Pitfalls in measuring high-density lipoprotein cholesterol concentrations in HIV-infected patients.

abstract：OBJECTIVES:We provide the first estimate of HIV prevalence among trans and gender-diverse people living in England and compare outcomes of people living with HIV according to gender identity. METHODS:We analysed a comprehensive national HIV cohort and a nationally representative self-reported survey of people accessin...

journal_title：HIV medicine

authors： Kirwan PD,Hibbert M,Kall M,Nambiar K,Ross M,Croxford S,Nash S,Webb L,Wolton A,Delpech VC

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:Dyslipidaemic effects of antiretrovirals (ARVs) may contribute to increased cardiovascular risk (CR) in HIV-1-infected patients. The ARTEN (atazanavir/ritonavir on a background of tenofovir and emtricitabine vs. nevirapine on the same background, in naïve HIV-1-infected patients) study compared prospectively...

journal_title：HIV medicine

authors： Podzamczer D,Andrade-Villanueva J,Clotet B,Taylor S,Rockstroh JK,Reiss P,Domingo P,Gellermann HJ,de Rossi L,Cairns V,Soriano V

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVES:Antiretroviral therapy (ART) in HIV-infected patients is associated with increased cardiovascular risk. Circulating markers of endothelial dysfunction may be used to study early atherogenesis. The aim of our study was to investigate changes in such markers during initiation of ART. METHODS:In 115 HIV-positi...

journal_title：HIV medicine

authors： Kristoffersen US,Kofoed K,Kronborg G,Giger AK,Kjaer A,Lebech AM

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:There is increasing in vitro and in vivo evidence that reduced zidovudine (ZDV) susceptibility is generated by the selective pressure conferred by other nucleoside reverse transcriptase inhibitors (NRTIs). However, the degree to which this occurs in clinical practice remains unclear. We assessed phenotypic a...

journal_title：HIV medicine

authors： Gilleece Y,Torti C,Mandalia S,Gazzard BG,Pillay D,Pozniak AL

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:It has been suggested that chronic hepatitis C virus (HCV) infection depletes mitochondrial DNA (mtDNA) in the liver. Because decreased mtDNA levels were also found in humans infected with HIV, we investigated whether HIV may have aggravated hepatic mtDNA depletion in individuals with HCV infection. METHODS...

journal_title：HIV medicine

authors： Bäuerle J,Laguno M,Mauss S,Mallolas J,Murillas J,Miquel R,Schmutz G,Setzer B,Gatell JM,Walker UA

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVES:Hepatitis C virus (HCV) has emerged as an important health problem in the era of effective HIV treatment. However, very few data exist on the health status and disease burden of HIV/HCV-coinfected Canadians. METHODS:HIV/HCV-coinfected patients were enrolled prospectively in a multicentre cohort from 16 cent...

journal_title：HIV medicine

authors： Klein MB,Rollet KC,Saeed S,Cox J,Potter M,Cohen J,Conway B,Cooper C,Côté P,Gill J,Haase D,Haider S,Hull M,Moodie E,Montaner J,Pick N,Rachlis A,Rouleau D,Sandre R,Tyndall M,Walmsley S,Canadian HIV-HCV Cohort Inve

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe a UK-wide process to assess adherence to guidelines for the routine investigation and monitoring of HIV-positive adults aged ≥ 50 years and provide clinical services with individual feedback to support improvement in quality of care. METHODS:The British HIV Association (...

journal_title：HIV medicine

authors： Ekong N,Curtis H,Ong E,Sabin CA,Chadwick D,British HIV Association (BHIVA) Audit and Standards Sub-Committee.

