Aortic atheromas in stroke subgroups detected by multidetector computed tomographic angiography.


BACKGROUND:The aim of this study was to investigate aortic atheromas in stroke subgroups. METHODS:Two hundred consecutive subjects had acute ischemic stroke confirmed by diffusion-weighted imaging (DWI) (195 cases) or computerized tomography (5 cases). Multidetector computed tomographic angiography (MDCTA) (16- or 64-slice) was used to detect atherosclerotic plaques in vessels. Patient data and diagnostic test results were recorded. Stroke subgroups (TOAST classification) were compared with respect to plaque features in the ascending aorta or aortic arch such as presence of at least 1 plaque, larger than 1mm thick, multiple plaques, and plaque morphology (calcific, soft, mixed and ulcerated). RESULTS:Of the patients, 20.3% were in the large-artery atherosclerosis (LAA), 29.4% had small artery occlusion (SAO), 23.8% had cardioembolism (CE), 6.6% had more than one potential cause found (MPC) and 19.8% had cryptogenic stroke (CS). Overall, 49.7% of patients had at least 1 plaque (any size) in the ascending aorta or aortic arch. The corresponding rates for subgroups were as follows: LAA 80%, SAO 50%, CE 44.7%, MPC 61.5% and CS 20.5% (p<0.001). Subgroups also differed significantly with respect to presence of multiple plaques and plaques>1mm thick. Of all plaques 93% were mixed type, of which 19% were ulcerated. CONCLUSIONS:Almost half of the stroke cases had atheroma in ascending aorta or aortic arch and most of them had a soft component. Subgroups LAA, SAO, and MPC had higher aortic atheroma density compared to CE and CS.


Clin Neurol Neurosurg


Kaya D,Yildiz E




Has Abstract


2009-06-01 00:00:00














  • Glioblastoma multiforme at the corpus callosum with spinal leptomeningeal metastasis.

    abstract::Glioblastoma multiforme (GBM) often occurs in the supratentorial white matter including corpus callosum. However, spinal leptomeningeal metastasis in cases of supratentorial GBM has been reported to be rare and there is usually a long interval between the cerebral lesion and the spinal seeding. We report here a case o...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Witoonpanich P,Bamrungrak K,Jinawath A,Wongwaisayawan S,Phudhichareonrat S,Witoonpanich R

    更新日期:2011-06-01 00:00:00

  • Central nervous system effects of current and emerging multiple sclerosis-directed immuno-therapies.

    abstract:OBJECTIVE:To review the direct and indirect effects on the central nervous system (CNS) of systemically administered immuno-modulatory therapies in use or under evaluation for the relapsing forms of multiple sclerosis (MS). METHODS:We summarize data published by our own lab and by others that delineate the effects of ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审


    authors: Antel JP,Miron VE

    更新日期:2008-11-01 00:00:00

  • Bilateral ethmoidal dural arteriovenous fistula: unexpected surgical diagnosis.

    abstract::Dural arteriovenous fistulae (DAVFs) are infrequent lesions, the most common locations of which are the cavernous, sigmoid and transverse sinuses. The cribiform plate is one of the less frequent sites for DAVFs, where they entail a high hemorrhage risk. Feeding arteries for ethmoidal DAVFs can be uni- or bilateral. Ho...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Ros de San Pedro J,Pérez CJ,Parra JZ,López-Guerrero AL,Sánchez JF

    更新日期:2010-12-01 00:00:00

  • Gangliocytomas of the sellar region: A challenging diagnosis.

    abstract::Gangliocytoma of the sellar region are extremely rare and often coexist with pituitary adenoma. Aim of this review is to collect all the cases reported in literature and to summarize the most recent literature evidences on the subject. A systematic review was performed through PubMed searching for articles describing ...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审


    authors: Cossu G,Daniel RT,Messerer M

    更新日期:2016-10-01 00:00:00

  • Role of transcranial Doppler ultrasonography in assessing stenosis after flow diversion.

    abstract:INTRODUCTION:Patients after implantation of flow diverters (FD) due to intracranial aneurysms require radiological and clinical follow-up in view of in-stent stenosis. The aim of the study was to evaluate transcranial Doppler ultrasonography (TCD) as an alternative to more invasive digital subtraction angiography in mo...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Kocur D,Paździora P,Baron J,Rudnik A

    更新日期:2020-11-01 00:00:00

  • A missed diagnosis: acute encephalopathy with biphasic seizures and late reduced diffusion.

    abstract::Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) is a very rare encephalopathy subtype which is characterized by biphasic seizures and disturbance of consciousness in the acute stage followed in the subacute stage by restricted diffusion in the subcortical white matter and finally resultin...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 信件


    authors: Bekci T,Aslan K,Bilgici MC,Onaral CS,Yosma E

    更新日期:2014-12-01 00:00:00

  • Repeat surgery for recurrent low-grade gliomas should be standard of care.

