Abstract:
:Iodine metabolism and kinetics in thyroid carcinoma cells may be different from that in normal thyroid tissue. The optimal time for performing post-therapeutic scans to detect metastatic lesions is still controversial.We retrospectively analyzed the images of 239 patients who received I-131 therapy at our hospital from January 2006 to May 2008. The therapeutic dose ranged from 1.1 GBq (30 mCi) to 7.4 GBq (200 mCi) and the patients received 3 sequential whole body scans on the third to fourth day, fifth to sixth day, and 10th-11th day after I-131 administration. We scored the I-131 avid lesions by visual assessment into 3 grades: 2=clearly visible; 1=visible; and 0=not visible. We also compared the thyroglobulin levels and FDG uptake among the lesions with probably different kinetics of iodine metabolism.In this study, there was a trend of decreasing visualization of lesions in the sequential images. Twenty-eight percent of lymph node metastases, 17% of lung metastases, and 16% of bone metastases were missed on the late images on 10-11th day. On the other hand, only 5% of the remnants were missed. The ratio of early washout was different between remnants and metastatic lesions. The serum thyroglobulin levels and FDG uptake did not correlate with early washout of the I-131 avid lesions. We concluded that earlier imaging is necessary for detection of metastatic lesions.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Hung BT,Huang SH,Huang YE,Wang PWdoi
10.1097/RLU.0b013e3181a345besubject
Has Abstractpub_date
2009-06-01 00:00:00pages
339-42issue
6eissn
0363-9762issn
1536-0229pii
00003072-200906000-00001journal_volume
34pub_type
杂志文章abstract::Hemangiomas are easily, quickly and relatively noninvasively detected using whole-body imaging with Tc-99m labeled RBCs. A case in which this method was used to confirm known lesions and detect additional unsuspected lesions is described. This method can also be useful in the detection and evaluation of other types of...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198610000-00012
更新日期:1986-10-01 00:00:00
abstract::67Ga-citrate scan from skull to mid-abdomen showed increased uptake in both parotid glands, mediastinum, lungs, uvei and/or enlarged lacrimal glands. The differential diagnosis of the positive radiogallium scan is discussed with emphasis on the value of the extrathoracic findings. Tissue diagnosis confirmed the imagin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197804000-00001
更新日期:1978-04-01 00:00:00
abstract:AIM:The present study was aimed to determine the efficacy of integrated FDG PET/CT in patients with gallbladder cancer (GBC) with suspicion of recurrent disease. METHODS:A total of 49 patients (male: 15, female: 34; median age: 52.5 years) with GBC underwent FDG PET/CT for suspected recurrence. A total of 62 PET/CT sc...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e31824d24c4
更新日期:2012-05-01 00:00:00
abstract::A prospective study of eight patients with recent transmural myocardial infarction was performed using 99mTc-Sn-pyrophosphate and 99mTc-Sn-methylene diphosphonate in each patient. All pyrophosphate scans were strongly positive whereas the diphosphonate scan was strongly positive in only one case. We conclude that 99mT...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197903000-00001
更新日期:1979-03-01 00:00:00
abstract::C-methionine (MET) positron emission tomography (PET) is more sensitive than F-fluorodeoxyglucose (FDG)-PET for detecting myeloma lesion. Many clinical studies support this evidence mainly for multiple myeloma cases of IgG or IgA subtypes. However, this is not confirmed for low monoclonal protein-producing myelomas, s...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001821
更新日期:2017-11-01 00:00:00
abstract::A 30-year-old woman presented with a painless left upper neck swelling for more than a week. Fibrolaryngoscope examination suggested nasopharyngeal carcinoma. FDG PET/CT was performed for an initial staging, which revealed intense activity in the soft tissue mass in the nasopharynx and cervical lymph nodes. However, b...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000656
更新日期:2015-06-01 00:00:00
abstract::To evaluate whether a prolonged infusion of Tc-99m sestamibi allows for visualization of viable myocardium in areas of hypoperfused myocardium, 25 patients were prospectively studied. Each patient was imaged four times in two consecutive days in the following manner: day 1:1) immediately after injection of Tl-201 at r...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199505000-00014
更新日期:1995-05-01 00:00:00
