cell viability and cell glutathione content, and in an increase in DNA laddering. This confirms that consumption of mussels from B[a]P polluted waters might affect human health. Our data lead us to suggest that CYP1A activity in mussel gills may be useful (more than the amount of detected PAHs in the mussel edible tissue) as a marker in assessment of risk for health of consumers exposed to PAHs through ingestion of shellfish.

journal_name

Ecotoxicol Environ Saf

journal_title

Ecotoxicology and environmental safety

authors

Speciale A,Zena R,Calabrò C,Bertuccio C,Aragona M,Saija A,Trombetta D,Cimino F,Lo Cascio P

doi

10.1016/j.ecoenv.2017.12.038

subject

Has Abstract

pub_date

2018-04-15 00:00:00

pages

96-103

eissn

0147-6513

issn

1090-2414

pii

S0147-6513(17)30873-4

journal_volume

150

pub_type

杂志文章

相关文献

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY文献大全
  • Kinetics of the uptake of 14C-labeled chlorinated benzenes from soil by plants.

    abstract：:[14C]Benzene, [14C]1,2,4-trichlorobenzene, [14C]pentachlorobenzene, and [14C]hexachlorobenzene were applied to soils in outdoor lysimeters to a 10-cm depth (2 mg/kg dry soil); barley and cress plants were grown for one vegetation period and analyzed after varying time intervals. The bioaccumulation factors (concentrat...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/0147-6513(89)90034-1

    authors： Topp E,Scheunert I,Korte F

    更新日期：1989-04-01 00:00:00

  • Bioaccumulation of mercury in various fish species from Orlík and Kamýk water reservoirs in the Czech Republic.

    abstract：:The study evaluated contamination of fish by mercury in two important Czech water reservoirs, Orlík and Kamýk, which receive water from the whole watershed of Otava and Vltava rivers. Contamination of these reservoirs reflects the situation in southern and western Bohemia. Six environmentally representative sites were...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1999.1783

    authors： Svobodová Z,Dusek L,Hejtmánek M,Vykusová B,Smíd R

    更新日期：1999-07-01 00:00:00

  • Influence of EDTA and chemical species on arsenic accumulation in Spirodela polyrhiza L. (duckweed).

    abstract：:The influence of ethylenediaminetetraacetic acid (EDTA) and chemical species on arsenic accumulation in aquatic floating macrophyte Spirodela polyrhiza L. (duckweed) was investigated. The uptake of inorganic arsenic species (arsenate; As(V) and arsenite; As(III)) into the plant tissue and their adsorption on iron plaq...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2007.07.009

    authors： Rahman MA,Hasegawa H,Ueda K,Maki T,Rahman MM

    更新日期：2008-06-01 00:00:00

  • Asparagus densiflorus in a vertical subsurface flow phytoreactor for treatment of real textile effluent: A lab to land approach for in situ soil remediation.

    abstract：:This study explores the potential of Asparagus densiflorus to treat disperse Rubin GFL (RGFL) dye and a real textile effluent in constructed vertical subsurface flow (VSbF) phytoreactor; its field cultivation for soil remediation offers a real green and economic way of environmental management. A. densiflorus decolori...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.05.078

    authors： Watharkar AD,Kadam SK,Khandare RV,Kolekar PD,Jeon BH,Jadhav JP,Govindwar SP

    更新日期：2018-10-01 00:00:00

  • Mixture toxicity assessment of a biocidal product based on reproduction and avoidance behaviour of the collembolan Folsomia candida.

    abstract：:Biocidal products represent mixtures that might be released into the environment at application and continuously during service life. Concentration addition (CA) has been proposed as default model to calculate theoretical mixture toxicity. However, the suitability of CA for chronic toxicity towards soil organisms has ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.08.094

    authors： Guimarães B,Bandow C,Amorim MJB,Kehrer A,Coors A

    更新日期：2018-12-15 00:00:00

  • Phytotoxic mechanisms of bur cucumber seed extracts on lettuce with special reference to analysis of chloroplast proteins, phytohormones, and nutritional elements.

    abstract：:Bioherbicides from plant extracts are an effective and environmentally friendly method to prevent weed growth. The present investigation was aimed at determining the inhibitory effect of bur cucumber seed extracts (BSE) on lettuce plant growth. Bur cucumber seeds were ground with water, and two different concentration...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2015.07.015

    authors： Lee SM,Radhakrishnan R,Kang SM,Kim JH,Lee IY,Moon BK,Yoon BW,Lee IJ

    更新日期：2015-12-01 00:00:00

  • Remediation of lead polluted soil by active silicate material prepared from coal fly ash.

