Appropriate time for post-therapeutic I-131 whole body scan.

Abstract:

:Iodine metabolism and kinetics in thyroid carcinoma cells may be different from that in normal thyroid tissue. The optimal time for performing post-therapeutic scans to detect metastatic lesions is still controversial.We retrospectively analyzed the images of 239 patients who received I-131 therapy at our hospital from January 2006 to May 2008. The therapeutic dose ranged from 1.1 GBq (30 mCi) to 7.4 GBq (200 mCi) and the patients received 3 sequential whole body scans on the third to fourth day, fifth to sixth day, and 10th-11th day after I-131 administration. We scored the I-131 avid lesions by visual assessment into 3 grades: 2=clearly visible; 1=visible; and 0=not visible. We also compared the thyroglobulin levels and FDG uptake among the lesions with probably different kinetics of iodine metabolism.In this study, there was a trend of decreasing visualization of lesions in the sequential images. Twenty-eight percent of lymph node metastases, 17% of lung metastases, and 16% of bone metastases were missed on the late images on 10-11th day. On the other hand, only 5% of the remnants were missed. The ratio of early washout was different between remnants and metastatic lesions. The serum thyroglobulin levels and FDG uptake did not correlate with early washout of the I-131 avid lesions. We concluded that earlier imaging is necessary for detection of metastatic lesions.

journal_name

Clin Nucl Med

authors

Hung BT,Huang SH,Huang YE,Wang PW

doi

10.1097/RLU.0b013e3181a345be

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

339-42

issue

6

eissn

0363-9762

issn

1536-0229

pii

00003072-200906000-00001

journal_volume

34

pub_type

杂志文章
  • Detection of hemangiomas using whole-body imaging with technetium-99m labeled RBCs.

    abstract::Hemangiomas are easily, quickly and relatively noninvasively detected using whole-body imaging with Tc-99m labeled RBCs. A case in which this method was used to confirm known lesions and detect additional unsuspected lesions is described. This method can also be useful in the detection and evaluation of other types of...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198610000-00012

    authors: Hollerman JJ,Bernstein MA,Froelich JW,Schkudor G

    更新日期:1986-10-01 00:00:00

  • Diagnosis of uveo-parotid fever by 67Ga-citrate imaging.

    abstract::67Ga-citrate scan from skull to mid-abdomen showed increased uptake in both parotid glands, mediastinum, lungs, uvei and/or enlarged lacrimal glands. The differential diagnosis of the positive radiogallium scan is discussed with emphasis on the value of the extrathoracic findings. Tissue diagnosis confirmed the imagin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197804000-00001

    authors: Oren VO,Uszler JM,White J

    更新日期:1978-04-01 00:00:00

  • Role of 18F-FDG PET/CT in detecting recurrent gallbladder carcinoma.

    abstract:AIM:The present study was aimed to determine the efficacy of integrated FDG PET/CT in patients with gallbladder cancer (GBC) with suspicion of recurrent disease. METHODS:A total of 49 patients (male: 15, female: 34; median age: 52.5 years) with GBC underwent FDG PET/CT for suspected recurrence. A total of 62 PET/CT sc...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e31824d24c4

    authors: Kumar R,Sharma P,Kumari A,Halanaik D,Malhotra A

    更新日期:2012-05-01 00:00:00

  • Myocardial infarct imaging with 99mTc-pyrophosphate and 99mTc-methylene diphosphonate: lack of correlation.

    abstract::A prospective study of eight patients with recent transmural myocardial infarction was performed using 99mTc-Sn-pyrophosphate and 99mTc-Sn-methylene diphosphonate in each patient. All pyrophosphate scans were strongly positive whereas the diphosphonate scan was strongly positive in only one case. We conclude that 99mT...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197903000-00001

    authors: Makler PT Jr,Lederman S,Charkes ND,Malmud LS,Warner H,Reilley JJ

    更新日期:1979-03-01 00:00:00

  • Methionine PET Might Be Reliable for the Detection of Low M-Protein-Producing Myelomas.

    abstract::C-methionine (MET) positron emission tomography (PET) is more sensitive than F-fluorodeoxyglucose (FDG)-PET for detecting myeloma lesion. Many clinical studies support this evidence mainly for multiple myeloma cases of IgG or IgA subtypes. However, this is not confirmed for low monoclonal protein-producing myelomas, s...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001821

    authors: Imataki O,Uchida S,Yokokura S,Uemura M,Kadowaki N

    更新日期:2017-11-01 00:00:00

  • Nasopharyngeal tuberculosis mimicking nasopharyngeal carcinoma on (18)F-FDG PET/CT in a young patient.

