Heterogeneous expression of potassium currents and pacemaker currents potentially regulates arrhythmogenesis of pulmonary vein cardiomyocytes.

Abstract:

INTRODUCTION:The relationship between the determining factors and beating rates of pulmonary vein (PV) pacemaker cardiomyocytes has not been fully elucidated. The purposes of this study were to compare the electrophysiological characteristics between PV fast and slow pacemaker cardiomyocytes. METHODS:Whole-cell patch clamp was used to investigate the action potentials, transient outward currents (I(to)), sustained outward potassium currents (I(Ksus)), rapid delayed rectifier potassium currents (I(Kr)), inward rectifier potassium current (I(K1)), pacemaker currents (I(f)), and transient inward currents in isolated rabbit PV single fast (> or =2.5 Hz) and slow (<2.5 Hz) pacemaker cardiomyocytes. RESULTS:The fast PV pacemaker cardiomyocytes (n = 66) had lesser negative maximum diastolic potential (-53 +/- 1 mV vs -59 +/- 1 mV, P < 0.001) and larger slope of diastolic depolarization (0.31 +/- 0.02 V/sec vs 0.09 +/- 0.01 V/sec, P < 0.001) than slow PV pacemaker cardiomyocytes (n = 65). Moreover, the PV beating rates correlated well with the slope of diastolic depolarization and maximum diastolic potential with a linear regression. As compared to those in slow PV pacemaker cardiomyocytes, the fast PV pacemaker cardiomyocytes had smaller I(to) and I(K1), and larger I(f) but with similar I(Ksus,)I(Kr), and transient inward currents. However, only few fast (2/34) and slow (1/23) PV pacemaker cardiomyocytes contained barium-sensitive hyperpolarization-activated time-dependent current (I(KH))(.) CONCLUSIONS AND IMPLICATIONS:The fast and slow PV pacemaker had different electrophysiological characteristics. I(to), I(K1), and I(f) may regulate the beating rates of PV pacemaker cardiomyocytes.

authors

Chen YC,Pan NH,Cheng CC,Higa S,Chen YJ,Chen SA

doi

10.1111/j.1540-8167.2009.01480.x

subject

Has Abstract

pub_date

2009-09-01 00:00:00

pages

1039-45

issue

9

eissn

1045-3873

issn

1540-8167

pii

JCE1480

journal_volume

20

pub_type

杂志文章
  • Electrical activation of sinus venosus myocardium and expression patterns of RhoA and Isl-1 in the chick embryo.

    abstract:UNLABELLED:Electrical Activity and RhoA in the Embryo. INTRODUCTION:Myocardium at the venous pole (sinus venosus) of the heart has gained clinical interest as arrhythmias can be initiated from this area. During development, sinus venosus myocardium is incorporated to the primary heart tube and expresses different mark...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2010.01790.x

    authors: Vicente-Steijn R,Kolditz DP,Mahtab EA,Askar SF,Bax NA,VAN DER Graaf LM,Wisse LJ,Passier R,Pijnappels DA,Schalij MJ,Poelmann RE,Gittenberger-DE Groot AC,Jongbloed MR

    更新日期:2010-11-01 00:00:00

  • Clinical outcome of very late recurrence of atrial fibrillation after catheter ablation of paroxysmal atrial fibrillation.

    abstract:INTRODUCTION:High recurrence rate is still a major problem associated with ablation of paroxysmal atrial fibrillation (AF). Most of the recurrences occur within 6 months after ablation. The characteristics of very late recurrent AF (>12 months after ablation) have not been reported. METHODS AND RESULTS:Two hundred sev...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2003.03047.x

    authors: Hsieh MH,Tai CT,Tsai CF,Lin WS,Lin YK,Tsao HM,Huang JL,Ueng KC,Yu WC,Chan P,Ding YA,Chang MS,Chen SA

    更新日期:2003-06-01 00:00:00

  • Radiofrequency catheter ablation of atrial fibrillation in athletes referred for disabling symptoms preventing usual training schedule and sport competition.

    abstract:INTRODUCTION:Atrial fibrillation (AF) may occasionally affect athletes by impairing their ability to compete, and leading to noneligibility at prequalification screening. The impact of catheter ablation (CA) in restoring full competitive activity of athletes affected by AF is not known. The aim of our study was to inve...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1540-8167.2007.01077.x

    authors: Furlanello F,Lupo P,Pittalis M,Foresti S,Vitali-Serdoz L,Francia P,De Ambroggi G,Ferrero P,Nardi S,Inama G,De Ambroggi L,Cappato R

