当前位置： SCI文献检索 > NEUROIMAGE期刊下所有文献 > Patient classification as an outlier detection problem: an application of the One-Class Support Vector Machine.

Patient classification as an outlier detection problem: an application of the One-Class Support Vector Machine.

Abstract：

:Pattern recognition approaches, such as the Support Vector Machine (SVM), have been successfully used to classify groups of individuals based on their patterns of brain activity or structure. However these approaches focus on finding group differences and are not applicable to situations where one is interested in accessing deviations from a specific class or population. In the present work we propose an application of the one-class SVM (OC-SVM) to investigate if patterns of fMRI response to sad facial expressions in depressed patients would be classified as outliers in relation to patterns of healthy control subjects. We defined features based on whole brain voxels and anatomical regions. In both cases we found a significant correlation between the OC-SVM predictions and the patients' Hamilton Rating Scale for Depression (HRSD), i.e. the more depressed the patients were the more of an outlier they were. In addition the OC-SVM split the patient groups into two subgroups whose membership was associated with future response to treatment. When applied to region-based features the OC-SVM classified 52% of patients as outliers. However among the patients classified as outliers 70% did not respond to treatment and among those classified as non-outliers 89% responded to treatment. In addition 89% of the healthy controls were classified as non-outliers.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Mourão-Miranda J,Hardoon DR,Hahn T,Marquand AF,Williams SC,Shawe-Taylor J,Brammer M

doi

10.1016/j.neuroimage.2011.06.042

subject

Has Abstract

pub_date

2011-10-01 00:00:00

pages

793-804

issue

3

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(11)00687-2

journal_volume

58

pub_type

杂志文章

相关文献

NEUROIMAGE文献大全
  • A Bayesian spatiotemporal model for very large data sets.

    abstract：:Functional MRI provides a unique perspective of neuronal organization; however, these data include many complex sources of spatiotemporal variability, which require spatial preprocessing and statistical analysis. For the latter, Bayesian models provide a promising alternative to classical inference, which uses results...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2009.12.042

    authors： Harrison LM,Green GG

    更新日期：2010-04-15 00:00:00

  • Accelerated cerebral white matter development in preterm infants: a voxel-based morphometry study with diffusion tensor MR imaging.

    abstract：:Twenty-seven preterm infants were compared to 10 full-term infants at term equivalent age using a voxel-based analysis of diffusion tensor imaging of the brain. Preterm infants exhibited higher fractional anisotropy values, which may suggest accelerated maturation, in the location of the sagittal stratum. While some e...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.02.029

    authors： Giménez M,Miranda MJ,Born AP,Nagy Z,Rostrup E,Jernigan TL

    更新日期：2008-07-01 00:00:00

  • Behavioral interventions for reducing head motion during MRI scans in children.

    abstract：:A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head motion artifacts. Even submillimeter movements can systematically distort functional connectivity, morphometric, and diffusion imaging results. In patient care, sedation is often used to minimize head motion, but it incurs...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.01.023

    authors： Greene DJ,Koller JM,Hampton JM,Wesevich V,Van AN,Nguyen AL,Hoyt CR,McIntyre L,Earl EA,Klein RL,Shimony JS,Petersen SE,Schlaggar BL,Fair DA,Dosenbach NUF

    更新日期：2018-05-01 00:00:00

  • Functional localization of the auditory thalamus in individual human subjects.

    abstract：:Here we describe an easily implemented protocol based on sparse MR acquisition and a scrambled 'music' auditory stimulus that allows for reliable measurement of functional activity within the medial geniculate body (MGB, the primary auditory thalamic nucleus) in individual subjects. We find that our method is equally ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2013.04.035

    authors： Jiang F,Stecker GC,Fine I

    更新日期：2013-09-01 00:00:00

  • Fast high resolution whole brain T2* weighted imaging using echo planar imaging at 7T.

    abstract：:Magnetic susceptibility based (T(2)* weighted) contrast in MRI at high magnetic field strength is of great value in research on brain structure and cortical architecture, but its use is hampered by the low signal-to-noise ratio (SNR) efficiency of the conventional spoiled gradient echo sequence (GRE) leading to long s...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.03.046

    authors： Zwanenburg JJ,Versluis MJ,Luijten PR,Petridou N

    更新日期：2011-06-15 00:00:00

  • DTI and MTR abnormalities in schizophrenia: analysis of white matter integrity.