    abstract::The importance of surgery and maximal extent of resection (EOR) is well established in primary low-grade glioma (LGG) management. However, the role of surgery in the management of recurrent LGG is less clear. A recent review on the management of recurrent LGG concluded there was insufficient evidence to recommend surg...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审


    authors: Uppstrom TJ,Singh R,Hadjigeorgiou GF,Magge R,Ramakrishna R

    更新日期:2016-12-01 00:00:00

  • Transforaminal endoscopic decompression and uninstrumented allograft lumbar interbody fusion: A feasibility study in patients with end-stage vacuum degenerative disc disease.

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Dowling Á,Bárcenas JGH,Lewandrowski KU

    更新日期:2020-09-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Ko KF,Chan KL

    更新日期:1995-05-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: van Manen SR,Bosch DA,Peeters FL,Troost D

    更新日期:1995-05-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Sharma M,Dietz N,Ugiliweneza B,Wang D,Drazin D,Boakye M

    更新日期:2019-07-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Verlooy P,Velis DN

    更新日期:1985-01-01 00:00:00

  • Desmoplastic low grade astrocytoma: a case report and review of literature.

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章,评审


    authors: Chacko G,Chandi SM,Chandy MJ

    更新日期:1995-02-01 00:00:00

  • Increased expression of Akt2 and activity of PI3K and cell proliferation with the ascending of tumor grade of human gliomas.

    abstract:OBJECTIVE:To study the expression of Akt2 and activation of PI3K in different grades of human gliomas and correlate the Akt2 expression with the proliferation activity of gliomas. METHODS:Akt2 expression and PI3K activity were examined in 48 different grades of human glioma specimens and six normal brain tissue sample...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Wang G,Kang C,Pu P

    更新日期:2010-05-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Xiao R,Abdullah KG,Miller JA,Lubelski D,Steinmetz MP,Shin JH,Krishnaney AA,Mroz TE,Benzel EC

    更新日期:2016-05-01 00:00:00

  • Morbidity following sural nerve harvesting: a prospective study.

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Martins RS,Barbosa RA,Siqueira MG,Soares MS,Heise CO,Foroni L,Teixeira MJ

    更新日期:2012-10-01 00:00:00

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    abstract::The headache associated with intercourse or masturbatory activity is a well-recognized clinical entity but pornography headache is barely mentioned. We report a young man who suffered preorgasmic headache pertaining only to pornography of specific erotic contents but not to other sexual or nonsexual act. An antecedent...

    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Chen WH,Chen KY,Yin HL

    更新日期:2018-01-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Slooff JL

    更新日期:1975-01-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Bruylant K,Crols R,Humbel RL,Appel B,De Deyn PP

    更新日期:2006-06-01 00:00:00

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    authors: Tabrizi YM,Mazhari S,Nazari MA,Zangiabadi N,Sheibani V,Azarang S

    更新日期:2013-09-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Slooff AC

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Nakagawa K,Tago M,Terahara A,Aoki Y,Sasaki T,Kurita H,Shin M,Kawamoto S,Kirino T,Otomo K

    更新日期:2000-12-01 00:00:00

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    authors: Guo F,Song L,Bai J,Zhao P,Sun H,Liu X,Yang B,Wang S

    更新日期:2012-09-01 00:00:00

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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Lin YJ,Chiu HY,Chiou MJ,Huang YC,Wei KC,Kuo CF,Hsu JT,Chen PY

    更新日期:2017-08-01 00:00:00

  • The influence of age on the peri- and postoperative clinical course in patients undergoing minimally invasive transforaminal lumbar interbody fusion techniques of the lumbar spine.

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    journal_title:Clinical neurology and neurosurgery

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    authors: Senker W,Stefanits H,Gmeiner M,Trutschnig W,Radl C,Gruber A

    更新日期:2019-07-01 00:00:00

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    更新日期:2016-08-01 00:00:00

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    pub_type: 杂志文章


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    journal_title:Clinical neurology and neurosurgery

    pub_type: 杂志文章


    authors: Go KG,Kamman RL,Mooyaart EL

    更新日期:1989-01-01 00:00:00

  • Cognitive and functional impairments in ischemic stroke patients with concurrent small vessel and large artery disease.

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    pub_type: 杂志文章


    authors: Man BL,Fu YP,Wong A,Chan YY,Lam W,Hui AC,Leung WH,Mok V,Wong KS

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    pub_type: 杂志文章


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    更新日期:2020-11-01 00:00:00