Patient characteristics associated with end-of-life decision making in critically ill surgical patients.

Abstract:

BACKGROUND:Palliative care is an important and necessary humanistic facet of ICU care. Wide variations exist in selection and implementation of palliative care decisions. Understanding patient factors associated with these decisions is crucial. STUDY DESIGN:Consecutive deaths (n = 151 patients) in a tertiary care surgical ICU during a 2-year period were reviewed. All data had been entered into the APACHE IV database. Patients were divided into groups: Withhold (WH), which included patients who had potentially lifesaving therapies withheld or withdrawn, and Full Care (FC), which included patients who had full resuscitative efforts before death. Patient factors including demographics, severity of illness, admission source, and history were compared between groups. RESULTS:Of 151 patients, 111 (74%) had potentially lifesaving therapy withheld or withdrawn (WH group). Forty patients (26%) had full treatment, including CPR, until time of death (FC group). Compared with WH, FC patients had a higher degree of illness at ICU admission (APACHE IV score 103.4 ± 36.6 vs 90.6 ± 29.3; p < 0.02) and were less likely to be male (35% vs 62%; p < 0.005). There were no differences between groups with regard to age, requirement for intubation on admission, medical history, admission source (emergency room vs operating room vs recovery room) or the number of patients admitted status post emergent vs elective surgery or admitted for nonsurgical diagnoses. In a multivariable regression model, male sex (odds ratio = 3.22; 95% CI, 1.45-7.19) and severity of illness (odds ratio = 0.98; 95% CI, 0.97-0.99) retained independent associations with decisions to limit care. CONCLUSIONS:Higher severity of illness and history play no role in the decision to limit care. Sex plays a strong and independent role. Factors influencing end-of-life care require additional study.

journal_name

J Am Coll Surg

authors

Lissauer ME,Naranjo LS,Kirchoffner J,Scalea TM,Johnson SB

doi

10.1016/j.jamcollsurg.2011.09.003

subject

Has Abstract

pub_date

2011-12-01 00:00:00

pages

766-70

issue

6

eissn

1072-7515

issn

1879-1190

pii

S1072-7515(11)01054-4

journal_volume

213

pub_type

杂志文章
  • Nationwide Outcomes Measurement in Colorectal Cancer Surgery: Improving Quality and Reducing Costs.

    abstract:BACKGROUND:Recent literature suggests that focus in health care should shift from reducing costs to improving quality; where quality of health care improves, cost reduction will follow. Our primary aim was to investigate whether improving the quality of surgical colorectal cancer care, by using a national quality impro...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.09.020

    authors: Govaert JA,van Dijk WA,Fiocco M,Scheffer AC,Gietelink L,Wouters MW,Tollenaar RA

    更新日期:2016-01-01 00:00:00

  • Cecectomy for complicated appendicitis.

    abstract:BACKGROUND:Cecal leak or disruption after appendectomy for complicated appendicitis is a consequence of severity of disease and is related to residual abscess cavity, inflammation, phlegmon, and nonviable intestine. In an attempt to improve results, we have begun to resect the cecum and other localized infected tissue ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Thompson JE Jr,Bennion RS,Schmit PJ,Hiyama DT

    更新日期:1994-08-01 00:00:00

  • Sex-Based Differences in Ten-Year Nationwide Outcomes of Carotid Revascularization.

    abstract:BACKGROUND:We compared the rates of stroke, death, and/or MI between men and women, stratified by symptomatic status and procedure type (carotid endarterectomy [CEA] or carotid artery stent [CAS]). STUDY DESIGN:Using the Nationwide Inpatient Sample, crude and propensity-matched rates of the composite end point of stro...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2019.02.054

    authors: Mayor JM,Salemi JL,Dongarwar D,Salihu HM,Montero-Baker M,Mills JL,Chung J

    更新日期:2019-07-01 00:00:00

  • Reduction in Venous Thromboembolism Events: Trauma Performance Improvement and Loop Closure Through Participation in a State-Wide Quality Collaborative.

