Abstract:
:Ulcerative colitis is a chronic inflammatory disease of the colon with an increasing incidence worldwide. The medical management of this disease continues to expand as drugs to induce and maintain remission are sought to avoid the need for colectomy. This article will review the standard of care for the treatment of mild, moderate, and severe ulcerative colitis. The efficacy, optimal usage, and adverse events profile of agents such as 5-aminosalicylates, corticosteroids, azathioprine, and cyclosporine will be discussed and an algorithm for their use will be developed. Alternative and experimental therapies such as monoclonal antibodies, probiotics, and heparin will also be addressed.
journal_name
Clin Colon Rectal Surgjournal_title
Clinics in colon and rectal surgeryauthors
Mahadevan Udoi
10.1055/s-2004-823066subject
Has Abstractpub_date
2004-02-01 00:00:00pages
7-19issue
1eissn
1531-0043issn
1530-9681journal_volume
17pub_type
杂志文章abstract::When utilized properly, social media offers several personal and professional benefits for the practicing surgeon, including peer networking, education, e-mentorship, marketing, recruitment, and patient outreach. However, unprofessional online behavior is common among surgeons, and this improper use of social media ca...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1604255
更新日期:2017-09-01 00:00:00
abstract::Nodal dissemination in locally advanced rectal cancer occurs mainly in two directions: upward and lateral. Lateral node involvement has been demonstrated; however, lateral lymph node dissection (LLND) is not routinely performed in Western countries and the focus is more on neoadjuvant treatment regimens. The main reas...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1606112
更新日期:2017-11-01 00:00:00
abstract::Parasitic infections are a major worldwide health problem, and they account for millions of infections and deaths each year. Most of the infections as well as the morbidity and mortality from these diseases occur in the developing world in rural regions. However, these diseases have become more common in Western count...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-2007-970199
更新日期:2007-02-01 00:00:00
abstract::Advanced primary and recurrent colorectal cancer can be successfully treated by experienced, dedicated centers delivering good outcomes with low mortality and morbidity. Development and implementation of a comprehensive referral pathway is to be encouraged. Multidisciplinary team management is essential in the managem...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1606118
更新日期:2017-11-01 00:00:00
abstract::Locally advanced colorectal cancer is a challenge for surgeons and medical oncologist; 10 to 20% colorectal cancer debut as locally advanced disease, with tumors extending through the colon wall with perforation and/or invasion of adjacent organs or structures. Those locally advanced tumors have a worse prognostic at ...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0040-1713742
更新日期:2020-09-01 00:00:00
abstract::The use of drains in colorectal surgery has been a subject of debate for several decades. Prophylactic drainage of the peritoneal cavity has become less popular in recent years. This change is due to several studies demonstrating that intraperitoneal drains do not adequately drain the peritoneal cavity and do not prev...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0033-1351134
更新日期:2013-09-01 00:00:00
abstract::Large bowel obstruction is a common problem with many different causes, the most common being colorectal adenocarcinoma, extracolonic adenocarcinoma, diverticular disease, volvulus, and inflammatory bowel disease. The nature of the obstruction can influence the best management. Historically, treatment of obstruction c...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0032-1329533
更新日期:2012-12-01 00:00:00
abstract::In the United States, the prevalence of adenomatous polyps found during colonoscopic evaluation ranges from 25 to 41%, and of these, 2 to 5% contain invasive malignancy. The management of the malignant polyp continues to be challenging. Endoscopic resection by polypectomy has been shown to be sufficient for management...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-0028-1089944
更新日期:2008-11-01 00:00:00
abstract::Colorectal surgery patients frequently suffer from postoperative complications. Patients with complications have been shown to be at higher risk for mortality, poor oncologic outcomes, additional complications, and worse quality of life. Complications are increasingly recognized as markers of quality of care with more...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1584501
更新日期:2016-09-01 00:00:00
abstract::Colorectal cancer is common in the Western world; ~5% of individuals diagnosed with colorectal cancer have an identifiable inherited genetic predisposition to this malignancy. Genetic testing and rational clinical management recommendations currently exist for the management of individuals with a variety of colorectal...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-0029-1242459
更新日期:2009-11-01 00:00:00
abstract::Clinical research (CR) is a natural corollary to clinical surgery. It gives an investigator the opportunity to critically review their results and develop new strategies. This article covers the critical factors and the important components of a successful CR program. The first and most important step is to build a de...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0034-1376171
更新日期:2014-06-01 00:00:00
abstract::This article provides an overview of hidradenitis suppurativa, lichen planus, lichen sclerosis, calcinosis cuti, pyogenic granuloma, intertrigo, and seborrheic keratosis. This article also focuses on recognition and management of these pleomorphic afflictions of the perianal region. ...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1687836
更新日期:2019-09-01 00:00:00
abstract::The use of laparoscopy has become widespread across many surgical specialties. Its utility as treatment for colon cancer was initially met with hesitancy due to concern for port site and wound recurrences; however, this was later disproven by large retrospective series. Subsequently, there have been multiple, large, p...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1597317
更新日期:2017-04-01 00:00:00
abstract::The incidence of Crohn's disease in the pediatric population is increasing. While pediatric patients with Crohn's disease exhibit many of the characteristics of older patients, there are important differences in the clinical presentation and course of disease that can impact the clinical decisions made during treatmen...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1609022
更新日期:2018-03-01 00:00:00
