[Post-operative analgesia with sub-arachnoid fentanyl: ventilatory effects in elderly patients].

Abstract:

:Twenty eight elderly patients scheduled for urologic surgery were randomly assigned to receive in a double blind fashion subarachnoid hyperbaric bupivacaine 15 mg with the addition of 50 micrograms (group A, n = 7), 25 micrograms (group B, n = 7), 12.5 micrograms (group C, n = 7), of fentanyl or 1 ml of saline (group D, n = 7) for a total volume of 4 ml. The pattern of breathing and the ventilatory response to CO2 were studied before 90, 150, 480 minutes after the subarachnoid injection. In group A mild pruritus and sedation occurred in 5 patients, nausea, vomiting and periodic breathing occurred in 2 patients. In group B mild pruritus and sedation were observed in 4 patients, nausea, vomiting in 2 patients. No significant changes in VE, Vt/Ti and Ti/Ttot were observed between the groups. Patients receiving 50 micrograms of fentanyl showed a slope VE/PET CO2 significantly below baseline values at 90 and 150 minutes (p less than 0.05). In this group the baseline values were restored after 480 minutes. No side effects were observed in group C and D. 25 micrograms fo fentanyl is the only dose with a significant analgesic effect without any respiratory depression.

journal_name

Minerva Anestesiol

journal_title

Minerva anestesiologica

authors

Celleno D,Muratori F,Capogna G,Cipriani G,Emanuelli M,Sebastiani M,Costantino P,Varrassi G

subject

Has Abstract

pub_date

1991-04-01 00:00:00

pages

131-6

issue

4

eissn

0375-9393

issn

1827-1596

journal_volume

57

pub_type

临床试验,杂志文章,随机对照试验
  • Update on anesthetic complications of robotic thoracic surgery.

    abstract::In the last decade, there has been increasing use of the da Vinci® robot surgical system to perform minimally invasive thoracic surgery. The robotic technology can be applied for surgery of the lungs, mediastinum, and esophagus. A number of case reports have been shown steep learning curve, and promising surgical outc...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Campos J,Ueda K

    更新日期:2014-01-01 00:00:00

  • [Changes in the parameters of humoral immunity due to surgical operations or trauma].

    abstract::Humoral immunity (immunoglobulins and C3) as well as nutritional conditions (serum albumin, transferrin) have been investigated in 23 patients in the acute phase after surgery and/or trauma. Immunoglobulin deficiency, well correlated with the severity of trauma, was observed in the most critically ill patients in the ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Guarducci AM,Langer M,Solca M,Radrizzani D,Carnevale-Maffè A

    更新日期:1981-08-01 00:00:00

  • Immunonutrients in critically ill patients: an analysis of the most recent literature.

    abstract::Modulation of inflammatory and immune response to critical illness has been the goal of much research in the last decade and a variety of drugs and nutrients (so called "immunonutrients") have been tested in experimental models with promising results. Though, in the clinical setting of intensive care, their efficacy h...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Annetta MG,Pittiruti M,Vecchiarelli P,Silvestri D,Caricato A,Antonelli M

    更新日期:2016-03-01 00:00:00

  • [Hemodynamic and respiratory changes during hip and knee arthroplasty. An echocardiographic study].

    abstract:BACKGROUND:The "bone cement implantation syndrome" is a rare but severe complication observed especially during the insertion of cemented prostheses in hip and knee replacement surgery. Several mechanisms are involved: effects of methylmethacrilate, embolism of fat, air and bone marrow, and release of tissue thrombopla...

    journal_title:Minerva anestesiologica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Dambrosio M,Tullo L,Moretti B,Patella V,Simone C,Calò MN,Dalfino L,Cinnella G

    更新日期:2002-06-01 00:00:00

  • [Non-invasive positive pressure mechanical ventilation in acute respiratory failure].

    abstract::Known for two centuries, positive pressure non invasive mechanical ventilation (VMNPP) has been widely applied in acute respiratory failure (IRA) only in the last ten years. The fact that VMNPP is able to improve gas exchange by avoiding endotracheal intubation and its complications is the most attractive aspect in bo...

    journal_title:Minerva anestesiologica

    pub_type: 历史文章,杂志文章,评审

    doi:

    authors: Scala R

    更新日期:2000-10-01 00:00:00

  • New technology for noninvasive brain monitoring: continuous cerebral oximetry.