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to reconstruct the HIV epidemic in Australia for selected populations categorized by exposure route; namely, transmission among men who have sex with men (MSM), transmission among injecting drug users (IDUs), and transmission among heterosexual men and women in Australia. DESIGN:Sta...

journal_title：HIV medicine

authors： Wand H,Yan P,Wilson D,McDonald A,Middleton M,Kaldor J,Law M

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:Despite the huge success of antiretroviral therapy (ART), there is an ongoing HIV epidemic among men who have sex with men (MSM) in resource-rich countries. Understanding the driving factors underlying this process is important for curbing the epidemic. METHODS:We simulated the HIV epidemic in MSM in Switze...

journal_title：HIV medicine

authors： Kusejko K,Marzel A,Hampel B,Bachmann N,Nguyen H,Fehr J,Braun DL,Battegay M,Bernasconi E,Calmy A,Cavassini M,Hoffmann M,Böni J,Yerly S,Klimkait T,Perreau M,Rauch A,Günthard HF,Kouyos RD,Swiss HIV Cohort Study.

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to identify and describe the characteristics of persons born in the UK who acquire HIV infection abroad. METHODS:Analyses using case reports and follow-up data from the national HIV database held at the Health Protection Agency were performed. RESULTS:Fifteen per cent (2066 of 13 8...

journal_title：HIV medicine

authors： Rice B,Gilbart VL,Lawrence J,Smith R,Kall M,Delpech V

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:GB virus type C (GBV-C) viraemia is associated with a beneficial outcome in HIV-infected individuals in several though not all studies. GBV-C viraemia was examined in a matched case-control study of 133 HIV-infected pregnant women who transmitted HIV to their infants ('cases') and 266 non-transmitting contro...

journal_title：HIV medicine

authors： Handelsman E,Cheng I,Thompson B,Hershow R,Mofenson LM,Hollinger FB,Chen KT,Burchett SK,Klinzman D,Stapleton JT,Women and Infants Transmission Study Group (WITS).

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVES:Outbreaks of shigellosis have been documented in men who have sex with men (MSM), associated with interpersonal transmission and underlying HIV infection. We observed a rise in Shigella flexneri isolates identified in a downtown tertiary-care hospital laboratory located within the city centre community healt...

journal_title：HIV medicine

authors： Wilmer A,Romney MG,Gustafson R,Sandhu J,Chu T,Ng C,Hoang L,Champagne S,Hull MW

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:Based on the short-term results of the AIDS Clinical Trials Group (ACTG) A5095 trial, zidovudine (ZDV)/lamivudine (3TC)/abacavir (ABC) is no longer recommended as a first-line antiretroviral regimen. Data on the efficacy of this triple nucleoside reverse transcriptase inhibitor (NRTI) combination compared wit...

journal_title：HIV medicine

authors： Cuzin L,Pugliese P,Bugnon F,Delpierre C,Cua E,Billaud E,Massip P,Raffi F,Dellamonica P

更新日期：2005-11-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to identify differences in infant outcomes, virological efficacy, and preterm delivery (PTD) outcome between women exposed to lopinavir/ritonavir (LPV/r) and those exposed to atazanavir/ritonavir (ATV/r). METHODS:A retrospective case note review was carried out. The case notes of 49...

journal_title：HIV medicine

authors： Perry ME,Taylor GP,Sabin CA,Conway K,Flanagan S,Dwyer E,Stevenson J,Mulka L,McKendry A,Williams E,Barbour A,Dermont S,Roedling S,Shah R,Anderson J,Rodgers M,Wood C,Sarner L,Hay P,Hawkins D,deRuiter A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Virological failure of first-generation nonnucleoside reverse transcriptase inhibitors (NNRTIs) can compromise the efficacy of etravirine as a result of the accumulation of NNRTI resistance mutations. How quickly NNRTI resistance accumulates in patients with a delayed switch from nevirapine or efavirenz desp...

journal_title：HIV medicine

authors： Cozzi-Lepri A,Paredes,Phillips AN,Clotet B,Kjaer J,Von Wyl V,Kronborg G,Castagna A,Bogner JR,Lundgren JD,EuroSIDA in EuroCoord.

