Prevalence of atrophic gastritis in dyspeptic patients in Piedmont. A survey using the GastroPanel test.

abstract：BACKGROUND:The study endpoint was to analyze the effect of preanalytical (time, temperature, anticoagulant) and analytical (imprecision, correlation between volume and platelet concentration) variables on mean platelet volume (MPV). A further aim was to calculate in an adult population the reference intervals using the...

journal_title：Clinical chemistry and laboratory medicine

authors： Buttarello M,Mezzapelle G,Plebani M

更新日期：2018-04-25 00:00:00

abstract：BACKGROUND:Whereas N-terminal pro-brain natriuretic peptide (NT-proBNP) is approved for risk stratification of patients with acute coronary syndromes (ACS), short-term temporal changes in NT-proBNP concentrations and the optimal time points for sampling are not clear. The purpose of this study was to better define the ...

journal_title：Clinical chemistry and laboratory medicine

authors： Buchner S,Debl K,Barlage S,Griese D,Fredersdorf S,Jeron A,Lubnow M,Müller T,Muders F,Holmer S,Riegger GA,Luchner A

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:High-density lipoprotein (HDL) is believed to be protective against coronary heart disease (CHD). HDL is comprised of different subfractions. Of these, HDL 2b is believed to be the most important in preventing CHD. Current methods for HDL subfraction measurements are not standardized and often exhibit poor a...

journal_title：Clinical chemistry and laboratory medicine

authors： Yang DH,Konigshofer Y,Dike J,Chang E,Mueller O

更新日期：2010-06-01 00:00:00

abstract：:The acute-phase "panproteinase" inhibitor alpha2-macroglobulin (alpha2M), a protein involved in inflammatory reactions, has been identified in amyloid plaques in Alzheimer's disease (AD). In addition, alpha2M is involved in AD susceptibility at the genetic level, and a deletion polymorphism at the a2M gene has been fo...

journal_title：Clinical chemistry and laboratory medicine

authors： Scacchi R,Ruggeri M,Gambina G,Martini MC,Corbo RM

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:Despite remarkable advances in technology and laboratory automation, results of laboratory testing still suffer from a high degree of preanalytical variability. Although there is no definitive evidence, the use of small-gauge needles for venipuncture is usually discouraged to reduce the chance of producing u...

journal_title：Clinical chemistry and laboratory medicine

authors： Lippi G,Salvagno GL,Montagnana M,Brocco G,Cesare Guidi G

更新日期：2006-01-01 00:00:00

abstract：:Background While quantitation methods for small-molecule and tryptic peptide bottom-up mass spectrometry (MS) have been well defined, quantitation methods for top-down or middle-up MS approaches have not been as well defined. Therapeutic monoclonal antibodies (t-mAbs) are a group of proteins that can be used to both d...

journal_title：Clinical chemistry and laboratory medicine

authors： Cradic KW,Ladwig PM,Rivard AL,Katrangi W,Wintgens KF,Willrich MAV

更新日期：2020-06-25 00:00:00

abstract：BACKGROUND:Urinary enzymes, including the brush border enzyme alanine aminopeptidase (AAP), are reliable biomarkers of nephrotoxicity and represent early indicators of tubular damage. The aim of the present study was to develop and validate an automated urinary AAP activity assay. METHODS AND RESULTS:For this purpose,...

journal_title：Clinical chemistry and laboratory medicine

authors： Holdt B,Peters E,Nagel HR,Steiner M

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Electrospray ionization mass spectrometry (ESI-MS) can be used for the measurement of glycated adult hemoglobin. Here, we describe the evaluation of ESI-MS for measurement of glycated (GHbF) and acetylated (AcHbF) fetal hemoglobin and the identification by mass of different chains of fetal hemoglobin. METHO...

journal_title：Clinical chemistry and laboratory medicine

authors： Davison AS,Green BN,Roberts NB

更新日期：2008-01-01 00:00:00

abstract：:The clinical usefulness of C-reactive protein (CRP) and of transthyretin (TTR) for the early diagnosis and follow-up of infection after an open fracture was prospectively investigated (cohort A). It was complemented by a retrospective study of trauma patients admitted to an intensive care unit (cohort B). Serial deter...

journal_title：Clinical chemistry and laboratory medicine

authors： Férard G,Gaudias J,Bourguignat A,Ingenbleek Y

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Improving quality and patient safety in the medical biochemistry laboratory accredited according to the International Standard Organization (ISO 15189:2012) requires the patient-centered evaluation of errors based on the implementation of quality indicators (QIs) across the total testing process. Our main go...

journal_title：Clinical chemistry and laboratory medicine

authors： Flegar-Meštrić Z,Perkov S,Radeljak A,Kardum Paro MM,Prkačin I,Devčić-Jeras A

