A controlled study of caudal epidural injections of triamcinolone plus procaine for the management of intractable sciatica.

Abstract:

:The management of sciatica due to lumbar nerve root compromise remains controversial, probably because few well-controlled studies of conservative management have been performed. This preliminary study assesses the efficacy of epidural injections of 80 mg triamcinolone acetonide plus 0.5% procaine hydrochloride in saline, administered via the caudal route, in a double-blind, placebo controlled trial with 1 year follow-up. Twenty-three patients were entered into the study: 12 received treatment and 11 placebo. The active group showed significant pain relief (P = 0.02) and a significant increase in mobility (P = 0.01) at 4 weeks, which resulted in improved quality of life (P = 0.02). At 1 year, subjective and objective measures improved in both groups. The improvement was greater in the actively treated group, but only the objective assessment (straight leg raise) was statistically significant.

journal_name

Spine (Phila Pa 1976)

journal_title

Spine

authors

Bush K,Hillier S

doi

10.1097/00007632-199105000-00015

subject

Has Abstract

pub_date

1991-05-01 00:00:00

pages

572-5

issue

5

eissn

0362-2436

issn

1528-1159

journal_volume

16

pub_type

临床试验,杂志文章,随机对照试验

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