Abstract:
OBJECTIVES:The Clot Lysis Evaluating Accelerated Resolution of Intraventricular Hemorrhage Trial phase III is a multicenter, randomized clinical trial in the management and treatment of subjects with small intracerebral hemorrhage and large intraventricular hemorrhage. Accurate localization, segmentation, and quantification of hemorrhage are necessary for decision making and treatment. Our studies are aimed at developing algorithms for accurate and automatic hemorrhage segmentation for this trial. METHODS:Two hundred one computed tomography scans of 41 patients with 2.5- to 10-mm slice thickness from 10 hospitals were used. Techniques based on thresholding, clustering, and graph theory modified using textural energy-based normalization were used along with preprocessing (filtering, skull stripping) and postprocessing (artifact removal). The segmented results of each method are compared with the ground truths. RESULTS:The median sensitivity, specificity, and dice statistical index (DSI) are 86.19%, 99.94%, and 0.8655 for modified thresholding; 83.23%, 99.93%, and 0.8410 for modified fuzzy C-means; and 87.28%, 99.81%, and 0.7917 for modified normalized cut method, respectively. The preprocessing and postprocessing enhanced the DSI by 10% and 3%, respectively. Usage of textural energy along with the Hounsfield value in the modified methods increased the DSI by about 8% to 10%. The methods reduced the time needed for processing from 20 to 30 minutes to 2 to 3 minutes per case. CONCLUSIONS:The modified thresholding provided the highest accuracy, least computation time, and implementation complexity compared with other 2 methods. The method reduces the time to localize and segment the hemorrhagic regions and also provides quantitative information that is critical to precise therapeutic decision making.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
KN BP,Hu J,Morgan TC,Hanley D,Nowinski WLdoi
10.1097/RCT.0b013e318245c1fasubject
Has Abstractpub_date
2012-01-01 00:00:00pages
109-20issue
1eissn
0363-8715issn
1532-3145pii
00004728-201201000-00018journal_volume
36pub_type
杂志文章,多中心研究,随机对照试验abstract:OBJECTIVE:Prior work has described the relationship between pulmonary vascular pruning on computed tomography (CT) scans and metrics of right-sided heart dysfunction in smokers. In this analysis, we sought to look at pruning on a lobar level, as well as examine the effect of the arterial and venous circulation on this ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000465
更新日期:2016-11-01 00:00:00
abstract:PURPOSE:Our goal was to determine the number of malignancies detected by thoracic CT in patients with head and neck squamous cell carcinoma (SCCA) in three clinical settings. METHOD:We retrospectively examined 168 thorax CT scans in 93 patients with head and neck SCCA and determined the number of malignancies (second ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199705000-00014
更新日期:1997-05-01 00:00:00
abstract::We describe a case with a focally spared area in fatty liver caused by arterioportal shunt. Furthermore, we discuss the cause of the focally spared area related to a localized dilution or reduction in portal blood flow. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199605000-00005
更新日期:1996-05-01 00:00:00
abstract::A case of a recurrent submandibular pleomorphic adenoma with metastasis in which both the primary tumor and metastasis were histologically benign is reported and the literature reviewed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-198711000-00043
更新日期:1987-11-01 00:00:00
abstract:OBJECTIVE:This study aimed to determine optimal strength of sinogram-affirmed iterative reconstruction (SAFIRE) and to evaluate image quality (IQ) of low-dose chest computed tomography (LDCT) using SAFIRE compared with iterative reconstruction in image space (IRIS) and filtered back projection (FBP). METHODS:Thirty pa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31828f4dae
更新日期:2013-07-01 00:00:00
abstract:OBJECTIVE:To retrospectively compare delayed enhanced computed tomography (CT) and 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET)/CT (PET/CT) evaluating adrenal masses in oncology patients undergoing both examinations. METHODS:Twenty adrenal masses in 14 patients were retrospectively included. For d...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/rct.0b013e31802fa8e1
更新日期:2007-07-01 00:00:00
abstract::Hepatocellular carcinoma and cholangiocarcinoma are the most common primary liver malignancies in adults (comprising >85%); however, liver is also host to some unusual primary malignant tumors. Some of these tumors show distinct demographic, clinicopathologic, and imaging features. Imaging features of these uncommon p...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000382
