当前位置： SCI文献检索 > HEART RHYTHM期刊下所有文献 > Molecular mechanisms of adrenergic stimulation in the heart.

Molecular mechanisms of adrenergic stimulation in the heart.

Abstract：

:Increased cardiac output in response to beta-adrenergic receptor stimulation is achieved by rapid alteration of the activity of cardiac ion channels, pumps, and exchangers. Over the past decade, the discovery of macromolecular complexes, which include the ion channels and pumps and the kinases that control their level of phosphorylation, has led to an increased understanding of the molecular mechanisms behind the cardiac adrenergic response. The increased understanding has led to the discovery of a new long QT gene encoding an accessory protein in one of these macromolecular complexes. This article briefly reviews the major components of the beta-adrenergic pathway in the heart and discusses the direction of current and future research.

journal_name

Heart Rhythm

journal_title

Heart rhythm

authors

Sampson KJ,Kass RS

doi

10.1016/j.hrthm.2010.02.013

subject

Has Abstract

pub_date

2010-08-01 00:00:00

pages

1151-3

issue

8

eissn

1547-5271

issn

1556-3871

pii

S1547-5271(10)00118-9

journal_volume

7

pub_type

杂志文章,评审

相关文献

HEART RHYTHM文献大全
  • Ciprofloxacin-induced acquired long QT syndrome.

    abstract：:Quinolone antibiotics have potentially serious proarrhythmic effects. The effects on intracardiac potassium channels result in QT interval prolongation, leading to torsades de pointes. Evidence suggests fluoroquinolones cause QT-mediated proarrhythmia, and weak evidence links ciprofloxacin with QT-mediated arrhythmias...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2004.06.020

    authors： Prabhakar M,Krahn AD

    更新日期：2004-11-01 00:00:00

  • Transvenous extraction of implantable cardioverter-defibrillator leads under advisory--a comparison of Riata, Sprint Fidelis, and non-recalled implantable cardioverter-defibrillator leads.

    abstract：BACKGROUND:Comparative safety and efficacy associated with transvenous lead extraction (TLE) of recalled and non-recalled implantable cardioverter-defibrillator (ICD) leads has not been well characterized. OBJECTIVES:To compare the indications, techniques, and procedural outcomes of recalled vs non-recalled ICD lead e...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2013.06.021

    authors： Brunner MP,Cronin EM,Jacob J,Duarte VE,Tarakji KG,Martin DO,Callahan T,Borek PP,Cantillon DJ,Niebauer MJ,Saliba WI,Kanj M,Wazni O,Baranowski B,Wilkoff BL

    更新日期：2013-10-01 00:00:00

  • Left atrial appendage closure device implantation in patients at very high risk for stroke.

    abstract：BACKGROUND:Little is known about the role of left atrial appendage closure using the Watchman device (Boston Scientific) in patients who are at very high risk for stroke. OBJECTIVE:The purpose of this study was to assess the role of Watchman in patients with CHA2DS2-VASc ≥5. METHODS:All patients undergoing procedures...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.07.011

    authors： Hutt E,Wazni OM,Kaur S,Saliba WI,Tarakji KG,Kapadia S,Aguilera J,Barakat AF,Abdallah M,Jaber W,Rasmussen P,Hussain S,Uchino K,Wisco D,Lindsay BD,Kanj M,Hussein AA

    更新日期：2020-01-01 00:00:00

  • Catheter ablation using the third-generation cryoballoon provides an enhanced ability to assess time to pulmonary vein isolation facilitating the ablation strategy: Short- and long-term results of a multicenter study.

    abstract：BACKGROUND:Limited data exist on cryoablation of atrial fibrillation (Cryo-AF) using the newly available third-generation (Arctic Front Advance-Short Tip [AFA-ST]) cryoballoon. OBJECTIVE:In this multicenter study, we evaluated the safety and efficacy of Cryo-AF using the AFA-ST vs the second-generation (Arctic Front A...

    journal_title：Heart rhythm

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.hrthm.2016.08.011

    authors： Aryana A,Kowalski M,O'Neill PG,Koo CH,Lim HW,Khan A,Hokanson RB,Bowers MR,Kenigsberg DN,Ellenbogen KA,Cryo-DOSING Investigators.