    abstract：:To improve the effect of coal fly ash on the remediation of heavy metal polluted soils, the active silicate material (ASM) was prepared by coal fly ash and the remediation of lead polluted soils by ASM was investigated in this study. To study the reaction mechanism between ASM and Pb(II) in soil, the Pb(II) adsorption...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.111409

    authors： Lei C,Chen T,Zhang QY,Long LS,Chen Z,Fu ZP

    更新日期：2020-12-15 00:00:00

  • Di(2-ethylhexyl) adipate plasticizer triggers hepatic, brain, and cardiac injury in rats: Mitigating effect of Peganum harmala oil.

    abstract：:Di(2-ethylhexyl) adipate (DEHA) is a widely used plasticizer and prevalent environmental contaminant. In this study, DEHA concentrations in the milk, cheese, and butter samples wrapped with food-grade commercial polyethylene films and stored at 4 °C for 30 days were detected using gas chromatographic analysis. Also, t...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2020.111620

    authors： Behairy A,Abd El-Rahman GI,Aly SSH,Fahmy EM,Abd-Elhakim YM

    更新日期：2021-01-15 00:00:00

  • Maleic acid assisted improvement of metal chelation and antioxidant metabolism confers chromium tolerance in Brassica juncea L.

    abstract：:Chromium (Cr) is a highly toxic environmental pollutant that negatively affects plant growth and development. Thus, remediating Cr from soil or increasing plant tolerance against Cr stress is urgent. Organic acids are recognized as agents of phytoremediation and as exogenous protectants, but using maleic acid (MA) to ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.06.010

    authors： Mahmud JA,Hasanuzzaman M,Nahar K,Rahman A,Hossain MS,Fujita M

    更新日期：2017-10-01 00:00:00

  • Evidence of metabolic microevolution of the limpet Nacella concinna to naturally high heavy metal levels in Antarctica.

    abstract：:The gastropod Nacella concinna is the most conspicuous macroinvertebrate of the intertidal zone of the Antarctic Peninsula and adjacent islands. Naturally high levels of copper and cadmium in coastal marine ecosystems are accumulated in N. concinna tissues. We aimed to study the effects of metal cations on N. concinna...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.09.007

    authors： de Oliveira MF,Rodrigues Júnior E,Suda CNK,Vani GS,Donatti L,Rodrigues E,Lavrado HP

    更新日期：2017-01-01 00:00:00

  • Photosynthesis inhibition by phenylureas: a QSAR approach.

    abstract：:A series of 21 N'-phenyl-N,N-disubstituted ureas was studied for its effects on thylakoidal electron transfer, photophosphorylation, and photosynthetic O2 evolution in class A chloroplasts and leaf fragments. The concentrations of test compounds that produced 50% inhibition of PS II electron transfer and of photosynth...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1994.1040

    authors： Arnaud L,Taillandier G,Kaouadji M,Ravanel P,Tissut M

    更新日期：1994-07-01 00:00:00

  • Wetland macrophyte community response to and recovery from direct application of glyphosate-based herbicides.

    abstract：:Community-scale impacts of glyphosate-based herbicides on wetland plant communities and the magnitude of those impacts that should be considered biologically relevant are poorly understood. We contrast three different thresholds for setting biologically meaningful critical effect sizes for complex ANOVA study designs....

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.109475

    authors： Mudge JF,Houlahan JE

    更新日期：2019-11-15 00:00:00

  • Bioaccumulation, sublethal toxicity, and biotransformation of sediment-associated pentachlorophenol in Lumbriculus variegatus (Oligochaeta).

    abstract：:The xenobiotics accumulated in sediments represent a hazard to organisms. In order to study the toxic effects of xenobiotics in organisms, body residue has been proposed as a more relevant dose-metric than the environmental concentration of the chemical. In this study, the benthic oligochaetes Lumbriculus variegatus w...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2006.12.019

    authors： Mäenpää K,Sorsa K,Lyytikäinen M,Leppänen MT,Kukkonen JV

    更新日期：2008-01-01 00:00:00

  • Cadmium retention and distribution in contaminated soil: effects and interactions of soil properties, contamination level, aging time and in situ immobilization agents.

    abstract：:As soil cadmium (Cd) contamination becomes a serious concern and one of the significant environmental pollution issues all over the world, knowledge of the basic chemistry, origin, inputs, sources, quantity, chemical forms, reactions, as well as the fate and transport of Cd in different types of soil is crucial for be...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.03.001

    authors： Marković J,Jović M,Smičiklas I,Šljivić-Ivanović M,Onjia A,Trivunac K,Popović A

    更新日期：2019-06-15 00:00:00

  • Rapid toxicity prediction of organic chemicals to Chlorella vulgaris using quantitative structure-activity relationships methods.