    abstract:BACKGROUND:The Michigan Trauma Quality Improvement Program (MTQIP) is a collaborative quality initiative sponsored by Blue Cross Blue Shield of Michigan and Blue Care Network (BCBSM/BCN). The MTQIP benchmark reports identified our trauma center as a high outlier for venous thromboembolism (VTE) episodes. This study out...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.05.006

    authors: Machado-Aranda DA,Jakubus JL,Wahl WL,Cherry-Bukowiec JR,To KB,Park PK,Raghavendran K,Napolitano LM,Hemmila MR

    更新日期:2015-09-01 00:00:00

  • Diagnosis and treatment of Mirizzi syndrome: 23-year Mayo Clinic experience.

    abstract:BACKGROUND:Mirizzi syndrome (MS) is characterized by extrinsic compression of the common hepatic duct by stones impacted in the cystic duct or gallbladder neck. Open cholecystectomy (OC) has been the standard treatment; however, laparoscopy has challenged this approach. STUDY DESIGN:The objective of this study was to ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.03.008

    authors: Erben Y,Benavente-Chenhalls LA,Donohue JM,Que FG,Kendrick ML,Reid-Lombardo KM,Farnell MB,Nagorney DM

    更新日期:2011-07-01 00:00:00

  • The potent somatostatin analogue vapreotide does not decrease pancreas-specific complications after elective pancreatectomy: a prospective, multicenter, double-blinded, randomized, placebo-controlled trial.

    abstract:BACKGROUND:Pancreatectomy can be complicated by pancreatic anastomotic leakage, causing major morbidity. STUDY DESIGN:Our aim was to determine if vapreotide, a potent long-acting somatostatin analogue, would decrease pancreas-related complications. This prospective, multicenter, randomized, double-blind, placebo-contr...

    journal_title:Journal of the American College of Surgeons

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/S1072-7515(03)00104-2

    authors: Sarr MG,Pancreatic Surgery Group.

    更新日期:2003-04-01 00:00:00

  • Randomized trial of emergency endoscopic sclerotherapy versus emergency portacaval shunt for acutely bleeding esophageal varices in cirrhosis.

    abstract:BACKGROUND:The mortality rate of bleeding esophageal varices in cirrhosis is highest during the period of acute bleeding. This is a report of a randomized trial that compared endoscopic sclerotherapy (EST) with emergency portacaval shunt (EPCS) in cirrhotic patients with acute variceal hemorrhage. STUDY DESIGN:A total...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jamcollsurg.2009.02.059

    authors: Orloff MJ,Isenberg JI,Wheeler HO,Haynes KS,Jinich-Brook H,Rapier R,Vaida F,Hye RJ

    更新日期:2009-07-01 00:00:00

  • Are surgical trials with negative results being interpreted correctly?

    abstract:BACKGROUND:Many published accounts of clinical trials report no differences between the treatment arms, while being underpowered to find differences. This study determined how the authors of these reports interpreted their findings. STUDY DESIGN:We examined 54 reports of surgical trials chosen randomly from a database...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2012.09.015

    authors: Brody BA,Ashton CM,Liu D,Xiong Y,Yao X,Wray NP

    更新日期:2013-01-01 00:00:00

  • Operating room efficiency and hospital capacity: factors affecting operating room use during maximum hospital census.

    abstract:BACKGROUND:Academic medical centers are faced with increasing volumes, higher acuity, and, as a consequence, capacity issues. These affect operating room (OR) use and patient throughput, with negative impact on finances and patient and physician satisfaction. We evaluated our experiences in dealing with OR efficiency a...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2007.01.052

    authors: McGowan JE,Truwit JD,Cipriano P,Howell RE,VanBree M,Garson A Jr,Hanks JB

    更新日期:2007-05-01 00:00:00

  • Efforts to improve local control in rectal cancer compromise survival by the potential morbidity of optimal mesorectal excision.

