Imprinted genes show unique patterns of sequence conservation.

abstract：BACKGROUND:The orders Ascaridida, Oxyurida, and Spirurida represent major components of zooparasitic nematode diversity, including many species of veterinary and medical importance. Phylum-wide nematode phylogenetic hypotheses have mainly been based on nuclear rDNA sequences, but more recently complete mitochondrial (m...

journal_title：BMC genomics

authors： Park JK,Sultana T,Lee SH,Kang S,Kim HK,Min GS,Eom KS,Nadler SA

更新日期：2011-08-03 00:00:00

abstract：BACKGROUND:Inadvertent sample swaps are a real threat to data quality in any medium to large scale omics studies. While matches between samples from the same individual can in principle be identified from a few well characterized single nucleotide polymorphisms (SNPs), omics data types often only provide low to moderat...

journal_title：BMC genomics

authors： Westphal M,Frankhouser D,Sonzone C,Shields PG,Yan P,Bundschuh R

更新日期：2019-12-30 00:00:00

abstract：BACKGROUND:Colletotrichum graminicola and C. sublineola cause anthracnose leaf and stalk diseases of maize and sorghum, respectively. In spite of their close evolutionary relationship, the two species are completely host-specific. Host specificity is often attributed to pathogen virulence factors, including specialized...

journal_title：BMC genomics

authors： Buiate EAS,Xavier KV,Moore N,Torres MF,Farman ML,Schardl CL,Vaillancourt LJ

更新日期：2017-01-10 00:00:00

abstract：BACKGROUND:Major secondary metabolites, including flavonoids, caffeine, and theanine, are important components of tea products and are closely related to the taste, flavor, and health benefits of tea. Secondary metabolite biosynthesis in Camellia sinensis is differentially regulated in different tissues during growth a...

journal_title：BMC genomics

authors： Li CF,Zhu Y,Yu Y,Zhao QY,Wang SJ,Wang XC,Yao MZ,Luo D,Li X,Chen L,Yang YJ

更新日期：2015-07-29 00:00:00

abstract：BACKGROUND:Of the hundreds of Vibrio cholerae serogroups, O1 and O139 are the main epidemic-causing ones. Although non-O1/non-O139 serogroups rarely cause epidemics, the possibility exists for strains within them to have pathogenic potential. RESULTS:We selected 25 representative strains within 16 V. cholerae serogrou...

journal_title：BMC genomics

authors： Li Z,Lu X,Wang D,Liang WL,Zhang J,Li J,Xu J,Pang B,Kan B

更新日期：2019-03-25 00:00:00

abstract：BACKGROUND:Mitochondria are organelles that fulfill a fundamental role in cell bioenergetics, as well as in other processes like cell signaling and death. Small non-coding RNAs (sncRNA) are now being considered as pivotal post-transcriptional regulators, widening the landscape of their diversity and functions. In mamma...

journal_title：BMC genomics

authors： Larriba E,Rial E,Del Mazo J

更新日期：2018-08-28 00:00:00

abstract：BACKGROUND:Ancestry informative markers (AIMs) are a type of genetic marker that is informative for tracing the ancestral ethnicity of individuals. Application of AIMs has gained substantial attention in population genetics, forensic sciences, and medical genetics. Single nucleotide polymorphisms (SNPs), the materials ...

journal_title：BMC genomics

authors： Yang HC,Wang PL,Lin CW,Chen CH,Chen CH

更新日期：2012-07-28 00:00:00

abstract：BACKGROUND:During the evolution of mammalian sex chromosomes, the degeneration of Y-linked homologs has led to a dosage imbalance between X-linked and autosomal genes. The evolutionary resolution to such dosage imbalance, as hypothesized by Susumu Ohno fifty years ago, should be doubling the expression of X-linked gene...

journal_title：BMC genomics

authors： Yang JR,Chen X

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:For their transmission, African trypanosomes rely on their blood feeding insect vector, the tsetse fly (Glossina sp.). The ingested Trypanosoma brucei parasites have to overcome a series of barriers in the tsetse fly alimentary tract to finally develop into the infective metacyclic forms in the salivary glan...

journal_title：BMC genomics

authors： Matetovici I,Caljon G,Van Den Abbeele J

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Studying functional divergences between paralogs that originated from genome duplication is a significant topic in investigating molecular evolution. Genes that exhibit basal level cyclic expression patterns including circadian and light responsive genes are important physiological regulators. Temporal shift...

journal_title：BMC genomics

authors： Lu Y,Boswell M,Boswell W,Salinas RY,Savage M,Reyes J,Walter S,Marks R,Gonzalez T,Medrano G,Warren WC,Schartl M,Walter RB