abstract::A case of false-negative Tc-99m MDP bone scintigrams, taken at one and two weeks for pathologic fractures in a patient with metabolic bone disease and a super-scan appearance, is described. The patient had renal osteodystrophy, and postparathyroidectomy hypocalcemia. Postoperative seizures caused multiple pathologic f...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198707000-00004
更新日期:1987-07-01 00:00:00
abstract::A total of 66 patients with advanced coronary artery disease (CAD) and 36 with dilated cardiomyopathies (DCM) with ejection fractions less than 20% were analyzed retrospectively to establish patterns of wall motion in each of four quadrants on standard left anterior oblique gated radionuclide ventriculograms. In both ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198709000-00017
更新日期:1987-09-01 00:00:00
abstract::Hepatobiliary scans are performed frequently to identify gallbladder-related disease. Although gallbladder stones are a common cause of hepatobiliary disease, they are visualized directly only rarely on hepatobiliary scans. Large gallbladder stones produced a photopenic defect in the gallbladder in a hepatobiliary sca...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200101000-00027
更新日期:2001-01-01 00:00:00
abstract:AIM:The purpose of this study was to conduct a systematic review of the published literature to assess the role (indications, advantages, and limitations) of SPECT/CT for the detection of sentinel lymph node (SLN) in breast cancer. METHODS:The authors searched PubMed for published literature in English addressing this...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章,meta分析
doi:10.1097/RLU.0b013e31829af8c0
更新日期:2014-05-01 00:00:00
abstract::Radionuclide angiography of the abdominal aorta provides hemodynamic information of the kidneys, aorta and aneurysm as well as the location and extent of aneurysm. Visualization of early abnormal activity in the pelvic region simultaneously with iliac artery visualization is thought to be a specific finding of active ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-197807000-00003
更新日期:1978-07-01 00:00:00
abstract::An additional case of wandering spleen is reported. A brief review of the etiology of this entity, as well as various findings obtained with nuclear imaging of the spleen, is presented. The authors discuss the relevance of repeated spleen scans to the clinical decision making process. Particular significance is paid t...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198111000-00005
更新日期:1981-11-01 00:00:00
abstract::Takayasu's disease (pulseless disease) is an uncommon chronic inflammatory disease primarily affecting the medium and large arteries, with a strong predilection for the aortic arch and its branches; hence, it sometimes is referred to as aortic arch syndrome. The etiology is unknown, although a systemic immunologic pro...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199309000-00002
更新日期:1993-09-01 00:00:00
abstract::The images of a patient with acromegaly, who previously underwent operation for pituitary adenoma, were obtained. The MRI scan showed a mass in the right cavernous sinus, with biochemical test results positive for the presence of a hormonally active adenoma. The patient was scheduled for CyberKnife radiotherapy. Radio...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000535
更新日期:2014-12-01 00:00:00
abstract:PURPOSE:This study was designed to determine the outcomes of patients referred to the authors' nuclear medicine service for dosimetric evaluation and treatment of metastatic thyroid cancer with radioiodine I-131. In addition, the incidence and severity of hematologic toxicity associated with treatment were determined. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-200208000-00003
更新日期:2002-08-01 00:00:00
abstract::Venous malformations of the parotid glands are uncommon and can be difficult to confirm on routine anatomical imaging alone because of overlap of imaging features with other more common parotid lesions. (99m)Tc RBC scans combined with SPECT/CT offer a noninvasive way to diagnose parotid venous malformations without th...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000000792
更新日期:2015-07-01 00:00:00
abstract::Xerostomia is a significant morbidity of radiation treatment in the management of head and neck cancers. To preserve salivary function, a surgical technique has been developed that involves the transfer of one submandibular gland to the ipsilateral submental space, where it can be shielded during radiation therapy. F-...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e318219ac4a
更新日期:2011-08-01 00:00:00
abstract:PURPOSE:This pilot study aimed to prove the complementary value of a novel Gallium-labeled heterodimeric peptide, Ga-NOTA-3P-TATE-RGD, in detection and evaluation of tumors with somatostatin receptor subtype 2 or integrin αvβ3 overexpression, including non-small cell lung cancer (NSCLC), small-cell lung cancer (SCLC), ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002680