    abstract：:This paper presents the results of an optimization study on the toxicity of 91 aliphatic and aromatic compounds as well as a small subset of pesticides to algae Chlorella vulgaris, which was accomplished by using quantitative structure-activity relationships (QSAR). The linear (HM) and the nonlinear method radial basi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2008.09.002

    authors： Xia B,Liu K,Gong Z,Zheng B,Zhang X,Fan B

    更新日期：2009-03-01 00:00:00

  • The toxicity of zinc to terrestrial isopods in a "standard" laboratory test.

    abstract：:A method is described for assessing the effects of metals on the food consumption rate of isopods from measurements of fecal production. The effects of zinc in the diets of two isopod species, Porcellio scaber and Oniscus asellus, were tested. The metal was fed to the isopods on leaves of field maple (Acer campestre) ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1995.1037

    authors： Drobne D,Hopkin SP

    更新日期：1995-06-01 00:00:00

  • Bioaccumulation, oxidative stress and genotoxicity in fish (Channa punctatus) exposed to a thermal power plant effluent.

    abstract：:Metal bioaccumulation and induction of biomarkers such as lipid peroxidation (LPO), superoxide dismutase (SOD), catalase (CAT), glutathione S transferase (GST), reduced glutathione (GSH) and DNA damage are potential indicators of stress in Channa punctatus exposed to effluents. In canal water, receiving thermal power ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.01.007

    authors： Javed M,Ahmad I,Usmani N,Ahmad M

    更新日期：2016-05-01 00:00:00

  • Cadmium-induced stress response of Phanerochaete chrysosporium during the biodegradation of 2,2',4,4'-tetrabromodiphenyl ether (BDE-47).

    abstract：:Cd-induced stress response of Phanerochaete chrysosporium during the biodegradation of BDE-47 was investigated in this study, with the goal of elucidating the tolerance behavior and the detoxification mechanisms of P. chrysosporium to resist the Cd stress in the course of BDE-47 biodegradation, which has implications ...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.02.018

    authors： Feng M,Yin H,Cao Y,Peng H,Lu G,Liu Z,Dang Z

    更新日期：2018-06-15 00:00:00

  • Risk assessment of three fluoroquinolone antibiotics in the groundwater recharge system.

    abstract：:Three fluoroquinolone antibiotics agents (FQs) in groundwater and reclaimed water have been investigated in Changzhou and Beijing, China. The occurrence of ofloxacin (OFL), enrofloxacin (ENR) and norfloxacin (NOR) is in nanograms per liter and has 100% frequency. The concentration order of FQs in reclaimed water is NO...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2016.05.030

    authors： Chen G,Liu X,Tartakevosky D,Li M

    更新日期：2016-11-01 00:00:00

  • Development of broad spectrum antibodies to heat shock protein 70s as biomarkers for detection of multiple stress by pollutants and environmental factors.

    abstract：:To test the hypothesis that broad spectrum antibodies may be developed as biomarkers useful in detecting the consequence of combined environmental stresses in a wide variety of tissues and organisms, a stretch of 16 amino acids, TVPAYFNDSQRQATKDA, a well-conserved portion of heat shock 70 proteins, was identified, aga...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1006/eesa.1997.1544

    authors： Dunlap DY,Matsumura F

    更新日期：1997-08-01 00:00:00

  • Toxicodynamics of subacute co-exposure to groundwater contaminant arsenic and analgesic-antipyretic drug acetaminophen in rats.

    abstract：:Arsenic is an environmental contaminant, while acetaminophen is an extensively used nonsteroidal analgesic-antipyretic drug. We evaluated whether subacute co-exposure to arsenic and acetaminophen would produce more toxicity than that caused by exposure to either of the xenobiotics in rats. Toxicity was evaluated throu...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2009.09.005

    authors： Manimaran A,Sarkar SN,Sankar P

    更新日期：2010-01-01 00:00:00

  • Expression and functional analysis of cytochrome P450 genes in the wolf spider Pardosa pseudoannulata under cadmium stress.

    abstract：:Cytochrome P450 enzymes (CYPs), encoded by Halloween genes, mediate the biosynthesis of molting hormone, ecdysteroids, in arthropods. In this report, the effect of heavy metal cadmium (Cd) stress on the expression of cytochrome P450 genes in the wolf spider Pardosa pseudoannulata was analyzed. The results showed the e...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.01.034

    authors： Wang J,Lv Z,Lei Z,Chen Z,Lv B,Yang H,Wang Z,Song Q

    更新日期：2019-05-15 00:00:00

  • Effects of graphene oxide on cadmium uptake and photosynthesis performance in wheat seedlings.