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Faecal immunochemical tests (FIT) are becoming widely used in colorectal cancer (CRC) screening. Availability of data on faecal haemoglobin concentrations (f-Hb) in three countries prompted an observational study on sex and age and the transferability of data across geography. METHODS:Single estimates of f-...

journal_title：Clinical chemistry and laboratory medicine

authors： Fraser CG,Rubeca T,Rapi S,Chen LS,Chen HH

更新日期：2014-08-01 00:00:00

abstract：:The discovery and development of new biomarkers continues to be an exciting and promising field. Improvement in prediction of risk of developing disease is one of the key motivations in these pursuits. Appropriate statistical measures are necessary for drawing meaningful conclusions about the clinical usefulness of th...

journal_title：Clinical chemistry and laboratory medicine

authors： Pencina MJ,D'Agostino RB,Vasan RS

更新日期：2010-12-01 00:00:00

abstract：:Since serum and plasma D-dimer concentrations correlate very well, we evaluated the comparability of other haemostasis activation markers in plasma and serum. Prothrombin fragment F1+2, fibrin monomer and D-dimer concentrations were measured with commercially available immunoassays in serum and plasma. Serum to plasma...

journal_title：Clinical chemistry and laboratory medicine

authors： Korte W,Riesen WF

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Although many reports have elucidated pathophysiological characteristics of abnormal bone metabolism in patients with type 2 diabetes mellitus (DT2), determinants of bone mineral density (BMD) in patients with DT2 are still controversial. METHODS:We examined 168 Belarussian men 45-60 years of age. Plasma to...

journal_title：Clinical chemistry and laboratory medicine

authors： Vasilkova O,Mokhort T,Sanec I,Sharshakova T,Hayashida N,Takamura N

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to investigate serum lactate dehydrogenase (LD) levels in patients with silicosis due to denim sandblasting (SDDS) and also to investigate possible correlations between serum LD levels and the degree of radiological extent of disease (RED) and pulmonary function tests. METHO...

journal_title：Clinical chemistry and laboratory medicine

authors： Deniz O,Gumus S,Ors F,Yaman H,Battal B,Karaman B,Acikel CH,Ucar E,Cakir E,Tozkoparan E,Bilgic H

更新日期：2012-01-31 00:00:00

abstract：BACKGROUND:POEMS syndrome is defined by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal gammopathy and Skin changes. The vascular endothelial growth factor (VEGF) appears to play a key role in the pathogenesis of the syndrome, and its concentrations are deemed to correlate to disease activity. The aim of the p...

journal_title：Clinical chemistry and laboratory medicine

authors： Altinier S,Proko K,Zaninotto M,Ciubotaru D,Seguso M,Varagnolo M,Lessi F,Briani C,Adami F,Plebani M

更新日期：2016-06-01 00:00:00

abstract：:Authors are usually invited to follow the instructions to authors in scientific journals, because this section is likely to contain unique requirements, such as the references style requested. Authors not only must accurately check the instructions, but are also expected to verify references against the original docum...

journal_title：Clinical chemistry and laboratory medicine

authors： Salvagno GL,Lippi G,Montagnana M,Guidi GC

更新日期：2008-01-01 00:00:00

abstract：:The proposed recommendation for measuring and reporting chloride in undiluted plasma or blood by ion-selective electrodes (ISEs) will provide results that are identical to chloride concentrations measured by coulometry for standardized normal plasma or blood samples. It is applicable to all current ISEs dedicated to c...

journal_title：Clinical chemistry and laboratory medicine

authors： Rayana MC,Burnett RW,Covington AK,D'Orazio P,Fogh-Andersen N,Jacobs E,Kataky R,Külpmann WR,Kuwa K,Larsson L,Lewenstam A,Maas AH,Mager G,Naskalski JW,Okorodudu AO,Ritter C,St John A,International Federation of Clinical C

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:Knowledge of the fatty acid composition of lipid classes in human plasma is an important factor in the investigation of human metabolism. Therefore, a method for the analysis of neutral lipid (NL), phospholipid (PL) and free fatty acids (FFA) in human plasma has been developed and validated. METHODS:Separat...

journal_title：Clinical chemistry and laboratory medicine

authors： Firl N,Kienberger H,Hauser T,Rychlik M

更新日期：2013-04-01 00:00:00

abstract：:Overcrowding of the emergency department (ED) is rapidly becoming a global challenge and a major source of concern for emergency physicians. The evaluation of cardiac biomarkers is critical for confirming diagnoses and expediting treatment decisions to reduce overcrowding, however, physicians currently face the dilemm...

journal_title：Clinical chemistry and laboratory medicine

authors： Di Somma S,Zampini G,Vetrone F,Soto-Ruiz KM,Magrini L,Cardelli P,Ronco C,Maisel A,Peacock FW