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:Genome rearrangement describes gross changes of chromosomal regions, plays an important role in evolutionary biology and has profound impacts on phenotype in organisms ranging from microbes to humans. With more and more complete genomes accomplished, lots of genomic comparisons have been conducted in order t...

journal_title：BMC genomics

authors： Wang D,Li S,Guo F,Ning K,Wang L

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Archived formalin fixed paraffin embedded (FFPE) samples are valuable clinical resources to examine clinically relevant morphology features and also to study genetic changes. However, DNA quality and quantity of FFPE samples are often sub-optimal, and resulting NGS-based genetics variant detections are prone...

journal_title：BMC genomics

authors： Bhagwate AV,Liu Y,Winham SJ,McDonough SJ,Stallings-Mann ML,Heinzen EP,Davila JI,Vierkant RA,Hoskin TL,Frost M,Carter JM,Radisky DC,Cunningham JM,Degnim AC,Wang C

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:Many bacterial chromosomes display nucleotide asymmetry, or skew, between the leading and lagging strands of replication. Mutational differences between these strands result in an overall pattern of skew that is centered about the origin of replication. Such a pattern could also arise from selection coupled ...

journal_title：BMC genomics

authors： Morton RA,Morton BR

更新日期：2007-10-12 00:00:00

abstract：BACKGROUND:Histone H3 lysine 4 tri-methylation (H3K4me3) and histone H3 lysine 9 tri-methylation (H3K9me3) are widely perceived to be opposing and often mutually exclusive chromatin modifications. However, both are needed for certain light-activated genes in Neurospora crassa (Neurospora), including frequency (frq) and...

journal_title：BMC genomics

authors： Zhu Q,Ramakrishnan M,Park J,Belden WJ

更新日期：2019-05-08 00:00:00

abstract：BACKGROUND:As ectothermic organisms have evolved to differing aquatic climates, the molecular basis of thermal adaptation is a key area of research. In this study, we tested for differential transcriptional response of ecologically divergent populations of redband trout (Oncorhynchus mykiss gairdneri) that have evolved...

journal_title：BMC genomics

authors： Narum SR,Campbell NR

更新日期：2015-02-21 00:00:00

abstract：BACKGROUND:Butterflies and moths are emerging as model organisms in genetics and evolutionary studies. The family Hesperiidae (skippers) was traditionally viewed as a sister to other butterflies based on its moth-like morphology and darting flight habits with fast wing beats. However, DNA studies suggest that the famil...

journal_title：BMC genomics

authors： Cong Q,Borek D,Otwinowski Z,Grishin NV

更新日期：2015-08-27 00:00:00

abstract：BACKGROUND:Whilst being closely related to the model actinomycete Streptomyces coelicolor A3(2), S. lividans 66 differs from it in several significant and phenotypically observable ways, including antibiotic production. Previous comparative gene hybridization studies investigating such differences have used low-density...

journal_title：BMC genomics

authors： Lewis RA,Laing E,Allenby N,Bucca G,Brenner V,Harrison M,Kierzek AM,Smith CP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Spinal cord injury leads to neurological dysfunctions affecting the motor, sensory as well as the autonomic systems. Increased excitability of motor neurons has been implicated in injury-induced spasticity, where the reappearance of self-sustained plateau potentials in the absence of modulatory inputs from t...

journal_title：BMC genomics

authors： Ryge J,Winther O,Wienecke J,Sandelin A,Westerdahl AC,Hultborn H,Kiehn O

更新日期：2010-06-09 00:00:00

abstract：BACKGROUND:Embryonic and fetal exposure to maternal obesity causes several maladaptive morphological and epigenetic changes in exposed offspring. The timing of these events is unclear, but changes can be observed even after a short exposure to maternal obesity around the time of conception. The hypothesis of this work ...

journal_title：BMC genomics

authors： McCoski SR,Vailes MT,Owens CE,Cockrum RR,Ealy AD

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:Compromised intestinal barrier (CIB) has been associated with many enteropathies, including colorectal cancer (CRC) and inflammatory bowel disease (IBD). We hypothesized that CIB could lead to increased host-derived contents including epithelial cells into the gut, change its physio-metabolic properties, and...

journal_title：BMC genomics

authors： Jiang P,Lai S,Wu S,Zhao XM,Chen WH

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:We previously described the first respiratory Saccharomyces cerevisiae strain, KOY.TM6*P, by integrating the gene encoding a chimeric hexose transporter, Tm6*, into the genome of an hxt null yeast. Subsequently we transferred this respiratory phenotype in the presence of up to 50 g/L glucose to a yeast strai...