    abstract:BACKGROUND:The technique of total mesorectal excision (TME) increases the risk of anastomotic leakage. The impact of postoperative morbidity of TME on longterm survival has never been described. We retrospectively analyzed factors that might influence survival after TME for rectal cancer, including postoperative morbid...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2006.07.021

    authors: Laurent C,Nobili S,Rullier A,Vendrely V,Saric J,Rullier E

    更新日期:2006-11-01 00:00:00

  • Comparative analysis of vagotomy and drainage versus vagotomy and resection procedures for bleeding peptic ulcer disease: results of 907 patients from the Department of Veterans Affairs National Surgical Quality Improvement Program database.

    abstract:BACKGROUND:The purpose of this study was to determine postoperative outcomes and risk factors for morbidity and mortality in patients requiring surgery for bleeding peptic ulcer disease (PUD). Vagotomy and drainage procedures are technically simpler but are usually associated with higher ulcer recurrence rates. In cont...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2005.09.001

    authors: de la Fuente SG,Khuri SF,Schifftner T,Henderson WG,Mantyh CR,Pappas TN

    更新日期:2006-01-01 00:00:00

  • In-hospital mortality after pancreatic resection for chronic pancreatitis: population-based estimates from the nationwide inpatient sample.

    abstract:BACKGROUND:Pancreatic resection can be performed to ameliorate the sequelae of chronic pancreatitis in selected patients. The perceived risk of pancreatectomy may limit its use. Using a national database, this study compared mortality after pancreatic resections for chronic pancreatitis with those performed for neoplas...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2009.05.030

    authors: Hill JS,McPhee JT,Whalen GF,Sullivan ME,Warshaw AL,Tseng JF

    更新日期:2009-10-01 00:00:00

  • Survival of the fittest: the hidden cost of undertriage of major trauma.

    abstract:BACKGROUND:Injured patients cared for in trauma centers have a lower risk of death than those cared for in nontrauma centers. However, many patients are transported to a non-trauma center after injury (undertriaged) and require transfer to trauma center care. Previous analyses of undertriage focused only on survivors t...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2010.08.014

    authors: Haas B,Gomez D,Zagorski B,Stukel TA,Rubenfeld GD,Nathens AB

    更新日期:2010-12-01 00:00:00

  • Complex gastrointestinal surgery: impact of provider experience on clinical and economic outcomes.

    abstract:BACKGROUND:Commonly performed elective gastrointestinal surgical procedures are carried out with low morbidity and mortality in hospitals throughout the United States. Complex operative procedures on the alimentary tract are performed with a relatively low frequency and are associated with higher mortality. Volume and ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(99)00072-1

    authors: Gordon TA,Bowman HM,Bass EB,Lillemoe KD,Yeo CJ,Heitmiller RF,Choti MA,Burleyson GP,Hsieh G,Cameron JL

    更新日期:1999-07-01 00:00:00

  • Developing quality indicators for elderly patients undergoing abdominal operations.

    abstract:BACKGROUND:Although the expanding and aging population will likely increase demand for surgical services, surgeons and other providers must develop strategies to optimize care. We sought to develop process-based quality indicators for elderly patients undergoing abdominal operations to identify necessary and meaningful...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2005.07.009

    authors: McGory ML,Shekelle PG,Rubenstein LZ,Fink A,Ko CY

    更新日期:2005-12-01 00:00:00

  • Learning Curve for Surgeons Adopting Transcarotid Artery Revascularization Based on the Vascular Quality Initiative-Transcarotid Artery Revascularization Surveillance Project.

    abstract:BACKGROUND:Transcarotid artery revascularization (TCAR) with flow reversal was recently introduced as a novel technique for carotid artery stenting (CAS). We examined the learning curve of surgeons adopting TCAR based on data from the Vascular Quality Initiative (VQI-TCAR Surveillance Project; TSP). STUDY DESIGN:We id...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2019.09.020

    authors: Kashyap VS,King AH,Liang P,Eldrup-Jorgensen J,Wang GJ,Malas MB,Nolan BW,Cronenwett JL,Schermerhorn ML

    更新日期:2020-01-01 00:00:00

  • Preoperative esophageal cancer staging: magnetic resonance imaging of lymph node with ferumoxtran-10, an ultrasmall superparamagnetic iron oxide.