更新日期:2019-09-01 00:00:00
abstract::The speed of Tc-99m DTPA/HMPAO radioaerosol clearance from the lungs that is represented as a slope from lungs to blood was measured in 23 male normal controls using commercial lung radioaerosol delivery units in the supine position in order to avoid the influences of gravity. The right lung was selected and three reg...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-199507000-00016
更新日期:1995-07-01 00:00:00
abstract::Intense muscle localization of Tc-99m MDP to upper extremity musculature was noted three days following weight lifting exercises. This phenomenon is due to an unknown mechanism although several causative factors have been suggested. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198705000-00003
更新日期:1987-05-01 00:00:00
abstract::Brucellosis is an endemic disease in the Middle East. Its incidence in Kuwait has increased during the last 5 years. Bone and joint involvement causes major symptoms and disabilities. Radionuclide bone scans are more sensitive than radiographs in detecting these lesions. The aim of this study is to describe the abnorm...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198802000-00008
更新日期:1988-02-01 00:00:00
abstract::A 32-month-old female child with a history of stage IV favorable biology neuroblastoma with a 123-I MIBG (metaiodobenzylguanidine scan) avid adrenal mass, with retroperitoneal nodal extension and bony metastasis, was in complete remission after intense multimodal therapy. Seventeen months after diagnosis a surveillanc...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3181ea3502
更新日期:2010-09-01 00:00:00
abstract:: A 50-year-old-man with abdominal pain, who had undergone aortic aneurysm reconstructive surgery (aortic graft) 3 years before, was admitted to the hospital. A CT scan showed findings suggestive of perigraft infection. Scintigraphy with 99mTc-hexamethylpropylene amine oxime (HMPAO)-labeled leukocytes confirmed the dia...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0b013e3182639bd9
更新日期:2012-11-01 00:00:00
abstract::There are occasional reports of a hiatal hernia demonstrating thoracic uptake on I-131 scintigraphy. This is a cause of a potential false-positive appearance mimicking a pulmonary or mediastinal metastasis. Hiatal hernia is 1 of a number of causes of false-positive I-131 whole-body scans. Although previous case report...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.RLU.0000079663.56340.18
更新日期:2003-08-01 00:00:00
abstract::Bone scintigraphy is sensitive for detecting bone metastases in patients with malignancies. However, it is often difficult to differentiate bone metastases from other nonmalignant lesions. We encountered a patient with a history of breast cancer who showed substantial elevation of tumor markers 4 years after surgery. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/01.rlu.0000170058.73956.82
更新日期:2005-08-01 00:00:00
abstract::A 26-year-old man had unilateral facial numbness. A brain MRI suggested possible brain metastases. F-FDG and C-choline PET/CT revealed multiple sites of abnormal activity in the body. However, C-choline PET/CT was more impressive than FDG PET/CT. Especially, the brain lesions revealed by MRI had only elevated C-cholin...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000001324
更新日期:2016-10-01 00:00:00
abstract::A variety of congenital and acquired etiologies can give rise to the radiographic finding of a unilateral hyperlucent lung. An unusual case of congenital lobar emphysema diagnosed in a young adult following the initial discovery of a hyperexpanded, hyperlucent lung is reported. Although subsequent bronchoscopy and rad...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:
更新日期:1990-10-01 00:00:00
abstract::Two cases of unilateral septic sacro-iliitis are reported. Importance of the anterior view of sacroiliac joints on the radionuclide bone scan is stressed. Limitation of the posterior view in evaluation of sacroiliac joints may lead to misdiagnosis and false negative results in unilateral sacro-illiac disease. ...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/00003072-198309000-00006
更新日期:1983-09-01 00:00:00
abstract::Breast cancer is the most common cancer in women with rising incidence worldwide. F-FDG PET/CT imaging has already established itself as a pivotal modality for staging, restating and response assessment in patients with carcinoma breast. The complex biology of this cancer is increasingly being decoded and various mole...
journal_title:Clinical nuclear medicine
pub_type: 杂志文章
doi:10.1097/RLU.0000000000002783
更新日期:2020-02-01 00:00:00