    更新日期:2008-05-01 00:00:00

  • Description and evaluation of the Res-Q Arrhythmia Control Device.

    abstract::The Res-Q Arrhythmia Control Device (Intermedics Inc.) is one of the latest entries into the growing implantable cardioverter defibrillator (ICD) market. Dysrhythmias are classified according to their zone of detection, with a bradycardia zone, up to 3 tachycardia zones, and a fibrillation zone. Detection criterion, t...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1540-8167.1995.tb00766.x

    authors: Miller RE,Wilkoff BL

    更新日期:1995-02-01 00:00:00

  • Clinical efficacy of open-irrigated electrode cooled with half-normal saline for initially failed radiofrequency ablation of idiopathic outflow tract ventricular arrhythmias.

    abstract:BACKGROUND:Acute failure of radiofrequency ablation (RFA) of ventricular arrhythmias (VAs) occur in 10%-20% of patients and is partly attributed to inadequate lesion depth acquired with standard ablation protocols. Half-normal saline (HNS)-irrigation is a promising strategy to improve the success rate of VA ablation. ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.14057

    authors: Chung FP,Vicera JJB,Lin YJ,Chang SL,Lo LW,Hu YF,Lin CY,Tuan TC,Chao TF,Liao JN,Chang TY,Salim S,Liu CM,Chuang CM,Chen CC,Chin CG,Wu CI,Chou CY,Chen SA

    更新日期:2019-09-01 00:00:00

  • Long-term effects of biatrial synchronous pacing to prevent drug-refractory atrial tachyarrhythmia: a nine-year experience.

    abstract:INTRODUCTION:Results of previous studies suggest that atrial resynchronization by multisite atrial pacing may contribute to prevention of recurrences in patients with drug-refractory atrial tachyarrhythmias and significant intra-atrial conduction delay. METHODS AND RESULTS:To verify this hypothesis, a prospective nonc...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2000.tb01752.x

    authors: D'Allonnes GR,Pavin D,Leclercq C,Ecke JE,Jauvert G,Mabo P,Daubert JC

    更新日期:2000-10-01 00:00:00

  • Transseptal access for left atrial ablation: the catheter-probing techniques are not without risk.

    abstract:BACKGROUND:Transseptal puncture (TP) is a prerequisite for LA ablations. LA access can be gained by catheter probing in case of PFO (trans-PFO method) or puncture of the interatrial septum (IAS) using a transseptal needle. A 2nd access can again be gained via PFO, a 2nd TP or catheter probing of the previous puncture s...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.12356

    authors: Lehrmann H,Schneider J,Jadidi AS,Park CI,Schiebeling-Römer J,Allgeier J,Arentz T,Weber R

    更新日期:2014-05-01 00:00:00

  • Is pulmonary vein isolation enough for persistent atrial fibrillation?

    abstract::Pulmonary vein isolation (PVI) is a well-established treatment for atrial fibrillation (AF); however, studies report suboptimal outcomes in persistent AF. Adjuvant ablation targeting the substrate outside the pulmonary veins has been proposed to improve the success rates of the procedure. In this review, we summarize ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/jce.14381

    authors: Terricabras M,Verma A

    更新日期:2020-08-01 00:00:00

  • Patient-reported outcomes and subsequent management in atrial fibrillation clinical practice: Results from the Utah mEVAL AF program.

    abstract:BACKGROUND:Atrial fibrillation (AF) significantly reduces health-related quality of life (HRQoL), previously measured in clinical trials using patient-reported outcomes (PROs). We examined AF PROs in clinical practice and their association with subsequent clinical management. METHODS:The Utah My Evaluation (mEVAL) pro...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.14795

    authors: Zenger B,Zhang M,Lyons A,Bunch TJ,Fang JC,Freedman RA,Navaravong L,Piccini JP,Ranjan R,Spertus JA,Stehlik J,Turner JL,Greene T,Hess R,Steinberg BA

    更新日期:2020-12-01 00:00:00

  • Characterization of paroxysmal and persistent atrial fibrillation in the human left atrium during initiation and sustained episodes.

    abstract:INTRODUCTION:Atrial fibrillation (AF) in the left atrium (LA) is poorly defined in terms of regional differences in the degree of organization, characteristics of paroxysmal and persistent variants, and electrophysiologic events that develop at the onset of episodes. METHODS AND RESULTS:The study population consisted ...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2002.00525.x

    authors: Ndrepepa G,Karch MR,Schneider MA,Weyerbrock S,Schreieck J,Deisenhofer I,Zrenner B,Schömig A,Schmitt C