    abstract:BACKGROUND:Accurate detection of metastasis to lymph nodes is an essential component of the approach to treatment. The purpose of this study was to evaluate the utility of magnetic resonance imaging with ferumoxtran-10 in diagnosing lymph node metastasis in esophageal cancer. STUDY DESIGN:Sixteen patients with esophag...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2005.12.004

    authors: Nishimura H,Tanigawa N,Hiramatsu M,Tatsumi Y,Matsuki M,Narabayashi I

    更新日期:2006-04-01 00:00:00

  • Portal vein resection in borderline resectable pancreatic cancer: a United Kingdom multicenter study.

    abstract:BACKGROUND:Until recently, in the United Kingdom, borderline resectable pancreatic cancer with invasion into the portomesenteric veins often resulted in surgical bypass because of the presumed high risk for complications and the uncertainty of a survival benefit associated with a vascular resection. Portomesenteric vei...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2013.11.017

    authors: Ravikumar R,Sabin C,Abu Hilal M,Bramhall S,White S,Wigmore S,Imber CJ,Fusai G,UK Vascular Resection in Pancreatic Cancer Study Group.

    更新日期:2014-03-01 00:00:00

  • The longitudinal study of surgical residents, 1994 to 1996.

    abstract:BACKGROUND:The American College of Surgeons (ACS) has conducted a detailed annual survey of residents enrolled in surgical graduate medical education (GME) programs since 1982 and has regularly published the resulting data as the Longitudinal Study of Surgical Residents. This report documents surgical resident enrollme...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(99)00044-7

    authors: Kwakwa F,Jonasson O

    更新日期:1999-06-01 00:00:00

  • Impact of the COVID-19 Pandemic on Lung Cancer Screening Program and Subsequent Lung Cancer.

    abstract:BACKGROUND:Low-dose CT (LDCT) screening reduces lung cancer mortality by at least 20%. The COVID-19 pandemic required an unprecedented shutdown in our institutional LDCT program. The purpose of this study was to examine the impact of COVID-19 on lung cancer screening and subsequent cancer diagnosis. STUDY DESIGN:We an...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2020.12.002

    authors: Van Haren RM,Delman AM,Turner KM,Waits B,Hemingway M,Shah SA,Starnes SL

    更新日期:2020-12-17 00:00:00

  • Oral calcium supplements to enhance early hospital discharge after bilateral surgical treatment of the thyroid gland or exploration of the parathyroid glands.

    abstract::One hundred and seventy consecutive patients undergoing parathyroid gland exploration and bilateral thyroidectomy received, postoperatively, routine oral calcium supplementation, close monitoring of total serum calcium, and addition of vitamin D for specific criteria, all to accomplish a postoperative course free of s...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Moore FD Jr

    更新日期:1994-01-01 00:00:00

  • What are the real rates of postoperative complications: elucidating inconsistencies between administrative and clinical data sources.

    abstract:BACKGROUND:Comparison of quality outcomes generated from administrative and clinical datasets have shown inconsistencies. Understanding this is important because data designed to drive performance improvement are used for public reporting of performance. We examined administrative and clinical data and 2 clinical data ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.12.037

    authors: Koch CG,Li L,Hixson E,Tang A,Phillips S,Henderson JM

    更新日期:2012-05-01 00:00:00

  • Open vs Closed Negative Pressure Wound Therapy for Contaminated and Dirty Surgical Wounds: A Prospective Randomized Comparison.

    abstract:BACKGROUND:A new proprietary negative pressure wound device has been developed to apply negative pressure therapy to closed wounds (closed-NPWT). We postulated that closed-NPWT management of contaminated and dirty wounds would lead to faster wound healing and no significant difference in wound complications. STUDY DES...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jamcollsurg.2017.12.008

    authors: Frazee R,Manning A,Abernathy S,Isbell C,Isbell T,Kurek S,Regner J,Smith R,Papaconstantinou H

    更新日期:2018-04-01 00:00:00

  • The impact of complications on outcomes after resection for esophageal and gastroesophageal junction carcinoma.