    更新日期：2016-12-01 00:00:00

  • Mortality after cardioverter-defibrillator replacement: Results of the DECODE survival score index.

    abstract：BACKGROUND:Device replacement is the ideal time to reassess health care goals regarding continuing implantable cardioverter-defibrillator (ICD) therapy. Only few data are available on the decision making at this time. OBJECTIVES:The goals of this study were to identify factors associated with poor prognosis at the tim...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2020.11.024

    authors： Zoni-Berisso M,Martignani C,Ammendola E,Narducci ML,Caruso D,Miracapillo G,Notarstefano P,Carinci V,Pierantozzi A,Ciaramitaro G,Calò L,Zennaro M,Infusino T,Ferretti C,Sassone B,Licciardello G,Setti S,Terzaghi C,Malacr

    更新日期：2020-11-27 00:00:00

  • Antitachycardia pacing for reduction of implantable cardioverter-defibrillator shocks.

    abstract：:Antitachycardia pacing (ATP) strategies represent safe, effective, and painless therapy for ventricular tachyarrhythmias, with a large body of clinical evidence supporting their routine use in both primary and secondary implantable cardioverter-defibrillator recipients. This article details the evidence supporting the...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2015.02.024

    authors： Cantillon DJ,Wilkoff BL

    更新日期：2015-06-01 00:00:00

  • Temporal trends and sex differences in pulmonary vein isolation for patients with atrial fibrillation.

    abstract：BACKGROUND:Indications for pulmonary vein isolation for the treatment of atrial fibrillation (AF) have expanded over the years. OBJECTIVE:We aimed to describe trends in demographic and clinical characteristics of patients undergoing ablation, with a particular focus on sex differences. METHODS:Patients who underwent ...

    journal_title：Heart rhythm

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.hrthm.2015.06.029

    authors： Avgil Tsadok M,Gagnon J,Joza J,Behlouli H,Verma A,Essebag V,Pilote L

    更新日期：2015-09-01 00:00:00

  • Incidence and predictors of atrial fibrillation progression: A systematic review and meta-analysis.

    abstract：BACKGROUND:More sustained forms of atrial fibrillation (AF) are less amenable to treatment and associated with worse outcomes, but the incidence and predictors of AF progression are not well defined. OBJECTIVE:The purpose of this study was to perform a systematic review and meta-analysis assessing the incidence and pr...

    journal_title：Heart rhythm

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.hrthm.2018.10.022

    authors： Blum S,Meyre P,Aeschbacher S,Berger S,Auberson C,Briel M,Osswald S,Conen D

    更新日期：2019-04-01 00:00:00

  • Inside-out access: a new method of lead placement for patients with central venous occlusions.

    abstract：BACKGROUND:Physicians will increasingly encounter patients who require rhythm management devices but have venous obstructions that prevent conventional access. Alternate access options, such as thoracotomy or transiliac approaches, exist but are associated with greater cost and morbidity. OBJECTIVE:The purpose of this...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2011.01.024

    authors： Elayi CS,Allen CL,Leung S,Lusher S,Morales GX,Wiisanen M,Aikat S,Kakavand B,Shah JS,Moliterno DJ,Gurley JC

    更新日期：2011-06-01 00:00:00

  • A clinical feasibility study of atrial and ventricular electromechanical wave imaging.

    abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) and atrial ablation procedures currently lack a noninvasive imaging modality for reliable treatment planning and monitoring. Electromechanical wave imaging (EWI) is an ultrasound-based method that has previously been shown to be capable of noninvasively and transmurall...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2013.02.028

    authors： Provost J,Gambhir A,Vest J,Garan H,Konofagou EE

    更新日期：2013-06-01 00:00:00

  • Long QT syndrome type 5-Lite: Defining the clinical phenotype associated with the potentially proarrhythmic p.Asp85Asn-KCNE1 common genetic variant.

    abstract：BACKGROUND:Long QT syndrome (LQTS) genetic test reports commonly exclude potentially proarrhythmic common variants such as p.Asp85Asn-KCNE1. OBJECTIVE:The purpose of this study was to determine whether a discernible phenotype is associated with p.Asp85Asn-KCNE1 and whether relatively common KCNE1 variants underlie tra...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2018.03.038

    authors： Lane CM,Giudicessi JR,Ye D,Tester DJ,Rohatgi RK,Bos JM,Ackerman MJ

    更新日期：2018-08-01 00:00:00

  • Population-based analysis of sudden death in children: The Oregon Sudden Unexpected Death Study.