    abstract::Although the central nervous system is the primary endpoint of most general anesthetics, it is still the least monitored organ in clinical anesthesiology. In the last decade, technological research has expanded the application of near-infrared spectroscopy to allow continuous, non-invasive, and bedside monitoring of c...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Casati A,Spreafico E,Putzu M,Fanelli G

    更新日期:2006-07-01 00:00:00

  • [Loco-regional block in ophthalmic surgery: single drug or drug combination with hyaluronidase? Randomized prospective study].

    abstract:UNLABELLED:The aim of this study is the comparison between the use of bupivacaine alone and a mixture of bupivacaine, mepivacaine and hyaluronidase in both retrobulbar and peribulbar blockades for eye surgery. Three hundred ninety-nine consecutive adult patients scheduled for cataract surgery with regional anaesthesia ...

    journal_title:Minerva anestesiologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Costa P,Papurel Begin G,Coaloa M,Villa C,Ravera E,Hellmann F,Di Giovanni M,Bono D

    更新日期:1999-11-01 00:00:00

  • Postanaesthetic shivering. Epidemiology, pathophysiology and approaches to prevention and management.

    abstract::Postanaesthetic shivering is one of the leading causes of discomfort for patients recovering from general anesthesia. During EMG records, the distinguishing factor from shivering in fully awake patients is the existence of clonus similar to that recorded in patients with spinal cord transection. They coexist with the ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Alfonsi P

    更新日期:2003-05-01 00:00:00

  • Renal effects of low dose aprotinin in pediatric cardiac surgery.

    abstract::Two groups of 15 children aged from 15 days to 6 years, undergoing surgery on cardiopulmonary by-pass for congenital heart disease have been retrospectively analyzed. Group A received a low-dose aprotinin treatment (30,000 KIU/kg in the priming solution); group C (control group) did not receive any aprotinin. Groups w...

    journal_title:Minerva anestesiologica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Ranucci M,Corno A,Pavesi M,Cirri S,Menicanti L,Frigiola A,Celoria R,Ditta A,Boncilli A,Conti D

    更新日期:1994-07-01 00:00:00

  • [Mortality in pediatric anesthesia].

    abstract:UNLABELLED:In last the 50 years many studies have described the causes of mortality. In newborns and infants between 5 and 6 months the risk is higher. The heart is not developed as in older/grown child and these infants need more oxygen than the older ones. Probably, the interaction or interference of positive pressur...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Rothstein P

    更新日期:2004-05-01 00:00:00

  • Non-invasive ventilation outside the Intensive Care Unit for acute respiratory failure.

    abstract::Non invasive ventilation (NIV) has been shown to be an effective therapy in selected patients with acute respiratory failure. Due to its benefit and relative ease of use, NIV is frequently used. In addition, the shortage and high cost of intensive care beds have prompted the use of NIV outside the intensive care unit....

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Chiumello D,Conti G,Foti G,Giacomini Matteo M,Braschi A,Iapichino G

    更新日期:2009-07-01 00:00:00

  • Reduction of operating and recovery room times and overnight hospital stays with interscalene blocks as sole anesthetic technique for rotator cuff surgery.

    abstract:BACKGROUND:The effort to decrease hospital stays and to increase operating room efficacy has become an important consideration in the practice of anesthesia. METHODS:Fifty-three patients who underwent shoulder rotator cuff repair in the sitting position were divided into four groups according to the anesthesia techniq...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Chelly JE,Greger J,Al Samsam T,Gebhard R,Masson M,Matuszczak M,Sciard D

    更新日期:2001-09-01 00:00:00

  • Acute reduction of cerebrospinal fluid volume prior to spinal anesthesia: implications for sensory block extent.

    abstract:BACKGROUND:Multiple patient and clinical characteristics contribute to the variable outcome of spinal anesthesia (SPA). Acute reduction of cerebrospinal fluid (CSF) volume may alter the effect of SPA. The objective of the present study was to test if aspiration of 10 mL CSF immediately prior to SPA is associated with h...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:10.23736/S0375-9393.20.14138-5

    authors: Bjurström MF,Mattsson N,Harsten A,Dietz N,Bodelsson M

    更新日期:2020-06-01 00:00:00

  • [An index of daily intensive care unit activity].