    更新日期:2002-06-01 00:00:00

  • Long term performance and safety of His bundle pacing: A multicenter experience.

    abstract:INTRODUCTION:Several single-center short-term studies have demonstrated the feasibility, safety, and positive clinical outcomes of permanent His bundle pacing (HBP). We performed a retrospective study to evaluate long-term technical and safety performances of HBP in a large population of pacemaker patients from two dif...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,多中心研究

    doi:10.1111/jce.14063

    authors: Zanon F,Abdelrahman M,Marcantoni L,Naperkowski A,Subzposh FA,Pastore G,Baracca E,Boaretto G,Raffagnato P,Tiribello A,Dandamudi G,Vijayaraman P

    更新日期:2019-09-01 00:00:00

  • Long-term efficacy of single procedure remote magnetic catheter navigation for ablation of ischemic ventricular tachycardia: a retrospective study.

    abstract:BACKGROUND:Remote magnetic navigation (RMN) aims to reduce some inherent limitations of manual radiofrequency (RF) ablation. However, data comparing the effectiveness of both methods are scarce. This study evaluated the acute and long-term success of RMN guided versus manual RF ablation in patients with ischemic sustai...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2011.02243.x

    authors: Dinov B,Schönbauer R,Wojdyla-Hordynska A,Braunschweig F,Richter S,Altmann D,Sommer P,Gaspar T,Bollmann A,Wetzel U,Rolf S,Piorkowski C,Hindricks G,Arya A

    更新日期:2012-05-01 00:00:00

  • Fragmented, long-duration, low-amplitude electrograms characterize the origin of focal atrial tachycardia.

    abstract:BACKGROUND:Focal atrial tachycardias (FAT) originate from areas with poor cell-to-cell coupling. Due to cellular uncoupling extracellular potentials become fractionated. The degree of fragmentation may be used to identify the site of origin of FAT prior to catheter ablation. We studied electrical fragmentation in relat...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 临床试验,杂志文章

    doi:10.1111/j.1540-8167.2006.00568.x

    authors: De Groot NM,Schalij MJ

    更新日期:2006-10-01 00:00:00

  • Targeted ablation of specific electrogram patterns in low-voltage areas after pulmonary vein antral isolation in persistent atrial fibrillation: Termination to an organized rhythm reduces atrial fibrillation recurrence.

    abstract:BACKGROUND:Ablation strategies have been developed to improve outcomes in patients with persistent atrial fibrillation (PsAF). However, the impact of atrial fibrillation (AF) termination on late AF recurrence is not well known. The aim of our study was to evaluate the impact of AF termination to atrial tachycardia (AT)...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.13763

    authors: Efremidis M,Vlachos K,Letsas KP,Bazoukis G,Martin R,Frontera A,Asvestas D,Saplaouras A,Kitamura Τ,Georgopoulos S,Valkanas K,Karamichalakis N,Takigawa M,Sideris A,Derval N,Sacher F,Jais P

    更新日期:2019-01-01 00:00:00

  • Increased dispersion of repolarization time determined by monophasic action potentials in two patients with familial idiopathic ventricular fibrillation.

    abstract:INTRODUCTION:The role of increased dispersion of repolarization in the genesis of torsades de pointes in patients with long QT syndrome has been clarified, but its role in the genesis of idiopathic ventricular fibrillation (VF) is not yet known. To investigate the pathogenesis of VF, we recorded monophasic action poten...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.1998.tb00869.x

    authors: Matsuo K,Shimizu W,Kurita T,Suyama K,Aihara N,Kamakura S,Shimomura K

    更新日期:1998-01-01 00:00:00

  • Ventricular tachycardia storm after initiation of biventricular pacing: incidence, clinical characteristics, management, and outcome.

    abstract:INTRODUCTION:Cardiac resynchronization therapy (CRT) or biventricular pacing (BVP) is becoming an important treatment option in patients with severe congestive heart failure (CHF) and electrical dyssynchrony. When combined with implantable cardioverter-defibrillator (ICD) therapy, cardiac resynchronization therapy with...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2008.01122.x

    authors: Nayak HM,Verdino RJ,Russo AM,Gerstenfeld EP,Hsia HH,Lin D,Dixit S,Cooper JM,Callans DJ,Marchlinski FE

    更新日期:2008-07-01 00:00:00

  • Outcome of non-vitamin K oral anticoagulants in the treatment of left atrial/left atrial appendage thrombus in patients with nonvalvular atrial fibrillation.

