Prediction of eye color from genetic data using Bayesian approach.

Abstract:

:Prediction of visible traits from genetic data in certain forensic cases may provide important information that can speed up the process of investigation. Research that has been conducted on the genetics of pigmentation has revealed polymorphisms that explain a significant proportion of the variation observed in human iris color. Here, on the basis of genetic data for the six most relevant eye color predictors, two alternative Bayesian network model variants were developed and evaluated for their accuracy in prediction of eye color. The first model assumed eye color to be categorized into blue, brown, green, and hazel, while the second variant assumed a simplified classification with two states: light and dark. It was found that particularly high accuracy was obtained for the second model, and this proved that reliable differentiation between light and dark irises is possible based on analysis of six single nucleotide polymorphisms and a Bayesian procedure of evidence interpretation.

journal_name

J Forensic Sci

authors

Pośpiech E,Draus-Barini J,Kupiec T,Wojas-Pelc A,Branicki W

doi

10.1111/j.1556-4029.2012.02077.x

subject

Has Abstract

pub_date

2012-07-01 00:00:00

pages

880-6

issue

4

eissn

0022-1198

issn

1556-4029

journal_volume

57

pub_type

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