Abstract：
BACKGROUND:Clinical recognition of acute bacterial meningitis (ABM) and its early prognostication would guide the degree of intensive treatment required. We aimed to study the clinical features and factors associated with death in patients with community acquired ABM. METHODS:Adult patients with clinically suspected community acquired ABM (CAABM) were studied between July 2004 to September 2008 (retrospective and prospective). Detailed history, clinical examination, cerebrospinal fluid (CSF) analysis, and laboratory investigations were performed and noted. The complications with which the patient presented or developed during hospital course were also noted. The outcome noted was at the time of discharge. RESULTS:In multivariate logistic regression, independent factors associated with death were rural area of residence, presentation after >24 h, total leukocyte count (TLC) of <15000, CSF neutrophils <75%, low GCS at the time of admission, and a high creatinine level. CONCLUSIONS:In the present study, most of the factors predicting death were identified at the time of admission. Identification of these factors could help prioritizing patients needing intensive care facilities, especially in resource poor setting.
journal_name
Neurocrit Carejournal_title
Neurocritical careauthors
Vibha D,Bhatia R,Prasad K,Srivastava MV,Tripathi M,Singh MBdoi
10.1007/s12028-010-9396-4subject
Has Abstractpub_date
2010-10-01 00:00:00pages
199-204issue
2eissn
1541-6933issn
1556-0961journal_volume
13pub_type
杂志文章abstract：BACKGROUND:It is controversial whether a low cerebral blood flow (CBF) simply reflects the severity of injury or whether ischemia contributes to the brain's injury. It is also not clear whether posttraumatic cerebral hypoperfusion results from intracranial hypertension or from pathologic changes of the cerebral vascula...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1385/NCC:1:1:69
更新日期：2004-01-01 00:00:00
abstract：BACKGROUND:Cerebral blood flow (CBF) measurements are helpful in managing patients with traumatic brain injury (TBI), and testing the cerebrovascular reactivity to CO(2) provides information about injury severity and outcome. The complexity and potential hazard of performing CBF measurements limits routine clinical use...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-012-9727-8
更新日期：2014-02-01 00:00:00
abstract：BACKGROUND:Median nerve short-latency somatosensory evoked potentials (SSEPs) are useful in determining prognosis for awakening after coma following hypoxic ischemic encephalopathy, but reliability of interpretation is unclear. OBJECTIVE:To measure inter- and intra-observer reliability of determining presence or absen...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-009-9251-7
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:The aim of this study is to determine the utility of non-invasive bedside neuromonitoring, including cerebral regional oxygen saturation (rSO2) measured by near-infrared spectroscopy and serum biomarkers, in identifying children at risk from adverse neurological outcome after heart surgery. METHODS:Prospect...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-013-9934-y
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND/OBJECTIVE:Infection is the most common complication of external ventricular drain (EVD) placement. National trends in the annual incidence of meningitis among patients with traumatic brain injury (TBI) who have undergone EVD placement have not been reported. METHODS:The Nationwide Inpatient Sample was used ...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-018-0656-z
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Acute hydrocephalus is a common complication of aneurysmal subarachnoid hemorrhage (aSAH); however, attempts to predict shunt-dependent chronic hydrocephalus using clinical parameters have been equivocal. METHODS:Cohort study of aSAH is treated with external ventricular drainage (EVD) placement at our insti...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-019-00886-2
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:The natural history of cerebral aneurysms derived from metastatic spread of cardiac myxomas is not well known, and their management presents many dilemmas. METHODS:Case report and literature review. RESULTS:An 18-year-old man presented with an intraparenchymal hemorrhage several months after resection of a...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-010-9400-z
更新日期：2010-10-01 00:00:00
abstract：INTRODUCTION:Bacterial meningitis is associated with a high mortality and a high incidence of neurological sequelae. Parainfectious vasculitis leading to ischemic brain damage is a known complication of bacterial meningitis but its treatment is uncertain. METHODS AND RESULTS:We report the case of a 53-year-old man wit...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1385/NCC:4:3:237
更新日期：2006-01-01 00:00:00
abstract：INTRODUCTION:The incidence of spinal epidural abscesses (SEAs) is rising. Although increased awareness has led to decreased mortality, morbidity remains unacceptably high, with rapid deterioration of neurological status when there is a delay in initiation of treatment. Therefore, we need to build a better understanding...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1385/NCC:2:3:245
更新日期：2005-01-01 00:00:00
abstract：BACKGROUND:Although hydrocephalus is often treated with permanent cerebrospinal fluid (CSF) shunting during hospitalization for acute aneurysmal subarachnoid hemorrhage (SAH), little is known about the development of delayed hydrocephalus. METHODS:Using administrative data on all visits to nonfederal emergency departm...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-014-0072-y
更新日期：2015-08-01 00:00:00
abstract：INTRODUCTION:Altered mental status and more subtle cognitive and personality changes after traumatic brain injury (TBI) are pervasive problems in patients who survive initial injury. MRI is not necessarily part of the diagnostic evaluation of these patients. METHODS:Case report with relevant image and review of the li...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-012-9699-8
更新日期：2012-06-01 00:00:00
abstract：:A common observation in closed head injuries is the contrecoup brain injury. As the in vivo brain is less dense than the cerebrospinal fluid (CSF), one hypothesis explaining this observation is that upon skull impact, the denser CSF moves toward the site of skull impact displacing the brain in the opposite direction, ...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1385/NCC:1:3:385
更新日期：2004-01-01 00:00:00
abstract：INTRODUCTION:Methylene blue (MB) infusion is frequently used to localize the parathyroid glands during parathyroidectomy and generally considered safe. Several recent reports suggest neurological toxicity and post-operative altered mental state typically after large dose infusions. The mechanism by which MB has neuroto...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-009-9206-z