    abstract：BACKGROUND:There is a lack of prospective population-based data regarding sudden death in children. OBJECTIVE:The purpose of this study was to assess the burden of sudden cardiac arrest (SCA) in the pediatric population in a 3-year community-wide study. METHODS:During 2002-2005, all residents of Multnomah County, Ore...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2009.07.046

    authors： Chugh SS,Reinier K,Balaji S,Uy-Evanado A,Vickers C,Mariani R,Gunson K,Jui J

    更新日期：2009-11-01 00:00:00

  • Catheter ablation of polymorphic ventricular tachycardia/fibrillation in patients with and without structural heart disease.

    abstract：BACKGROUND:Catheter ablation for polymorphic ventricular tachycardia and ventricular fibrillation (PMVT/VF) may target triggering premature ventricular contractions (PVCs). Targeting ventricular scar has also been suggested, but data are limited. OBJECTIVE:The purpose of this study was to characterize the electrophysi...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.01.032

    authors： Nakamura T,Schaeffer B,Tanigawa S,Muthalaly RG,John RM,Michaud GF,Tedrow UB,Stevenson WG

    更新日期：2019-07-01 00:00:00

  • Heart failure enhances susceptibility to arrhythmogenic cardiac alternans.

    abstract：BACKGROUND:Although heart failure (HF) is closely associated with susceptibility to sudden cardiac death (SCD), the mechanisms linking contractile dysfunction to cardiac electrical instability are poorly understood. Cardiac alternans has also been closely associated with SCD, and has been linked to a mechanism for ampl...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2008.11.008

    authors： Wilson LD,Jeyaraj D,Wan X,Hoeker GS,Said TH,Gittinger M,Laurita KR,Rosenbaum DS

    更新日期：2009-02-01 00:00:00

  • Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study.

    abstract：BACKGROUND:Genome-wide association studies (GWAS) have identified common genetic variants that predispose to atrial fibrillation (AF). It is unclear whether rare and low-frequency variants in genes implicated by such GWAS confer additional risk of AF. OBJECTIVE:To study the association of genetic variants with AF at G...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2013.11.012

    authors： Lin H,Sinner MF,Brody JA,Arking DE,Lunetta KL,Rienstra M,Lubitz SA,Magnani JW,Sotoodehnia N,McKnight B,McManus DD,Boerwinkle E,Psaty BM,Rotter JI,Bis JC,Gibbs RA,Muzny D,Kovar CL,Morrison AC,Gupta M,Folsom AR,Kä

    更新日期：2014-03-01 00:00:00

  • Automated intraprocedural localization of origin of ventricular activation using patient-specific computed tomographic imaging.

    abstract：BACKGROUND:To facilitate catheter ablation of ventricular tachycardia (VT), we previously developed an automated method to identify sources of left ventricular (LV) activation in real time using 12-lead electrocardiography (ECG), the accuracy of which depends on acquisition of a complete electroanatomic (EA) map. OBJE...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.10.025

    authors： Zhou S,Sapp JL,Horáček BM,Warren JW,MacInnis PJ,Davis J,Elsokkari I,Choudhury R,Parkash R,Gray C,Gardner M,MacIntyre CJ,AbdelWahab A

    更新日期：2020-04-01 00:00:00

  • Adaptive cardiac resynchronization therapy is associated with decreased risk of incident atrial fibrillation compared to standard biventricular pacing: A real-world analysis of 37,450 patients followed by remote monitoring.

    abstract：BACKGROUND:The AdaptivCRT algorithm (aCRT) automatically adjusts atrioventricular delays each minute to achieve ventricular fusion through left ventricular (LV) or biventricular (BiV) pacing. aCRT is associated with superior clinical outcomes compared to standard BiV pacing, but the association of aCRT and subsequent a...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.05.012

    authors： Hsu JC,Birnie D,Stadler RW,Cerkvenik J,Feld GK,Birgersdotter-Green U

    更新日期：2019-07-01 00:00:00

  • Clinical presentation of ventricular-Hisian and ventricular-nodal accessory pathways.