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:To audit clinical and surrogate marker outcome data following the introduction of combination antiretroviral therapy to HIV-infected children in South London. METHODS:We performed a retrospective cohort study of 110 HIV-infected children under the care of the Paediatric HIV in South London Network (PHILS-NE...

journal_title：HIV medicine

authors： Doerholt K,Sharland M,Ball C,DuMont G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Direct-acting antiviral agents (DAAs) have become the standard of care for the treatment of chronic hepatitis C virus (HCV) infection. We aimed to assess treatment uptake and efficacy in routine clinical settings among HIV/HCV coinfected patients after the introduction of the first generation DAAs. METHODS:...

journal_title：HIV medicine

authors： Schaerer V,Haubitz S,Kovari H,Ledergerber B,Ambrosioni J,Cavassini M,Stoeckle M,Schmid P,Decosterd L,Aouri M,Böni J,Günthard HF,Furrer H,Metzner KJ,Fehr J,Rauch A,Swiss HIV Cohort Study.

更新日期：2015-11-01 00:00:00

abstract：:Initiating antiretroviral therapy (ART) as early as the day of HIV diagnosis is a strategy of increasing global interest to control the HIV epidemic and optimize the health of people living with HIV (PLWH). No detrimental effects of rapid-start ART have been identified in randomized controlled trials undertaken in low...

journal_title：HIV medicine

authors： Boyd MA,Boffito M,Castagna A,Estrada V

更新日期：2019-03-01 00:00:00

abstract：:We describe the characteristics of HIV post-exposure prophylaxis (PEP) recipients and PEP indications at 56 Dean Street, a central London sexual health clinic. PEP was prescribed on 577 occasions. Most (97%) was given for unprotected anal intercourse. Over a fifth of exposures involved recreational drug use. Of the pa...

journal_title：HIV medicine

authors： Whitlock G,Nwokolo N,McOwan A

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:Certain non-AIDS-related diseases have been associated with immunodeficiency and HIV RNA levels in HIV-infected patients on combination antiretroviral therapy (cART). We aimed to investigate these associations in patients not yet on cART, when potential antiretroviral-drug-related effects are absent and vari...

journal_title：HIV medicine

authors： Zhang S,van Sighem A,Kesselring A,Gras L,Prins JM,Hassink E,Kauffmann R,Richter C,de Wolf F,Reiss P,ATHENA national observational HIV cohort study.

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Recent studies in hospitalized patients with community-acquired pneumonia have found a lower risk of bacteraemia and better clinical outcomes in patients who had previously received the 23-valent pneumococcal polysaccharide vaccine (PPV) in comparison with unvaccinated individuals. The aim of this study was ...

journal_title：HIV medicine

authors： Imaz A,Falcó V,Peñaranda M,Jordano Q,Martínez X,Nadal C,Curran A,Planes AM,Dalmau D,Ribera E,Riera M,Ruiz de Gopegui E,Pahissa A

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVES:To assess second-line antiretroviral therapy (ART) virological failure and HIV drug resistance-associated mutations (RAMs), in support of third-line regimen planning in Asia. METHODS:Adults > 18 years of age on second-line ART for ≥ 6 months were eligible. Cross-sectional data on HIV viral load (VL) and gen...

journal_title：HIV medicine

authors： Ross J,Jiamsakul A,Kumarasamy N,Azwa I,Merati TP,Do CD,Lee MP,Ly PS,Yunihastuti E,Nguyen KV,Ditangco R,Ng OT,Choi JY,Oka S,Sohn AH,Law M

更新日期：2020-11-05 00:00:00

abstract：OBJECTIVE:The aim of the study was to compare the incidence of anaemia in patients treated with zidovudine (ZDV) with that in patients treated with highly active antiretroviral therapy (HAART) not including ZDV. METHODS:Using HIV Insight, a database of abstracted US HIV care centre medical charts, ZDV-naïve patients s...