    abstract:OBJECTIVE:To set up an index for the evaluation of type of interventions and procedures applied a prerequisite for the evaluation of appropriateness of ICU's activity. DESIGN:Observation prospective study. PATIENTS:2507 patients out of the 5030 enrolled in the cohort study. MEASUREMENTS:A cross-sectional assessment ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Rotelli S,Iapichino G,Colombo A,Apolone G,Brazzi L,Calappi E,Leonetti C

    更新日期:1997-11-01 00:00:00

  • QT interval and QT dispersion during the induction of anesthesia and tracheal intubation: a comparison of remifentanil and fentanyl.

    abstract:BACKGROUND:The aim of this paper was to determine if there were any significant differences between the effects of fentanyl delivered as a bolus or remifentanil delivered as a continuous infusion on the QT interval and QT dispersion (QTD) during the induction of anesthesia and tracheal intubation. METHODS:This was a p...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Cafiero T,Di Minno RM,Di Iorio C

    更新日期:2011-02-01 00:00:00

  • COX-2 inhibitors: pharmacological data and adverse effects.

    abstract::The nonsteroidal anti-inflammatory drugs (NSAIDs) cover a wide range of selectivity, from the nonselective cyclooxygenase (COX) inhibitors to the preferential COX-2, and the newest coxibs, selective COX-2, with 1000-fold selectivities for COX-2. Coxibs belong to the distinct classes of sulphonamides, methylsulphones, ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Mattia C,Coluzzi F

    更新日期:2005-07-01 00:00:00

  • [Propanidid as an antagonist: competitive inhibitor of neuromuscular plaque acetylcholinesterase].

    abstract::Propanidid is a competitive inhibitor not only of serum cholinesterase, but of neuromuscular plaque and brain acetylcholinesterase also. The I50 of plaque acetylcholinesterase occurs at much higher concentrations of anaesthetic than for serum enzyme, this may depend on the environmental conditions under which propanid...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Pesando OT,Piazza L,Berruti G,Sciandra G

    更新日期:1980-06-01 00:00:00

  • Non-invasive hemodynamic optimization in major abdominal surgery: a feasibility study.

    abstract:BACKGROUND:Today, most of the pre-emptive hemodynamic optimization algorithms are based on variables associated with invasive techniques like arterial cannulation. The non-invasive Nexfin™ technology is able to estimate continuous Cardiac Index (CI) and pulse pressure variation (PPV). However, the efficiency of an earl...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Broch O,Carstens A,Gruenewald M,Nischelsky E,Vellmer L,Bein B,Aselmann H,Steinfath M,Renner J

    更新日期:2016-11-01 00:00:00

  • [The laryngeal mask in pediatric anesthesia].

    abstract::AIM. To evaluate the validity of general anesthesia using the laryngeal mask airway (LMA) in pediatrics in a series of 163 patients. MONITORING. ETCO2 and SpO2 were evaluated five minutes after the insertion of LMA and then at five minute intervals. SpO2 was evaluated every two minutes after the removal of LMA. Use of...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Piana R,Bruno G,Meo MT,Tamanti P,Zuccaro G

    更新日期:1996-01-01 00:00:00

  • [Hormone evaluation in brain death].

    abstract:BACKGROUND:In this study, the level and the variation of a number of hormone and metabolic parameters during brain death treatment in potential organ donors have been monitored. METHODS:Thirty-nine consecutive brain-dead patients were enrolled in 3 Intensive Care Units of Regional Hospitals of the North of Italy. All ...

    journal_title:Minerva anestesiologica

    pub_type: 临床试验,杂志文章

    doi:

    authors: Gravame V,Porretti L,Cardillo M,Marchesi G,Rizzi M,Sacchi C,Candiani A,Chiaranda M,Gualandris L,Taioli E,Scalamogna M

    更新日期:1999-10-01 00:00:00

  • Airway closure, atelectasis and gas exchange during anaesthesia.

    abstract::Pulmonary gas exchange is regularly impaired during general anaesthesia with mechanical ventilation. This results in decreased oxygenation of blood. Major causes are collapse of lung tissue (atelectasis) and airway closure. Collapsed lung tissue is present in 90% of all subjects, both during spontaneous breathing and ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Hedenstierna G

    更新日期:2002-05-01 00:00:00

  • [Report of a case of spontaneous thrombolysis].

    abstract::Spontaneous thrombolysis is a quite rare event. It's not predictable through a clinical examination of the patient, but there are some markers that are supposed to be diagnostic because of the high percentage of their occurrence in coincidence with spontaneous thrombolysis. The goal of the authors is to describe a cas...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Mennini MS,D'Aiutolo V,Cerroni A

