Abstract:
:One hundred patients with suspected acute abdominal inflammation were imaged at 0.5, 2-3, 4-6, and 24 hours after the administration of Tc-99m HMPAO labeled autologous leukocytes. Scan findings were retrospectively compared with final diagnosis, serum C-reactive protein (CRP), and antibiotic treatment. Clinical findings were confirmed with surgery, barium enema, or sigmoidoscopy in 61 patients, and diagnosis was based only on clinical findings in 13 patients. In 26 patients, symptoms subsided before a final diagnosis was made. Tc-99m leukocyte images were positive in 45 of the 61 patients with a confirmed diagnosis, including all patients with acute cholecystitis (N = 4) and inflammatory bowel disease (N = 8). They were also positive in nineteen out of 25 patients who had acute colonic diverticulitis and in 6 out of 7 who had intra-abdominal abscesses. Abnormal activity was found in patients with colonic carcinoma, small bowel infarction, and acute appendicitis. Abnormal activity was visualized in 0.5-hour images in all but one of the positive cases. With the exception of two postoperative cases, malignant lymphoma, and a liver abscess, a CRP level of greater than 75 mg/L was associated with positive image findings. Antibiotic treatment did not affect imaging findings. Imaging with Tc-99m labeled leukocytes appears to be valuable for detecting and localizing abdominal inflammation, and three-phase imaging during the first 4-6 hours is recommended. In some cases, 24-hour images may be useful for distinguishing small bowel from large bowel inflammation.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Laitinen R,Tähtinen J,Lantto T,Vorne Mdoi
10.1097/00003072-199009000-00001subject
Has Abstractpub_date
1990-09-01 00:00:00pages
597-602issue
9eissn
0363-9762issn
1536-0229journal_volume
15pub_type
杂志文章abstract::Hepatic pyocyst is a rare but potentially life-threatening complication of autosomal dominant polycystic kidney disease. With extensive hepatic cystic disease, localization of a pyocyst and targeted aspiration or drainage is often a diagnostic challenge. Two patients with autosomal dominant polycystic kidney disease a...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000402
更新日期:2014-07-01 00:00:00
abstract:PURPOSE:Technetium-99m pertechnetate scintigraphy is a well-established technique for diagnosing congenital hypothyroid disease. However, the biodistribution of pertechnetate (TcO4-) in neonates and young infants is not well documented. The purpose of this study was to analyze and document the biodistribution of TcO4- ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200104000-00006
更新日期:2001-04-01 00:00:00
abstract::Two case reports of malignant pleural effusion from breast carcinoma, with scans showing a striking accumulation of Tc-99m MDP, are presented. The Tc-99m MDP was in the pleural fluid and not in the pleura as demonstrated by shift with gravity. Possible mechanisms of malignant effusion accumulation of Tc-99m MDP are su...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198207000-00009
更新日期:1982-07-01 00:00:00
abstract::Tc-99m hexamethylpropylene amineoxime (HMPAO) is a novel radiopharmaceutical demonstrated to be a sensitive indicator of abnormalities of cerebral perfusion. Most reports in the literature have evaluated patients with gross perfusion deficits, such as cerebrovascular accidents, and with dementia, where patterns of dif...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199103000-00007
更新日期:1991-03-01 00:00:00
abstract::Double-inlet left ventricle (DILV) is a congenital heart disease that only a single left ventricle and a rudimentary right ventricle are developed. Because of lack of anatomic landmark, interpretation of Tl myocardial perfusion imaging in DILV is essentially challenging for unusual anomaly. We report the case of a 44-...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001961
更新日期:2018-03-01 00:00:00
abstract:PURPOSE OF THE REPORT:Autonomous functioning thyroid nodules (AFTN), defined as "hot nodules" at thyroid scan, are often cured by radioiodine treatment. The aim of our study was to investigate the long-term outcome in patients treated with an 131I calculated dose, to identify a possible "size-tailored" dose, and to sim...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318286bbda
更新日期:2013-05-01 00:00:00
abstract::Pituitary macroadenoma constitutes a frequently misdiagnosed benign tumor. We report herein a case where such macroadenoma, a prolactinoma, was incidentally discovered in a 63-year-old man who had been referred to F-FDG PET and F-FDOPA PET imaging for a pharmacoresistant epilepsy. An increased uptake was documented fo...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001721
更新日期:2017-08-01 00:00:00
