Tonotopic organization of human auditory cortex.

Abstract:

:The organization of tonotopic fields in human auditory cortex was investigated using functional magnetic resonance imaging. Subjects were presented with stochastically alternating multi-tone sequences in six different frequency bands, centered at 200, 400, 800, 1600, 3200, and 6400 Hz. Two mirror-symmetric frequency gradients were found extending along an anterior-posterior axis from a zone on the lateral aspect of Heschl's gyrus (HG), which responds preferentially to lower frequencies, toward zones posterior and anterior to HG that are sensitive to higher frequencies. The orientation of these two principal gradients is thus roughly perpendicular to HG, rather than parallel as previously assumed. A third, smaller gradient was observed in the lateral posterior aspect of the superior temporal gyrus. The results suggest close homologies between the tonotopic organization of human and nonhuman primate auditory cortex.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Humphries C,Liebenthal E,Binder JR

doi

10.1016/j.neuroimage.2010.01.046

subject

Has Abstract

pub_date

2010-04-15 00:00:00

pages

1202-11

issue

3

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(10)00068-6

journal_volume

50

pub_type

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