Remifentanil-propofol sedation as an ambulatory anesthesia for carpal tunnel release.

Abstract:

OBJECTIVE:This prospective study evaluated the use of continuous sedation using propofol and remifentanil when carpal tunnel release (CTR) was performed under local anesthesia. METHODS:We sedated 60 patients undergoing CTR using local anesthesia with remifentanil at loading and continuous doses of 0.5 µg kg(-1) and 0.05 µg kg(-1)min(-1), respectively, and propofol, using a target controlled infusion (TCI) pump set to a target of 2 µg mL(-1) (group A), or with the same drug doses except that the continuous remifentanil dose was 0.07 µg kg(-1)min(-1) (group B) or 0.1 µg kg(-1)min(-1) (group C). RESULTS:In group B, the levels of pain when local anesthetics were administered (p = 0.001), intraoperative pain (p < 0.001) and anxiety (p = 0.001) were significantly lower than those of group A. Furthermore, the incidence of adverse events, including desaturation (p < 0.001) and vomiting (p = 0.043), was significantly lower in group B than in group C. CONCLUSION:Continuous sedation using an appropriate dose of remifentanil and propofol can be used as safe, efficacious ambulatory anesthesia in cases of CTR under local anesthesia, performed using only 2 mL of local anesthetic, with a high degree of patient satisfaction.

journal_name

J Korean Neurosurg Soc

authors

Lee JJ,Hwang SM,Jang JS,Lim SY,Heo DH,Cho YJ

doi

10.3340/jkns.2010.48.5.429

subject

Has Abstract

pub_date

2010-11-01 00:00:00

pages

429-33

issue

5

eissn

2005-3711

issn

1598-7876

journal_volume

48

pub_type

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