    abstract：:Diffusion tensor imaging (DTI) studies in schizophrenia demonstrate lower anisotropic diffusion within white matter due either to loss of coherence of white matter fiber tracts, to changes in the number and/or density of interconnecting fiber tracts, or to changes in myelination, although methodology as well as locali...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2005.03.026

    authors： Kubicki M,Park H,Westin CF,Nestor PG,Mulkern RV,Maier SE,Niznikiewicz M,Connor EE,Levitt JJ,Frumin M,Kikinis R,Jolesz FA,McCarley RW,Shenton ME

    更新日期：2005-07-15 00:00:00

  • Cognitive versus automatic mechanisms of mood induction differentially activate left and right amygdala.

    abstract：:The amygdala plays a key role in emotional processing. The specific contribution of the amygdala during the experience of one's own emotion, however, remains controversial and requires clarification. There is a long-standing debate on hemispheric lateralization of emotional processes, yet few studies to date directly ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.10.013

    authors： Dyck M,Loughead J,Kellermann T,Boers F,Gur RC,Mathiak K

    更新日期：2011-02-01 00:00:00

  • Structural consequences of diffuse traumatic brain injury: a large deformation tensor-based morphometry study.

    abstract：:Traumatic brain injury (TBI) is one of the most common causes of long-term disability. Despite the importance of identifying neuropathology in individuals with chronic TBI, methodological challenges posed at the stage of inter-subject image registration have hampered previous voxel-based MRI studies from providing a c...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2007.10.005

    authors： Kim J,Avants B,Patel S,Whyte J,Coslett BH,Pluta J,Detre JA,Gee JC

    更新日期：2008-02-01 00:00:00

  • Is neuroenhancement by noninvasive brain stimulation a net zero-sum proposition?

    abstract：:In the past several years, the number of studies investigating enhancement of cognitive functions through noninvasive brain stimulation (NBS) has increased considerably. NBS techniques, such as transcranial magnetic stimulation and transcranial current stimulation, seem capable of enhancing cognitive functions in pati...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2013.07.038

    authors： Brem AK,Fried PJ,Horvath JC,Robertson EM,Pascual-Leone A

    更新日期：2014-01-15 00:00:00

  • Reproducibility of tract segmentation between sessions using an unsupervised modelling-based approach.

    abstract：:This work describes a reproducibility analysis of scalar water diffusion parameters, measured within white matter tracts segmented using a probabilistic shape modelling method. In common with previously reported neighbourhood tractography (NT) work, the technique optimises seed point placement for fibre tracking by ma...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.12.010

    authors： Clayden JD,Storkey AJ,Muñoz Maniega S,Bastin ME

    更新日期：2009-04-01 00:00:00

  • A pilot study of human brain tissue post-magnetic resonance imaging: information from the National Deep Brain Stimulation Brain Tissue Network (DBS-BTN).

    abstract：INTRODUCTION:The safety of magnetic resonance imaging (MRI) for deep brain stimulation (DBS) patients is of great importance to both movement disorders clinicians and to radiologists. The present study utilized the Deep Brain Stimulation Brain Tissue Network's (DBS-BTN's) clinical and neuropathological database to sear...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.09.014

    authors： Ullman M,Vedam-Mai V,Krock N,Sudhyadhom A,Foote KD,Yachnis AT,Merritt S,Resnick AS,Zeilman P,Okun MS

    更新日期：2011-01-01 00:00:00

  • The effect of practice on a sustained attention task in cocaine abusers.

    abstract：:Habituation enables the organism to attend selectively to novel stimuli by diminishing no-longer necessary responses to repeated stimuli. Because the prefrontal cortex (PFC) has a core role in monitoring attention and behavioral control especially under novelty, neural habituation responses may be modified in drug add...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2006.12.004

    authors： Goldstein RZ,Tomasi D,Alia-Klein N,Zhang L,Telang F,Volkow ND

    更新日期：2007-03-01 00:00:00

  • Advances in microstructural diffusion neuroimaging for psychiatric disorders.

    abstract：:Understanding the neuropathological underpinnings of mental disorders such as schizophrenia, major depression, and bipolar disorder is an essential step towards the development of targeted treatments. Diffusion MRI studies utilizing the diffusion tensor imaging (DTI) model have been extremely successful to date in ide...

    journal_title：NeuroImage

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroimage.2018.04.051

    authors： Pasternak O,Kelly S,Sydnor VJ,Shenton ME

    更新日期：2018-11-15 00:00:00

  • Frontostriatal system in planning complexity: a parametric functional magnetic resonance version of Tower of London task.