journal_title：BMC genomics

authors： Bonander N,Ferndahl C,Mostad P,Wilks MD,Chang C,Showe L,Gustafsson L,Larsson C,Bill RM

更新日期：2008-07-31 00:00:00

abstract：BACKGROUND:Protein structure comparison and classification is an effective method for exploring protein structure-function relations. This problem is computationally challenging. Many different computational approaches for protein structure comparison apply the secondary structure elements (SSEs) representation of prot...

journal_title：BMC genomics

authors： Ashby C,Johnson D,Walker K,Kanj IA,Xia G,Huang X

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:While increasing data on bacterial evolution in controlled environments are available, our understanding of bacterial genome evolution in natural environments is limited. We thus performed full genome analyses on four Listeria monocytogenes, including human and food isolates from both a 1988 case of sporadic...

journal_title：BMC genomics

authors： Orsi RH,Borowsky ML,Lauer P,Young SK,Nusbaum C,Galagan JE,Birren BW,Ivy RA,Sun Q,Graves LM,Swaminathan B,Wiedmann M

更新日期：2008-11-13 00:00:00

abstract：BACKGROUND:Escherichia coli infections known as colibacillosis constitute a considerable challenge to poultry farmers worldwide, in terms of decreased animal welfare and production economy. Colibacillosis is caused by avian pathogenic E. coli (APEC). APEC strains are extraintestinal pathogenic E. coli and have in gener...

journal_title：BMC genomics

authors： Ronco T,Stegger M,Olsen RH,Sekse C,Nordstoga AB,Pohjanvirta T,Lilje B,Lyhs U,Andersen PS,Pedersen K

更新日期：2017-01-03 00:00:00

abstract：BACKGROUND:Approximately 11 Mb of finished high quality genomic sequences were sampled from cattle, dog and human to estimate genomic divergences and their regional variation among these lineages. RESULTS:Optimal three-way multi-species global sequence alignments for 84 cattle clones or loci (each >50 kb of genomic se...

journal_title：BMC genomics

authors： Liu GE,Matukumalli LK,Sonstegard TS,Shade LL,Van Tassell CP

更新日期：2006-06-07 00:00:00

abstract：BACKGROUND:Cyanobacteria are major primary producers in extreme cold ecosystems. Many lineages of cyanobacteria thrive in these harsh environments, but it is not fully understood how they survive in these conditions and whether they have evolved specific mechanisms of cold adaptation. Phormidesmis priestleyi is a cyano...

journal_title：BMC genomics

authors： Chrismas NA,Barker G,Anesio AM,Sánchez-Baracaldo P

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:The Bacillus cereus sensu lato group consists of six species (B. anthracis, B. cereus, B. mycoides, B. pseudomycoides, B. thuringiensis, and B. weihenstephanensis). While classical microbial taxonomy proposed these organisms as distinct species, newer molecular phylogenies and comparative genome sequencing s...

journal_title：BMC genomics

authors： Schmidt TR,Scott EJ 2nd,Dyer DW

更新日期：2011-08-24 00:00:00

abstract：BACKGROUND:Improving fiber quality is a major challenge in cotton breeding, since the molecular basis of fiber quality traits is poorly understood. Fine mapping and candidate gene prediction of quantitative trait loci (QTL) controlling cotton fiber quality traits can help to elucidate the molecular basis of fiber quali...

journal_title：BMC genomics

authors： Liu D,Zhang J,Liu X,Wang W,Liu D,Teng Z,Fang X,Tan Z,Tang S,Yang J,Zhong J,Zhang Z

更新日期：2016-04-19 00:00:00

abstract：BACKGROUND:Sugarcane is an economically important crop contributing about 80% and 40% to the world sugar and ethanol production, respectively. The complicated genetics consequential to its complex polyploid genome, however, have impeded efforts to improve sugar yield and related important agronomic traits. Modern sugar...

journal_title：BMC genomics

authors： Zhang J,Arro J,Chen Y,Ming R

更新日期：2013-05-10 00:00:00

abstract：BACKGROUND:Despite the known importance of somatic cells for oocyte developmental competence acquisition, the overall mechanisms underlying the acquisition of full developmental competence are far from being understood, especially in non-mammalian species. The present work aimed at identifying key molecular signals fro...

journal_title：BMC genomics

authors： Charlier C,Montfort J,Chabrol O,Brisard D,Nguyen T,Le Cam A,Richard-Parpaillon L,Moreews F,Pontarotti P,Uzbekova S,Chesnel F,Bobe J

更新日期：2012-10-19 00:00:00