Family environment is associated with HPA-axis activity in adolescents. The TRAILS study.

Abstract:

:The purpose of the present study was to investigate the developmental programming part of the theory of biological sensitivity to context using family environmental factors and hypothalamus-pituitary-adrenal (HPA) axis functioning. Specifically, we investigated whether perceived parenting (Rejection and Emotional Warmth) and socio-economic status (SES) predicted basal cortisol levels and the cortisol awakening response (CAR). In a population-based cohort of 1594 adolescents (mean age=11.08, SD=0.54) we assessed salivary cortisol, SES and perceived parenting. Perceived parental Emotional Warmth showed an inverse, linear association with basal cortisol levels. In addition, there was a curvilinear relationship between SES and both basal cortisol levels and the CAR. Our findings with regard to basal cortisol levels confirmed our hypothesis: lower basal HPA-axis activity in both high and low SES families compared to intermediate SES families.

journal_name

Biol Psychol

journal_title

Biological psychology

authors

Marsman R,Nederhof E,Rosmalen JG,Oldehinkel AJ,Ormel J,Buitelaar JK

doi

10.1016/j.biopsycho.2011.12.013

subject

Has Abstract

pub_date

2012-02-01 00:00:00

pages

460-6

issue

2

eissn

0301-0511

issn

1873-6246

pii

S0301-0511(11)00314-0

journal_volume

89

pub_type

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