    abstract：:In the present study, we sought to investigate which brain structures are recruited in planning tasks of increasing complexity. For this purpose, a parametric self-paced pseudo-randomized event-related functional MRI version of the Tower of London task was designed. We tested 22 healthy subjects, enabling assessment o...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/s1053-8119(02)00010-1

    authors： van den Heuvel OA,Groenewegen HJ,Barkhof F,Lazeron RH,van Dyck R,Veltman DJ

    更新日期：2003-02-01 00:00:00

  • Language in context: emergent features of word, sentence, and narrative comprehension.

    abstract：:Context exerts a powerful effect on cognitive performance and is clearly important for language processing, where lexical, sentential, and narrative contexts should differentially engage neural systems that support lexical, compositional, and discourse level semantics. Equally important, but thus far unexplored, is th...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2004.12.013

    authors： Xu J,Kemeny S,Park G,Frattali C,Braun A

    更新日期：2005-04-15 00:00:00

  • Surface area and cortical thickness descriptors reveal different attributes of the structural human brain networks.

    abstract：:Recently, a related morphometry-based connection concept has been introduced using local mean cortical thickness and volume to study the underlying complex architecture of the brain networks. In this article, the surface area is employed as a morphometric descriptor to study the concurrent changes between brain struct...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.01.028

    authors： Sanabria-Diaz G,Melie-García L,Iturria-Medina Y,Alemán-Gómez Y,Hernández-González G,Valdés-Urrutia L,Galán L,Valdés-Sosa P

    更新日期：2010-05-01 00:00:00

  • Glucose metabolism of the midline nuclei raphe in the brainstem observed by PET-MRI fusion imaging.

    abstract：UNLABELLED:The brainstem contains various important monoaminergic neuronal centers, including the raphe nuclei which contain serotonergic neurons. The raphe nuclei, however, are not easily identifiable and located by conventional neuroimaging. METHODS:Fluorodeoxyglucose positron emission tomography (PET) and magnetic ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2011.09.036

    authors： Son YD,Cho ZH,Kim HK,Choi EJ,Lee SY,Chi JG,Park CW,Kim YB

    更新日期：2012-01-16 00:00:00

  • The posterior cingulate and medial prefrontal cortex mediate the anticipatory allocation of spatial attention.

    abstract：:The purpose of this study was to identify brain regions underlying internally generated anticipatory biases toward locations where significant events are expected to occur. Subjects fixated centrally and responded to peripheral targets preceded by a spatially valid (predictive), invalid (misleading), or neutral centra...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/s1053-8119(02)00012-5

    authors： Small DM,Gitelman DR,Gregory MD,Nobre AC,Parrish TB,Mesulam MM

    更新日期：2003-03-01 00:00:00

  • White matter alterations to cingulum and fornix following very preterm birth and their relationship with cognitive functions.

    abstract：:Very preterm birth (VPT; <32 weeks of gestation) has been associated with impairments in memory abilities and functional neuroanatomical brain alterations in medial temporal and fronto-parietal areas. Here we investigated the relationship between structural connectivity in memory-related tracts and various aspects of ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2017.02.026

    authors： Caldinelli C,Froudist-Walsh S,Karolis V,Tseng CE,Allin MP,Walshe M,Cuddy M,Murray RM,Nosarti C

    更新日期：2017-04-15 00:00:00

  • Quantitative examination of a novel clustering method using magnetic resonance diffusion tensor tractography.

    abstract：:MR diffusion tensor imaging (DTI) can measure and visualize organization of white matter fibre tracts in vivo. DTI is a relatively new imaging technique, and new tools developed for quantifying fibre tracts require evaluation. The purpose of this study was to compare the reliability of a novel clustering approach with...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.12.028

    authors： Voineskos AN,O'Donnell LJ,Lobaugh NJ,Markant D,Ameis SH,Niethammer M,Mulsant BH,Pollock BG,Kennedy JL,Westin CF,Shenton ME

    更新日期：2009-04-01 00:00:00

  • Functional hierarchy for tactile processing in the visual cortex of sighted adults.

    abstract：:Perception via different sensory modalities was traditionally believed to be supported by largely separate brain systems. However, a growing number of studies demonstrate that the visual cortices of typical, sighted adults are involved in tactile and auditory perceptual processing. Here, we investigated the spatiotemp...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116084

    authors： Bola Ł,Matuszewski J,Szczepanik M,Droździel D,Sliwinska MW,Paplińska M,Jednoróg K,Szwed M,Marchewka A

    更新日期：2019-11-15 00:00:00

  • Layer specific tracing of corticocortical and thalamocortical connectivity in the rodent using manganese enhanced MRI.