    abstract:BACKGROUND:Efforts to improve surgical outcomes have traditionally focused on improving preoperative patient selection and reducing the risk of postoperative medical complications. Strategies to optimize surgical technique have been less well studied. We sought to assess the relation between complications related to su...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2003.08.007

    authors: Rizk NP,Bach PB,Schrag D,Bains MS,Turnbull AD,Karpeh M,Brennan MF,Rusch VW

    更新日期:2004-01-01 00:00:00

  • A technique of direct percutaneous jejunostomy tube placement.

    abstract::A technique for replacement of a feeding jejunostomy tube using endoscopic direct visualization is described herein. It can be used in patients who have had a previously placed open jejunostomy tube removed after recovery from resection of the gastrointestinal tract. This is accomplished quite easily using local anest...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Pritchard TJ,Bloom AD

    更新日期:1994-02-01 00:00:00

  • Objective comparison of complications resulting from laparoscopic bariatric procedures.

    abstract:BACKGROUND:Several surgical treatment options for morbid obesity exist. Currently, there are no studies that objectively compare complication rates after laparoscopic bariatric operations performed at a single institution. We objectively classify and compare complications resulting from laparoscopic adjustable gastric ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2005.10.003

    authors: Parikh MS,Laker S,Weiner M,Hajiseyedjavadi O,Ren CJ

    更新日期:2006-02-01 00:00:00

  • Influence of Cold Ischemia Time in Combination with Donor Acute Kidney Injury on Kidney Transplantation Outcomes.

    abstract:BACKGROUND:Deceased-donor kidneys are often exposed to ischemic events from donor instability, as evidenced by acute kidney injury (AKI). Clinicians may be reluctant to transplant kidneys with AKI that also have prolonged cold ischemia time (CIT) for fear of an additional deleterious effect. STUDY DESIGN:We evaluated ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.05.003

    authors: Xia Y,Friedmann P,Cortes CM,Lubetzky ML,Kayler LK

    更新日期:2015-08-01 00:00:00

  • Longterm followup assessment of a HER2/neu peptide (E75) vaccine for prevention of recurrence in high-risk prostate cancer patients.

    abstract:BACKGROUND:E75 is an immunogenic peptide from the HER2/neu protein that is expressed in prostate cancer. High-risk prostate cancer (HRPC) patients demonstrating varying levels of HER2/neu expression were vaccinated with E75 peptide plus granulocyte-macrophage colony-stimulating factor to prevent postprostatectomy PSA a...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2008.10.018

    authors: Gates JD,Carmichael MG,Benavides LC,Holmes JP,Hueman MT,Woll MM,Ioannides CG,Robson CH,McLeod DG,Ponniah S,Peoples GE

    更新日期:2009-02-01 00:00:00

  • Retained surgical items: a problem yet to be solved.

    abstract:BACKGROUND:Retained surgical items (RSI) continue to occur. Large RSI studies are few due to low RSI frequency in single institutions and the medicolegal implications. Consequently, RSI risks are not fully defined, with discrepancies persisting among published studies. The goals of this study were to better define risk...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2012.08.026

    authors: Stawicki SP,Moffatt-Bruce SD,Ahmed HM,Anderson HL 3rd,Balija TM,Bernescu I,Chan L,Chowayou L,Cipolla J,Coyle SM,Gracias VH,Gunter OL,Marchigiani R,Martin ND,Patel J,Seamon MJ,Vagedes E,Ellison EC,Steinberg SM,Cook C

    更新日期:2013-01-01 00:00:00

  • Body mass index and outcomes in critically injured blunt trauma patients: weighing the impact.

    abstract:BACKGROUND:The influence of increased body mass index (BMI) on morbidity and mortality in critically injured trauma patients has been studied, with conflicting results. The objective of this study was to investigate the relationship between stratified BMI and outcomes in blunt injured patients. STUDY DESIGN:Consecutiv...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2006.12.042

    authors: Newell MA,Bard MR,Goettler CE,Toschlog EA,Schenarts PJ,Sagraves SG,Holbert D,Pories WJ,Rotondo MF

    更新日期:2007-05-01 00:00:00