journal_title：HIV medicine

authors： Curkendall SM,Richardson JT,Emons MF,Fisher AE,Everhard F

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to compare the metabolic and morphological effects of enfuvirtide plus an optimized background (OB) regimen vs. OB alone (control group) in treatment-experienced patients in the T-20 vs. Optimized Regimen Only (TORO) studies. METHODS:Body composition and metabolic changes were invest...

journal_title：HIV medicine

authors： Cooper DA,Cordery DV,Reiss P,Henry K,Nelson M,O'Hearn M,Reynes J,Arastéh K,Chung J,Rowell L,Guimaraes D,Bertasso A,TORO 1 and TORO 2 Study Groups.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:TMC125-C227, an exploratory phase II, randomized, controlled, open-label trial, compared the efficacy and safety of TMC125 (etravirine) with an investigator-selected protease inhibitor (PI) in nonnucleoside reverse transcriptase inhibitor (NNRTI)-resistant, protease inhibitor-naïve, HIV-1-infected patients. ...

journal_title：HIV medicine

authors： Ruxrungtham K,Pedro RJ,Latiff GH,Conradie F,Domingo P,Lupo S,Pumpradit W,Vingerhoets JH,Peeters M,Peeters I,Kakuda TN,De Smedt G,Woodfall B,TMC125-C227 study group.

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:Adipose tissue affects several aspects of the cellular immune system, but prior epidemiological studies have differed on whether a higher body mass index (BMI) promotes CD4 T-cell recovery on antiretroviral therapy (ART). The objective of this analysis was to assess the relationship between BMI at ART initia...

journal_title：HIV medicine

authors： Koethe JR,Jenkins CA,Lau B,Shepherd BE,Silverberg MJ,Brown TT,Blashill AJ,Anema A,Willig A,Stinnette S,Napravnik S,Gill J,Crane HM,Sterling TR,North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD).

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:A prospective study was carried out to assess HIV-1 and HIV-2 mother-to-child transmission (MTCT) rates in Portugal between 1999 and 2005 by analysing the proportion of diagnosed infected children born to HIV-positive mothers. MATERIALS AND METHODS:Serial blood samples were collected from 1315 children at ri...

journal_title：HIV medicine

authors： Pádua E,Almeida C,Nunes B,Cortes Martins H,Castela J,Neves C,Paixão MT

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVES:To evaluate the benefits of therapeutic drug monitoring (TDM) in association with genotypic resistance testing and expert advice to optimize therapy in multiexperienced patients infected with HIV-1. METHODS:Patients with a viral load>1000 HIV-1 RNA copies/mL and an unchanged antiretroviral therapy regimen o...

journal_title：HIV medicine

authors： Bossi P,Peytavin G,Ait-Mohand H,Delaugerre C,Ktorza N,Paris L,Bonmarchand M,Cacace R,David DJ,Simon A,Lamotte C,Marcelin AG,Calvez V,Bricaire F,Costagliola D,Katlama C

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:In order to estimate HIV incidence among high-risk groups, in January 2009 the Health Protection Agency introduced the Recent Infection Testing Algorithm (RITA) in England and Northern Ireland (E&NI), currently the only regions to inform patients of RITA results. This survey of HIV specialists aimed to inves...

journal_title：HIV medicine

authors： Garrett Nj,Lattimore S,Gilbart V,Aghaizu A,Mensah G,Tosswill J,Murphy G,Delpech V

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to examine the prevalence of HIV infection in patients presenting in primary care with glandular fever (GF)-like illness. METHODS:Samples from primary care submitted for a GF screen between April 2009 and June 2010 were identified. Samples without an HIV request were anonymized and ...

journal_title：HIV medicine

authors： Hsu DT,Ruf M,O'Shea S,Costelloe S,Peck J,Tong CY

更新日期：2013-01-01 00:00:00