更新日期:2016-05-01 00:00:00
abstract:PURPOSE:Acinar cell carcinoma (ACC) is a subtype of pancreatic neoplasm sufficiently rare that its imaging has not been fully analyzed. The purpose of this article is to present the computed tomography (CT) appearance of ACC of the pancreas. METHODS:Clinical data and CT studies of 10 patients (7 male and 3 female) wit...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200403000-00005
更新日期:2004-03-01 00:00:00
abstract::The typical CT findings of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) are a hypodense nonenhancing unilateral posterior fossa mass, with or without adjacent occipital thinning, hydrocephalus, and calcification. Magnetic resonance (MR) has been found to be very helpful, and superior to CT, in...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199011000-00022
更新日期:1990-11-01 00:00:00
abstract::Several inconstant skull base foramina can be observed on multi-detector-row computed tomographic studies. These include the meningo-orbital foramen, foramen of Vesalius, canaliculus innominatus, palatovaginal canal, persistent craniopharyngeal canal, transsphenoidal canal, canalis basilaris medianus, and fossa navicu...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318289b370
更新日期:2013-07-01 00:00:00
abstract::Protocols for two- and three-dimensional phase contrast magnetic resonance angiography of the major vessels in the abdomen were developed and demonstrated in healthy volunteers. Phase contrast imaging provides excellent suppression of stationary tissue signal and can be used to quantify the speed and direction of flow...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199009000-00020
更新日期:1990-09-01 00:00:00
abstract::Although computed tomography (CT) delineation of normal white matter of the cerebral hemispheres has been well documented, there has been no description of white matter within the cerebellum. Through the use of phantom studies, CT number correlations between cerebellum and cerebral hemispheres, and anatomic correlatio...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197804000-00005
更新日期:1978-04-01 00:00:00
abstract::We report an unusual case of diffuse infiltration of the mesentery by amyloidosis. The CT, sonographic, and operative findings mimicked abdominal carcinomatosis. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Sixty-one CT scans in 20 patients who had undergone head and neck reconstructive surgery using a pectoralis major myocutaneous (PM-MC) flap were retrospectively evaluated to assess the usefulness of Ct in the follow-up of these patients. The normal CT findings in patients with PM-MC flaps are described. Of 13 cases wi...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199003000-00024
更新日期:1990-03-01 00:00:00
abstract::Congenital hyperinsulinism can be divided into diffuse or focal form. The treatment and outcome depend on distinguishing between the 2 forms. Pancreatic venous sampling was the only method available to localize the insulin secretion. [F]Fluoro-levodopa, 3,4-dihydroxy-L-phenylalanine positron emission tomography/comput...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318031f55c
更新日期:2007-09-01 00:00:00
abstract::The CT findings in hepatic involvement by Echinococcus granulosus are described. Pathognomonic signs of the hydatid nature of a cystic lesion are visualization of the cystic wall on plain CT, calcification of the cyst wall, daughter cysts, and membrane detachment. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198410000-00005
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to investigate the early manifestation of hypervascular hepatocellular carcinomas by means of evaluating the "nodule-in-nodule" hepatic lesions depicted on dynamic computed tomography. METHODS:For 26 lesions with hypervascular foci in nonhypervascular nodules in 23 patients with...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181670fa3
更新日期:2009-01-01 00:00:00
abstract::Computed tomography (CT) has enabled noninvasive evaluation of coronary bypass graft patency. Thirty-three patients operated on with 75 venous coronary bypass grafts were studied in the early postoperative period. Scans were taken with geometric magnification with a field of view of 16 or 24 cm, which gave a high spat...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198112000-00006
更新日期:1981-12-01 00:00:00