abstract::Various etiologies could cause focal I accumulation. Hepatic cyst is one of these etiologies. Here we present a 59-year-old man with a history of papillary thyroid cancer resection who received radioiodine therapy for three times. The images after the I therapy of the second and third time showed variable activity upt...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002442
更新日期:2019-04-01 00:00:00
abstract::A 72-year-old man with a history of prostate adenocarcinoma initially managed by radical prostatectomy and salvage radiation therapy underwent resection of a left vas deferens recurrence identified on PSMA PET. Despite an initial response, PSA failed to fall below 3.5 ng/L, prompting re-evaluation with PSMA PET/CT: a ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003136
更新日期:2020-09-01 00:00:00
abstract::We present a case of a 55-year-old man with a history of poorly differentiated metastatic thyroid cancer, which is rare and shows aggressive behavior. The patient had radioactive iodine-negative multiple metastasis on F-FDGPET/CT, therefore Ga-DOTATATE and Ga-PSMA PET/CT were performed whether an opportunity exist for...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003362
更新日期:2020-11-03 00:00:00
abstract::An automated volume determination program using SPECT imaging with Tc-99m has been validated by both phantom and patient studies. Its use for monitoring change of function of the liver and change in tumor mass during different therapy regimes has been assessed. The technique is not restricted to the estimation of the ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199007000-00009
更新日期:1990-07-01 00:00:00
abstract::We report on a 45-year-old man who had a mass on the wall of the anterior right hemithorax. An excisional biopsy indicated carcinoma metastasis from thyroid malignancy. Tc-99m methoxyisobutyl isonitrile (MIBI) scintigraphy revealed markedly increased activity on the left side of the thyroid and the thoracic wall mass....
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181813035
更新日期:2008-09-01 00:00:00
abstract::On In-111 WBC images, diffuse homogeneous uptake of the radiopharmaceutical should be present throughout the liver. The authors present a case of a febrile patient with polycystic liver disease in whom the normal diffuse uptake was not seen. Instead, the images demonstrated focal areas of uptake, which suggested infec...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199311000-00009
更新日期:1993-11-01 00:00:00
abstract::The Dandy-Walker syndrome (DWS) is a rare congenital posterior fossa malformation characterized by aplasia or hypoplasia of the cerebellar vermis, cystic dilatation of the fourth ventricle, and enlargement of the posterior fossa. We present a 52-year-old Caucasian man diagnosed with gastrointestinal stromal tumor and ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000871
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to evaluate the efficacy of ¹⁸F-choline PET/CT (18FCH-PET/CT) in restaging patients previously treated by radical prostatectomy for a prostate cancer, presenting with biochemical relapse during follow-up (FU). PATIENTS AND METHODS:Three hundred thirty-one patients referred to us from ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318266cc38
更新日期:2013-01-01 00:00:00
abstract::In-111 leukocyte imaging usually yields images which are interpreted easily. Five potentially misleading cases were noted, however, of over 200 scans performed over a four-year period. These included two cases of bladder visualization without bladder inflammation and three cases of abdominal activity without intra-abd...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198606000-00004
更新日期:1986-06-01 00:00:00
abstract:PURPOSE:To define the appropriate scan time for fluorine-18-labeled dihydroxyphenylalanine (F-18 DOPA) PET in oncological imaging of pheochromocytomas and paragangliomas. MATERIALS AND METHODS:F-18 DOPA PET examinations were performed in 9 patients with 7 pheochromocytomas and 4 head and neck paragangliomas using a de...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318238f550
更新日期:2012-02-01 00:00:00
abstract::A 5-year-old girl with fever and tenderness in her left wrist and right ankle was hospitalized. Bone scanning and Tc-99m labeled leukocyte imaging showed increased uptake in these joints and also in her left knee. These radionuclide methods helped determine the diagnosis and were superior to plain radiography and CT s...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199012000-00007
更新日期:1990-12-01 00:00:00
abstract::A 10-year-old girl with a history of complicated cystic fibrosis was hospitalized for pulmonary exacerbation with allergic bronchopulmonary aspergillosis and severe right upper lobe bronchiectasis diagnosed with chest radiograph and CT. She was started on itraconazole during the hospitalization in attempt to decrease ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002264
