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Mapping adverse drug reactions in chemical space.

Abstract：

:We present a novel method to better investigate adverse drug reactions in chemical space. By integrating data sources about adverse drug reactions of drugs with an established cheminformatics modeling method, we generate a data set that is then visualized with a systems biology tool. Thereby new insights into undesired drug effects are gained. In this work, we present a global analysis linking chemical features to adverse drug reactions.

journal_name

J Med Chem

journal_title

Journal of medicinal chemistry

authors

Scheiber J,Jenkins JL,Sukuru SC,Bender A,Mikhailov D,Milik M,Azzaoui K,Whitebread S,Hamon J,Urban L,Glick M,Davies JW

doi

10.1021/jm801546k

subject

Has Abstract

pub_date

2009-05-14 00:00:00

pages

3103-7

issue

9

eissn

0022-2623

issn

1520-4804

journal_volume

52

pub_type

杂志文章

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