    abstract：:Information about layer specific connections in the brain comes mainly from classical neuronal tracers that rely on histology. Manganese Enhanced MRI (MEMRI) has mapped connectivity along a number of brain pathways in several animal models. It is not clear at what level of specificity neuronal connectivity measured us...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2008.07.036

    authors： Tucciarone J,Chuang KH,Dodd SJ,Silva A,Pelled G,Koretsky AP

    更新日期：2009-02-01 00:00:00

  • Characterizing the relationship between BOLD contrast and regional cerebral blood flow measurements by varying the stimulus presentation rate.

    abstract：:This paper investigates the relationship between the blood oxygenation level dependent (BOLD) contrast effect and regional cerebral blood flow using the techniques of functional MRI (fMRI) and positron emission tomography (PET). A passive listening paradigm with parametric variation in word presentation rate was used ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1006/nimg.1997.0300

    authors： Rees G,Howseman A,Josephs O,Frith CD,Friston KJ,Frackowiak RS,Turner R

    更新日期：1997-11-01 00:00:00

  • Perception of object motion in three-dimensional space induced by cast shadows.

    abstract：:Cast shadows can be salient depth cues in three-dimensional (3D) vision. Using a motion illusion in which a ball is perceived to roll in depth on the bottom or to flow in the front plane depending on the slope of the trajectory of its cast shadow, we investigated cortical mechanisms underlying 3D vision based on cast ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2010.07.075

    authors： Katsuyama N,Usui N,Nose I,Taira M

    更新日期：2011-01-01 00:00:00

  • Evidence for age-related changes in sensorimotor neuromagnetic responses during cued button pressing in a large open-access dataset.

    abstract：:Mu, beta, and gamma rhythms increase and decrease in amplitude during movement. This event-related synchronization (ERS) and desynchronization (ERD) can be readily recorded non-invasively using magneto- and electro-encephalography (M/EEG). In addition, event-related potentials and fields (i.e., evoked responses) can b...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.02.065

    authors： Bardouille T,Bailey L,CamCAN Group.

    更新日期：2019-06-01 00:00:00

  • Local temporal variability reflects functional integration in the human brain.

    abstract：:Local moment-to-moment variability exists at every level of neural organization, but its driving forces remain opaque. Inspired by animal work demonstrating that local temporal variability may reflect synaptic input rather than locally-generated "noise," we used publicly-available high-temporal-resolution fMRI data (N...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2018.08.019

    authors： Garrett DD,Epp SM,Perry A,Lindenberger U

    更新日期：2018-12-01 00:00:00

  • White matter information flow mapping from diffusion MRI and EEG.

    abstract：:The human brain can be described as a network of specialized and spatially distributed regions. The activity of individual regions can be estimated using electroencephalography and the structure of the network can be measured using diffusion magnetic resonance imaging. However, the communication between the different ...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2019.116017

    authors： Deslauriers-Gauthier S,Lina JM,Butler R,Whittingstall K,Gilbert G,Bernier PM,Deriche R,Descoteaux M

    更新日期：2019-11-01 00:00:00

  • Multi-resolutional shape features via non-Euclidean wavelets: applications to statistical analysis of cortical thickness.

    abstract：:Statistical analysis on arbitrary surface meshes such as the cortical surface is an important approach to understanding brain diseases such as Alzheimer's disease (AD). Surface analysis may be able to identify specific cortical patterns that relate to certain disease characteristics or exhibit differences between grou...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2014.02.028

    authors： Kim WH,Singh V,Chung MK,Hinrichs C,Pachauri D,Okonkwo OC,Johnson SC,Alzheimer's Disease Neuroimaging Initiative.

    更新日期：2014-06-01 00:00:00

  • Age-related trends in neuromagnetic transient beta burst characteristics during a sensorimotor task and rest in the Cam-CAN open-access dataset.

    abstract：:Non-invasive neurophysiological recordings, such as those measured by magnetoencelography (MEG), provide insight into the behaviour of neural networks and how these networks change with factors such as task performance, disease state, and age. Recently, there has been a trend in describing neurophysiological recording...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2020.117245

    authors： Brady B,Power L,Bardouille T

    更新日期：2020-11-15 00:00:00

  • Joint analysis of spikes and local field potentials using copula.

    abstract：:Recent technological advances, which allow for simultaneous recording of spikes and local field potentials (LFPs) at multiple sites in a given cortical area or across different areas, have greatly increased our understanding of signal processing in brain circuits. Joint analysis of simultaneously collected spike and L...

    journal_title：NeuroImage

    pub_type： 杂志文章

    doi：10.1016/j.neuroimage.2016.03.030

    authors： Hu M,Li M,Li W,Liang H

    更新日期：2016-06-01 00:00:00