    abstract:BACKGROUND:Data comparing dabigatran with rivaroxaban regarding the resolution of left atrial/left atrial appendage (LA/LAA) thrombus in patients with nonvalvular atrial fibrillation (AF) are scarce. This study aimed to compare the efficacy and safety of dabigatran vs rivaroxaban regarding the resolution of LA/LAA thro...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.14365

    authors: Lin C,Quan J,Bao Y,Hua W,Ke M,Zhang N,Jin Q,Xie Y,Wei Y,Ling T,Pan W,Wu L,Xie Y

    更新日期:2020-03-01 00:00:00

  • Ablation of epicardial macroreentrant ventricular tachycardia associated with idiopathic nonischemic dilated cardiomyopathy by a percutaneous transthoracic approach.

    abstract::Characterization of the substrate and mechanism of epicardial ventricular tachycardia (VT) associated with idiopathic nonischemic dilated cardiomyopathy is limited. We report a case of successful mapping and ablation of an epicardial VT by a percutaneous transthoracic approach in a patient with idiopathic dilated card...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2002.01164.x

    authors: Swarup V,Morton JB,Arruda M,Wilber DJ

    更新日期:2002-11-01 00:00:00

  • Radiofrequency catheter ablation of multiple morphologies of ventricular tachycardia by targeting a single region of the left ventricle.

    abstract:INTRODUCTION:As treatment options for ventricular tachycardia (VT) continue to evolve, the use of radiofrequency catheter ablation is rapidly expanding. However, in the presence of multiple morphologies of VT, achieving successful results may seem less likely. We report two patients with multiple morphologies of VT who...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.1995.tb00378.x

    authors: Underwood RD,Deshpande SS,Biehl M,Cowan M,Akhtar M,Jazayeri MR

    更新日期:1995-11-01 00:00:00

  • Baseline B-type natriuretic peptide: a gender-specific predictor of procedure-outcome in atrial fibrillation patients undergoing catheter ablation.

    abstract:BACKGROUND:Close association between atrial fibrillation (AF) and brain natriuretic peptide (BNP) has been demonstrated by several studies. Important gender differences exist in AF patients including a higher plasma BNP level in women. Therefore, it is imperative to evaluate the relationship between AF and BNP separate...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2011.02036.x

    authors: Mohanty S,Mohanty P,Di Biase L,Rong B,Burkhardt D,Gallinghouse JG,Horton R,Sanchez JE,Bailey S,Zagrodzky J,Natale A

    更新日期:2011-08-01 00:00:00

  • Approach to catheter ablation of left atrial flutters.

    abstract::Left atrial tachycardias (ATs) most commonly occur after catheter or surgical ablation of atrial fibrillation and in patients with atrial myopathies. Pre-existing scar in the left atrium (LA) can result in complex circuits, sometimes with narrow channels that can be detected with high-resolution mapping. The most comm...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/jce.14209

    authors: Markowitz SM,Thomas G,Liu CF,Cheung JW,Ip JE,Lerman BB

    更新日期:2019-12-01 00:00:00

  • Incidence of ablation-induced esophageal injury associated with high-power short duration temperature-controlled pulmonary vein isolation using a specialized open-irrigated ablation catheter: A retrospective single-center study.

    abstract:INTRODUCTION:To evaluate short-term efficacy and incidence of ablation-induced endoscopically detected esophageal injury in patients undergoing high-power, short-duration (HPSD) pulmonary vein isolation using a novel irrigated radiofrequency ablation catheter and ablation generator setup. METHODS AND RESULTS:Atrial fi...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.14883

    authors: Piringer R,Deneke T,Foldyna B,Sonne K,Nentwich K,Ene E,Barth S,Lüsebrink U,Berkovitz A,Halbfass P

    更新日期:2021-01-13 00:00:00

  • Mitral valve prolapse and ventricular arrhythmias: observations in a patient with a 20-year history.

    abstract:INTRODUCTION:Ventricular arrhythmias are a common feature in patients with mitral valve prolapse. In an attempt to determine the origin and underlying electrophysiologic mechanism, we describe a patient with ventricular fibrillation, exercise-induced ventricular tachycardia (VT), and, at the time of diagnosis, prolapse...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.1997.tb00793.x

    authors: Wilde AA,Düren DR,Hauer RN,deBakker JM,Bakker PF,Becker AE,Janse MJ

    更新日期:1997-03-01 00:00:00

  • Atrial fibrosis in non-atrial fibrillation individuals and prediction of atrial fibrillation by use of late gadolinium enhancement magnetic resonance imaging.