    abstract::A 30-year-old woman presented with a painless left upper neck swelling for more than a week. Fibrolaryngoscope examination suggested nasopharyngeal carcinoma. FDG PET/CT was performed for an initial staging, which revealed intense activity in the soft tissue mass in the nasopharynx and cervical lymph nodes. However, b...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000656

    authors: Zhang Y,Chen Y,Huang Z,Cai L,Wu J

    更新日期:2015-06-01 00:00:00

  • Use of Tc-99m sestamibi infusion for detection of hibernating myocardium. A preliminary report.

    abstract::To evaluate whether a prolonged infusion of Tc-99m sestamibi allows for visualization of viable myocardium in areas of hypoperfused myocardium, 25 patients were prospectively studied. Each patient was imaged four times in two consecutive days in the following manner: day 1:1) immediately after injection of Tl-201 at r...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199505000-00014

    authors: Miron SD,Finkelhor R,Bahler R,Sodee DB,Bellon EM

    更新日期:1995-05-01 00:00:00

  • Pathologic fractures in a patient with renal osteodystrophy. Failure of early detection on bone scans.

    abstract::A case of false-negative Tc-99m MDP bone scintigrams, taken at one and two weeks for pathologic fractures in a patient with metabolic bone disease and a super-scan appearance, is described. The patient had renal osteodystrophy, and postparathyroidectomy hypocalcemia. Postoperative seizures caused multiple pathologic f...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198707000-00004

    authors: Campeau RJ,Bellah RD,Varma DG

    更新日期:1987-07-01 00:00:00

  • The last surviving wall.

    abstract::A total of 66 patients with advanced coronary artery disease (CAD) and 36 with dilated cardiomyopathies (DCM) with ejection fractions less than 20% were analyzed retrospectively to establish patterns of wall motion in each of four quadrants on standard left anterior oblique gated radionuclide ventriculograms. In both ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198709000-00017

    authors: Boykin M,Hartshorne MF,Bauman JM,Byrd BF

    更新日期:1987-09-01 00:00:00

  • Gallbladder stone shown on a hepatobiliary scan.

    abstract::Hepatobiliary scans are performed frequently to identify gallbladder-related disease. Although gallbladder stones are a common cause of hepatobiliary disease, they are visualized directly only rarely on hepatobiliary scans. Large gallbladder stones produced a photopenic defect in the gallbladder in a hepatobiliary sca...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200101000-00027

    authors: Sinha P,Krumm R,Mozley PD

    更新日期:2001-01-01 00:00:00

  • Role of SPECT/CT in sentinel lymph node detection in patients with breast cancer.

    abstract:AIM:The purpose of this study was to conduct a systematic review of the published literature to assess the role (indications, advantages, and limitations) of SPECT/CT for the detection of sentinel lymph node (SLN) in breast cancer. METHODS:The authors searched PubMed for published literature in English addressing this...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章,meta分析

    doi:10.1097/RLU.0b013e31829af8c0

    authors: Vercellino L,Ohnona J,Groheux D,Slama A,Colletti PM,Chondrogiannis S,Merlet P,Toubert ME,Rubello D

    更新日期:2014-05-01 00:00:00

  • Detection of active bleeding from ruptured aortic aneurysm by emergency radionuclide angiography.

    abstract::Radionuclide angiography of the abdominal aorta provides hemodynamic information of the kidneys, aorta and aneurysm as well as the location and extent of aneurysm. Visualization of early abnormal activity in the pelvic region simultaneously with iliac artery visualization is thought to be a specific finding of active ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-197807000-00003

    authors: Bunko H,Seto H,Tonami N,Hisada K

    更新日期:1978-07-01 00:00:00

  • Sequential liver-spleen scanning for documentation of wandering spleen.

    abstract::An additional case of wandering spleen is reported. A brief review of the etiology of this entity, as well as various findings obtained with nuclear imaging of the spleen, is presented. The authors discuss the relevance of repeated spleen scans to the clinical decision making process. Particular significance is paid t...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198111000-00005

    authors: Barnett SM,Poole JR,Briggs RC

    更新日期:1981-11-01 00:00:00

  • Clinical application of captopril renal scintigraphy in Takayasu's arteritis.

    abstract::Takayasu's disease (pulseless disease) is an uncommon chronic inflammatory disease primarily affecting the medium and large arteries, with a strong predilection for the aortic arch and its branches; hence, it sometimes is referred to as aortic arch syndrome. The etiology is unknown, although a systemic immunologic pro...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199309000-00002

    authors: Balingit AG,Anderson JH

    更新日期:1993-09-01 00:00:00

  • CyberKnife radiosurgery planning of a secreting pituitary adenoma performed with ⁶⁸Ga DOTATATE PET and MRI.