    abstract：BACKGROUND:Narrow QRS tachycardia or premature beat with bystander atrial activation or ventricular-atrial dissociation is an unusual arrhythmia that can present diagnostic and therapeutic challenges. When ventricular-atrial conduction is robust, these arrhythmias can be difficult to distinguish from atrioventricular n...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2018.08.006

    authors： Chung R,Wazni O,Dresing T,Chung M,Saliba W,Lindsay B,Tchou P

    更新日期：2019-03-01 00:00:00

  • Cardiac magnetic resonance imaging using wideband sequences in patients with nonconditional cardiac implanted electronic devices.

    abstract：BACKGROUND:Magnetic resonance imaging (MRI) has been performed safely in patients without MRI-conditional cardiac implantable electronic devices (CIEDs), but experience specifically with cardiac magnetic resonance imaging (CMR) is limited in this patient population. OBJECTIVE:Evaluate the safety of CMR in non-MRI-cond...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2017.10.003

    authors： Do DH,Eyvazian V,Bayoneta AJ,Hu P,Finn JP,Bradfield JS,Shivkumar K,Boyle NG

    更新日期：2018-02-01 00:00:00

  • Incidence of sudden cardiac arrest in high school student athletes on school campus.

    abstract：BACKGROUND:An accurate estimate of the incidence of sudden cardiac arrest (SCA) in high school student athletes is needed to guide prevention strategies. OBJECTIVE:To prospectively investigate SCA rates in high school student athletes vs student nonathletes. METHODS:A prospective observational study of 2149 US high s...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2014.04.017

    authors： Toresdahl BG,Rao AL,Harmon KG,Drezner JA

    更新日期：2014-07-01 00:00:00

  • Outcomes of patients admitted with ventricular arrhythmias and sudden cardiac death in the United States.

    abstract：BACKGROUND:Mortality caused by ventricular arrhythmias (VAs) remains a problem of epidemic proportions. Understanding current trends on admission of VA, patient characteristics, morbidity, mortality, and health care utilization could help us improve allocation of health care resources and risk prediction. OBJECTIVE:Th...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2018.09.007

    authors： Viles-Gonzalez JF,Arora S,Deshmukh A,Atti V,Agnihotri K,Patel N,Dave M,Anter E,Garcia F,Santangeli P,Goldberger JJ,Dukkipati S,d'Avila A,Natale A,Di Biase L

    更新日期：2019-03-01 00:00:00

  • High-frequency powers hidden within QRS complex as an additional predictor of lethal ventricular arrhythmias to ventricular late potential in post-myocardial infarction patients.

    abstract：BACKGROUND:Ventricular late potentials (VLPs) have been known to be a predictor of lethal ventricular arrhythmias (L-VAs); however, detection of other arrhythmogenic signals within the QRS complex remains obscure. OBJECTIVE:The aim of this study was to evaluate whether abnormal intra-QRS high-frequency powers (IQHFP) ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2011.06.027

    authors： Tsutsumi T,Takano N,Matsuyama N,Higashi Y,Iwasawa K,Nakajima T

    更新日期：2011-10-01 00:00:00

  • Cardiac electrophysiology of patients with spinal cord injury.

    abstract：:Spinal cord injury is a clinical syndrome encountered frequently in trauma centers and is accompanied by both acute and chronic heart rhythm abnormalities. The injury is characterized by sympathetic nervous system impairment with preservation of parasympathetic output via the vagus nerve. Severe bradycardia in the for...

    journal_title：Heart rhythm

    pub_type： 杂志文章,评审

    doi：10.1016/j.hrthm.2017.02.015

    authors： Manogue M,Hirsh DS,Lloyd M

    更新日期：2017-06-01 00:00:00

  • Risk of atrial fibrillation as a function of the electrocardiographic PR interval: results from the Copenhagen ECG Study.

    abstract：BACKGROUND:Prolongation of the PR interval has been associated with an increased risk of incident atrial fibrillation (AF). OBJECTIVE:To determine if there was a nonlinear relation between PR interval duration and the risk of AF. METHODS:We included 288,181 individuals, corresponding to one third of the population in...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2013.04.012

    authors： Nielsen JB,Pietersen A,Graff C,Lind B,Struijk JJ,Olesen MS,Haunsø S,Gerds TA,Ellinor PT,Køber L,Svendsen JH,Holst AG