    abstract:INTRODUCTION:Besides the traditional concept of atrial fibrillation (AF) perpetuating atrial structural remodeling, there is increasing evidence that atrial fibrosis might precede AF, highlighting the need for better characterization of the fibrotic substrate. We aimed to assess atrial fibrosis by use of late gadoliniu...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.13846

    authors: Siebermair J,Suksaranjit P,McGann CJ,Peterson KA,Kheirkhahan M,Baher AA,Damal K,Wakili R,Marrouche NF,Wilson BD

    更新日期:2019-04-01 00:00:00

  • Change in the retrograde atrial activation sequence following radiofrequency modification of the atrioventricular node: implications for the electrophysiologic circuit of a variant of atrioventricular nodal reentrant tachycardia.

    abstract:INTRODUCTION:Despite the great success in treating AV nodal reentrant tachycardia (AVNRT) with radiofrequency modification of the AV node, the dimensions of the electrophysiologic circuit of this arrhythmia remain unclear, and simple models fail to explain all tachycardia-related phenomena. METHODS AND RESULTS:We desc...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1046/j.1540-8167.2003.02100.x

    authors: Dizon J,Reiffel J,Kassotis J,Woollett I,Garan H

    更新日期:2003-05-01 00:00:00

  • Apamin-sensitive calcium-activated potassium currents in rabbit ventricles with chronic myocardial infarction.

    abstract:INTRODUCTION:The apamin-sensitive small-conductance calcium-activated potassium current (IKAS ) is increased in heart failure. It is unknown if myocardial infarction (MI) is also associated with an increase of IKAS . METHODS AND RESULTS:We performed Langendorff perfusion and optical mapping in 6 normal hearts and 10 h...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.12176

    authors: Lee YS,Chang PC,Hsueh CH,Maruyama M,Park HW,Rhee KS,Hsieh YC,Shen C,Weiss JN,Chen Z,Lin SF,Chen PS

    更新日期:2013-10-01 00:00:00

  • Sequential His bundle and left ventricular pacing for cardiac resynchronization.

    abstract:INTRODUCTION:Fusion of left ventricular pacing with intrinsic conduction provides superior resynchronization compared to biventricular pacing. His bundle pacing (HBP) preserves intrinsic conduction and allows for constant fusion with left ventricular pacing. This study evaluated sequential His bundle and left ventricul...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/jce.14674

    authors: Deshmukh A,Sattur S,Bechtol T,Heckman LIB,Prinzen FW,Deshmukh P

    更新日期:2020-09-01 00:00:00

  • Atrial fibrosis quantified using late gadolinium enhancement MRI is associated with sinus node dysfunction requiring pacemaker implant.

    abstract:INTRODUCTION:Sinus node dysfunction (SND) commonly manifests with atrial arrhythmias alternating with sinus pauses and sinus bradycardia. The underlying process is thought to be because of atrial fibrosis. We assessed the value of atrial fibrosis, quantified using late gadolinium enhanced-MRI (LGE-MRI), in predicting s...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2011.02140.x

    authors: Akoum N,McGann C,Vergara G,Badger T,Ranjan R,Mahnkopf C,Kholmovski E,Macleod R,Marrouche N

    更新日期:2012-01-01 00:00:00

  • Cerebral diffusion-weighted magnetic resonance imaging: a tool to monitor the thrombogenicity of left atrial catheter ablation.

    abstract:INTRODUCTION:Cerebral embolism and stroke are feared complications of left atrial catheter ablation such as pulmonary vein (PV) ablation. In order to assess the thrombogenicity of left atrial catheter ablation, knowledge of both clinically evident as well as silent cerebral embolism is important. The aim of the current...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章

    doi:10.1111/j.1540-8167.2005.00279.x

    authors: Lickfett L,Hackenbroch M,Lewalter T,Selbach S,Schwab JO,Yang A,Balta O,Schrickel J,Bitzen A,Lüderitz B,Sommer T

    更新日期:2006-01-01 00:00:00

  • Autonomic dysfunction after catheter ablation.

    abstract::Autonomic dysfunction may occur as a consequence of radiofrequency (RF) catheter ablation of a variety of supraventricular tachycardias. Effects suggestive of autonomic dysfunction that may be seen acutely during the ablation procedure include sudden profound slowing of the sinus rate or transient AV block. These abno...

    journal_title:Journal of cardiovascular electrophysiology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1540-8167.1996.tb00550.x

    authors: Friedman PL,Stevenson WG,Kocovic DZ

    更新日期:1996-05-01 00:00:00