更新日期：2014-10-01 00:00:00

abstract：:An alcohol-associated change in the serum transferrin glycoform pattern, carbohydrate-deficient transferrin (CDT), is used as a biomarker of chronic moderate to heavy alcohol consumption. A current limitation in CDT analysis is the lack of standardization, which hampers clinical and analytical comparison between studi...

journal_title：Clinical chemistry and laboratory medicine

authors： Jeppsson JO,Arndt T,Schellenberg F,Wielders JP,Anton RF,Whitfield JB,Helander A,International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Standardization of Carbohydrate-deficient Transferin (IFCC-WG-CDT).

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:There are several methods for calculating serum osmolality, and their accordance with measured osmolality is the subject of controversy. METHODS:The concentrations of sodium, potassium, glucose, blood urea nitrogen (BUN) and osmolalities of 210 serum samples were measured. Two empirical equations were deduc...

journal_title：Clinical chemistry and laboratory medicine

authors： Rasouli M,Kalantari KR

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Elevated plasma total homocysteine is a risk factor for cardiovascular disease (CVD), but the randomized trials of dietary supplementation with B-vitamins to lower homocysteine have not yet provided clear evidence of benefit on vascular risk. METHODS:Cumulative meta-analysis of all randomized trials assessi...

journal_title：Clinical chemistry and laboratory medicine

authors： Clarke R,Armitage J,Lewington S,Collins R,B-Vitamin Treatment Trialists' Collaboration.

更新日期：2007-01-01 00:00:00

abstract：:Although prostate-specific antigen (PSA), or human kallikrein 3, is the most valuable tool available for the diagnosis and management of prostate cancer, as currently used it is insufficiently sensitive and specific for early detection or staging of the malignancy. Many new concepts have been introduced in order to op...

journal_title：Clinical chemistry and laboratory medicine

authors： Daher R,Beaini M

更新日期：1998-09-01 00:00:00

abstract：:Gastric juice is known to have phospholipase A2 catalytic activity. Helicobacter pylori (H. pylori) has been reported to produce phospholipase A2, which is believed to hydrolyse the protective layer of gastric mucosal phospholipids and to promote mucosal damage. The current study aimed at identifying secretory phospho...

journal_title：Clinical chemistry and laboratory medicine

authors： Huhtinen HT,Grönroos JM,Haapamäki MM,Nevalainen TJ

更新日期：1999-01-01 00:00:00

abstract：:Age-related macular degeneration (AMD) is a sight threatening eye disease that affects millions of humans over the age of 65 years. It is considered to be the major cause of irreversible blindness in the elderly population in the developed world. The disease is prevalent in Europe and the United States, which has a la...

journal_title：Clinical chemistry and laboratory medicine

authors： Kokotas H,Grigoriadou M,Petersen MB

更新日期：2011-04-01 00:00:00

abstract：:Asymmetric dimethylarginine (ADMA) is a potent inhibitor of nitric oxide synthase and is regarded as a novel risk factor for cardiovascular disease. The metabolic pathways of ADMA and homocysteine are strongly intertwined. First, during synthesis of ADMA, two equivalents of homocysteine are formed. Second, homocystein...

journal_title：Clinical chemistry and laboratory medicine

authors： Teerlink T

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:A large body of evidence suggests that not only cerebral but also systemic oxidative stress (OxS) might be involved in the pathogenesis of late onset Alzheimer's disease (LOAD) and vascular dementia (VAD), as well as of the prodromal phase of dementia, the so-called mild cognitive impairment (MCI). In the pr...

journal_title：Clinical chemistry and laboratory medicine

authors： Cervellati C,Romani A,Bergamini CM,Bosi C,Sanz JM,Passaro A,Zuliani G

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:The biochemical determination of cardiac natriuretic peptides, primarily brain natriuretic peptide (BNP) and the amino-terminal fragment of its pro-hormone proBNP (NT-proBNP), are reliable tools for diagnosing cardiac disease, establishing prognosis and evaluating the effectiveness of treatment. These biomar...

journal_title：Clinical chemistry and laboratory medicine

authors： Zaninotto M,Mion MM,Di Serio F,Caputo M,Ottomano C,Plebani M

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:The pathogenesis of pre-eclampsia (PE) is incompletely understood. The placenta is considered to play a key role in this disease. Recent research showed that many microRNAs (miRNAs) are expressed in human placenta. Our aim in this study was to determine differential expression of miRNAs in placenta with seve...

journal_title：Clinical chemistry and laboratory medicine

authors： Hu Y,Li P,Hao S,Liu L,Zhao J,Hou Y

更新日期：2009-01-01 00:00:00