abstract::Thirty patients with suspected or known chronic aortic dissection were imaged with magnetic resonance (MR), CT, and angiography. Five of these patients had previously undergone surgical repair of the ascending aorta for a type A dissection. Magnetic resonance demonstrated an intimal flap and a double lumen in 25 cases...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198711000-00009
更新日期:1987-11-01 00:00:00
abstract::Our retrospective study of 230 computed tomographic (CT) studies of hepatic masses yielded 28 cases (12.2%) which contained calcification. Calcific deposits were noted in 9 of 59 patients (15.3%) with hepatocellular carcinoma (HCC), 15 of 82 patients (18.3%) with liver metastases from colorectal carcinoma (MCRC), 2 of...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198302000-00015
更新日期:1983-02-01 00:00:00
abstract::Two cases of necrotizing herpes simplex encephalitis (HSE) were investigated with 99mTc-hexamethylpropyleneamineoxime (HMPAO) SPECT and MR. The clinical course was compared with the neuroimaging results. In the acute stage, the increased HMPAO uptake matched the MR hyperintense signal in the limbic temporal lobe and i...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199109000-00016
更新日期:1991-09-01 00:00:00
abstract::This article reviews the computed tomography imaging features of a variety of gastric tumors containing fatty tissue. Lipoma, angiolipoma, liposarcoma, and teratoma are described. Differential diagnosis includes primary and reactive lipomatosis, carcinoma engulfing the perivisceral fat thus mimicking differentiated li...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/00004728-200011000-00006
更新日期:2000-11-01 00:00:00
abstract::Pneumatosis cystoides coli (PCC) is an uncommon condition in which multiple gas-filled cysts in the walls of the colon. Patients with PCC initially complain of various symptoms including abdominal discomfort, constipation, diarrhea, hematochezia, vomiting, and fever. We recently diagnosed PCC by computed tomography (C...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/rct.0b013e31805d08ca
更新日期:2008-01-01 00:00:00
abstract::We present two cases demonstrating, on CT examination, heavily calcified mass lesions associated with malignant pleural mesothelioma in workers occupationally exposed to asbestos. These masses proved to be osteogenic sarcomatous degeneration within mesotheliomas. The observation of dense calcification within a pleural...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199601000-00009
更新日期:1996-01-01 00:00:00
abstract::A 72-year-old woman with previously symptomatic internal carotid artery occlusion subsequently presented with an acute hemispheric deficit. The patient was initially diagnosed as having an ischemic infarction but eventually was shown to have a subacute subdural hematoma with delay in surgical evacuation and a major pe...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198909000-00029
更新日期:1989-09-01 00:00:00
abstract::The use of CT in the documentation of ancient Egyptian mummified human remains has previously been described in this and other journals. We recently applied this technique to a collection of ancient Egyptian mummified fauna and sarcophagi. We selected an example to illustrate that CT is also uniquely suitable for the ...
journal_title:Journal of computer assisted tomography
pub_type: 历史文章,杂志文章
doi:10.1097/00004728-198707000-00044
更新日期:1987-07-01 00:00:00
abstract::A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198412000-00015
更新日期:1984-12-01 00:00:00
abstract::Three cases of normal soft tissue collections of the right hilum which could be confused with thrombus of the right pulmonary artery or adenopathy are demonstrated. These abnormalities are due to normal accumulations of hilar fat and lymph nodes. Their typical appearance allows easy recognition. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198701000-00011
更新日期:1987-01-01 00:00:00
abstract:PURPOSE:First-pass perfusion magnetic resonance imaging (MRI) is a promising technique for detecting ischemic heart disease. However, the diagnostic value of the method is limited by the low spatial coverage, resolution, signal-to-noise ratio (SNR), and cardiac motion-related image artifacts. A combination of sliding w...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3181e9e9dd
更新日期:2010-09-01 00:00:00
abstract::Cooperative patients can often keep still during a long examination of the brain provided that they are given cues about their position in space. In a U-shaped head support, the only movements likely are rotation in the sagittal or transverse planes. These can be detected by a nasal orientation device (NOD), simply a ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199001000-00038
更新日期:1990-01-01 00:00:00