更新日期:2018-11-01 00:00:00
abstract::Perfusion lung scintigraphy using SPECT/CT is one mainstay in diagnosing pulmonary embolism. Although typically almost all tracer will be accumulated in the lung capillaries, occasionally abnormal uptake can be detected. As superior vena cava syndrome leads to aberrant blood flow, tracer injected to an arm vein might ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003127
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:Tl-201 chloride has been used to image viable tumors in various sites of the body. There has been limited use of Tl-201 below the diaphragm because of normal uptake in the liver, spleen, kidneys, and intestines. The use of sequential Tl-201 and Tc-99m sulfur colloid in the detection and characterization of susp...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199612000-00007
更新日期:1996-12-01 00:00:00
abstract::Hepatobiliary studies were performed over a three-year period on 139 patients suspected of having cystic duct obstruction. Each patient was infused intravenously with sincalide, a C-terminal octapeptide of CCK, 15 minutes prior to the administration of the hepatobiliary imaging agent Tc-99m paraisopropyl iminodiacetic...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198505000-00003
更新日期:1985-05-01 00:00:00
abstract::In addition to imaging in the conventional positions, TI-201 myocardial imaging was also performed in a 25 degree cephalad projection. This resulted in improved imaging, especially of the inferior wall. Myocardial images are presented in five patients in whom areas of absent activity were most sharply delineated in th...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198105000-00009
更新日期:1981-05-01 00:00:00
abstract::A 60-year-old woman with clinical and biochemical features suggestive of adrenal insufficiency was found to have bilateral adrenal masses on CT scan and was subjected to F-FDG PET scan. The scan showed hypermetabolic mediastinal nodes in addition to intense tracer uptake in bilateral adrenal masses. CT-guided adrenal ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000400
更新日期:2014-06-01 00:00:00
abstract::A 73-year-old man with chronic obstructive pulmonary disease and no known malignancies was evaluated for back pain. MR examination showed lumbar spine compression fractures, and an F-FDG PET/CT scan was requested to assess for skeletal metastatic disease and potential detection of a primary neoplasm. The PET/CT examin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003154
更新日期:2020-08-01 00:00:00
abstract::We describe the utility of molecular imaging with F-FDG and Ga-DOTANOC PET for treatment response assessment in a case of metastatic medulloblastoma. F-FDG and Ga-DOTANOC PET/CT revealed extensive metastases to bone and bone marrow. Patient subsequently had an excellent response to systemic chemotherapy which was evid...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003435
更新日期:2020-12-07 00:00:00
abstract::Myocardial perfusion imaging with Tc-99m carbomethoxyisopropylisonitrile (CPI) was compared with Tl-201 imaging in 22 patients who were assessed for coronary artery disease. There was agreement between Tc-99m CPI and Tl-201 imaging for detecting segmental myocardial ischemia and fixed defects in 185/198 (93%) of left ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198709000-00001
更新日期:1987-09-01 00:00:00
abstract::A 43-year-old woman presented with numbness of the left hand and leg for 4 weeks. MRI of the spinal cord revealed an intramedullary lesion with central nodular enhancement at the C3 level. Primary tumor or metastasis of the cervical spinal cord was suspected. FDG PET/CT showed focal hypermetabolism of the spinal cord ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000003287
更新日期:2020-12-01 00:00:00
abstract::In a patient with AIDS, marked uptake of Ga-67 in the stomach walls initially was regarded with a high degree of suspicion for gastric involvement. Results of subsequent intragastric tests, including biopsy and culture, proved negative. Caution should be exercised when considering further costly and/or invasive proced...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198602000-00015
更新日期:1986-02-01 00:00:00
abstract::Takayasu's disease (pulseless disease) is an uncommon chronic inflammatory disease primarily affecting the medium and large arteries, with a strong predilection for the aortic arch and its branches; hence, it sometimes is referred to as aortic arch syndrome. The etiology is unknown, although a systemic immunologic pro...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199309000-00002
更新日期:1993-09-01 00:00:00