    abstract::The images of a patient with acromegaly, who previously underwent operation for pituitary adenoma, were obtained. The MRI scan showed a mass in the right cavernous sinus, with biochemical test results positive for the presence of a hormonally active adenoma. The patient was scheduled for CyberKnife radiotherapy. Radio...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000535

    authors: d'Amico A,Stąpór-Fudzińska M,Tarnawski R

    更新日期:2014-12-01 00:00:00

  • Outcome and toxicity associated with maximum safe dose radioiodine treatment of metastatic thyroid cancer.

    abstract:PURPOSE:This study was designed to determine the outcomes of patients referred to the authors' nuclear medicine service for dosimetric evaluation and treatment of metastatic thyroid cancer with radioiodine I-131. In addition, the incidence and severity of hematologic toxicity associated with treatment were determined. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-200208000-00003

    authors: Robeson WR,Ellwood JE,Margulies P,Margouleff D

    更新日期:2002-08-01 00:00:00

  • Utility of (99m)Tc RBC Scintigraphy in Diagnosing Parotid Venous Malformations.

    abstract::Venous malformations of the parotid glands are uncommon and can be difficult to confirm on routine anatomical imaging alone because of overlap of imaging features with other more common parotid lesions. (99m)Tc RBC scans combined with SPECT/CT offer a noninvasive way to diagnose parotid venous malformations without th...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000000792

    authors: Patel R,Saad H,Srinivasan A,Brown RK

    更新日期:2015-07-01 00:00:00

  • Submandibular salivary gland transfer: a pitfall in head and neck imaging with F-18 FDG PET/CT.

    abstract::Xerostomia is a significant morbidity of radiation treatment in the management of head and neck cancers. To preserve salivary function, a surgical technique has been developed that involves the transfer of one submandibular gland to the ipsilateral submental space, where it can be shielded during radiation therapy. F-...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e318219ac4a

    authors: Makis W,Ciarallo A,Abikhzer G,Rush C,Laufer J,Stern J

    更新日期:2011-08-01 00:00:00

  • Evaluation of Lung Cancer and Neuroendocrine Neoplasm in a Single Scan by Targeting Both Somatostatin Receptor and Integrin αvβ3.

    abstract:PURPOSE:This pilot study aimed to prove the complementary value of a novel Gallium-labeled heterodimeric peptide, Ga-NOTA-3P-TATE-RGD, in detection and evaluation of tumors with somatostatin receptor subtype 2 or integrin αvβ3 overexpression, including non-small cell lung cancer (NSCLC), small-cell lung cancer (SCLC), ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002680

    authors: Zheng Y,Wang H,Tan H,Cui X,Yao S,Zang J,Zhang L,Zhu Z

    更新日期:2019-09-01 00:00:00

  • Supine lung clearance of Tc-99m DTPA and HMPAO aerosols.

    abstract::The speed of Tc-99m DTPA/HMPAO radioaerosol clearance from the lungs that is represented as a slope from lungs to blood was measured in 23 male normal controls using commercial lung radioaerosol delivery units in the supine position in order to avoid the influences of gravity. The right lung was selected and three reg...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-199507000-00016

    authors: Kao CH,Lin HT,Yu SL,Wang SJ,Yeh SH

    更新日期:1995-07-01 00:00:00

  • Exercise-induced muscle uptake of technetium-99m MDP.

    abstract::Intense muscle localization of Tc-99m MDP to upper extremity musculature was noted three days following weight lifting exercises. This phenomenon is due to an unknown mechanism although several causative factors have been suggested. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198705000-00003

    authors: du Cret RP,Boudreau RJ,Block JB,Jensen PR,Loken MK

    更新日期:1987-05-01 00:00:00

  • Brucellosis: appearance on skeletal imaging.

    abstract::Brucellosis is an endemic disease in the Middle East. Its incidence in Kuwait has increased during the last 5 years. Bone and joint involvement causes major symptoms and disabilities. Radionuclide bone scans are more sensitive than radiographs in detecting these lesions. The aim of this study is to describe the abnorm...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198802000-00008

    authors: Bahar RH,Al-Suhaili AR,Mousa AM,Nawaz MK,Kaddah N,Abdel-Dayem HM

    更新日期:1988-02-01 00:00:00

  • False-positive MIBG uptake in pneumonia in a patient with stage IV neuroblastoma.