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:In comatose post-cardiac arrest patients, a serum neuron-specific enolase (NSE) level of >33 μg/L within 72 h was identified as a reliable marker for poor outcome in a large Dutch study (PROPAC), and this level was subsequently adopted in an American Academy of Neurology practice parameter. Later studies rep...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-013-9867-5
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:This study investigated if cerebral blood flow (CBF) regulation by changes of the arterial partial pressure of carbon dioxide (PaCO2) can be used therapeutically to increase CBF and improve neurological outcome after subarachnoid hemorrhage (SAH). METHODS:In 12 mechanically ventilated poor-grade SAH-patient...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-016-0246-x
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:In patients with spontaneous intracerebral hemorrhage (ICH), pre-hospital markers of disease severity might be useful to potentially triage patients to undergo early interventions. OBJECTIVE:Here, we tested whether loss of consciousness (LOC) at the onset of ICH is associated with intraventricular hemorrhag...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-020-01180-2
更新日期：2021-01-21 00:00:00
abstract：BACKGROUND:Neurogenic pulmonary edema (NPE) is an acute life-threatening complication associated with many forms of central nervous system injury. NPE usually appears within minutes to hours after injury and has a high mortality rate if not recognized and treated appropriately. Lung ultrasound quickly provides at the b...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-013-9828-z
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Intrahospital transport is associated with a high rate of complications. Investigations of this problem using neuromonitoring remain scarce. METHODS:This is a monocentric, prospective observational study. Patients with severe brain diseases and intracranial pressure (ICP) monitoring were included. Continuou...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-016-0274-6
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Plateau waves are common in traumatic brain injury. They constitute abrupt increases of intracranial pressure (ICP) above 40 mmHg associated with a decrease in cerebral perfusion pressure (CPP). The aim of this study was to describe plateau waves characteristics with multimodal brain monitoring in head injur...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-013-9918-y
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:Stroke due to occlusion of the artery of Percheron (AOP), an uncommon anatomic variant supplying the bilateral medial thalami, may raise diagnostic challenges and cause life-threatening symptoms. Our objective here was to detail the features and outcomes in three patients who required intensive care unit (ICU...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-014-9962-2
更新日期：2014-06-01 00:00:00
abstract：INTRODUCTION:The apnea test is a crucial component of the clinical diagnosis of brain death. Apprehension about hypoxemia, hypotension, and/or cardiac arrhythmias may sometimes lead clinicians to avoid performing or prematurely terminate the apnea test. The purpose of this study was to perform a contemporary re-evaluat...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-014-9958-y
更新日期：2014-12-01 00:00:00
abstract：INTRODUCTION:Spinal cord ischemia and stroke are recognized complications of descending thoracic (DTA) and thoracoabdominal aortic (TAA) operations. However, there are limited data available on outcomes since the advent of thoracic endovascular aortic repair (TEVAR). METHODS:We reviewed charts from consecutive patient...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-008-9104-9
更新日期：2008-01-01 00:00:00
abstract：:The presence of pulmonary dysfunction after brain injury is well recognized. Acute lung injury (ALI) occurs in 20% of patients with isolated brain injury and is associated with a poor outcome. The "blast injury" theory, which proposes combined "hydrostatic" and "high permeability" mechanisms for the formation of neuro...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-009-9242-8
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:To describe a case of auto-immune encephalitis in an adolescent with favorable outcome despite prolonged status epilepticus. METHODS:A 17 year old Asian man without previous medical history developed alteration of consciousness and partial seizures. The diagnosis of anti-N-methyl-D-aspartate receptor enceph...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-012-9788-8
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:Fever is associated with worse outcome after intracerebral hemorrhage (ICH). Autonomic dysfunction, commonly seen after brain injury, results in reduced heart rate variability (HRV). We sought to investigate whether HRV was associated with the development of fever in patients with ICH. METHODS:We prospectiv...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-019-00684-w
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Status, refractory status and super refractory status epilepticus are common neurologic emergencies. The objective of this study is to investigate the feasibility, safety and effectiveness of a ketogenic diet (KD) for refractory status epilepticus (RSE) in adults in the intensive care unit (ICU). METHODS:We...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-018-0653-2
更新日期：2019-06-01 00:00:00
abstract：INTRODUCTION:Dynamic testing of cerebral pressure autoregulation is more practical than static testing for critically ill patients. The process of cuff deflation is innocuous in the normal subject, but the systemic and cerebral effects of cuff deflation in severely head-injured patients have not been studied. The purpo...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1385/NCC:4:2:127
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Infection is common following stroke and is independently associated with worse outcome. Clinical studies suggest that infections occur more frequently in those individuals with stroke-induced immunologic dysfunction. This study sought to explore the contribution of immunomodulatory cytokines and hormones to...
journal_title：Neurocritical care
pub_type： 杂志文章
doi：10.1007/s12028-010-9490-7
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:Ischemic stroke and intracranial hemorrhage (ICH) following left ventricular assist device (LVAD) placement are major causes of morbidity. The incidence and mortality associated with these events stratified by device type have not been systematically explored. METHODS:A systematic review of PubMed was condu...
journal_title：Neurocritical care
pub_type： 杂志文章,评审
doi：10.1007/s12028-017-0386-7
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Apnea testing is an essential step in the clinical diagnosis of brain death. Current international guidelines recommend placement of an oxygen (O2) insufflation catheter into the endotracheal tube to prevent hypoxemia, but use of a continuous positive airway pressure (CPAP) valve may be more effective at lim...
journal_title：Neurocritical care
pub_type： 杂志文章,多中心研究
doi：10.1007/s12028-017-0380-0
更新日期：2017-08-01 00:00:00