abstract::Pruritus ani is a common condition with many different potential causes. Because of this, it can be difficult to treat. It is important to identify and eliminate any inciting factors, which are often unintentional consequences of the patient's attempts to alleviate symptoms. If no reversible cause is found, simple mea...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0035-1570391
更新日期:2016-03-01 00:00:00
abstract::Evidence-based medicine (EBM) is increasingly important for clinical surgery and for promotion of best practices into surgical decision making. Although barriers exist in the current surgical literature, for certain surgical scenarios, formal efforts to promote evidence-based surgery (EBS) into surgical education are ...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-0032-1322552
更新日期:2012-09-01 00:00:00
abstract::Genitourinary structures are at risk of injury during colorectal surgery. The incidence of injury is low; however, the risk is higher in cases involving severe inflammatory or infectious processes, locally advanced or recurrent cancer, previous radiation, and reoperation. Consideration of the anatomical relationship b...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1580629
更新日期:2016-06-01 00:00:00
abstract::A dynamic evolution is occurring in transanal surgery. Transanal techniques began with intraluminal surgical removal of rectal masses and have progressed to transanal total mesorectal excision (taTME) for rectal cancer. TaTME was first performed in 2009 by Sylla, Rattner, Delgado, and Lacy. This article documents the ...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0039-3402779
更新日期:2020-05-01 00:00:00
abstract::Radiologic assessment plays a vital role in the management of diverticulitis. It not only helps in the diagnosis, but also helps to guide the management. As technology has progressed, different modalities have offered insight into the treatment of this disease process. Through various trials and studies, certain modal...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1607466
更新日期:2018-07-01 00:00:00
abstract::Crohn's disease represents a challenging operative dilemma. The nature of the disease increases the technical complexity of operations, their morbidity, and the likelihood of multiple operations. In this setting, the advantages of laparoscopic surgery, including shorter hospital stays, less adhesion formation, fewer w...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-2007-991033
更新日期:2007-11-01 00:00:00
abstract::This article provides an overview of the pathophysiology, causes, investigations, and management of high-output enterostomy and enterocutaneous fistula. High-output stoma and enterocutaneous fistula can result in intestinal failure and this is often fatal if not managed properly. The management involves reducing fluid...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0037-1598163
更新日期:2017-07-01 00:00:00
abstract::Lower gastrointestinal bleeding (LGIB) is a common entity encountered by the surgeon. Though most LGIB stops on its own, familiarity with the diagnoses and their treatments is critical to optimal patient care. Even in 2016, surgery may be required. Advances in imaging have led to an enhanced ability to localize bleedi...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1693439
更新日期:2020-01-01 00:00:00
abstract::The timing of elective surgery for the treatment of diverticular disease is constantly evolving. Historically, the indications for elective surgery were relatively consistent. It was recommended that patients undergo elective resection after two documented attacks of uncomplicated diverticulitis or after one attack of...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-0029-1236161
更新日期:2009-08-01 00:00:00
abstract::As a result of the obvious benefits of laparoscopic cholecystectomy, minimally invasive techniques have been applied to more complex gastrointestinal procedures, including colorectal resections. The goal in adapting laparoscopic techniques for colorectal surgery is to offer an operation that results in less pain, shor...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章
doi:10.1055/s-2005-916278
更新日期:2005-08-01 00:00:00
abstract::Crohn's disease is a complex disease with a varying clinical and anatomical spectrum. One-third of patients with Crohn's will have disease confined to the colon. In this article, the authors review the surgical treatment options for colonic Crohn's disease including the current status of performing segmental colectomy...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0039-1683906
更新日期:2019-07-01 00:00:00
abstract::A range of topics are covered in this issue dedicated to complex and reoperative colorectal surgery, from radiation-induced surgical problems, to enterocutaneous fistulas and locally advanced or recurrent rectal cancer. Common themes include the importance of operative planning and patient counseling on the expected f...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0036-1580634
更新日期:2016-06-01 00:00:00
abstract::The evolution over the past 20 years of anal preservation in rectal cancer surgery has been truly remarkable. Intersphincteric resection (ISR) reported by Schiessel in 1994 in Australia has been shown to enable anal preservation even for cancers quite close to the anus. In Japan, ISR via the detachment of the anal can...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0040-1714240
更新日期:2020-11-01 00:00:00
abstract::Fluid management is an essential component of the Enhanced Recovery after Surgery (ERAS) pathway. Optimal management begins in the preoperative period and continues through the intraoperative and postoperative phases. In this review, we outline current evidence-based practices for fluid management through each phase o...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1676476
更新日期:2019-03-01 00:00:00
abstract::Clostridium (reclassified as " Clostridioides ") difficile colitis is a common nosocomial infection associated with increased morbidity and mortality. Like many clinical encounters, a focused history and physical examination will help to guide initial management. Further laboratory testing will assist with diagnosis t...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0039-3400474
更新日期:2020-03-01 00:00:00
abstract::Peritoneal surface disease (PSD) has historically been used interchangeably with the term peritoneal carcinomatosis (PC) and has a dismal natural history. A variety of malignant pathologies, including colorectal and appendiceal primary tumors, can disseminate throughout the peritoneal cavity, leading to bowel obstruct...
journal_title:Clinics in colon and rectal surgery
pub_type: 杂志文章,评审
doi:10.1055/s-0038-1642052
更新日期:2018-09-01 00:00:00