Abstract:
:Although the prognoses of children with medulloblastoma have improved dramatically over the last several decades, the reported survival for very young children with this tumor remains poor. We undertook a retrospective review of patients less than 36 months of age at the time of the diagnosis of a medulloblastoma who were treated at our institution during a 36-year period. Of 28 such patients, 10 patients are presently surviving without disease at a median of 150 months from diagnosis. The presence of a metastatic tumor at the time of diagnosis was identified as a significant indicator of a poor prognosis, and all completely staged patients without metastasis are surviving without a recurrence of disease. This report suggests that the survival of very young children with a medulloblastoma may not be as poor as has been previously reported, particularly if a disseminated tumor is not present at the time of diagnosis.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Geyer R,Levy M,Berger MS,Milstein J,Griffin B,Bleyer WAsubject
Has Abstractpub_date
1991-11-01 00:00:00pages
707-10; discussion 710-1issue
5eissn
0148-396Xissn
1524-4040journal_volume
29pub_type
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