    更新日期：2013-09-01 00:00:00

  • Incidence and causes of in-hospital outcomes and 30-day readmissions after percutaneous left atrial appendage closure: A US nationwide retrospective cohort study using claims data.

    abstract：BACKGROUND:Percutaneous left atrial appendage closure (pLAAC) emerged as an option for stroke prevention in patients with atrial fibrillation ineligible for long-term anticoagulation. Real-world data on pLAAC's in-hospital and 30-day readmission measures are limited. OBJECTIVE:We sought to report the nationwide incide...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2019.09.018

    authors： Vuddanda VLK,Turagam MK,Umale NA,Shah Z,Lakkireddy DR,Bartus K,McCausland FR,Velagapudi P,Mansour M,Heist EK

    更新日期：2020-03-01 00:00:00

  • Differential diagnosis of regular, narrow-QRS tachycardias.

    abstract：:We present an update on clinical and electrophysiological criteria used for the differential diagnosis of regular supraventricular tachycardias. Although several electrocardiographic clues may assist in the differential diagnosis, this is usually accomplished at electrophysiology study, and most often, the differentia...

    journal_title：Heart rhythm

    pub_type： 杂志文章,评审

    doi：10.1016/j.hrthm.2015.03.046

    authors： Katritsis DG,Josephson ME

    更新日期：2015-07-01 00:00:00

  • Does the number of simultaneously activated electrodes during phased RF multielectrode ablation of atrial fibrillation influence the incidence of silent cerebral microembolism?

    abstract：BACKGROUND:Asymptomatic cerebral embolus (ACE) detected by diffusion-weighted magnetic resonance imaging (DW-MRI) following atrial fibrillation (AF) ablation has been reported at varying rates with different ablation techniques. OBJECTIVE:To evaluate the incidence of ACE after phased radiofrequency ablation for AF wit...

    journal_title：Heart rhythm

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.hrthm.2013.04.005

    authors： Wieczorek M,Hoeltgen R,Brueck M

    更新日期：2013-07-01 00:00:00

  • Adenosine testing during cryoballoon ablation and radiofrequency ablation of atrial fibrillation: A propensity score-matched analysis.

    abstract：BACKGROUND:The infusion of adenosine triphosphate after radiofrequency (RF) pulmonary vein (PV) isolation (PVI), which may result in acute transient PV-atrium reconnection, can unmask dormant conduction. OBJECTIVE:The purpose of this study was to compare the incidence and characteristics of dormant conduction after cr...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2016.08.018

    authors： Tokuda M,Matsuo S,Isogai R,Uno G,Tokutake K,Yokoyama K,Kato M,Narui R,Tanigawa S,Yamashita S,Inada K,Yoshimura M,Yamane T

    更新日期：2016-11-01 00:00:00

  • Outcomes of nonpharmacologic treatment of atrial fibrillation in patients with hypertrophic cardiomyopathy.

    abstract：BACKGROUND:Limited data exist regarding the outcome of atrial fibrillation (AF) surgery and catheter ablation in patients with hypertrophic cardiomyopathy (HCM). OBJECTIVE:The purpose of this study was to evaluate the safety and efficacy of nonpharmacologic treatment of AF in HCM. METHODS:One hundred forty-seven pati...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2015.03.042

    authors： Bassiouny M,Lindsay BD,Lever H,Saliba W,Klein A,Banna M,Abraham J,Shao M,Rickard J,Kanj M,Tchou P,Dresing T,Baranowski B,Bhargava M,Callahan T,Tarakji K,Cantillon D,Hussein A,Marc Gillinov A,Smedira NG,Wazni O

    更新日期：2015-07-01 00:00:00

  • Pathophysiologic basis of autonomic ganglionated plexus ablation in patients with atrial fibrillation.

    abstract：:The intrinsic cardiac autonomic nervous system (ganglionated plexuses [GP]) plays a significant role in the initiation and maintenance of atrial fibrillation (AF) in both experimental models and AF patients. Left atrial GP, located in epicardial fat pads and the ligament of Marshall, contain afferent neurons from the ...

    journal_title：Heart rhythm

    pub_type： 杂志文章

    doi：10.1016/j.hrthm.2009.07.029

    authors： Nakagawa H,Scherlag BJ,Patterson E,Ikeda A,Lockwood D,Jackman WM

    更新日期：2009-12-01 00:00:00