    abstract：:Graphene oxide (GO) is extensively used in various fields because of its versatility. The presence of GO in the environment enhances the toxicity of toxicants or pollutants. Cadmium (Cd) and GO pollution is a problem in aquatic environment, which should be solved. We investigated the toxic effects of Cd on photosynthe...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.01.093

    authors： Gao M,Yang Y,Song Z

    更新日期：2019-05-30 00:00:00

  • Effect of cadmium on the ovarian development in the freshwater prawn Macrobrachium rosenbergii (De Man).

    abstract：:In this investigation, effect of cadmium chloride (25 μg/l) on oogenesis of freshwater prawn, Macrobrachium rosenbergii was studied. In vivo experiments were performed with both intact and eyestalk ablated prawns. The intact, cadmium-exposed prawns exhibited decrease in Gonado Somatic Index (GSI) and ovarian developme...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2010.08.027

    authors： Revathi P,Vasanthi LA,Munuswamy N

    更新日期：2011-05-01 00:00:00

  • Biotransformation of tetrabromobisphenol A (TBBPA) in anaerobic digester sludge, soils, and freshwater sediments.

    abstract：:The biotransformation of tetrabromobisphenol A (TBBPA) was evaluated in anaerobic digester sludge, soils, and freshwater sediments. In anaerobic digester sludge, TBBPA biotransformed rapidly with a 50% disappearance time (DT50) of 19 days, though little mineralization (1.1%) was observed. In aerobic soils, mineralizat...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2015.07.009

    authors： McAvoy DC,Pittinger CA,Willis AM

    更新日期：2016-09-01 00:00:00

  • Heavy metals in human urine, foods and drinking water from an e-waste dismantling area: Identification of exposure sources and metal-induced health risk.

    abstract：:Electronic waste or e-waste dismantling activities are known to release metals. However, the human exposure pathways of metals, and their association with oxidative stress in e-waste dismantling areas (EDAs) remain unclear. In this study, our results revealed elevated geometric mean concentrations in vegetables (Cd 0....

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2018.10.039

    authors： Zhang T,Ruan J,Zhang B,Lu S,Gao C,Huang L,Bai X,Xie L,Gui M,Qiu RL

    更新日期：2019-03-01 00:00:00

  • Using 2003-2014 U.S. NHANES data to determine the associations between per- and polyfluoroalkyl substances and cholesterol: Trend and implications.

    abstract：:Exposure to per- and polyfluoroalkyl substances (PFASs) is a major concern due to their widespread occurrence and adverse health outcomes. The possible binding of PFASs to peroxisome proliferator-activated receptors (PPARs) and nuclear receptors raises concerns that PFASs may impact cholesterol levels in human. In thi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2019.02.061

    authors： Dong Z,Wang H,Yu YY,Li YB,Naidu R,Liu Y

    更新日期：2019-05-30 00:00:00

  • Assisted phytoremediation of heavy metal contaminated soil from a mined site with Typha latifolia and Chrysopogon zizanioides.

    abstract：:Chemically assisted phytoremediation is fast gaining attention as a biotechnology to accelerate heavy metal removal from contaminated substrates, but how different chemical amendments affect the process remains an important research question. Here, bioaccumulation factor (BAF), translocation factor (TF), removal effic...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2017.10.014

    authors： Anning AK,Akoto R

    更新日期：2018-02-01 00:00:00

  • Historical residues of organochlorine pesticides (OCPs) and polycyclic aromatic hydrocarbons (PAHs) in a flood sediment profile from the Longwang Cave in Yichang, China.

    abstract：:Historical residual of persistent organic pollutants (POPs) in flood sediment from a karst cave were investigated. Fifteen vertical sediment samples were collected from a 6 m-deep flood sediment profile in the Longwang Cave, and the concentrations of organochlorine pesticides (OCPs), polycyclic aromatic hydrocarbons (...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 历史文章,杂志文章

    doi：10.1016/j.ecoenv.2020.110542

    authors： Qian Z,Mao Y,Xiong S,Peng B,Liu W,Liu H,Zhang Y,Chen W,Zhou H,Qi S

    更新日期：2020-06-15 00:00:00

  • Goldmining and mercury contamination of the piscivorous fish Hoplias aimara in French Guiana (Amazon basin).

    abstract：:Mercury contamination of 35 freshwater fish species collected from the upper part of the Petit-Saut hydroelectric reservoir (French Guiana) was analyzed in relation to their food regimes. Results showed marked biomagnification: the ratio between extreme Hg concentrations in the muscle from piscivorous species (14.3 mi...

    journal_title：Ecotoxicology and environmental safety

    pub_type： 杂志文章

    doi：10.1016/j.ecoenv.2004.05.004

    authors： Durrieu G,Maury-Brachet R,Boudou A

    更新日期：2005-03-01 00:00:00