    更新日期:1993-09-01 00:00:00

  • Optimal technique for deep breathing exercises after cardiac surgery.

    abstract::Cardiac surgery patients often develop a restrictive pulmonary impairment and gas exchange abnormalities in the early postoperative period. Chest physiotherapy is routinely prescribed in order to reduce or prevent these complications. Besides early mobilization, positioning and shoulder girdle exercises, various breat...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Westerdahl E

    更新日期:2015-06-01 00:00:00

  • Clinical decision support system clears the way for perioperative goal directed therapy protocol adherence improvement: a reply.

    abstract:: ...

    journal_title:Minerva anestesiologica

    pub_type: 评论,信件

    doi:10.23736/S0375-9393.19.13586-9

    authors: Menger J,Dworschak M

    更新日期:2019-06-01 00:00:00

  • [Comparison of ketorolac/buprenorphine in the treatment of post-cholecystectomy pain].

    abstract::The authors compared the efficacy of ketorolac trometamin (30 mg i.m. every 6 hours) and buprenorphine (0.3 mg i.m. every 12 hours) in the treatment of pain following cholecystectomy. Ketorolac was found to be equally efficacious in comparison to buprenorphine and caused fewer side effects. ...

    journal_title:Minerva anestesiologica

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Crimi G,Fusto A,Asaro L,Bentivegna S,Castiglione G,Pappalardo G

    更新日期:1993-03-01 00:00:00

  • [Effectiveness of regional anesthesia for loco-regional carotid surgery. Retrospective review of 147 interventions].

    abstract::The Authors present a retrospective review that compares general anesthesia with regional anesthesia performed during carotid endarterectomy surgery. The study includes 147 procedures, performed on 144 patients: 76 had general anesthesia and 71 had regional anesthesia. After emphasizing the importance of conscience pr...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Bartoloni A,Savron F,Rigo V,Pasetto A,Spezie C,Ischia A,Perbellini A

    更新日期:1991-03-01 00:00:00

  • Antiemetic efficacy of combined aprepitant and dexamethasone in patients at high-risk of postoperative nausea and vomiting from epidural fentanyl analgesia.

    abstract:BACKGROUND:Postoperative opioid analgesia increases the incidence of postoperative nausea and vomiting (PONV). We investigated whether a combination of the neurokinin-1 antagonist aprepitant and dexamethasone decreases PONV incidence compared with dexamethasone alone in high-risk patients receiving continuous epidural ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,随机对照试验

    doi:

    authors: Kawano H,Matsumoto T,Hamaguchi E,Manabe S,Nakagawa M,Yamada A,Fujimoto M,Tada F

    更新日期:2015-04-01 00:00:00

  • [Acute cocaine poisoning in a body packer. Clinical case].

    abstract::This report takes into consideration the complications due to "body packers" cocaine absorption. In particular we report a clinical case in which severe dysrhythmias occurred. We think an early insertion of a pacemaker able to rid ectopic focus by overdriving is essential by comparison with an effective anti-dysrhythm...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Marcovigi P,Leoni S,Calbi G,Valtancoli E,Granata A,Gudenzi P,Casadei C,Ravaglia G

    更新日期:1995-03-01 00:00:00

  • Acute renal failure in rhabdomyolysis.

    abstract::Fifteen to 30% of patients develop acute renal failure (ARF) following rhabdomyolysis and rhabdomyolysis accounts for 5 to 9% of all ARF. Experimental studies revealed two critical factors that predispose to myoglobinuric ARF: hypovolemia/dehydration and aciduria. At the nephron level, three basic mechanisms underlie ...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章,评审

    doi:

    authors: Guglielminotti J,Guidet B

    更新日期:1999-05-01 00:00:00

  • No progression of Eschmann tube: case report.

    abstract::A 74-year-old patient was submitted to urgent surgery for intestinal occlusion. After the induction of the anaesthesia, tracheal intubation failed since no progression of Eshmann tracheal tube introducer was possible. The ventilation was difficult and a laryngeal mask was inserted. After oxygenation, the tracheal tube...

    journal_title:Minerva anestesiologica

    pub_type: 杂志文章

    doi:

    authors: Marini F,Rizzo L,Farnesi C,Sarti A

    更新日期:2012-02-01 00:00:00