    abstract::A 32-month-old female child with a history of stage IV favorable biology neuroblastoma with a 123-I MIBG (metaiodobenzylguanidine scan) avid adrenal mass, with retroperitoneal nodal extension and bony metastasis, was in complete remission after intense multimodal therapy. Seventeen months after diagnosis a surveillanc...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3181ea3502

    authors: Schindler T,Yu C,Rossleigh M,Pereira J,Cohn R

    更新日期:2010-09-01 00:00:00

  • Incidental detection of gastrointestinal bleeding from an aortoenteric fistula on 99mTc leukocyte scintigraphy.

    abstract:: A 50-year-old-man with abdominal pain, who had undergone aortic aneurysm reconstructive surgery (aortic graft) 3 years before, was admitted to the hospital. A CT scan showed findings suggestive of perigraft infection. Scintigraphy with 99mTc-hexamethylpropylene amine oxime (HMPAO)-labeled leukocytes confirmed the dia...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0b013e3182639bd9

    authors: Cortés J,Villaverde J,Garrido M,Pombo M,Ruibal A

    更新日期:2012-11-01 00:00:00

  • Hiatal hernia in iodine-131 scintigraphy: a potential cause of false-positive midline thoracic uptake.

    abstract::There are occasional reports of a hiatal hernia demonstrating thoracic uptake on I-131 scintigraphy. This is a cause of a potential false-positive appearance mimicking a pulmonary or mediastinal metastasis. Hiatal hernia is 1 of a number of causes of false-positive I-131 whole-body scans. Although previous case report...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.RLU.0000079663.56340.18

    authors: Freeman M,Roach P,Robinson B,Shields M

    更新日期:2003-08-01 00:00:00

  • Bone metastasis detected by FDG PET in a patient with breast cancer and fibrous dysplasia.

    abstract::Bone scintigraphy is sensitive for detecting bone metastases in patients with malignancies. However, it is often difficult to differentiate bone metastases from other nonmalignant lesions. We encountered a patient with a history of breast cancer who showed substantial elevation of tumor markers 4 years after surgery. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/01.rlu.0000170058.73956.82

    authors: Shigesawa T,Sugawara Y,Shinohara I,Fujii T,Mochizuki T,Morishige I

    更新日期:2005-08-01 00:00:00

  • Differences in Uptake of 18F-FDG and 11C-Choline in a Case of Acute Myeloid Leukemia.

    abstract::A 26-year-old man had unilateral facial numbness. A brain MRI suggested possible brain metastases. F-FDG and C-choline PET/CT revealed multiple sites of abnormal activity in the body. However, C-choline PET/CT was more impressive than FDG PET/CT. Especially, the brain lesions revealed by MRI had only elevated C-cholin...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000001324

    authors: Qin C,Wu Z,Li J,Sun X,Lan X

    更新日期:2016-10-01 00:00:00

  • Ventilation-perfusion scintigraphy in an adult with congenital unilateral hyperlucent lung.

    abstract::A variety of congenital and acquired etiologies can give rise to the radiographic finding of a unilateral hyperlucent lung. An unusual case of congenital lobar emphysema diagnosed in a young adult following the initial discovery of a hyperexpanded, hyperlucent lung is reported. Although subsequent bronchoscopy and rad...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:

    authors: Wegener WA,Velchik MG

    更新日期:1990-10-01 00:00:00

  • Unilateral septic sacro-iliitis. Importance of the anterior view of the bone scan.

    abstract::Two cases of unilateral septic sacro-iliitis are reported. Importance of the anterior view of sacroiliac joints on the radionuclide bone scan is stressed. Limitation of the posterior view in evaluation of sacroiliac joints may lead to misdiagnosis and false negative results in unilateral sacro-illiac disease. ...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/00003072-198309000-00006

    authors: Kumar R,Balachandran S

    更新日期:1983-09-01 00:00:00

  • Breast Cancer Imaging With PET Based Radiopharmaceuticals Other Than 18F-FDG.

    abstract::Breast cancer is the most common cancer in women with rising incidence worldwide. F-FDG PET/CT imaging has already established itself as a pivotal modality for staging, restating and response assessment in patients with carcinoma breast. The complex biology of this cancer is increasingly being decoded and various mole...

    journal_title:Clinical nuclear medicine

    pub_type: 杂志文章

    doi:10.1097/RLU.0000000000002783

    authors: Vatsa R,Singh SS,Ashwathanarayana AG,Kumar R,Rana N,Shukla J,Mittal BR

    更新日期:2020-02-01 00:00:00